Case Of Keratosis Lichenoides Chronica Research Articles

Keratosis lichenoides chronica

Keratosis lichenoides chronica (KLC) is a rare chronic disorder of keratinization, characterized by the progressive development of erythematosquamous plaques and violaceous lichenoid hyperkeratotic papules, nodules and ridges. These lesions are most commonly found in a symmetrical distribution on the trunk and extremities and display a unique linear and/or reticulate pattern. The etiology of KLC remains unknown and the eruptions tend to be refractory to treatment. We describe a case of keratosis lichenoides chronica that improved with systemic retinoids.

Kératose lichénoïde striée et exposition prolongée aux infrarouges

We report a case of keratosis lichenoides chronica and prolonged exposure to a source of heat (infrared radiation). A 35 year-old man was examined for a symmetric and reticulate dermatosis on the abdomen, the interior of arms and lower extremities. The lesions had progressed over several months. They were characterized by hyperpigmentation, erythematous, bullous and squamous papules. These lesions were associated with those of the scalp, evoking seborrheic dermatitis. The patient was exposed to a source of heat with an electric radiator on his bare chest everyday. The skin biopsy showed a lichenoid reaction. All these elements allowed to put the diagnosis of keratosis lichenoides chronica, probably actived by the infrared light. Keratosis lichenoides chronica is a rare acquired dermatosis of the young adult. Its physiopathology remains elusive. This dermatosis is characterized by keratosic violaceous lichenoid papules distributed symmetrically. The eruption is usually asymptomatic. The histological examination indicates a lichenoid reaction. The progression is chronic and the disease is very resistant to therapy. Keratosis lichenoides chronica has never been described as being able to be induced by Koebner's phenomenon. In the literature, two cases of erythema ab igne were associated with lichen planus. For some authors, keratosis lichenoides chronica is an entity itself, for others it would be related to lichen planus. These arguments enabled us to diagnose keratosis lichenoides chronica probably activated by the infrared light.

Keratosis lichenoides chronica: a variant of lichen planus.

In order to establish a possible relationship between keratosis lichenoides chronica (KLC) and lichen planus (LP), we performed a comparative study which included routine histologic examination, electron microscopy, and direct immunohistochemical studies from one case of KLC and several patients with LP. Our findings demonstrate that KLC and LP share many similarities; their differences are mostly quantitative. In KLC, the findings are more prominent; we therefore conclude that KLC is at one end of the spectrum of LP.

Keratosis lichenoides chronica: Response to topical calcipotriol

Keratosis lichenoides chronica is a rare, chronic, progressive dermatosis, considered by some investigators to be a variant of lichen planus. The disease is resistant to treatment. We report a case of keratosis lichenoides chronica treated successfully with topical calcipotriol (Dovonex).

Keratosis lichenoides chronica: The Centenary of Another Kaposi’s Disease

In 1895, Kaposi used the term 'lichen ruber acuminatus verrucosus et reticularis' to describe the case of a 27-year-old woman with a linear, warty lichenoid eruption. We have reviewed the literature and found 50 cases, of which only 40 had common features reminiscent of the original description of Kaposi. These 'authentic' cases of keratosis lichenoides chronica (KLC) showed strong clinical and histological similarity, a uniformity indicating that KLC is an entity and is distinct from lichen planus. KLC may be associated with internal diseases such as glomerulonephritis and lymphoproliferative disorders.

Keratosis lichenoides chronica: Report of a case

We are reporting a case of keratosis lichenoides chronica. This is a chronic dermatosis characterized by seborrheic dermatitis-like facial eruption and purplish papulonodular lesions of the extremities. These lesions sometimes show linear configuration. Histologic changes include features of a chronic and lichenified dermatitis and lichen planus.

Keratosis lichenoides chronica

Description of a case of keratosis lichenoides chronica with presence of blisters. Histologically, the initial lesion seems to be localized at the dermo-epidermal junction. The vessels of the upper dermis are altered.