Case Of Acute Type Research Articles

A Case of Acute Type A Aortic Dissection with Liver Injury of Unknown Cause

A Case of Acute Type A Aortic Dissection with Liver Injury of Unknown Cause

A Case of Acute Type A Aortic Dissection with Malperfusion of the LMT with a History of Open-Heart Surgery

A Case of Acute Type A Aortic Dissection with Malperfusion of the LMT with a History of Open-Heart Surgery

A Case of Acute Type A Aortic Dissection Complicated with High-Altitude Pulmonary Edema

A Case of Acute Type A Aortic Dissection Complicated with High-Altitude Pulmonary Edema

Clinical characteristics of immune checkpoint inhibitor-related type 1 diabetes mellitus

The clinical data of ten patients with immune checkpoint inhibitor-related type 1 diabetes mellitus were enrolled in the Second Xiangya Hospital of Central South University from January 2020 to October 2022 including 9 males and 1 female, with an average age of (57±8) years. There were 7 cases of fulminant type 1 diabetes and 3 cases of acute type 1 diabetes. Among the 10 patients, there were 5 cases of lung cancer, 2 cases of esophageal cancer, 1 case of gastric carcinom, 1 case of renal cell carcinoma, and 1 case of nasopharyngeal cancer. The drugs used in 10 patients were all programmed cell death receptor 1 (PD-1) inhibitors, including 5 cases of pembrolizumab, 3 cases of sintilimab, 1 case of tanezumab, and 1 case of toripalimab. Among them, 8 patients had diabetic ketoacidosis (DKA), 1 patient had ketosis, and 1 case had no ketosis at onset; 9 patients were negative for diabetes-related antibodies, and 1 patient was positive. All the 10 patients were successfully treated and depended on insulin therapy. Immune checkpoint inhibitors can cause type 1 diabetes, including fulminant type 1 diabetes, which mostly begins with DKA, requiring early identification and aggressive insulin therapy.

Frozen Elephant Trunk: Technical Overview and Our Experience with a Patient-Tailored Approach.

Ever since the first hybrid prosthesis was used for a total aortic arch replacement, many other techniques have been developed to comply with the need for the treatment of a wide spectrum of patients and their clinical pictures. We hereby provide an overview of the most popular surgical techniques to perform a frozen elephant trunk, including our tailored approach revolving around the antegrade deployment of a Gore C-TAG endovascular stent graft sutured to a four-branched vascular prosthesis. This technique was applied to three cases of acute type A aortic dissection. Although our small series of patients consists of acute aortic dissections only, this technique could be applied to any other aortic arch pathology, such as chronic dissections or aneurysms. Moreover, we believe that, because of the individually tailored approach and widespread availability of the necessary materials, this technique can reveal itself useful in many different operative scenarios.

A Case of Acute Type B Aortic Dissection with Visceral Malperfusion and Impending Rupture of Abdominal Aortic Aneurysm

A Case of Acute Type B Aortic Dissection with Visceral Malperfusion and Impending Rupture of Abdominal Aortic Aneurysm

Single-Center Vascular Hub Experience after 7 weeks of COVID-19 Pandemic in Lombardy (Italy)

BackgroundThe aim of this study was to report the experience of one of the major “hubs” for vascular surgery in Lombardy, Italy, during the first 7 weeks after total lockdown due to COVID-19 pandemic.MethodsData from all patients treated at our Department since the decision of the regional healthcare authorities of Lombardy to centralize surgical specialties creating a hub/spoke system (March 9, 2020) were prospectively collected and compared with a retrospectively collected cohort from the same period of year 2019. Primary study end point was defined as primary clinical success. Secondary end points were defined as in-hospital mortality and/or any in hospital major adverse event or lower limb amputation.ResultsOne hundred sixteen patients were treated (81 men, 70%; median age: 71 years, IQR 65–81). Thirty-two patients (28%) were addressed from spoke hospitals directly referring to our hub, 19 (16%) from hospitals belonging to other hub/spoke nets, 48 (41%) came directly from our emergency department, and 17 (15%) were already hospitalized for COVID-19 pneumonia. Acute limb ischemia was the most observed disease, occurring in 31 (26.7%), 12 (38.7%) of whom were found positive for COVID-19 pneumonia on admission, whereas 3 (9.7%) became positive during hospitalization. Chronic limb ischemia was the indication to treatment in 24 (20.7%) patients. Six (5.2%) patients underwent primary amputation for irreversible ischemia. Aortic emergencies included 21 cases (18.1%), including 13 (61.9%) symptomatic abdominal aortic or iliac aneurysms, 4 (19.0%) thoracoabdominal aortic aneurysms, 2 (9.5%) cases of acute type B aortic dissection (one post-traumatic). Seventeen (14.7%) patients were admitted for symptomatic carotid stenosis (no COVID-19 patients); all of them underwent carotid endarterectomy. Seventeen (14.7%) cases were treated for other vascular emergencies. Overall, at a median follow-up of 23 ± 13 days, primary clinical success was 87.1% and secondary clinical success was 95.9%. We recorded 3 in-hospital deaths for an overall mortality rate of 2.6%. Compared with the 2019 cohort, “COVID era” patients were older (72 vs. 63 years, P = 0.002), more frequently transferred from other hospitals (44% vs. 21%, P = 0.014) and more frequently with decompensated chronic limb threatening ischemia (21% vs. 3%, P = 0.015); surgical outcomes were similar between the 2 cohorts.ConclusionsSince its appearance, SARS-CoV-2 has been testing all national healthcare systems which founds themselves facing an unprecedented emergency. Late referral in the pandemic period could seriously worsen limb prognosis; this aspect should be known and addressed by health care providers. Vascular surgical outcomes in pre-COVID and COVID era were comparable in our experience.

