Urbanization is inevitably accompanied by drastic changes in regional land use and therefore presents an evident influence on ecosystems. Habitat quality (HQ) reflects the ability of a habitat to provide suitable conditions for the survival of an individual or population, and clarifying the interrelationships between urbanization level (UL) and HQ provides insights into sustainable urbanzation and ecosystems conservation. Much attention has focused on how urbanization related to HQ at multi-scales, but few studies have analyzed the interactive coercive relationships between UL and HQ on the global county level. To address this gap, we adopted the bivariate spatial autocorrelation and coupling coordination degree (CCD) model to determine their interactive coercive relationships at the county level globally. Results showed that the global average UL was 0.0807, 0.0838, and 0.0857 in 2000, 2010, and 2020, respectively, with a continuously increasing trend. The global average HQ was 0.6186, 0.6133, and 0.6111 for 2000, 2010, and 2020, reflecting opposite declining trends. The Moran’s I of population urbanization and HQ in 2000, 2010, and 2020 globally remained negative but showed an increasing trend, with values of −0.189, −0.228, and −0.254, respectively, while those of economic urbanization and HQ and land urbanization and HQ also remained negative and exhibited a similar increasing trend. The spatial autocorrelations for UL and HQ in different dimensions indicated that deserts and plateaus functioned as catchment areas with low UL and HQ. The CCD between UL and HQ in each county globally ranged from 0 to 0.70, while CCD between land urbanization and HQ was the most optimal at 0–0.90. The CCD between population urbanization and HQ was similar to that of economic urbanization in terms of spatial distribution. Nevertheless, the CCD of land urbanization in HQ exhibited the greatest degree of coordination among the three urbanization dimensions during the study period. These findings provided important support for sustainable urbanization and ecosystem protection globally.
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