Case Of Osteoblastoma Research Articles

Ethmoid Osteoblastoma: A Case Report and Pooled Analysis of Cases.

Osteoblastoma is a typically noncancerous bone tumor commonly found in the spine and long bones of the arms and legs. It is exceedingly rare for this tumor to occur in the paranasal sinuses. We present a case of osteoblastoma in a 13-year-old boy affecting the ethmoid sinus, which manifested as exophthalmos. A computed tomography scan revealed an expansive lesion in the right ethmoid sinus, causing compression and displacement of the orbital contents to the right. The lesion exhibited a mix of ground glass opacity and dense bone. On magnetic resonance imaging, the less dense areas of the tumor showed strong enhancement, while the densely sclerotic regions appeared as signal voids on all imaging sequences. A combined transorbital and transnasal approach was performed to remove the tumor. Histologically, the tumor consisted expansile growth surrounded by a sclerotic rim of inter-anastomosing trabeculae of woven bone set within loose edematous fibrovascular stroma. This case highlights the unusual occurrence of osteoblastoma in the ethmoid sinus, a location seldom associated with this type of tumor, and adds to the existing literature on this topic and offers a new surgical approach to managing this entity.

AGGRESSIVE OSTEOBLASTOMA OF THE SCAPHOID – THE DIAGNOSTIC CHALLENGE: A RARE CLINICAL CASE

Osteoblastoma is an infrequent benign tumor, rarely found in the hand. We present a case of osteoblastoma of the scaphoid in a 58-year-old adult male patient, its diagnostic challenge, and his treatment pathway from curettage and autologous bone graft until scaphoidectomy and four-corner fusion. The tumor showed an aggressive behavior and local destruction in an unusual location. It appeared in a patient outside the expected age range for this specific tumor, rendering a correct diagnosis extremely difficult to achieve. We pretend to emphasize its treatment evolution and highlight the importance of follow-up and surveillance of these tumor lesions.

Osteoblastoma of the temporal bone – A familiar tumour at an uncommon site

Osteoblastoma is a benign bone tumour arising from the non-odontogenic epithelium. This tumour predominantly affects the vertebral column and long tubular bones such as the femur and tibia. Herein, we report a case of Osteoblastoma affecting temporal bone. Radiologically, it was thought to be an intraosseous meningioma, hemangioma, or eosinophilic granuloma. Histopathological examination of the tumour showed woven bone arranged in sheets and micro trabecular array, rimmed by a single layer of osteoblast, surrounded by lamellar bone. Intertrabecular spaces were composed of richly vascular fibrotic stroma, consistent with the diagnosis of osteoblastoma.

A rare case of osteoblastoma of the orbit

A rare case of osteoblastoma of the orbit

A Rare Case of Osteoblastoma of Calcaneum with Secondary Aneurysmal Cyst Like Changes and its Management- A Case Report

Background: Osteoblastoma is a rare bone forming neoplasm and it is very rare to present with secondary cystic changes that too in the heel bone. The incidence is <0.6 % among all and its prevalence is yet to be reported in our population. owing to its rare presentation the early diagnosis of Osteoblastoma of calcaneum with secondary aneurysmal cyst like changes are difficult and hence affects the outcome. Material: In this report we detailed the diagnostic methods and surgical management of osteoblastoma of calcaneum associated with secondary aneurysmal cyst like changes in a 12year old boy with 2 year follow up. Result: It shown that the expansile lytic lesion was healed at appropriate time period and ankle & subtalar range of movements were satisfactory with no limitation in inversion and eversion. Conclusion: Benign expansile bone tumors in heel bone are difficult to find in the literature. This study addresses the diagnostic modality, proper surgical management in terms of approach and using sandwich bone grafting technique to improve the long term functional outcome. Keywords: Osteoblastoma of calcaneum, Secondary aneurysmal cyst like changes, Curettage and bone grafting.

