Subungual Squamous Cell Carcinoma (SCC) is the most common malignancy affecting the nail bed. About 150 cases of subungual SCC have been reported in the literature. It usually involves the thumb, the index finger and only rarely, the toes. Subungual SCC runs an indolent course and may present with minimal symptoms. Diagnostic confusion emerges because many chronic lesions of the nail bed may be clinically similar to SCC. Although SCC of the nail bed is considered a low-grade malignancy, bone invasion and metastasis to the regional lymph nodes may occur. Herein, we reported a case of subungual toenail SCC with bone involvement and a 6-year delay between its appearance and diagnosis.