Case Of Tuberculosis Verrucosa Cutis Research Articles

Tuberculosis Verrucosa cutis: A case report

TB verrucosa cutis is an inactive, verruca like plaque. Clinically it has classical description. Initially starts as a tiny symptom free warty papule that eventually headway to become a verrucous plaque with a rambling irregular border. Among the form of cutaneous tuberculosis. We report a case of Tuberculosis Verrucosa Cutis in a 54 year old male with a verrucous plaque with hyperpigmentation over the right great toe confirmed with clinical and histopathological features.

Zinc-responsive acral hyperkeratosis as a mimicker of cutaneous tuberculosis

Zinc-responsive acral hyperkeratosis is regarded as a novel entity masquerading numerous skin disorders, such as psoriasis, acral necrolytic erythema, and tuberculosis. Tuberculosis itself is a great imitator and so is its cutaneous form. Herein, we present the case of a female misdiagnosed as a case of tuberculosis verrucosa cutis due to clinical, biochemical, and histopathological features. The patient completed a full course of anti-tubercular therapy without an improvement and showed a dramatic response after a therapeutic trial of oral zinc. Thus, the patient was diagnosed as a case of zinc-responsive acral hyperkeratosis. In any form of acral hyperkeratotic lesions, zinc-responsive acral hyperkeratosis must be considered as a differential diagnosis.

Tuberculosis Verrucosa Cutis on the Buttocks: A Case Report

Introduction: Tuberculosis verrucosa cutis is a rare form of cutaneous tuberculosis and occurs commonly on the lower extremeties (hand, thighs and buttock). It is often missed as other cutaneous verrucosa dieases and the pathogens of cutaneous tuberculosis is difficult to find. We showed an unusual case of tuberculosis verrucosa cutis on both buttocks. Case presentation: A 54 Chinese male presented with 9-year history of asymptomatic verrucous lesions on bilateral buttocks. Lesions presented a well-defined plaque, verrucous lesion and yellow pus discharge on buttocks. The skin biopsy showed pseudoepitheliomatous hyperplasia of the epidermis and dermal granulomatous inflammation composed of epithelioid histiocytes and mixed inflammatory cells. The tuberculin test and the polymerase chain reaction for Mycobacterium tuberculosis were negative, but T-spot test were positive. the treatment of antituberculosis showed favourable effect. Finally, the diagnosis of tuberculosis verrucosa cuti was made. Discussion: Tuberculosis verrucosa cutis is easily confused with other verrucous diseases, such as verrucous porokeratosis, discoid lupus erythematosus hypertrophicus lichen planus, chromoblastomycosis. Diagnostic therapy is usually recommended for most of these diagnoses. Conclusion: A diagnosis of tuberculosis verrucosa cutis should be taken correctly based on the combination of clinical manifestions, histopathological characteristics, laboratory findings and diagnostic therapy. It is vital for dermatologists to be aware of verrucous lesions since a delay in diagnosis can lead to aggravate the disease, abuse of glucocorticoids.

Verrucous lesion over the foot: a diagnostic challenge

Infection with <em>Mycobacterium tuberculosis </em>or other very closely related strains, as well as the inflammatory reaction of the host, define the disease tuberculosis. Cutaneous tuberculosis constitutes a small proportion of extrapulmonary tuberculosis. Extensive, multifocal involvement of cutaneous tuberculosis is a rare manifestation. We report one such case of tuberculosis verrucosa cutis in a 24 year old immunocompetent male patient.

Tuberculosis verrucosa cutis: case report of a diagnostic challenge

<p class="abstract">Cutaneous tuberculosis occurs by either exogenous inoculation in a previously sensitized or non-immune host or endogenous spread from an internal focus by contiguous, hematogenous or lymphatic route. Inoculation occurs at sites of minor wounds or abrasions, sometimes from the patient’s own sputum. Cutaneous tuberculosis includes lupus vulgaris and tuberculosis verrucosa cutis (TVC) at one end and scrofuloderma and tuberculosis cutis orificialis at the other end with decrease in cell-mediated immunity across the spectrum. Of various cutaneous forms, we report a case of tuberculosis verrucosa cutis in a 14 year old girl who presented with a hyperpigmented verrucous plaque over foot since three years. Histopathological characteristics, GeneXpert and response to antitubercular therapy confirmed the diagnosis.</p><p class="abstract"> </p>

Chronic ulcerating genital herpes simplex virus infection: A diagnosis mislead by HIV infection

We report a case of chronic herpes simplex in a 27 year old lady presenting with a history of persistent verrucous ulcer in the natal cleft of nine months duration. The patient was diagnosed and treated initially as a case of Tuberculosis Verrucosa Cutis (TVC) based on the chronicity of the ulcer, negative HIV serological tests and histopathological findings. The diagnosis had to be revised as the lesion was increasing in size and the patient was not responding to treatment even after completing antituberculous treatment for six months. Repeat histopathological examination and immunohistochemistry showed DNA of herpes simplex. Based on this finding a repeat HIV serology was sent which was positive. The ulcer healed after a course of acyclovir. The case is being reported to highlight the importance of considering chronic herpes simplex infection in a case of chronic genital ulcer. In addition this case reminds us the nature of HIV infection to mislead the diagnosis by altering the natural course of the disease process.