A Rare Case of Osteoblastoma of Calcaneum with Secondary Aneurysmal Cyst Like Changes and its Management- A Case Report

Background: Osteoblastoma is a rare bone forming neoplasm and it is very rare to present with secondary cystic changes that too in the heel bone. The incidence is <0.6 % among all and its prevalence is yet to be reported in our population. owing to its rare presentation the early diagnosis of Osteoblastoma of calcaneum with secondary aneurysmal cyst like changes are difficult and hence affects the outcome. Material: In this report we detailed the diagnostic methods and surgical management of osteoblastoma of calcaneum associated with secondary aneurysmal cyst like changes in a 12year old boy with 2 year follow up. Result: It shown that the expansile lytic lesion was healed at appropriate time period and ankle & subtalar range of movements were satisfactory with no limitation in inversion and eversion. Conclusion: Benign expansile bone tumors in heel bone are difficult to find in the literature. This study addresses the diagnostic modality, proper surgical management in terms of approach and using sandwich bone grafting technique to improve the long term functional outcome. Keywords: Osteoblastoma of calcaneum, Secondary aneurysmal cyst like changes, Curettage and bone grafting.

A rare case of osteoblastoma of calcaneum with secondary aneurysmal cyst like changes and its management: A case report

A rare case of osteoblastoma of calcaneum with secondary aneurysmal cyst like changes and its management: A case report

Osteoblastoma of the Capitate Bone: Case Report.

Carpal bone tumors must be investigated in clinical cases of chronic wrist pain with no previous trauma. Intraosseous ganglion, enchondroma, osteoid osteoma, and, less commonly, osteoblastoma are potential causes of osteolytic lesions affecting the carpal bones. In most cases, the clinical presentation alone is not enough to differentiate such lesions. Knowledge of certain characteristics, including the radiological and histopathological aspects of each of these tumors, is critical in order to make the differential diagnosis. We present a rare case of osteoblastoma of the capitate bone and review the literature on the subject.

An unusual case of osteoblastoma in shaft of fibula: Case report

Background: Osteoblastoma and osteoid osteoma are rare, benign, bone forming tumours. This is a rare case of osteoblastoma in shaft of a long bone, in an unusual location, causing a therapeutic dilemma.Aims & Objectives: Osteoblastoma and osteoid osteoma are closely related lesions with similar histological patterns and indistinguishable radiographic features. This case was studied to understand the similarities and differentiating features of the two. Methods: Here was a case of 18 years old male patient with history of bony swelling and pain in his right leg which relived with a dose of Aspirin. After thorough examination plain radiographs and CT scan of the part was done. Surgical excision of the lesion was done and sent for histopathology examination. Patient was adequately treated and followed up at 1,3,12 & 18 months post operatively to assess the involved site and evidence of recurrence. Result: Plain radiographs and CT scan of the part involved provisionally diagnosed the lesion as osteoid osteoma. Histopathology examination found features suggestive of osteoid osteoma and a diagnosis of osteoblastoma was given, considering the size of the nidus. Patient was followed up at 1,3,12 & 18 months post operatively and there was no evidence of recurrence. Conclusion: Osteoblastoma and osteoid osteoma were classified as variants of single tumour type based on a number of shared histological and radiographic features. Most significant difference between the two lesions is the size of the nidus. Thus, there may be transitional zone of uncertainty in establishing the correct diagnosis. Osteoid osteoma must be considered a differential diagnosis when the lesions are large and in unusual sites like long bones.

AN Unusual case of osteoblastoma in an elderly female: A case report and a review

AN Unusual case of osteoblastoma in an elderly female: A case report and a review

OSTEOBLASTOMA VS OSTEOID OSTEOMA: 2 CASE REPORTS

<h3>Clinical Presentation</h3> Case 1: A 17-year-old male presented 3 months –after third molar extraction with progressively worsening pain in the lower left extraction site. Clinical examination was unremarkable. Computed tomography (CT) showed a 12 × 10 × 11 mm, well-demarcated, circular, nonexpansile, mixed-density lesion with a sclerotic border and surrounded by a radiolucent rim. Lingual cortical bone defect was noted. Case 2: A 37-year-old male presented with progressively worsening pain in the left posterior mandible and preauricular area. CT showed a 16 × 21 mm well-defined, expansile, mixed-density lesion with a soft tissue capsule, which was surrounded by a sclerotic band. Unusual features included buccal/lingual expansion, new bone apposition, and soft tissue edema in the masseter muscle. Clinically, the site was significant for swelling. <h3>Differential Diagnosis</h3> Given the radiographic findings and the presence of pain, osteoblastoma and osteoid osteoma were considered in the differential diagnoses in both cases. Case 1 included cementoblastoma and foreign body reaction. In case 2, osteosarcoma was considered because of the apparent expansion. Because of the lesion size, osteoid osteoma was considered unlikely. <h3>Diagnosis and Management</h3> Both patients were initially managed pain with nonsteroidal anti-inflammatory drugs (NSAIDs), but the symptoms continued to worsen. Case 1 was treated with enucleation, curettage, and extraction of tooth #18. Case 2 was treated with excisional biopsy and extraction of tooth #17. Histologic reports rendered a final diagnosis of osteoblastoma in both cases. <h3>Discussion</h3> Osteoblastoma is rare, especially in the maxillofacial region. We present 2 unusual and distinct cases of osteoblastoma. In case 1, there was large cortical perforation with no expansion, whereas in case 2, the lesion was expansile with no perforation. To the best of our knowledge, soft tissue edema and new bone apposition, as seen in case 2, have not been reported previously.

