Human activities may influence the distribution of naturally occurring radioactive materials in the environment. This therefore, cause for concern radiological, as human are exposed to these radioactive materials without their consent. This study hereby evaluate the radionuclide contents from natural and artificially occurring radionuclides in soil samples and farm produce in Enugu. Gamma-ray spectroscopy was used to determine the radioactivity concentration level of the environmental radionuclides such as 238U, 232Th, and 40K and manmade radionuclides in soil, cassava, and bitter leaf samples within studied locations in Enugu State, Nigeria. The mean activity concentration of the radionuclides detected in the samples were 1136.74±27.07, 1118.53±4.85, 196.104±0.02 Bqkg-1 for 40K, 41.66±0.04, 22.99±0.38, Bqkg-1 for 238U and 36.44±0.04, 15.89±0.07, 7.69±0.02 Bqkg-1for 232Th. 137Cs ranged from 3.07 ± 0.01 – 7.81 ± 0.03 Bqkg-1. The radioactivity levels and estimated radiological indices were higher than the recommended limits. The values confirmed the reports of different fora on the radiological hazards due to exposure to high radiation in the region assayed.