Tuberculosis verrucosa cutis presenting as diffuse plantar keratoderma: An unusual sight

Tuberculosis verrucosa cutis (TVC) is a common cutaneous form of paucibacillary tuberculosis in an individual with moderate to high degree of immunity to Mycobacterium tuberculosis infection. Clinical appearance of TVC is mostly very typical with well-defined warty plaques presenting mostly on hands, knees, ankle, and buttocks; however several atypical morphology of the lesions have also been described. We hereby report a case of TVC, masquerading as asymptomatic diffuse keratoderma of left foot for nine months, in an otherwise healthy individual, obstructing easy diagnosis of cutaneous tuberculosis. Diagnosis was confirmed by histopathology.

Siğil Tanısı Konarak Tedavi Edilen Bir Tüberkülozis Verrükoza Kutis Olgusu

Tuberculosis is still among the major community health problems worldwide. The clinical diversity of cutaneous tuberculosis depends on the route of acquisition of infection and on the patient's immune system. Tuberculosis verrucosa cutis (TVC) results from an exogenous inoc - ulation of Mycobacterium tuberculosis, at sites prone to trauma. The lesion begins as a small, asymp - tomatic, indurated wart-like papule with a subtle inflammatory rim. It gradually enlarges in a serpiginous manner to form a firm reddish-brown verrucous plaque. The center of the lesion can become fluctuant and pus and keratinaceous debris may be expressed by slight pressure. We pre - sented a case of TVC, which was misdiagnosed as verruca vulgaris and had received prior treat - ments including topical salicylic acid, topical 5-fluorouracil, and several successive cryotherapy and cautery sessions.

Tuberculosis verrucosa cutis: A case report from a rural medical college of India

We report a case of tuberculosis verrucosa cutis (TBVC) on the foot that had been present for more than 6 years in a 42-year-old man. He had a positive Mantoux test and a normal chest radiograph. This case demonstrates the indolent nature of the disease. The diagnosis of TBVC should be based on history and evolution of the disease, cardinal morphological features and histopathological characteristics. Adequate therapeutic response may also helpful.

A case of tuberculosis verrucosa cutis - undiagnosed for 44 years and resulting in fixed-flexion deformity of the arm

Tuberculosis verrucosa cutis (TBVC) is a paucibacillary form of cutaneous tuberculosis caused by exogenous re-infection in previously sensitized individuals. Here, we report an unusual case of TBVC in a 53-year-old Chinese woman that had been present for 44 years and resulted in fixed-flexion deformity of her arm and functional disability. The diagnosis was made by a positive culture for Mycobacterium tuberculosis and she responded well to antituberculous therapy. To our knowledge, this is the first such case of TBVC reported in the English literature with sequelae of functional impairment of the arm.

Tuberculosis verrucosa cutis which Remained Undiagnosed for Forty-Three Years

An unusual case of tuberculosis verrucosa cutis of the left lower limb in a 65-year-old woman is reported. The disease, arising on the plantar aspect of the foot in 1950, was correctly diagnosed by culture of Mycobacterium tuberculosis complex from a skin biopsy only in 1993. A spectacular improvement of the cutaneous lesions was achieved using combined therapy with isoniazide, rifampicin, ethambutol and pyrazinamide.

Four cases of cutaneous tuberculosis

The incidence of the cutaneous tuberculosis has shown a steady decline over the past decades. This parallels the decreasing incidence of pulmonary tuberculosis. We experienced 5 cases of cutaneous tuberculosis from January 1990 to February 1991. We present herin 4 cases of cutaneous tuberculosis. They were 3 cases of vulgaris and 1 case of tuberculosis verrucosa cutis. Mantoux tests were done except one case and were reactive in all cases. Culture for Mycobactelium tuberculosis were done but Mycobacterium tuberculosis were not cultivated in the all cases. Histopathological findings showed tuberculoid granulomas in the dermis except one case and no acid fast bacilli were demonstrated on AFB stains.

An obscure case of ulceration of the nose in a child, simulating an epithelioma. (A probable case of tuberculosis verrucosa cutis)

An obscure case of ulceration of the nose in a child, simulating an epithelioma. (A probable case of tuberculosis verrucosa cutis)

A Case of Tuberculosis Verrucosa Cutis (Riehl and Paltauf's Disease)

A Case of Tuberculosis Verrucosa Cutis (Riehl and Paltauf's Disease)