Cationic Surfactant Cetyltrimethylammonium Chloride Research Articles

Flexible nanohybrid substrates utilizing gold nanocubes/nano mica platelets with 3D lightning-rod effect for highly efficient bacterial biosensors based on surface-enhanced Raman scattering.

In this study, gold nanocubes (AuNCs) were quickly synthesized using the seed-mediated growth method and reduced onto the surface of two-dimensional (2D) delaminated nano mica platelets (NMPs), enabling the development of AuNCs/NMPs nanohybrids with a 3D lightning-rod effect. First, the growth-solution amount can be changed to easily adjust the AuNCs average-particle size within a range of 30-70 nm. The use of the cationic surfactant cetyltrimethylammonium chloride as a protective agent allowed the surface of AuNCs and nanohybrids to be positively charged. Positively charged nanohybrid surfaces presented a good adsorption effect for detecting molecules with negative charges on the surface. Additionally, the NMP surfaces were rich in ionic charges and provided a large specific surface area for stabilizing the growth of AuNCs. Delaminated AuNCs/NMPs nanohybrids can generate a 3D hotspot effect through self-assembly to enhance the Raman signal. Surface-enhanced Raman scattering (SERS) is highly sensitive in detecting adenine biomolecules. Its limit of detection (LOD) and Raman enhancement factor reached 10-9 M and 3.6 × 108, respectively. Excellent reproducibility was obtained owing to the relatively regular arrangement of AuNC particles, and the relative standard deviation (RSD) was 10.7%. Finally, the surface of NMPs was modified by adding the hydrophilic poly(oxyethylene)-diamine (POE2000) and amphiphilic PIB-POE-PIB copolymer at different weight ratios. The adjustment of the surface hydrophilicity and hydrophobicity of AuNCs/NMPs nanohybrids led to better adsorption and selectivity for bacteria. AuNCs/POE/NMPs and AuNCs/PIB-POE-PIB/NMPs were further applied to the SERS detection of hydrophilic Staphylococcus aureus and hydrophobic Escherichia coli, respectively. The SERS-detection results suggest that the LOD of hydrophilic Staphylococcus aureus and hydrophobic Escherichia coli reached 92 CFU mL-1 and 1.6 × 102 CFU mL-1, respectively. The AuNCs/POE/NMPs and AuNCs/PIB-POE-PIB/NMPs nanohybrids had different hydrophilic-hydrophobic affinities, which greatly improved the selectivity and sensitivity for detecting bacteria with different hydrophilicity and hydrophobicity. Therefore, fast, highly selective, and highly sensitive SERS biological-detection results were obtained.

Synergism and molecular mismatch in rhamnolipid/CTAC catanionic surfactant mixtures

Rhamnolipids represent a promising class of biosurfactants, whose industrial exploitation could potentially reduce the ecological impact of surfactant-based formulations. In this direction, the rational design of rhamnolipid mixtures with other surfactants constitutes a strategic field of research.In this work, we combine mono-rhamnolipid (mRha) with the cationic surfactant cetyltrimethylammonium chloride (CTAC). The study is conducted at pH = 7.1, so that the mRha carboxylic group is dissociated and catanionic mRha-CTAC mixtures form. The system is investigated across the entire composition range by surface tension and conductivity measurements, which show a strong synergism between the two surfactants in forming mixed aggregates, specifically in mRha-rich mixtures. No coacervation or precipitation is observed, due to the strong asymmetry between the surfactant molecular architectures, with mRha presenting a bulky headgroup and two relatively short tails compared to the single long tail of CTAC. Dynamic Light Scattering (DLS) and Small Angle Neutron Scattering (SANS) experiments show that, while the single surfactants predominantly form small micelles, their mixing results in the spontaneous formation of vesicles. Within the vesicle bilayer, the termini of the longer surfactant tails fold, assuming disordered conformations, as probed by Electron Paramagnetic Resonance (EPR) measurements.These results point to the rational design of rhamnolipid-based catanionic mixtures as a suitable tool to optimize their structural properties, constituting a solid basis for their practical applications.

