Case Of Juvenile Ossifying Fibroma Research Articles

Juvenile Primary Ossifying Fibroma of Maxillary Sinus: A Case Report and Review of the Literature

Fibro-osseous lesions (FOLs) are a group of benign bone disorders, defined by the replacement of functional bone by fibrous connective tissue matrices. Our case report delves into the presentation of a specific FOL, namely the juvenile ossifying fibroma (JOF). This disease’s rare occurrence in a clinical setup makes documentation of such presentations vital to otorhinolaryngologists across the globe. Our article highlights the presentation of such a case of JOF in a 15-year-old male child from Pakistan. We discuss differentials, our process towards reaching a diagnosis via biopsy, and the disease’s resolution via surgical excision. Due to JOF mimicking a plethora of similar otorhinolaryngology-adjacent diseases, our article wishes to provide insight with regards to approaching patients with relevant presenting complaints, eliminating differentials, and deciding on a particular treatment regimen.

Juvenile (aggressive) ossifying fibroma: A rare clinical entity

Juvenile ossifying fibroma (JOF) is a benign, osteogenic, potentially aggressive neoplasm of the craniofacial bones. It is very similar in presentation to conventional ossifying fibroma although more aggressive and of earlier onset. Complete removal of the tumor at the earliest with a long-term follow-up is recommended owing to its high rate of recurrence of 30–56%. The authors present a case of JOF in an 11-year-old boy, along with a brief review of nomenclature, origin and clinical presentation of these rather uncommon lesions. It very often mimics a malignancy in its clinical presentation due to rapid growth and young age. Histopathological examination is thus very critical to confirm the diagnosis.

Juvenile Ossifying Fibroma of Paranasal Sinuses—Do We Need to Be Radical in Surgery?

Juvenile ossifying fibroma (JOF) is an uncommon, benign, bone-forming neoplasm seen in the craniofacial bones. It is distinguished from other fibro-osseous lesions primarily by its age at onset, clinical presentation, and potential aggressive behavior. Occasionally JOF may grow aggressively and extend to involve the orbits and skull base, resulting in serious cosmetic and functional problems. A radical surgery is not advisable in a pediatric age group. We describe a case of JOF of the maxilla removed by sublabial approach conservatively, but completely without compromising the aesthetic looks of the young patient.

Juvenile Trabecular And Psammomatoid Variant Of Ossifying Fibroma Of The Maxilla With Secondary Aneurysmal Bone Cyst.

Juvenile ossifying fibroma (JOF) is a locally aggressive benign lesion most commonly involving the facial bones. It has been classified as psammomatoid (Ps JOF) and trabecular (Tr JOF) based on histological criteria. Both the variants are known to have overlapping histopathological features with other variants of ossifying fibromas. Complete surgical excision is the treatment of choice. Here, a case of JOF with histopathological features of both psammomatoid and trabecular pattern with secondary aneurysmal bone cyst is presented along with clinical and radiological findings.