The infrared jammer is a common countermeasure for escaping the missile’s attack, but a systemic analysis for jamming effectiveness in the target-missile engagement is absent. This paper analytically elaborates on the jamming effect for a spin-scan seeker with different parameters including jamming power, frequency, and phase. First, the mathematical expression of error signal for spin-scan seeker is derived, which provides the basis for constructing a missile guidance loop in which a target at arbitrary orientation employs a jammer. Next, the jamming effect of infrared jammer with different parameters is evaluated by the magnitude of miss distance. The simulation results and corresponding theoretical analysis indicate that a greater jamming power will increase the target survival probability and the range of jamming frequency and phase can be set more flexibly. Furthermore, the jamming will be valid if the jamming frequency is close to the reticle spin frequency under the condition of a greater jamming power, which forms the jamming strategy. Finally, a frequency identification method for a missile is designed by the cat-eye effect theory through signal processing and proved to be accurate, so the jamming strategy will be more utilizable in practice. The simulation results and analysis in the present paper will provide theoretical support for infrared jamming strategy.