Interactions of cationic surfactant-fatty alcohol monolayers with natural human hair surface: Insights from dissipative particle dynamics

Fatty alcohols (CnFAs) combined with cationic surfactants are common ingredients of lamellar-phase personal care liquids. We employ mesoscopic modelling to study.how surfactant-CnFA monolayers originating from the corresponding bilayers of the personal care liquids interact with the human hair surface above and below the fluid-gel transition temperature as well as in- and out-of-equilibrium. For the monolayer model, we consider the single-tail cationic surfactant cetyltrimethylammonium chloride (CTAC) and an excess of CnFAs with their alkyl tail length equal to or longer than the CTAC alkyl tail length. The hair surface mimics keratin surface proteins covered by a film of lipid chains covalently bonded to the proteins. Our modelling shows the formation of a dense adsorbed layer due to the interactions of the CTAC and CnFA alkyl tails with the hydrophobic hair surface. The adsorption and the behaviour of the adsorbed layer is different under fluid and gel conditions. The differences are related to the structure of the adsorbed layer as characterised by density profiles across the adsorbed layer and the orientational order parameters of the chains within the adsorbed layer. Under steady-state shearing (an approximation of real, non-equilibrium conditions), increasing the shear rate above a threshold leads to continuous or abrupt desorption of the CTAC and CnFA chains under fluid or gel conditions, respectively; the desorbed chains can then form various self-assembled structures in the bulk solution. The underlying mechanism of CTAC and CnFA desorption from the adsorbed layers is closely related to the corresponding adsorption mechanism.

The two-phase amphiphilic preconcentration based on surfactants to enrich phenolic compounds from diluted plant extracts and rat urine by micellar electrokinetic chromatography.

A novel technology by two-phase amphiphilic preconcentration based on surfactants was established for enriching phenolic compounds by micellar electrokinetic chromatography (MEKC). The cationic surfactant cetyltrimethylammonium chloride (CTAC) was combined with the anionic analytes that existed in the sample solution before injection. The boundary was formed between CTAC and sodium dodecyl sulfate (SDS) in the background solution when the sample solution was injected into the capillary, where the analytes bound inside micelles were released due to the stronger electrostatic force between SDS and CTAC. This procedure accelerated the separation of analytes from CTAC and greatly improved the enrichment efficiency. The optimal conditions were obtained after a series of optimizations, and the sensitivity enrichment factors of the four analytes were in the range of 39-93 compared to typical injections in capillary zone electrophoresis. Good linearity for matrix-matched calibrations was established for all analytes with R2 values of 0.9993-0.9997. The limits of detection (S/N=3) for kaempferol, quercetin, salvianolic acid C, and salvianolic acid B were 0.0166, 0.0292, 0.0215, and 0.0195µg/ml, respectively. The intracapillary RSDs of the analytes ranged from 0.8% to 1.3% for migration time and from 0.4% to 1.8% for peak areas. The developed method was successfully applied to the determination of phenolic compounds, the main compounds of Salvia miltiorrhiza Bge., and had been validated for the determination of spiked recoveries in rat urine.

Study on wetting behavior between CTAC and BS-12 with gas coal based on molecular dynamics simulation

To determine the influence of different types of surfactants on the wettability of gas coal from a microscopic perspective, the cationic surfactant cetyltrimethylammonium chloride (CTAC) and zwitterionic surfactant dodecyldimethylbetaine (BS-12) were selected. The effects of two different types of surfactants on the wettability of gas coal were investigated using molecular dynamics simulations. The molecular dynamics simulation results showed that the surfactant molecules could be adsorbed on the surface of gas coal molecules, and the BS-12 molecule had a stronger adsorption effect. By analyzing the relative concentration distribution curves of different systems, it could be concluded that the addition of CTAC and BS-12 increased the thickness of the adsorption layer at the water/coal interface from 21.61 Å to 27.26 Å and 32.93 Å, respectively, which is consistent with the results of the water molecular diffusion coefficient analysis. In addition, the interaction energies of CTAC and BS-12 with gas coal were −1775.18 kcal/mol and −1986.95 kcal/mol, respectively, which indicates that the adsorption process was spontaneous. Finally, contact angle experiments and X-ray photoelectron spectroscopy (XPS) analyses further verified that the wettability of BS-12 for gas coal was greater than that of CTAC.

Triangular gold nanoplates/two-dimensional nano mica platelets with a 3D lightning-rod effect as flexible nanohybrid substrates for SERS bacterial detection.

