Case Of Central Odontogenic Fibroma Research Articles

A Rare Case of Central Odontogenic Fibroma of the Mandible

A Rare Case of Central Odontogenic Fibroma of the Mandible

Central Odontogenic Fibroma of Mandible: A Rare Case Report with Review of Literature

Central Odontogenic fibroma is an extremely rare neoplasm that develops from mature fibrous connective tissue with varying amounts of odontogenic epithelium. Its incidence is 0.1% of all odontogenic tumors. It occurs with equal frequency in the maxilla and mandible with female predominance. Two clinical variants are known: intraosseous or central and extraosseous or peripheral odontogenic fibroma. It is radiolucent and may present as a well-defined unilocular or multilocular slow-growing mass. Here we reported a case of central odontogenic fibroma in 44-year-old male in the posterior region of left mandible. We present this case because of its rarity.

Central odontogenic fibroma: A case report with histopathological differential diagnosis

Odontogenic fibromas are one of the infrequent neoplasms seen in the oral cavity with a prevalence rate of 0.1%. They are derived from the odontogenic ectomesenchyme with diverse histopathology. Found most commonly in the anterior maxillary region, these lesions have a female predilection. Odontogenic fibromas are treated by enucleation followed by extensive curettage. The cognizance of the unique clinical, radiographic, and histopathological features is very important to conclude a confirmatory diagnosis. This article reviews a case of central odontogenic fibroma which presented in our department and also elucidates the diagnostic criteria of the same.

A recurrent case of central odontogenic fibroma in maxilla showing root resorption: a case report

Objective: The aim of this report is present an aggressive recurrent case of central odontogenic fibroma (COF) with tooth resorption in anterior maxilla, and discuss both events based on literature. Case description: A 29-year-old woman was referred for examination of a non-swelling intraosseous lesion detected by routine radiographic exams for orthodontic planning. Panoramic exam revealed a well-defined multiloculated radiolucency in the right anterior maxilla. Periapical radiography highlighted dental resorption of canine and first premolar. After the incisional biopsy the COF diagnosis was confirmed. Tumor was removed by enucleation. Recurrence was detected three years later and the lesion was removed together with involved teeth. No indication of recurrence has been observed in the past eight years. Conclusion: COF is a benign tumor and can be aggressive. Recurrence and root resorption simultaneously are rare features reported in literature. The treatment must include tooth removal and curettage. Prognosis is good and follow-up is important.

自家腸骨海綿骨細片移植による即時顎堤再建後にインプラント治療を施行した歯原性線維腫の1例

自家腸骨海綿骨細片移植による即時顎堤再建後にインプラント治療を施行した歯原性線維腫の1例

A Case of Central Odontogenic Fibroma of the Mandible

A Case of Central Odontogenic Fibroma of the Mandible

Central odontogenic fibroma: Report of case with immunohistochemical study

To report a case of central odontogenic fibroma (COF) with immunohistochemical study. We describe a case of epithelium-rich type of COF in the posterior region of the mandible of a 39-year-old woman. Immunohistochemical examination showed the odontogenic epithelium to be positive for high-molecular-weight cytokeratins, vimentin and CD99, and negative for CAM5.2. The stroma contained some myofibroblasts and many fibroblast-like cells positive for CD99. Our immunohistochemical findings, and especially the positive expression of vimentin from the epithelial cells of COF suggests that these cells are primordial. Last but not least, the presence of a relative small number of myofibroblasts in the stroma justifies the non-aggressive behavior of the neoplasm and supports that a part of stromal collagen of COF is produced by these cells.

A central odontogenic fibroma mimicking a dentigerous cyst associated with an impacted mandibular third molar—Immunohistological study and review of literature

Odontogenic fibroma is a relatively rare and benign odontogenic tumor of mesodermal dental sac or periodontal ligament origin. We report a case of central odontogenic fibroma (COF) mimicking a dentigerous cyst associated with an impacted left mandibular third molar, together with immunohistological studies and a literature review. Including present case, a total of 24 cases of COF have been investigated immunohistologically to determine the origin of epithelial components or fibroblasts found in the parenchyma of the tumors. In the present case, the epithelial components were strongly positive for cytokeratin (CK AE1/AE3), and the fibroblasts were positive for vimentin. The site around the hard tissue was strongly stained by vimentin. Surgical findings indicated that the tumor extended to the periodontal ligament, suggesting that the tumor possibly originated in the periodontal ligament. A review of the literature revealed that COF occurs in the fourth to fifth decade, exhibits no sex difference, and has a good prognosis after surgery. Radiographic images of COF occasionally mimic dentigerous cysts, but there are no particular radiographic features distinguishing COF. Diagnosis is usually based on histological findings. Immunohistological studies may also be useful in the diagnosis of COF.