A Case of Acute Type B Aortic Dissection Subsequent to Asymptomatic Chronic Type A Aortic Dissection Which Was Difficult to Distinguish from Acute Type A Aortic Dissection

A Case of Acute Type B Aortic Dissection Subsequent to Asymptomatic Chronic Type A Aortic Dissection Which Was Difficult to Distinguish from Acute Type A Aortic Dissection

A Case of Acute Type A Aortic Dissection with Double Aortic Arch.

Double aortic arch (DAA) is extremely rare in adults. A 71-year-old woman suffered from syncope, and an acute-type aortic dissection with a DAA accompanied by a massive pericardial effusion was shown in a non-enhanced computed tomography (CT). Enhanced CT was not performed because of her hemodynamic instability. She was rushed to the operating theater after immediate pericardiocentesis without more precise morphological evaluation. Ascending aortic replacement was performed by clamping both aortic arches without systemic circulatory arrest. She survived the operation, but her respiratory function was affected by tracheomalacia and remaining DAA with residual dissection.

Acute type A aortic dissection repair in an octogenarian with achondroplasia: a case report

BackgroundAchondroplasia is an inherited disorder and the most common type of short-limbed dwarfism in human beings, affecting more than 250,000 individuals worldwide. To the best of our knowledge, no study has reported a correlation between achondroplasia and aortic dissection. Here, we report a rare case of acute type A aortic dissection repair in a patient with achondroplasia.Case presentationAn 82-year-old Japanese female with achondroplasia was admitted to our hospital because of acute-onset severe chest pain migration to her back accompanied by numbness and pain in the right lower limb. A computed tomography scan revealed acute type A aortic dissection with right leg ischemia because of an occlusion of the right common iliac artery. We successfully performed hemiarch repair.ConclusionsThis report presents the first case of a patient at such an advanced age with dwarfism and cardiac surgery and the second case to illustrate successful acute aortic dissection repair in achondroplasia. Of note, all procedures were performed without specialized equipment. Overall, this report adds to the experience of successful cardiac surgery in this unique patient population.

Right Axillary Artery Cannulation for Endovascular Repair of an Acute type a Aortic Dissection

We present the case of a 48-year-old woman with an acute type A aortic dissection that was treated with thoracic endovascular aortic repair at our institution. The patient was found to have a focal type A dissection with pericardial effusion but no tamponade physiology and no involvement of the aortic valve or root. We elected to treat the patient's type A aortic dissection with an endovascular stent because of the patient's favorable anatomy and no evidence of neurologic deficits or signs of distal malperfusion. The patient was successfully treated with an abdominal aortic cuff deployed through the axillary artery. An axillary approach was necessary because of the short length of the delivery sheath preventing a transfemoral delivery. At 2-year follow-up, the patient remains free of complications with computed tomography scan revealing complete false lumen thrombosis and a stable endovascular repair. This report demonstrates a case of acute type A aortic dissection successfully treated using thoracic endovascular aortic repair and illustrates the utility of axillary cannulation for precise deployment of stent grafts in the ascending aorta.

Acute Type B Dissection Complicated by Aortic Coarctation

We report a case of acute type B aortic dissection complicated by coarctation of aorta in 35-year-old women. Computed tomography angiography (CTA) showed a short segment aortic narrowing with diameter of 9.2 mm a small intimal tear, a true lumen, a false lumen, a markedly thick mural thrombus and pleural effusion. Open surgical procedure was performed and the aortic coarctation (CoA) and aortic dissection were resected and a 24-mm prosthetic graft was anastomosed. No pseudo aneurysms were present at the anastomosis sites on the follow up CTA.