Triangular gold nanoplates (TAuNPs) were prepared by a one-step rapid growth method and then reduced and stabilized on two-dimensional nano mica nanoplatelets (NMPs). We also prepared TAuNP/NMP nanohybrids with a three-dimensional lightning-rod effect by oxidative etching. The surface of the delaminated NMPs (only 1 nm thick) is highly charged and can provide a large specific surface area; thus, it can be used as a substrate for the stable growth of gold nanoplates. In addition, by controlling relevant synthesis parameters, the edge length of the TAuNPs can be easily adjusted in the range of 30-90 nm. During reduction of the TAuNPs, the cationic surfactant cetyltrimethylammonium chloride was added as a protective agent to surround the TAuNPs; consequently, the surface was positively charged, which facilitates adsorption for detecting molecules with negative charges. When nanohybrids were used in surface-enhanced Raman spectroscopy (SERS) to detect adenine molecules, the limit of detection concentration was 10-9 M. The Raman enhancement factor was 5.7 × 107, and the relative standard deviation (RSD) was 9.8%. Finally, this method was applied to the biological detection of Staphylococcus aureus, and the surface charge and hydrophilic properties of the material significantly improved the SERS signal of S. aureus. The limit of detection concentration was 102 CFU mL-1, and the RSD was 11.2%. The TAuNP/NMP nanohybrids can provide very rapid and sensitive SERS detection of biomolecules.

Hydrogel Formation by Glutamic-acid-based Organogelator Using Surfactant-mediated Gelation.

Hydrogels formed by low-molecular-weight gelators have reversible sol-gel transition and responsiveness to various stimuli, and are used in cosmetics and drug applications. It is challenging to obtain hydrogels using novel gelators because subtle differences in their molecular architecture affect gelation. Organogelators (which form organogels) are insoluble in water, and their use as hydrogelators has not previously been considered. However, a surfactant-mediated gelation method was reported in which organogelators were solubilized in water by surfactants to form hydrogels using 12-hydroxyoctadecanoic acid. To investigate whether this method can be applied with other organogelators, the formation of hydrogel using a glutamic-acid-based organogelator was studied here. Hydrogels were formed by solubilizing 1:1 mixtures of glutamate-based organogelators, N-lauroyl-L-glutamic acid dibuthylamide, and N-2-ethylhexanoyl-L-glutamic acid dibutylamide in aqueous micellar solutions of anionic surfactant (sodium lauroyl glutamate) and cationic surfactant (cetyltrimethylammonium chloride). The minimum gelation concentration of the hydrogel was ~0.2-0.6 wt%. By changing the molar fraction of cetyltrimethylammonium chloride in the mixed surfactant, either spherical or wormlike micelles were formed. The hydrogel with wormlike micelles had a higher sol-gel transition temperature than that with spherical micelles and formed fine self-assembled fibrillar networks. Additionally, the hydrogel with the spherical micelles was elastic, whereas that with wormlike micelles was viscoelastic, suggesting that networks of the organogelators and wormlike micelles coexisted in the hydrogel from the wormlike micellar solution. Moreover, the hydrogel suppressed the reduction in the storage modulus at higher temperatures compared with the micellar aqueous solution, indicating that the elastic properties of the organogelator networks were maintained at high temperatures. The gel fibers of the hydrogel partially formed a loosely aggregated structure as the temperature increased, the fibers bundled via hydrophobic interactions, and new cross-linking points formed spontaneously. This phenomenon corresponded with an inflection point in the temperature-dependent storage modulus of the hydrogel.

Enhanced drag reduction performance by interactions of surfactants and polymers

The interactions of cationic surfactant cetyltrimethyl ammonium chloride (CTAC) and polyacrylamide (PAM) in drag reduction solutions are studied by experiments and simulations. Cryogenic Transmission Electron Microscopy shows that CTAC and PAM form aggregates with interconnected network structures, and the bridge effect from polymers can improve the network structures’ density. The associated potential of mean force (PMF) value indicates that surfactant/polymer attractions contribute to the formation of aggregates. Meanwhile, the mechanism of the enhanced drag reduction performance of surfactant/polymer solution is discussed by the extension energy of the aggregate structures. It is found that the interactions of surfactants and polymers help to improve the anti-shear performance of the surfactant micelles. Furthermore, polymers can balance micelles energy distribution, postpone the appearance of energy extreme point, and delay the rupture of micelles. This work fundamentally demonstrates that interactions and strengthened structures of micelle aggregates can intensify drag reduction in surfactant/polymer solutions.

