Development Of Carious Lesions Research Articles

The Assessment of Resin-Based Composite Sealants' Effectiveness in Arresting Non-Cavitated Dentin Carious Lesions (ICDAS 3)-A 12 Month Follow-Up Preliminary Study.

Background and Objectives: The therapeutic management of carious lesions remains a significant focus for researchers, given their persistently high prevalence despite being largely preventable. This study aimed to compare the effectiveness of a composite resin-based sealant material in halting extended non-cavitated dentin carious lesions when used therapeutically versus preventively on caries-free teeth over a period of twelve months. Materials and Methods: out of the 236 children examined, 45 were excluded from the study due to non-compliance with the inclusion criteria. Thus, the study included 191 children aged 10-12 years, and 764 molars in total. Results: among these molars, 171 were caries-free (ICDAS II code 0), forming the Control group, while 180 molars were classified with an ICDAS II score of 3, forming the Study group. All molars were sealed and evaluated at 6- and 12-month follow-up intervals. Both intervals revealed statistically significant differences (p < 0.05) in sealant retention and carious lesion development between sound (ICDAS code 0) and decayed (ICDAS code 3) teeth. Conclusions: the findings did not support the effectiveness of sealants in halting non-cavitated dentin carious lesions classified as ICDAS II with code 3 compared to their preventive application in sound teeth classified as ICDAS II with code 0.

Silver Diamine Fluoride in Pediatric Dentistry: Effectiveness in Preventing and Arresting Dental Caries-A Systematic Review.

Tooth decay is considered a global scourge by the World Health Organization (WHO) starting at an early age. In recent years, silver diamine fluoride (SDF) has regained interest, particularly in pediatric dentistry, used to prevent the development of carious lesions or arrest their progression. The aim of this study was to assess, through a systematic review of the literature, the effectiveness of SDF, used in pedodontics, in temporary teeth, in preventing or arresting dental caries. An electronic search was conducted on PubMed, Web of Science and Scopus. The effect of SDF on both temporary and permanent teeth has been considered. The inclusion criteria identified 16 randomized controlled trials involving patients aged 18 months to 13 years and followed over a period of 12-30 months. SDF is a practical, accessible and effective non-invasive way to prevent and arrest caries in temporary and permanent teeth. Its application requires regular monitoring. The resulting black spot is diminished by immediate application of potassium iodide but this may affect its effectiveness.

The Efficacy of Silver Diamine Fluoride as a Caries Preventive Agent on Permanent Teeth: A Scoping Review

AbstractDental caries is a chronic condition that affects people of all ages and has a high prevalence in Indonesia. Applying silver diamine fluoride (SDF) as a topical fluoridation agent is one of the approaches to prevent bacterial interactions that lead to the development of carious lesions. This study aims to determine the efficacy of SDF as a caries preventive agent on permanent teeth. Article searches were conducted using the keywords “silver diamine fluoride” AND “permanent tooth OR permanent teeth” AND “caries OR dental caries” AND “remineralize” through digital databases including PubMed, Cochrane Library, Science Direct, and Google Scholar. Articles with randomized controlled trial or nonrandomized controlled trial designs, articles written in Indonesian or English, publications published within the last 5 years (2016–2021), and aligned with the PCC (population, concept, and context) framework were included. Articles that were not accessible in full text or in a paid format, those that were of the meta-analysis or systematic review study type, and those that did not evaluate the use of SDF as a caries preventive agent were excluded from consideration. This scoping review refers to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extensions for Scoping Reviews (PRISMA-ScR) guidelines. A total of 8 articles were reviewed, encompassing various locations, designs, and samples, which demonstrated the use of SDF resulted in a high percentage of fluoride release with a high degree of remineralization efficacy. The deposition of crystals or minerals into fissures and crevices caused by demineralization indicated a reduction in lesion depth and influenced the microhardness of enamel. SDF can stimulate the rehardening of tooth structures rich in calcium and phosphate. The solution of SDF has the potential to serve as an alternative substance for preventing caries in permanent teeth because it enhances mineral precipitation and mineral density, promotes the remineralization of hydroxyapatite in enamel by increasing fluoride, and increases tooth structure resistance to acid attack.

