Case Of Pigmentation Research Articles

The Effectiveness of Using CO2 Fractional Laser and Mebo Burn Ointment Together in Treating Scars on the Face after Surgery.

This study aimed to investigate the efficacy and safety of CO2 fractional laser combined with Mebo burn ointment in treating facial postoperative scars. Sixty patients with facial postoperative scars in the department of plastic surgery of Sun Yat-sen Memorial Hospital from January 2020 to June 2022 were divided into a control group (30 cases) and a study group (30 cases). Both groups received CO2 fractional laser treatment, but the study group also received Mebo burn ointment application. The study found that both methods resulted in a significant decrease in Sawada score and a significant increase in Investigator Global Assessment score after treatment (P < 0.05), with the study group showing a more significant improvement and higher patient satisfaction (P < 0.05). All patients experienced varying degrees of bleeding, swelling, and erythema immediately after treatment, with two cases of pigmentation and two cases of persistent erythema in the control group, and one case of pigmentation and one case of persistent erythema in the study group. Adverse reactions were minimal, with the study group showing better tolerance. The study suggests that CO2 fractional laser combined with Mebo burn ointment is an effective and safe treatment for facial postoperative scars.

Efficacy of CO2 fractional laser combined with 5-aminolevulinic acid photodynamic therapy on refractory verruca plana

Objective To investigate the safety and efficacy of CO2 fractional laser combined with 5-aminolevulinic acid (ALA)-mediated photodynamic therapy (ALA-PDT) for the treatment of refractory flat wart. Methods The 80 patients with facial flat wart were randomly divided into observation group (40 cases) and control group (40 cases). The observation group was treated with CO2 fractional laser combined with 5-ALA-PDT, and the control group was treated with 5-ALA-PDT only. Those with residual lesions after the first treatment were treated with the second or third times. The interval duration between treatments was 2 weeks. The efficacy and the adverse reaction were evaluated after the 2-week, 4-week and 6-month after the last treatment. Results Compared with prior treatment, the facial lesions achieved complete response and improvement. The total effective rate of the observation group were 90.0% (36/40) and 72.5% (29/40) for the control group, the difference was statistically significant (P<0.05). There were 2 cases of pigmentation occurred in observation group and 3 cases in control group. The complications including infection and hypertrophic scar were seldom occurred in the two groups. Conclusions The safety and efficacy of CO2 fractional laser combined with ALA-PDT are better than that with ALA-PDT only in the treatment of refractory flat wart. Key words: Flat wart; CO2 fractional laser; 5-aminolevulinic acid (ALA)-mediated photodynamic therapy

A Case of Pigmentation and Subcutaneous Induration of Hips due to Transcatheter Arterial Infusion-Chemotherapy

A Case of Pigmentation and Subcutaneous Induration of Hips due to Transcatheter Arterial Infusion-Chemotherapy

金銀パラジウム合金による粘膜着色の１例

金銀パラジウム合金による粘膜着色の１例

Surgical Management of Idiopathic Epiretinal Membranes

The authors reviewed 33 consecutive cases of idiopathic epiretinal membranes removed by vitreous surgical techniques. Visual acuity improved in 79% of surgically treated eyes. In uncomplicated cases, a 47% gain in visual acuity was achieved. Of those eyes that had improved visual acuity post-operatively, 82.5% of the final visual acuity returned by four to eight weeks postoperatively. Eyes with opaque membranes had visual acuity results no worse than those with translucent membranes. Eyes with no pre-operative cystoid edema had better visual acuity results than eyes with cystoid macular edema (CME), although no statistically significant difference was shown. Surgical removal of membranes decreased fluorescein dye leakage in 30% of eyes; while no change in post-operative leakage was noted in 60%, one eye had increased CME post-operatively. Complications included development of nuclear sclerotic cataract, retinal breaks, retinal detachment, and one case of pigment epithelial/retinal burn from the endoilluminator, residual and recurrent membrane formation, and anterior ischemic optic neuropathy.