Fluorescence quenching of chloroquine by Cu2+ in micelles

Abstract Fluorescence quenching, very often, has been employed as a suitable technique for characterization of the immediate environment of a fluorophore. This paper reports the absorption and fluorescence characteristics of an antimalarial drug, chloroquine, in presence of the salt copper chloride (CuCl2) in aqueous and micellar systems. Chloroquine fluorescence was quenched considerably by the copper ion (Cu2+); quenching ability of Cu2+ in micellar solution of the cationic surfactant cetyltrimethylammonium chloride (CTAC) is higher than that in water while for the nonionic surfactant polyoxyethylene (20) cetyl ether (Brij 58) it has much lower quenching efficiency. Downward deviations in Stern-Volmer (SV) plots were observed for all the systems. Possibly, the chloroquine molecules are inserted somewhat deeper inside the micelles of Brij 58 as compared to the CTAC micelles and in Brij 58 micelles the fluorophore might be less exposed to the aqueous phase to become available for the metal ion quenching.

Influence of Temperature and Shear Rate on Rheological Properties of CTAC/NaSal Aqueous Solution

Background: It is very important for understanding the turbulence drag-reducing mechanism and for improving product quality in the fields of pharmaceutical and chemical engineering to deeply investigate the rheological properties of surfactants solutions. Methods: The rheological properties of Cationic surfactant (Cetyltrimethyl Ammonium Chloride)/Sodium salicylate were measured and analyzed with the MCR302 rheometer. Results: The present results show that the shear viscosity of CTAC/NaSal solution with the exception of 0.9375mmol·L-1 can show the Newtonian characteristic, the shear-thickening, the shear-thinning and the stable shear properties with changing shear time. The induction time increases with a shear rate as a power law function relation tind=aγb. Conclusion: The shear viscosity of the CTAC/NaSal solution can be divided into three regions with shear rate, and its flow curve conforms to a linear function in the logarithmic coordinate. When the concentration and the shear rate are relatively high, the viscosity curve of the CTAC/NaSal solution appears "platform" at the high temperature. When the shear rate is greater than 90s-1, the shear viscosity only appears shear thinning with increasing temperature.

Surfactant tuned morphology of mesoporous β-Co(OH)2/CMC nanoflakes: a prospective candidate for supercapacitors

Innovative electrode materials are the need of the hour towards the fabrication of electrochemical energy storage systems with superior performance. In the objective of designing flexible high power supercapacitors, herein, we have synthesized β-cobalt hydroxide/carboxymethyl cellulose nanoflakes via a facile route using anionic, cationic, and non-ionic structure directing agents. When tested as a supercapacitor electrode, β-cobalt hydroxide/carboxymethyl cellulose nanoflakes prepared using cationic surfactant (cetyltrimethylammonium chloride) exhibit better electrochemical behaviour including specific capacitance (306 C g−1 at a scan rate of 2 mV s−1), excellent cycle life (89% capacitance retention even after 5000 repeated charge/discharge cycles) in an aqueous alkaline solution. Furthermore, we have designed an asymmetric supercapacitor utilizing β-cobalt hydroxide/carboxymethyl cellulose and activated carbon as electrodes which is capable of delivering an energy density of 29.7 W h kg−1 with the power density of 695 W kg−1. The notable features of this device open pathways for the new electrode materials in supercapacitors.

Molecular dynamics simulation of self-assembly and viscosity behavior of PAM and CTAC in salt-added solutions

In this study, the self-assembly of cationic surfactant cetyltrimethyl ammonium chloride (CTAC) and nonionic polymer polyacrylamide (PAM) in aqueous solution with added sodium salicylate (NaSal) as counter-ion salt is studied using a coarse-grained molecular dynamic simulation (CGMD). The microstructure evolution shows that in the mixed solutions, surfactant micelles are readily to associate with polymer and can form a new complex of CTAC and PAM with interconnected network structures, which can be attributed to the hydrophobic interactions, the attraction between acylamino and the head of CTAC, and the attraction between Sal− and acylamino. The calculation of radial distribution function for different sites also proved the aggregate of the surfactant and polymer. Then a reverse non-equilibrium molecular dynamics (RNEMD) simulation is used to investigate the rheological property of the mixed solutions, the CTAC/NaSal solution and the PAM solution. The molecular dynamics simulation demonstrates that the viscosity of the CTAC/PAM/NaSal solution is significantly higher than that of the CTAC/NaSal solution, mainly because the surfactant micelles interacted with the polymer and formed rod-like micelles.

