"Indigenization" is a process that presents a blend and adaptable feature by combining foreign elements with the local natural environment and cultural factors. Church buildings are the most tangible manifestation of the "indigenization" of Christianity. This paper discusses the application of indigenization techniques in modern Chinese Catholic church architecture from four aspects: layout, structure, materials, and decoration. In terms of layout, indigenization is reflected in space, plan, and orientation. The space mainly imitates traditional Western-style churches and simplifies with the simplification of function. In terms of plan form, the basic rectangular space is retained and combined with local architectural features to evolve into some new variants. Orientation, some churches have absorbed local building orientation patterns. In terms of structural indigenization, the main materials are stone, brick, and soil, and the building structure is mainly supported by load-bearing walls and wooden beams. In terms of material selection, indigenization techniques are mainly based on regional resource conditions and are combined with the characteristics of local residences and climate conditions. The choice of building materials is made by considering the availability, processing difficulty, and physical properties of materials. The application of decorative indigenization often borrows common decoration techniques from local residential buildings and combines them with traditional Chinese culture to create a unique Chinese and Western fusion style building, making the church better integrated into the local architectural community and accelerating local residents' acceptance of Catholicism.