Complete Congenital Pigmentation of the Optic Disc

Congenital pigmentation of the optic disc is of comparatively rare occurrence, and references to it in the literature are infrequent. While several types of pigmentation have been recognized, few cases of entire pigmentation of the papilla have been reported. Sobanski observed a case of complete pigmentation of the disc. From a survey of the literature he found only two cases which he believed to be similar. Hirschberg described a color of uniform dark slate gray upon which the retinal vessels were scarcely visible. Forster referred to the pigmentation of the disc as shades of dark smoked glasses. These men were of the opinion that the condition was a congenital anomaly—a melanosis of the optic nerve. Juler and Mann referred to three main types: (1) Dense isolated plaques which might occupy a sector of the disc and extend into the surrounding retina. These might appear black with otherwise normal eyes, or might be confined to the physiologic cup and be brownish gray in color. (2) As linear markings, commonly found on the temporal side near the disc edge, and curved concentrically with it. (3) As lacelike pigmented veils, closely associated with the blood vessels. Thomson and Ballantyne reported a case of pigmented colobomata of the optic disc in a myopic patient in whom both discs presented an unusual picture. The appearance of the right disc was as if a wedge had been cut out of its outer and lower portion. This colobomalike wedge contained a network of brown pigment situated below the level of the disc surface. In the left eye, the pigmentation was similar, but instead of extending to the very edge of the disc it was separated from it by a narrow band of nerve tissue. Reese mentioned small, isolated, clearly demarcated dots of jet-black pigment located superficially in the nerve-fiber layer of the disc. Small pigmented spots do not appear to be rare. Ogawa observed seven cases of this type in which the pigment was distributed indiscriminately over the disc. He believed that these spots are not necessarily associated with any other abnormal pigmentation of the eyeball and that they do not interfere with vision. Of an allied nature are rare instances of pigmentation of the entire disc. Coats, in describing two classes of congenital pigmentation, was of the opinion that the isolated black spots are due to a pigmented lamina cribrosa. His second group comprised pigmented craterlike holes in the disc. The same author advanced the hypothesis that in certain groups of congenital anomalies, any part of the secondary vesicle and optic stalk may differentiate, perfectly or imperfectly, into any type of tissue normally from the optic outgrowth; for example, pigmented epithelium, unpigmented epithelium, retina, or neuroglia. These might occur in the following situations: (1) on the iris, (2) on the ciliary body, (3) on the retina, and (4) on the optic nerve. Consequently, it should be possible to find any of these four kinds of tissue in the optic nerve or in the eye proper. From these observations the idea may be advanced that, in congenitally abnormal eyes, a part of one layer of the secondary optic vesicle can develop into structures which normally originate in the other, or in a different part of the same eye. Roll described a case of congenital pigmentation of the optic disc complicated with retinitis diabetica. The vision was reduced as a result of the macular exu-

Note on the pigmentation of Lernaeopoda (Copepoda)

I am greatly indebted to Prof. O. Nybelin of Göteborg for the loan of two specimens of female Lernaeopoda scyllicola Leigh-Sharpe, 1915 taken by him from the extra-cloacal region of two Scylliorhinus canicula (L.) during the first fortnight of September 1938 at Roscoff which show peculiar cases of pigmentation (Fig. 1).

A PECULIAR DISCOLORATION OF THE SKIN

In 1922, I1reported two cases of pigmentation of the face as the result of using cosmetic containing calomel. At the time, this seemed a rather rare phenomenon, and was thought to be dependent on a personal chemical peculiarity of the perspiration. Subsequent experience has demonstrated that such a peculiarity is not especially rare, if we may thus explain the pigmentation. Within the last year, I have seen thirteen more cases, in all of which the distribution of the discoloration was very striking and readily recognizable. It is not uncommon to have one of the youngest dermatologic assistants make the diagnosis. Curiously enough, however, the general clinician rarely suspects the true nature of the pigmentation, but looks on it as an early addisonian pigmentation, an evidence of fatigue attendant on nervous exhaustion, or cardiac, hepatic or other chronic diseases, or disregards it entirely. When it was first recognized that

Sections of Skin. from Case of Pigmentation (Argyria)

Sections of Skin. from Case of Pigmentation (Argyria)

Case of Pigmentation (? Addison's Disease)

Case of Pigmentation (? Addison's Disease)

Case of Pigmentation of the Face

Case of Pigmentation of the Face

A Case of Pigmentation with Enlarged Spleen and Leucopenia.? Splenic Anaemia

A Case of Pigmentation with Enlarged Spleen and Leucopenia.? Splenic Anaemia