両側冠動脈解離を伴う Stanford A 型急性大動脈解離に対し LMT ステント留置後に上行大動脈置換術および冠動脈バイパス術を施行した1例

45歳男性．突発する胸痛で救急搬送された．来院時ショックバイタルであり，心電図所見から急性冠症候群と診断され，大動脈内バルーンパンピングを挿入後に緊急冠動脈造影（CAG）を施行された．CAGの結果，急性A型大動脈解離であり，左右冠動脈に解離が及んでいた．緊急手術の準備中に再度循環動態の維持が困難となり，左冠動脈主幹部（LMT）にベアメタルステントを用いた経皮的冠動脈形成術（PCI）を施行し，循環動態を安定させた後に上行大動脈置換術および冠動脈バイパス術を行い救命し得た．冠動脈解離を合併し，手術までの間に血行動態が維持できない急性A型大動脈解離に対し，PCIを先行させ血行動態を安定させたうえでの手術は治療戦略の1つとして考慮されよう．

A case of acute Type A Stanford aortic dissection where pulmonary artery dissection was suspected from preoperative CT findings

A case of acute Type A Stanford aortic dissection where pulmonary artery dissection was suspected from preoperative CT findings

Aortic Dissection Presented as Paraparesis: A Case Report with Literature Review

One case of acute type B aortic dissection presented with paraparesis and retrosternal chest pain was treated conservatively with warfarin and blood pressure control with good recovery of symptoms. A literature review including 25 cases of aortic dissection presented with paraparesis/paraplegia from year 1980 to 2010 is also presented.

右共同偏視，左片麻痺で発症した Stanford A 型急性大動脈解離の1例

右共同偏視，左片麻痺で発症した Stanford A 型急性大動脈解離の1例

脊髄保護における選択的脳灌流の役割

脊髄保護における選択的脳灌流の役割

Acute type B aortic dissection and coarctation: open stent-graft elephant trunk

We describe a case of acute type B dissection associated with coarctation of the aorta. An intimal tear was located just distal to the coarctation. Aortic dilatation started below the coarctation and extended to the level of the diaphragm. We performed descending aorta replacement from the distal aortic arch to the level of the 9(th) intercostal arteries, and implanted a stent-graft elephant trunk through a left posterior lateral thoracotomy in the 5(th) intercostal space off-pump.

Thromboelastometry Based Early Goal-Directed Coagulation Management Reduces Blood Transfusion Requirements, Adverse Events, and Costs in Acute Type A Aortic Dissection: A Pilot Study

Background: In aortic surgery bleeding complications can be fatal. Therefore, rotational thromboelastometry(ROTEM^TM)based coagulation management was introduced. Methods: After 5 cases of acute type A aortic dissection and aortic arch replacement had been treated based on ROTEM findings (ROTEM group; RG), 5 cases without ROTEM were matched as control group (CG). CG treatment was based on conventional tests and clinical findings. Blood component and coagulation factor requirements, ventilation time, duration of stay at intensive care unit (ICU), hospitalization, and thrombotic or bleeding incidents as well as transfusion-associated costs were compared. Results: Administration of blood products and coagulation factor concentrates, ventilation time, ICU length of stay, and hospitalization tended to be lower in RG. Postoperative plasma transfusion (p = 0.038), recognized incidents (p = 0.048), and resulting costs on coagulation treatment (p = 0.049) were significantly reduced. Conclusion: Our data suggest that ROTEM-based coagulation management can reduce transfusion requirements and corresponding costs in patients with aortic arch replacement. These data has to be confirmed by prospective randomized trials.

Direct Admission to the Operating Room: An Efficient Strategy for Patients With Diagnosed or Highly Suspected Acute Type A Aortic Dissection

Background Acute type A aortic dissection (ATAAD) is a life-threatening condition with a poor acute prognosis, which requires rapid and effective surgical management. The aim of this study is to assess our strategy with regard to this condition. Methods According to a regional emergency protocol, patients with diagnosed or highly suspected ATAAD are directly transferred to the cardiac operating room. Transesophageal echocardiography is performed under anaesthesia, and the patient then undergoes surgery if the diagnosis is confirmed. The present retrospective study examines the implementation of this management strategy between January 1, 1990 and December 31, 2009. Results Out of 380 patients, 245 were directly admitted to the operating room. Three hundred twelve cases of ATAAD, 15 cases of aneurysm of the ascending aorta, 9 cases of acute type B dissection, 4 cases of chronic dissection, 4 cases of hemopericardium, and 7 other diagnoses were observed. In 10 cases, no etiology was found. Nineteen patients died before surgery could be performed. Out of the 307 cases of ATAAD undergoing surgery, 15 patients were operated with cardiac massage (14 cases of aortic rupture). This management strategy was justified in 93.1% of patients (228/245) directly admitted to the operating room, because of the need for surgery or aortic rupture. Conclusions Our management strategy enabled patients with ATAAD to receive effective and unselective treatment. Despite appropriate management, the large number of patients still dying before surgery, or undergoing surgery with cardiac massage, justifies and consolidates the need for immediate treatment of this condition.