Catalytic Asymmetric Hydrogenation Of Imines Research Articles

Progress on the Catalytic Asymmetric Hydrogenation of Imines

Chiral amines are important synthetic intermediates in the preparation of many physiologically active compounds. Catalytic asymmetric hydrogenation of prochiral imines represents one of the most direct and convenient route to chiral amines and their derivatives. During the past two decades, significant progress has been made in the asymmetric hydrogenation of imines. Many highly enantioselective chiral catalysts have been disclosed, some new methods and strategies have been developed, and some challenging imines substrates have been efficiently hydrogenated in high enantioselectivities. Despite these achievements, catalytic asymmetric hydrogenation of imines still have challenges of low reactivity, narrow substrate scope, harsh hydrogenation conditions and difficulty in catalyst reuse. Therefore, development of new catalyst system with high reactivity and enantioselectivity as well as environmental friendship in the asymmetric hydrogenation of imines is of great interest. This review presents a brief overview on the progress in catalytic asymmetric hydrogenation of cyclic and acyclic imines.

ChemInform Abstract: Catalytic Asymmetric Hydrogenation of Imines. Use of Rhodium(I)/ Phosphine Complexes and Characterization of Rhodium(I)/Imine Complexes.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Iridium-Catalyzed Asymmetric Hydrogenation of N-Arylimines

Chiral amines and their derivatives are of great significance in pharmaceutical, biological, and synthetic chemistry. Examples can be found in many drugs or drug candidates, such as Cinacalcet and NPS R-568. Catalytic asymmetric hydrogenation of imines is a powerful method for obtaining enantiomerically pure amine products due to its high efficiency, low catalyst loading, and atom economy. The authors report that high enantiomeric excesses were obtained in the asymmetric hydrogenation of various N-arylimines catalyzed by an iridium complex containing a highly rigid, electron-donating P-chiral bisphospholane ligand, DuanPhos. High turnover numbers (TONs) were achieved under mild reaction conditions.

ChemInform Abstract: Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Kinetic and Mechanistic Investigations.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

ChemInform Abstract: Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Scope and Limitations.

AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Kinetic and Mechanistic Investigations

Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Kinetic and Mechanistic Investigations

Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Scope and Limitations

Catalytic Asymmetric Hydrogenation of Imines with a Chiral Titanocene Catalyst: Scope and Limitations

Catalytic asymmetric hydrogenation of imines. Use of rhodium(I)/phosphine complexes and characterization of rhodium(I)/imine complexes

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic asymmetric hydrogenation of imines. Use of rhodium(I)/phosphine complexes and characterization of rhodium(I)/imine complexesAdam G. Becalski, William R. Cullen, Michael D. Fryzuk, Brian R. James, Guo J. Kang, and Steven J. RettigCite this: Inorg. Chem. 1991, 30, 26, 5002–5008Publication Date (Print):December 1, 1991Publication History Published online1 May 2002Published inissue 1 December 1991https://doi.org/10.1021/ic00026a027RIGHTS & PERMISSIONSArticle Views652Altmetric-Citations105LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (844 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts