OPEN ACCESSNovember 18, 2013Eric Smith - A Renal Physiology Case-based Learning Exercise Ansley Splinter, MD, MACM, Daniel Castellanos, Carla Lupi, MD Ansley Splinter, MD, MACM Florida International University Herbert Wertheim College of Medicine Google Scholar More articles by this author , Daniel Castellanos Children's Hospital Los Angeles Google Scholar More articles by this author , Carla Lupi, MD Florida International University Google Scholar More articles by this author https://doi.org/10.15766/mep_2374-8265.9609 SectionsAbout ToolsDownload Citations ShareFacebookTwitterEmail AbstractAbstract Introduction: This progressively disclosed case of a boy presenting with generalized edema was created as part of a case-based learning course for second- and third-year medical students and was designed to integrate with basic science and clinical learning. The case provides a strong opportunity for initial learning and/or targeted review of important pathophysiologic concepts. Methods: This case is designed for the small-group format; we have used it with groups ranging from four to eight students. When possible, groups have been facilitated by one basic science and one clinical faculty member. Nonetheless, a clinician well versed in the case and familiar with basic renal physiology can run the session alone. Results: We have used this case during our second-year organ system courses. Student ratings of this case have been uniformly high, with the common reaction that the case is critical in helping them integrate lecture and laboratory-based learning. They prefer to participate in these exercises toward the end of the organ system module, citing greater integrative value at this point. Discussion: We have found that initial participation in this case is preparing students well for robust involvement in the more open-ended and complex problem-based learning cases of our third year. We have yet to conduct any systematic assessment of learning from participation in these cases. Educational Objectives By the end of this case, learners will be able to: Explain the mechanism by which pathophysiologic changes in different organ systems can cause generalized edema.Identify laboratory tests necessary to diagnose a patient with generalized edema.Interpret laboratory test results to narrow a differential diagnosis.List the diagnostic criteria for nephrotic syndrome in a pediatric patient.Propose a treatment plan for a patient with nephrotic syndrome, edema, and respiratory distress.Describe the complications of nephrotic syndrome including the pathophysiology underlying those complications.Describe Starling forces and how they contribute to edema formation.Describe the normal barriers to protein filtration in the kidney.List the layers of the glomerular filtration barrier.Explain the pathophysiologic mechanisms of proteinuria.Explain the relationship between total calcium levels and albumin levels.Explain the renal primary defect that results in nephrotic syndrome.Explain the mechanism of action and common side effects of loop and thiazide diuretics. Sign up for the latest publications from MedEdPORTAL Add your email below FILES INCLUDEDReferencesRelatedDetails FILES INCLUDED Included in this publication: Eric Smith Instructor's Guide.docx Eric Smith Facilitator Version.docx Eric Smith Student Version.docx Student Participation Rubric.docx To view all publication components, extract (i.e., unzip) them from the downloaded .zip file. Download editor’s noteThis publication may contain technology or a display format that is no longer in use. Copyright & Permissions© 2013 Splinter et al. This is an open-access publication distributed under the terms of the Creative Commons Attribution-NonCommercial-Share Alike license.KeywordsCase-Based LearningUndergraduateRenal PhysiologyUndergraduate Medical EducationEducationSecond-Year Medical StudentsNephrotic SyndromeThird-Year Medical StudentsMedical Disclosures None to report. Funding/Support None to report. Loading ...
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