The Impact of Molar Incisor Hypomineralisation on Children and Adolescents: A Narrative Review

Molar incisor hypomineralisation (MIH) is a qualitative developmental enamel defect with a prevalence of 13% worldwide. This review aims to outline the current evidence regarding the impact of MIH on children’s oral health and, more broadly, their day-to-day activities. MIH is associated with negative sequelae, including hypersensitivity, post-eruptive breakdown, the rapid development of carious lesions and poor aesthetics. Other concerns pertain to the clinical management of MIH and include difficulty in achieving local anaesthesia, increased dental fear and anxiety (DFA) and increased behaviour management problems. Oral health-related quality of life (OHRQoL) is the most standardised measure of patient impact; however, no instruments have been validated for use in MIH populations. The few existing observational studies investigating the impact of MIH on OHRQoL in children have produced conflicting results. Interventions to alleviate hypersensitivity and improve aesthetics had a positive impact on the OHRQoL of MIH-affected children. Multiple methodological issues make it difficult to measure the impact of MIH, including heterogeneity in the MIH severity classification, an overlap in the indices used to diagnose dental caries and MIH as well as the subjectivity of outcome measures for hypersensitivity and DFA.

ON THE POSSIBILITIES AND STRATEGIES FOR INCORPORATION ANTIMICROBIAL AGENTS INTO RESIN COMPOSITE DENTAL MATERIALS – A NARRATIVE REVIEW

Because of the high frequency of recurrent caries following composite resin restorative treatment, as well as the large number of cariogenic microorganisms present in the oral cavity, which represent a potential risk factor for the development of new carious lesions, the antimicrobial effects of composite resins are receiving increasing attention. Recently, attempts have been made to include specific antimicrobial compounds in restorative materials, mainly GJCs and composites, in addition to fluorides. Conventional composites’ lack of antibacterial qualities implies a lack of an inhibitory impact against plaque accumulation on their surface, allowing bacteria such as mutans streptococci to grow freely. As a result, the antibacterial properties of dental resin composites are crucial to their therapeutic applications. The present study demonstrates the methods and possibilities for incorporating antimicrobial chemicals, both leachable and non-leachable, into the resin matrix or filler of composite resins.

Photobiomodulation efficacy of major salivary glands in children with caries activity: study protocol for randomized, double-blind, placebo-controlled, parallel-group clinical trial

Background: Dental caries is one of the most prevalent diseases among children worldwide. Saliva plays a significant role in the demineralization/remineralization of the dental surface. Several salivary characteristics, such as flow rate, pH, and buffering capacity, provide relevant information regarding the development of carious lesions. Photobiomodulation has shown promising results in improving salivary flow rate and buffer capacity in the adult population. Purpose: of this trial was to evaluate the efficacy of photobiomodulation of the major salivary glands on salivary parameters in children with caries. Methods: This protocol details a randomized, double-blind, parallel-group, controlled trial that evaluated salivary parameters through photobiomodulation in children. Fifty 6- to 12-year-old participants will be randomly divided into two groups:1) photobiomodulation experimental group (G1) (n=25) and 2) photobiomodulation placebo group (G2) (n=25). Infrared light will be applied at 16 intra-and extraoral points and placebo, respectively. Unstimulated salivary samples will be collected before and immediately after application once a week for three consecutive weeks. Salivary samples will be analyzed for their flow rate, pH, and buffering capacity. The primary outcomes are the differences in salivary flow rates between G1 and G2. The secondary outcomes are differences in salivary pH and buffering capacity between G1 and G2.Discussion: The results of this clinical trial will offer evidence for the efficacy of photobiomodulation in salivary parameters and to support decision-making regarding non-invasive treatments to control dental caries.