Experimental studies on drag reduction by coupled addition of nonionic polymer poly(ethylene oxide) and cationic surfactant cetyltrimethyl ammonium chloride

AbstractMore and more attention is paid to the synergistic drag reduction by polymers and surfactants because there are serious disadvantages of the drag reduction by them alone. In order to understand the synergistic effect of the drag reduction by polymers and surfactants, in‐depth investigations are performed on the drag reduction behavior by simultaneous addition of nonionic polymer poly(ethylene oxide) (PEO) and cationic surfactant cetyltrimethyl ammonium chloride (CTAC) in a two‐dimensional channel flow. The sodium salicylate (NaSal) is added to provide counter ions for promoting micelle formation. For comparisons, the drag‐reducing behaviors of PEO and CTAC/NaSal alone are also investigated. The present results show that the synergistic effect of the drag reduction depends upon concentration combination of PEO and CTAC/NaSal. The Reynolds number range with a high drag‐reducing rate becomes wider due to the simultaneous addition of PEO & CTAC/NaSal, whereas the ultimate drag reduction rate has a minimal change. The drag reduction enhancement is a complicated and nonlinear issue, and it seems that PEO and CTAC/NaSal play different roles in the drag reduction in different Reynolds number ranges.

Formation of N-nitrosamines by micelle-catalysed nitrosation of aliphatic secondary amines.

N-Nitrosamines are an important class of potent human carcinogens and mutagens that can be present in water and wastewater. For instance, N-nitrosamines can be formed by reaction of nitrosating agents such as NO+ or N2O3 formed from nitrite under acidic conditions with secondary amine precursors by an acid-catalysed nitrosation pathway. This study investigates the catalytic effect of cationic and anionic micelles on the nitrosation of secondary aliphatic amines in the presence of nitrite at different pH values. The results of this study demonstrate that the nitrosation of hydrophobic secondary amines (e.g., dipropylamine and dibutylamine) by nitrite was significantly enhanced in the presence of micelles of the cationic surfactant cetyltrimethylammonium chloride whereas anionic micelles formed by sodium dodecylsulfate did not significantly enhance the formation of N-nitrosamines. Rate enhancements of up to 100-fold were observed for the formation of N-nitrosodibutylamine in the presence of cetyltrimethylammonium chloride. The magnitude of the catalytic effect of cationic micelles on the nitrosation reaction depended mainly of the hydrophobicity of the amine precursors (i.e., alkyl chain length), the stability and the charge of the micelles and pH. One important enhancement factor is the lowering of the pKa of the precursor alkylammonium ion due to the electrical potential at the micelle-water interface by up to ∼2.5 pH units. These results suggest that cationic micelle-forming surfactants might play a role in the formation of N-nitrosamines in wastewater, consumer products and in industrial processes using high concentrations of cationic surfactants.

EXPERIMENTAL STUDY ON THE COLLABORATIVE DRAG REDUCTION PERFORMANCE OF A SURFACTANT SOLUTION IN GROOVED CHANNELS

Abstract Turbulence with a relatively larger vortex is obtained in drag-reducing surfactant solution, which provides an excellent condition for the application of small scale grooves. In this work, the coupling drag reduction performance of surfactant solution and grooves was experimentally investigated to explore the complementary possibility between their drag reduction mechanisms. The cationic surfactant cetyltrimethyl ammonium chloride (CTAC) mixed with the counterion salt sodium salicylate (NaSal) was experimented in smooth or grooved channel, respectively, at the mass concentrations of 50-150 ppm. It was found that the surfactant solutions gave more effective drag reduction in the grooved channel by the interaction between the restriction effect and peak effect of grooves. Moreover, the critical temperature and critical Reynolds number of the surfactant solution were smaller in the grooved channel, and the friction factor in the grooved channel increased much more rapidly than that in the smooth channel when Re is larger than a critical value.

Cetyltrimethylammonium chloride (CTAC) catalyzed one-pot synthesis of novel coumarin-4H-pyran conjugates in aqueous media

Novel fluorescent coumarin-4H-pyran conjugates were achieved by three-component reactions of various synthetic β-ketoesters with aldehydes and malononitrile in aqueous media. Besides mild reaction conditions, operational simplicity, absence of tedious separation procedures, using of inexpensive and nontoxic commercially available cationic surfactant cetyltrimethylammonium chloride (CTAC) as a catalyst are the prominent advantage of this method.

