Catalytic Amount Of Copper Triflate Research Articles

Microwave-Assisted Domino Povarov-Type [4+2] Cycloaddition: A Rapid Access to 7-Phenyl-6H-chromeno[4,3-b]quinolines

AbstractA convenient, facile, and eco-friendly approach to synthesizing 7-phenyl-6H-chromeno[4,3-b]quinolines under microwave irradiation is presented. The current strategy enabled the synthesis of chromenoquinoline frameworks at 80 °C under shorter reaction times via intermolecular Schiff base formation followed by an intramolecular inverse demand hetero-Diels–Alder [4+2]-cycloaddition reaction by using a catalytic amount of copper triflate as the sole catalyst. Consequently, one C–N and two C–C bonds are constructed in a single pot, and a wide spread of 7-phenyl-6H-chromeno[4,3-b]quinolines have been synthesized with good functional group tolerance.

ChemInform Abstract: Intramolecular C—O/C—S Bond Insertion of α‐Diazoesters for the Synthesis of 2‐Aryl‐4H‐benzo[d][1,3]oxazine and 2‐Aryl‐4H‐benzo[d][1,3]thiazine Derivatives.

An intramolecular C–O insertion of 2-(2-arylamidophenyl)-2-diazoacetate has been achieved using a catalytic amount of copper triflate under mild conditions to produce 2-aryl-4H-benzo[d][1,3]oxazine-4-carboxylate in good yields. In addition, 2-diazo-2-(2-arylthioamidophenyl)acetate affords the corresponding 2-aryl-4H-benzo[d][1,3]thiazine derivatives under similar conditions. This is the first example of the synthesis of benzoxazines and benzothiazines from ortho-amidophenyl diazoacetate and ortho-thioamidophenyl diazoacetate, respectively.

Ambient gold-catalyzed O-vinylation of cyclic 1,3-diketone: A vinyl ether synthesis

Gold-catalyzed O-vinylation of cyclic 1,3-diketones has been achieved for the first time, which provides direct access to various vinyl ethers. A catalytic amount of copper triflate was identified as the significant additive in promoting this transformation. Both aromatic and aliphatic alkynes are suitable substrates with good to excellent yields.

Copper Triflate [Cu(OTf)2] is an Efficient and Mild Catalyst for the Silylation of α‐Hydroxyphosphonates to α‐Trimethylsilyloxyphosphonates with HMDS at Room Temperature.

AbstractFor Abstract see ChemInform Abstract in Full Text.

Copper triflate [Cu(OTf) 2] is an efficient and mild catalyst for the silylation of α-hydroxyphosphonates to α-trimethylsilyloxyphosphonates with HMDS at room temperature

A broad, adaptable, high yielding and convenient procedure for the fast conversion of various α-hydroxyphosphonates to α-trimethylsilyloxyphosphonates under mild conditions with HMDS in the presence of a catalytic amount of copper triflate is described. This procedure has also been applied successfully for the silylation of alcohols and phenols.

Catalytic Asymmetric Sulfimidation

A direct catalytic imidation of sulfides to sulfimides with [N-(p-tolylsulfonyl)imino]phenyliodinane (TsNIPh) using a catalytic amount of copper triflate (CuOTf) has been developed. The reaction pr...