Determinants of Microscale pH in In Situ-Grown Dental Biofilms.

Dental biofilm pH is the most important determinant of virulence for the development of caries lesions. Confocal microscopy-based pH ratiometry allows monitoring biofilm pH with high spatial resolution. Experiments performed on simplified biofilm models under static conditions identified steep pH gradients as well as localized acidogenic foci that promote enamel demineralization. The present work used pH ratiometry to perform a comprehensive analysis of the effect of whole saliva flow on the microscale pH in complex, in situ-grown 48-h and 96-h biofilms (n = 54) from 9 healthy participants. pH was monitored in 12 areas at the biofilm bottom and top, and saliva flow with film thicknesses corresponding to those in the oral cavity was provided by an additively manufactured microfluidic flow cell. Biofilm pH was correlated to the bacterial composition, as determined by 16S rRNA gene sequencing. Biofilm acidogenicity varied considerably between participants and individual biofilms but also between different areas inside one biofilm, with pH gradients of up to 2 units. pH drops were more pronounced in 96-h than in 48-h biofilms (P = 0.0121) and virtually unaffected by unstimulated saliva flow (0.8 mm/min). Stimulated flow (8 mm/min) raised average biofilm pH to near-neutral values but it did not equilibrate vertical and horizontal pH gradients in the biofilms. pH was significantly lower at the biofilm base than at the top (P < 0.0001) and lower downstream than upstream (P = 0.0046), due to an accumulation of acids along the flow path. pH drops were positively correlated with biofilm thickness and negatively with the thickness of the saliva film covering the biofilm. Bacterial community composition was significantly different between biofilms with strong and weak pH responses but not their species richness. The present experimental study demonstrates that stimulated saliva flow, saliva film thickness, biofilm age, biofilm thickness, and bacterial composition are important modulators of microscale pH in dental biofilms.

Is Mutans Streptococci count a risk predictor of Early Childhood Caries? A systematic review and meta-analysis

BackgroundThe review aims to determine the risk predictability of mutans streptococci in the development of carious lesions in children with primary dentition.MethodsLongitudinal observational studies with at least 6 months follow-up and evaluating mutans streptococci presence in caries-free children under 6 years of age for the development of any cavitated or non-cavitated carious lesion. Six databases and grey literature were searched without any restrictions. Risk of bias was evaluated using the New Castle Ottawa scale for longitudinal studies, and the certainty of the evidence was evaluated by Grading of Recommendations Assessment, Development and Evaluation using GRADEpro software. Meta-analysis was performed using a random effect (DerSimonian and Laird, DL) model, and heterogeneity was evaluated using tau-squared, I2 statistics and prediction interval. Sensitivity analysis was performed to assess the relationship between the mutans streptococci presence at baseline and the caries development, according to the sample and methods used for the microbiological assessment and the length of follow-up of the studies. Publication bias was checked by funnel plot using a random effect (DerSimonian and Laird, DL) model.ResultsTwelve studies met the inclusion criteria and were included in the review. Four studies received a maximum of 9 stars, and among the remaining eight studies, six received 8 stars and the rest two studies were assigned 7 stars in the risk of bias scale. After pooling the results quantitatively, odds ratio (OR) was found to be 4.13 (95% CI: 3.33, 5.12), suggesting that children with mutans streptococci had 4 times higher odds of developing caries later (p < 0.001). Four studies were pooled to compare future caries experience among children with and without mutans streptococci at baseline, obtaining standardized mean difference (SMD) of 0.85 (95% CI: 0.33, 1.37), indicating a large effect (p < 0.001). Certainty of evidence was found to be moderate, and no publication bias was reported by the funnel plot criteria of symmetry.ConclusionsPresence of mutans streptococci in a preschool child is a risk predictor for future caries experience. Early identification of children with increased caries-risk may facilitate in implementation of appropriate preventive strategies.

Anti-caries Streptococcus spp.: A potential preventive tool for special needs patients.

Probiotics are living microorganisms that act on the host-microbiome interface to restore the microbiota's physiological homeostasis. Numerous probiotics have been marketed with inhibitory activity against Streptococcus mutans and consequently with a potential anti-caries effect, mainly of the genera Lactobacillus and Bifidobacterium, whose main disadvantage is their limited ability to settle in the oral cavity. This narrative review describes the main Streptococcus spp. with probiotic anti-Streptococcus mutans activity, whose substantivity is greater than that of Lactobacillus spp. and consequently with anti-caries potentiality. We performed a literature review in the PubMed, Science Direct and Google Scholar databases of articles published in English (without time restriction) related to caries and probiotics. The potential identified anti-caries probiotics included Streptococcus spp. A12, Streptococcus oralis (AJ3), Streptococcus oligofermentans, Streptococcus salivarius (K12, M18, JH, LAB813, 24SMB), Streptococcus spp. with arginolytic activity (S. sanguinis, S. gordonii, S. ratti, S. parasanguinis, S. intermedius, S. australis, and S. cristatus), Streptococcus rattus (JH145), Streptococcus dentisani and Streptococcus downii. The possibility of using these Streptococcus spp. as probiotics that inhibit the growth of dental plaque and the development of carious lesions represents a potential tool of particular interest for individuals with physical or intellectual disabilities that impede the routine and effective application of mechanical dental plaque removal techniques.

Dens Invaginatus: Literature Review and Case Report

Dens invaginatus (DI) represents a structural defect in the tooth, resulting from invagination of enamel organ into the dental papilla. This rare anomaly, which often goes unnoticed during a clinical examination, is a risk factor for the development of carious lesions and consequently pulpopathies. The knowledge of this type of lesions allows to ensure early diagnosis and thus avoid any complications. This article represents a case report of dens invaginatus along with a literature review regarding etiology, classification, clinical appearance, and diagnosis. It provides also guidelines for decision-making and treatment of invaginated teeth

Efficacy of bioactive materials in preventing Streptococcus mutans-induced caries on enamel and dentine.

The study investigated the ability of bioactive materials used to restore enamel and dentine specimens to prevent caries. Enamel (n=50) and dentine (n=50) specimens were obtained from bovine incisors, prepared, and randomly allocated to one of five groups according to the restorative treatment: alkasite without adhesive system; alkasite with adhesive system; high viscosity glass ionomer cement; resin composite; no restoration; negative control group. Specimens were restored, exposed to a thermal cycling aging protocol, sterilized, and exposed to a cariogenic challenge induced by Streptococcus mutans and then submitted to surface and subsurface microhardness tests and polarized light microscopy to verify the caries lesion development in enamel or dentine surrounding the restorative materials. Data were analyzed using one-way ANOVA. In enamel and dentine, glass ionomer cement, alkasite without and with adhesive system presented a lower percentage surface microhardness loss than resin composite and negative control. Enamel subsurface microhardness presented no statistically significant differences between glass ionomer cement, alkasite without and with adhesive system. Glass ionomer cement also did not present statistically significant differences from resin composite and the negative control. In dentine, glass ionomer cement showed the highest subsurface microhardness values. In conclusion, bioactive restorative materials provide greater protection to enamel and dentine against surface caries development than resin composite.

Clinical Features of the Development and Treatment of Carious and Non-carious Lesions in the Cervical Area of Human Teeth

Clinical Features of the Development and Treatment of Carious and Non-carious Lesions in the Cervical Area of Human Teeth

Matrix Metalloproteinases in Oral Health—Special Attention on MMP-8

Matrix metalloproteinases (MMPs) are a large family of Ca2+ and Zn2+ dependent proteolytic enzymes, able to cleave the various components of the extracellular matrix (ECM), as well as a range of other regulatory molecules. Several reports have proven the important role of both MMPs and their endogenous inhibitors, TIPMs, in oral health, the initial development of the tooth, and during enamel maturation. In this mini-review, we aim to summarize the literature information about the functions of MMPs, paying more attention to MMP-8 (collagenase-2 or neutrophil collagenase) in the development and progression of periodontitis, peri-implantitis, and carious lesions. We also emphasize the role of particular gene variants in MMP8 as predisposing factors for some oral diseases.

One-year follow-up of microscopical and clinical behavior of bioactive self-etching resin sealant.

The development of early carious lesions can be prevented with the use of sealants. This study aimed to evaluate the retention and sealant quality of conventional and bioactive self-etching sealants by direct (clinical) and indirect (microscopical) assessment. Sixty newly erupted mandibular second molars (International Caries Detection and Assessment System ≤2) from adolescents were selected for the split-mouth trial study. The tooth was randomized and treated with conventional Fluoroshield (FS) and BeautiSealant (BS) bioactive self-etching sealants. Molds were taken and cast with epoxy resin after treatment. Indirect and direct assessments of retention degree and sealant remnant quality were performed after baseline, 1 month, and 1 year. The Chi-square test, ordinal regression, reasons of chance, and Fleiss' kappa statistical test were employed. After 1 month, greater total retention was observed for FS, but 1-year follow-up demonstrated no retention difference for FS and BS. The odds ratios showed an 86% greater chance of FS showing better marginal adaptation, after 1 month. At 1 year, the clinical assessment showed better anatomical shape and marginal adaptation scores for FS, but no microscopical difference was observed. A pour agreement between clinical and microscopical data was observed. The 1-year follow-up showed no significant difference in the degree of retention, and in the microscopic evaluation of the conventional sealant (FS) and the bioactive self-etching sealant (BS), but in the clinical evaluation, better marginal and anatomical adaptation scores for FS were observed.

DIAGNOdent versus International Caries Detection and Assessment System in detection of incipient carious lesions: A diagnostic accuracy study.

The present investigation aimed at assessing the diagnostic accuracy of DIAGNOdent compared to the International Caries Detection and Assessment System-II (ICDAS-II) in the detection of facial, smooth surface noncavitated carious lesions. Sixty patients were enrolled in the current study according to the eligibility criteria. There were 161 teeth with noncavitated, white spot carious lesions and 32 sound teeth. Before examination, teeth were cleaned and polished and all patients were assessed under standardized operating conditions: preset dental unit position, operating light, and prolonged air drying (approximately 5 s). All teeth were assessed by two calibrated examiners individually without any contact using ICDAS-II and DIAGNOdent. The diagnostic accuracy of DIAGNOdent device was determined, including sensitivity, specificity, overall accuracy, positive and negative predictive values, and receiver operating characteristic curve analysis. Chi-square test was conducted to compare the distribution of ICDAS-II and DIAGNOdent scores. Inter-observer agreement between assessors was evaluated using Cohen's kappa test. In the current study, DIAGNOdent had an overall accuracy of 84.45% with sensitivity and specificity of 87.58% and 96.87%, respectively, and +PV and -PV of 97.7% and 83.9%, respectively, when score 0 represented sound tooth surface, while scores 1 and 2 were considered clinically noncavitated carious lesions. Moreover, when only ICDAS score 1 was considered representing first visual change in enamel, DIAGNOdent had an accuracy of 74.15% with sensitivity and specificity of 83.53% and 90.62%, respectively, and +PV and -PV of 93% and 78.6%, respectively. In the present study, when only ICDAS score 2 was considered representing distinct visual change in enamel, DIAGNOdent had an accuracy of 100% with sensitivity and specificity of 100% and 100%, respectively, and +PV and -PV of 100% and 100%, respectively. The overall performance of DIAGNOdent was equivalent to the visual inspection using ICDAS-II. DIAGNOdent might be considered a useful adjunctive device for detection and monitoring development of noncavitated carious lesions on facial smooth surfaces.