Recurrent lumbar-origin osteoblastoma treated with multiple surgery and carbon ion radiotherapy: a case report

BackgroundAlthough osteoblastoma is an uncommon benign bone tumor, it sometimes behaves in a locally aggressive fashion. We herein report a case of recurrent lumbar spine osteoblastoma that was treated by repeated surgery and carbon ion radiotherapy.Case presentationA 13-year-old Japanese girl presented with left side lumbar pain. Computed tomography and magnetic resonance imaging of the lumbar spine demonstrated a tumorous lesion in the left side pedicle of L4. Although gross total resection of the mass, including the nidus, was performed in the initial surgery, recurrence was observed repeatedly in the short term and the pathological diagnosis of all of the resected tumors was conventional osteoblastoma. We finally performed carbon ion radiotherapy after the patient’s 3rd palliative operation, and achieved a good outcome. No further recurrence has been observed in 10 years of follow-up.ConclusionWe performed carbon ion radiotherapy for a case of recurrent spinal osteoblastoma and achieved a good outcome without recurrence at 10 years after carbon ion radiotherapy treatment. To the best of our knowledge, this is the first case of osteoblastoma that was treated with carbon ion radiotherapy after multiple surgeries.

A rare case of osteoblastoma from medieval Tuscany

A rare case of osteoblastoma from medieval Tuscany

A rare case of osteoblastoma combined with severe scoliosis deformity, coronal and sagittal imbalance

BackgroundOsteoblastoma is a rare and benign tumor which requires early diagnosis and surgical excision. Scoliosis is a common presentation following osteoblastoma. It is considered due to pain-provoked muscle spasm on the side of the lesion. Few researches about osteoblastoma combined with severe scoliosis have been reported.Case presentationA 14-year-old girl presents with progressive scoliosis deformity for 3 years, with gradually appeared low back pain and numbness of left leg. Radiographic results showed osteoblastic mass at the left side of L3-L4 with severe scoliosis deformity, pelvic obliquity and spinal imbalance. The patient underwent posterior tumor excision, spinal decompression, scoliosis correction, spinal fusion with auto-graft and instrumentation from T8-S1. The mass was found to be osteoblastoma. The patient had a full neurological recovery with no aggravate of scoliosis or spinal imbalance during the follow-up.ConclusionsThis case emphasizes the importance of early diagnosis and surgical treatment of osteoblastoma. Early surgical excision will not only prevent neurological deficit but also the progression of scoliosis. Atypical scoliosis presence without pain requires carefully examination of whether a tumor exists.

A Case of Osteoblastoma Accompanied with Concha Bullosa of the Inferior Turbinate

Osteoblastoma is a rare benign tumor, representing less than 1% of all bone tumors. Most cases occur in the vertebrae and in the long bones. Intranasal or paranasal osteoblastoma is particularly rare and only one case of osteoblastoma in the inferior turbinate has been reported in the world literature. Treatment is intralesional curettage or en bloc resection. Since the tumor is benign, conservative surgery is curative in about 80-90% of the cases. Concha bullosa is an abnormal pneumatization of the intranasal turbinates and inferior concha bullosa is a very rare condition. We report an unusual case of osteoblastoma occurring together with inferior concha bullosa. The tumor and inferior concha bullosa were removed by endoscopic submucosal inferior turbinoplasty, with favorable results. Related articles are reviewed and brief discussions are presented in regards to the case findings. Key words: Concha bullosa ㆍ Inferior turbinate ㆍ Osteoblastoma

下顎骨に生じた骨芽細胞腫の1例

下顎骨に生じた骨芽細胞腫の1例

Management Strategy of Osteoblastomas Localized in the Occipitocervical Junction

The aim of this article was to analyze extracted patient data from the literature and highlight the best treatment options and survival outcomes for osteoblastomas in the occipitocervical region. A systematic literature search method was used to select articles containing information about the demographic features, tumor location, treatment characteristics, adjuvant therapies, and follow-up time. From 25 articles, 31 cases of osteoblastoma in the occipitocervical junction were selected for analysis. Average patient age was 17 years (range, 5-57 years); there were 21 male (67%) and 10 female (33%) patients. All patients had cervical pain as the presenting symptom. Other symptoms included torticollis (0.13%) and sensory or motor neurologic deficits (0.16%). The average follow-up time was 41 months, and the local recurrence rate was 0.125%. Recommendations of each article are categorized and discussed in detail. Osteoblastoma is a rare entity in the occipitocervical region, so treatment experiences are limited and mostly based on case reports. To determine the best treatment for these lesions, osteoblastomas should be staged using the Enneking staging system; different methods may be recommended for different stages, and the feasibility of fusion depends on the remaining amount of bony structures and joints. Additional adjuvant therapies may be recommended only in special cases.

Osteoblastoma of the Capitate Bone

Osteoblastoma is a bone-producing tumor closely related to osteoid osteoma [1–3]. Osteoblastoma usually involves the vertebral columns, pelvis and long bones; however, there are sporadic reports of wrist and hand involvement [4–22]. The uncommon occurrence of an osteoblastoma diagnosis means that it is rarely considered in differential diagnosis of hand tumors. Osteoblastoma in the carpal bones is usually reported in the scaphoid bone [6, 7, 9, 11, 15, 20, 21]. Murray et al. in their review about primary neoplasms of carpal bones found only one case of osteoblastoma involving the capitates bone; however, they did not present any further detail about the case [9]. This report presents a singular case of osteoblastoma involving the capitate bone.

Immunohistochemical expression of β-catenin in osteoblastoma and osteosarcoma

Introduction Osteosarcoma (OS) is the most prevalent primary malignant tumor of bone in adolescents. Osteoblastoma (OB) is a rare benign bone tumor with a few aggressive variants. The differentiation between OS (low-grade types) OB (especially aggressive variant) by microscopic examination alone can be difficult, especially when using small biopsy specimens. Recently, the Wnt/β-catenin pathway has emerged as an essential pathway in bone development. Aim The aim of this study was to evaluate the immunohistochemical expression of β-catenin in OS and OB and its possible role in tumor diagnosis and prognosis. Materials and methods In total, 28 biopsies of OS (18 male and 10 female) and 12 cases of OB (10 male and two female) were examined for β-catenin immunostaining. Results β-Catenin showed cytoplasmic expression in 5/28 (17.9%) OS samples and in 8/12 (66.7%) OB samples, with a statistically significant relationship (P>0.008). Conclusion β-Catenin is a valuable tumor marker to differentiate between OS and OB, especially the aggressive variant.

Midline skull tumors

Introduction: Variety of tumors could involve the skull; however, very few may occur over the midline. Some may affect venous blood flow of superior sagittal sinus. Few challenging cases are presented Material: 1-Rare case of osteoblastoma over the torcula, (headache, visual symptoms, papilledema, VI nerve palsy). 2- Rare case of metastatic liposarcoma involving midsagital sinus, partially occluding it (headache and visual blurring). 3- A huge atypical (grade2) meningioma over the vertex Method: Case #1, the tumor over the venous confluences (torcula) was removed easily, without any complications. Complete resolution of symptoms Case #2, complete en-block resection of tumor, with sacrifice of mid-sagittal portion of sinus, without any neurological sequellae. Case #3, subtotal resection, followed by radiotherapy.Discussion &amp;Conclusion: Anterior 3rd of sagital sinus could be sacrificed (if necessary), without major consequences. However, whenever mid or posterior portion of the sinus is involved, interruption of venous flow could pose very serious complications. Occasionally, chronic compression of sinus may force increasing collateral venous return, in which case one may attempt a complete resection of the lesion, with sacrifice of part of the sinus, as in our second case. In the region of torcula, however, one should be very careful not to damage it