Central odontogenic fibroma: a case report

Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Here, a case of central odontogenic fibroma in a 17-year-old male is reported. Since the present case showed a multilocular radiolucency with partially ill-defined border between the right mandibular condyle and the distal root of the right mandibular third molar, differential diagnosis involved a wide range of pathosis from benign lesions like ameoloblastic fibroma and odontogenic myxoma to more aggressive lesions such as desmoplastic fibroma, juvenile aggressive fibromatosis, or fibrosarcoma.

Central odontogenic fibroma of the maxilla: a case report with immunohistochemical study

A rare case of central odontogenic fibroma of the maxilla is presented. A 29-yearold man was admitted because of movable right lateral incisor and dull pain. Panoramic radiograph showed a well-demarcated unilocular radiolucent lesion in the right anterior region of the maxilla. The enucleated tumor was a well-defined firm mass with a solid yellowish-white appearance. Histologically, the tumor was composed of minimally cellular collagenous connective tissue with myxoid matrix. Small epithelial islands were scanty, scattered and inactive appearing in the connective tissue. Immunohistochemically, the fibroblastic cells were positive for vimentin, and the epithelial islands were positive for cytokeratin 14 (CK14) and CK19, which are markers of odontogenic epithelium. From these findings, the tumor was diagnosed as an epithelium-poor type of central odontogenic fibroma. No recurrence has been noted 14 months after surgery.

Central odontogenic fibroma of the mandible: a case report

Central odontogenic fibroma (COF) is a rare tumor that accounts for 0.1% of all odontogenic tumors. It has been defined as a benign neoplasm, which appears in the jaw. Clinically, the lesion grows slowly and leads to cortical expansion. Radiologically, the most common finding is multilocular radiolucency. In some cases, it may be associated with root resorption or displacement. Histologically, the lesion is characterized by mature collagen fibers and numerous fibroblasts. COF responds well to surgical enucleation with no tendency for malignancy or recurrence. Here, a case of central odontogenic fibroma of the mandible in a 71-year-old man is described. The lesion was an asymptomatic mass with well-defined borders covered by normal mucosa. The lesion presented as a multilocular radiolucency in relation to the root of the canine. The lesion was surgically removed and analyzed histopathologically. There were no postoperative complications.

Rare odontogenic tumor of the mandible

Central odontogenic fibroma is an extremely rare benign tumor accounting for less than 0.1% of all odontogenic tumors. This case report describes a case of central odontogenic fibroma arising in relation to the left lower second premolar and first molar in a 21 year old male. The tumor was a well-circumscribed intraosseous lesion occurring inter-radicularly, which gave a radiographic picture of the lateral periodontal cyst. Histopathologically, the lesion was reported to have characteristic features of central odontogenic fibroma.

Central odontogenic fibroma, granular cell variant

A case of central odontogenic fibroma (COF) of the epithelium-rich type (granular cell variant) is reported. A 46-year-old female, demonstrated a multilocular, septated radiolucency below and between the roots of the teeth in 44–47 region. On microscopy the lesion revealed an odontogenic fibroma of the epithelium-rich type with areas characterized by lobules of spherical cells of varying size containing fine S-100 negative granules. In addition, scattered foci of cementoid/osteoid calcified material occurred. Based on several studies, the present authors entertain the hypothesis that supports a histiocystic origin the granular cells. Therapy consisted of curettage of the lesion. The defect was filled with spongeous bone. No recurrence occurred after follow-up of two years.

Central odontogenic fibroma of mandible: A case report and review of the literature

Central odontogenic fibroma is an extremely rare benign tumor, accounting for less than 0.1% of all odontogenic tumors. The most recent literature review revealed that only 69 cases have so far been reported in the English literature, and only 1 of these cases showed radiologic appearance of a dentigerous cyst and this involved impacted maxillary incisors. A case of central odontogenic fibroma occurring in the mandible of a 30-year old female with radiological appearance of a dentigerous cyst involving an impacted lower first molar, presented here, appears to be the first reported case of central odontogenic fibroma of mandible with radiological appearance of dentigerous cyst in the English-language literature.

The simple central odontogenic fibroma: A case report

A rare case of central odontogenic fibroma - a simple type according to Gardner's classification - is presented. Clinical manifestations and treatment are described. The aetiology and histopathological differential diagnosis are discussed.

Central odontogenic fibroma

The article presents a case of central odontogenic fibroma occurring in the maxilla. The literature is reviewed, in the belief that a discussion of the controversial issues surrounding this neoplasm, its treatment and follow-up information, is warranted, due to the small number of cases (13) of this tumor that have been recognised and reported up to the present.

Central odontogenicfibroma a case report

A case of central odontogenic fibroma is reported. The clinical, radiological and pathological features are discussed. It is of particular interest because of its maxillary location and the severe external root resorption associated with the tumour.