Meta-Analysis of the Effectiveness of Teledentistry on Patients Satisfaction

Background: Preventive strategies of caries prevention, such as topical fluoridation or drinking water, have been effective in inhibiting the development of carious lesions. Teledentistry is an alternative service that combines dentistry with long-distance telecommunication technology for consultation and treatment planning that can be used for dental and oral health education to increase public awareness. The purpose of this study was to analyze the effectiveness of teledentistry on patient satisfaction. Subjects and Method: This study was a meta-analysis with the following PICO, population: patients. Intervention: teledentistry. Comparison: conventional (outpatient). Outcome: patients satisfaction. The articles used in this study were obtained from three databases, namely Google Scholar, Pubmed, and Science Direct. Keywords to search for articles are “teledentistry” OR “oral hygiene” AND “multimedia” OR “smartphone app” OR “online social media” AND “patient satisfaction”. The articles included are full text English with a randomized control trial study design from 2013 to 2023. The selection of articles was carried out using the PRISMA flow diagram. Articles were analyzed using the Review Manager 5.3 application. Results: A total of 9 case studies from the continents of Europe (Netherlands, Germany, Italy), North America (Pennsylvania), and Asia (India, Saudi Arabia, Iran) were selected for systematic review and meta-analysis. The results showed that 1.05 units of teledentistry increased patient satisfaction compared to not being given teledentistry. Statistical results (SMD = 1.05; 95% CI= 0.64 to 1.46; p &lt; 0.001). Conclusion: Teledentistry increased patient satisfaction Keywords: teledentistry, oral hygiene, online social media, patients satisfaction

ASSESSMENT OF THE PREVENTION MEASURES EFFECTIVENESS FOR THE DEVELOPMENT OF CARIOUS DENTAL LESIONS IN MILITARY PERSONNEL OF THE ARMED FORCES OF UKRAINE

Introduction. The prevalence and severity of diseases of the teeth and oral cavity are directly dependent on the level of dental care. The specific living conditions and combat activities of the personnel of the Armed Forces of Ukraine, associated with the characteristics of the military profession, influence the course of pathological processes of the dentofacial apparatus and require appropriate methods of prevention and treatment. The purpose of the research: to evaluate the effectiveness of measures to prevent the development of dental caries in military personnel of the Armed Forces of Ukraine. Materials and methods. To conduct the study, 348 military personnel of the Ternopil zonal department of the Military Law Enforcement Service (TZDMLES) were examined; they underwent a clinical examination in order to identify carious dental damage. The intensity of caries was determined according to the CFE index, and the acid resistance of enamel was studied using the TER test. After the initial examination, military personnel of all ages underwent complete sanitation of the oral cavity. According to indications, fissures were also opened and sealed. When enamel resistance was found to be decreased and initial forms of caries were present, patients underwent deep fluoridation of enamel and dentin. In order to optimize primary prevention measures for the development of major dental diseases for military personnel, we have developed an oral care program for the period of stay in the combat zone. Results. When studying the prevalence of the carious process during the initial examination among military personnel of the TZDMLES, it was found that the prevalence of the carious process in this category of people was high: from 83.08% in the age group of 20 to 25 years to 100% in the age groups of 36 to 40 and 41 to 45 years. Indicators of the intensity of the carious process tend to increase among men and women in all age groups. After 12 months of observation, a decrease in the increase in the “C” index and a significant increase in the acid resistance of enamel was noted in all age groups examined. Conclusions. When planning measures for the primary prevention of the development of carious lesions, it is necessary to take into account the peculiarities of the life of patients, which is especially reasonable for military personnel who are in the combat zone, and carry out preventive measures together with therapeutic ones in order to reduce the risk of developing major dental diseases and increase their combat effectiveness.