Multidimensional polyaniline structures from micellar templates

Polyaniline (PANI) multidimensional (MD) structures (i.e., flowers, sheets, and plates) are successfully synthesized by adjusting the dosage of cationic surfactant cetyltrimethylammonium chloride (CTAC) in the range of 0.050–0.50 g in static HCl solution (0.010 M) at room temperature without stirring. CTAC micellar templates consisting of quaternary ammonium cations and binary persulfate anions direct the fabrication of PANI MD structures. On the basis of the employment of CTAC, the effect of pH value on PANI morphologies is investigated in detail, and followed by the obtainment of other PANI structures, including nanobelts, net-like structures, and particulates. Among the PANI MD structures, PANI sheets in micron size have good dispersibility and excellent processability, which are due to the synergistic effect of PANI’s suitable size and appropriate CTAC molecules. The results and strategies presented here provide opportunities to obtain good water dispersibility to conduct polymer structures with big size.

Investigation on the co-modification process of montmorillonite by anionic and cationic surfactants

To study how anionic surfactant sodium dodecyl sulfonate (SDS) and cationic surfactant cetyltrimethylammonium chloride (CTAC) enter the interlayer spaces of montmorillonite, montmorillonite, CTAC and SDS were exchanged consecutively and simultaneously. Three parameters were investigated: reaction times, surfactants contents and addition sequences. The results of XRD, thermal analysis and sulfur analysis stated that SDS could not intercalate into montmorillonite interlayer space alone. However, it can enter the interlayer space of montmorillonite in the presence of CTAC. The addition sequences of cationic and anionic surfactants affect the d-value and thermal stability of anionic-cationic montmorillonite. The data obtained from elemental analysis clarified the steps of this multistep reaction sequence and a mechanistic scheme has been proposed: a portion of cationic surfactants intercalate into the interlayer spaces of montmorillonite by cation exchange firstly, and then the anionic surfactant enter the interlayer spaces of montmorillonite by the synergistic effect with cationic surfactants. Molecular simulation indicated the arrangement of cationic and anionic surfactants intercalated into montmorillonite interlayer space.

New pressure-assisted sweeping on-line preconcentration for highly polar environmentally relevant nitrosamines: Part 2. Cationic and anionic surfactants with zero-flow capillaries.

We recently introduced a pressure-assisted sweeping-reversed migration-EKC (RM-EKC) method for preconcentration of neutral polar N-nitrosamines with low affinity for the micellar phase. The type of surfactant and phase ratio are dominant factors in dictating the magnitude of interactions between analyte and micellar phase, thus four surfactants (anionic and cationic) with a range of functionalities (SDS, ammonium perfluorooctanoate (APFO), bile salts, and cetyltrimethylammonium chloride (CTAC)) were evaluated for sweeping-RM-EKC of highly polar N-nitrosamines. All gave acceptable results for sweeping-RM-EKC when used in high concentrations (≥200 mM) with low EOF. While no single surfactant was superior by all measures, all but the bile salts had useful performance characteristics. APFO showed the narrowest peak widths and highest number of theoretical plates, though two species co-migrated at all concentrations (25-300 mM); SDS and the cationic surfactant CTAC also showed good separation characteristics and could resolve all peaks, but CTAC had wider separation window. Various types of capillaries coated for EOF control were compared for use with anionic and cationic surfactants. A commercial zero-EOF capillary coated with a polymer bearing sulfonic acid functional groups showed superior EOF suppression and reproducibility of migration time with all surfactants.

Effect of organic additives and temperature on the micellization of cationic surfactant cetyltrimethylammonium chloride: Evaluation of thermodynamics

In the present study, we report the effect of organic additives and temperature on the micellization of cationic surfactant cetyltrimethylammonium chloride (CTAC). The micellization behavior of CTAC was studied at different fixed temperatures and fixed concentrations of organic additives (viz., sugar and amino acid) in aqueous solutions. The critical micelle concentrations (CMC) of CTAC were measured by the conductivity and dye solubilization methods. The CMC values first increase with increasing temperature (up to 298K) and then decrease with increasing temperatures; whereas the increasing trend was found to be with organic additive concentrations. The thermodynamic parameters (viz., standard Gibbs energy (ΔGm0), standard enthalpy (ΔHm0), and standard entropy (ΔSm0) of micellization of CTAC) are evaluated. The thermodynamic parameter values clearly indicate less stability of the CTAC solution in the presence of organic additives.