Climate change leads to a change in the distribution of insects, including blood-sucking. Mosquitoes are vectors for the transmission of dangerous anthropozoonotic diseases. Every year in the Kirov region up to 1100 diseases of natural focal infec-tions are registered. The temperate continental climate, abundant rainfall (500-680 mm per year) with a predominance of up to 70% in warm weather, the presence of forests and water bodies, swamped territory (40%) are favorable factors for the de-velopment of mosquitoes. On the territory of the region 25 species of mosquitoes of 5 genus are registered. The information on the fauna of mosquitoes on the territory of the Kirov region, the meteorological situation, and the epizoological situation on anthropozoonotic diseases, including dirofilariasis, were analyzed. Since 1942, the region has been unfavorable for tularemia with the last outbreak in 2012 near the floodplain of the Vyatka River. Since 2008, cases of human dirofilariasis with local-ization of the pathogen in the organs of vision have been recorded annually in the Kirov region. May – September is the most favorable for human infection, subject to the presence of a sick animal and a significant number of blood-sucking insects. Since 2013, cases of dirofilariasis of domestic and working dogs have been reported in the Kirov region, which indicates the presence of a local focus of dirofilariasis, in which mosquitoes are carriers of human and dog diseases. In dogs, the subcutane-ous (pathogen Dirofilaria repens) or cardiac (pathogen Dirofilaria immitis) forms of anthropozoonosis are recorded. The cardiac form of the disease is the most atypical. The diagnosis of dirofilariasis is made on the basis of anamnesis, clinical picture, laboratory tests for the detection of microfilariae in the blood.