Incidence of white spot lesions and DMFT among patients treated with comprehensive orthodontics

Aim: The development of new caries lesions in patients undergoing orthodontic treatment is an undesirable side effect of treatment that arises because the fixed appliance tends to accumulate plaque. The aim of this study was to examine the white spot lesions (WSL), caries incidence, and decayed, missing, and filled teeth (DMFT) indices in patients with fixed orthodontic treatments. Methodology: The records of 150 patients treated at Necmettin Erbakan University Department of Orthodontics between 2018 and 2022 who met the study selection criteria were examined. Traditional methods and 2D color photographs were used to detect cavities. Pretreatment (T0) and post-treatment (T1) recordings were made. Results: Overall, 118 patients (78.6%) developed at least 1 new WSL during treatment and 49 patients (32.6%) developed active caries lesions. Increases in WSL, caries incidence, and the DMFT index were important during the treatment process. The length of treatment and the number of oral hygiene warnings were significantly associated with the development of new lesions. Conclusion: Individuals undergoing fixed orthodontic treatment have a significant incidence of WSLs and caries lesions. Patients and physicians should pay strict attention to this problem to effectively prevent caries occurrence during treatment. How to cite this article: Gönder HY, Yıldırım M, Metli ŞN. Incidence of white spot lesions and DMFT among patients treated with comprehensive orthodontics. Int Dent Res 2022;12(Suppl.1):85-9. https://doi.org/10.5577/intdentres.432 Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

A 5-year clinical follow-up of the efficacy of proximal sealing in high caries risk children

ObjectiveThe aim of the present study was to evaluate, after 5 years, the efficacy of proximal microinvasive sealing of permanent teeth on the risk for caries lesion development. MethodsChildren aged 8 to 10 y at baseline, at high caries risk, were studied. In the preventive (P) group the children had caries lesions on the distal surface of primary second molars (05d) but sound mesial surfaces of the approximating permanent first molars (6m). In the therapeutic (T) group the children had initial caries lesions on 6m that abutted lesions on 05d. Each child in the two groups had one 05d/6m pair. Using a split-mouth design, one 6m surface in each pair was randomly assigned to receive sealing while the other pair served as an unsealed control. ResultsOf the 61 children at baseline 42 could be blindly examined clinically and radiographically both at baseline and after 5 years. In the P group, 8 of 28 (28.6%) sealed and 15 of 28 (53.6 %) unsealed sound 6m surfaces had developed caries lesions (p = 0.04). In the T group, the progression of the carious lesions on 6m was observed in 4 of 14 sealed (28.6%) and 8 of 14 (57.1%) unsealed caries control surfaces (p = 0.29). Pooling the data from the two groups, the difference between sealed and non-sealed surfaces was significant (p = 0.013). ConclusionBoth preventive and therapeutic sealant to 6m adjacent to a lesion on 05d has effectiveness in caries reduction in high caries risk children Clinical SignificanceThe beneficial effect of sealing is observed for at least 5 years after a single sealant treatment.

Comparative Evaluation Of Clinical Performance Of Giomer Based And Hydrophilic Resin Based Pit And Fissure Sealant In Primary Molars: A Split Mouth Clinical Trial

Aim: The current in vivo study is done to compare the retention, marginal staining, marginal integrity, and development of new carious lesions between a hydrophilic resin-based sealant and a giomer-based pit and fissure sealant on primary molars.Study Design:180 primary molars from 45 participants are taken into consideration in this randomised clinical investigation. 90 primary molars were sealed with Beautisealant (Group 1) and the other 90 primary molars were sealed with Embrace Wet Bond sealant (Group 2). To evaluate the clinical performance Modified USPHS criteria will be used and applied immediately following sealant application, at 3, 6, and 12 months. The entire set of data was gathered, enteredinto MS Excel, and examined with SPSS 16.0. The parameters of clinical evaluation were compared using the Fisher's exact test and the Pearson Chi-Square test.Result: At the end of 12 months, 75.9% of group 2 primary molars still had sealants in place, compared to 26.2 percent of group 1, which is statistically significant (p.001). Conclusion: Hydrophilic sealants may be employed as efficient fissure sealants, particularly in children who are at high risk for tooth decay, overly salivate, are physically and intellectually challenged, have partially erupted molars, and for children enrolled in community care programs.