Cardiac Fibroma Research Articles

A Case of Transmural Lipoma of the Right Atrium

Primary cardiac tumors are a relatively rare disease. About 75% of primary cardiac tumors are benign. The most common histological type is myxoma, followed by cardiac fibroma, lipoma, etc. We report a case of a 53-year-old female patient admitted to the hospital due to "repeated palpitations and tightness of breath for 5 years, worsened for 2 days." Preoperative transthoracic echocardiography revealed a hypoechoic mass approximately 3.1 cm x 3.0 cm in size within the right atrium, suggesting an intracardiac mass: nature? Chest computed tomography (CT) indicated a fat-density nodule within the right atrium, with a larger cross-sectional size of about 3.0 cm x 2.5 cm, suggesting a lipoma. The patient underwent excision of the right atrial mass under cardiopulmonary bypass. Intraoperative transesophageal echocardiography (TEE) revealed a mass within the right atrium, closely connected to the atrial wall, with no signs of tricuspid valve obstruction. Exploration during surgery revealed a yellow, smooth-surfaced mass approximately 3.0 cm x 3.0 cm in size, penetrating the right atrial wall, from which the mass and an additional 2mm margin of the right atrial wall were completely excised. A suitable-sized bovine pericardial patch was used to repair the defect in the right atrial wall. Postoperative TEE showed the disappearance of the right atrial mass. The postoperative pathological result indicated a lipoma. Cardiac lipoma is a rare benign primary cardiac tumor. The common sites of occurrence of this tumor are the right atrium, left ventricle, and pericardium. Based on their location, cardiac lipomas can be divided into three types: subepicardial, intramyocardial, and subendocardial lipomas, with subendocardial lipomas being the most common, accounting for over 50% of primary cardiac lipomas. Clinical symptoms largely depend on the size and growth location of the tumor, and it is generally believed that most cardiac lipomas are asymptomatic. Symptomatic lipomas can be treated with curative surgical excision. Transmural lipomas of the right atrium are relatively rare, and such lipomas may affect adjacent structures both inside and outside the atrial wall. Although the lipoma in this case did not significantly affect valve function or blood flow, the patient experienced repeated symptoms of palpitations and tightness of breath. Despite being a benign tumor, the lipoma in this case exhibited transmural growth within the right atrium, showing a certain degree of invasiveness, making surgical excision an effective treatment method.

Gorlin Syndrome: A Comprehensive Evaluation of Skin Findings.

Although Gorlin syndrome has rich skin findings, there is limited information about their subtypes, features specific to this genodermatosis, and relationships with each other. The demographic characteristics as well as cutaneous and extracutaneous findings of consecutive Gorlin syndrome patients diagnosed during 23 years were evaluated retrospectively. The relationship between palmoplantar pitting and basal cell carcinoma (BCC) in this localization and the relationship between odontogenic keratocysts (OKCs) and epidermoid cysts were investigated. A total of 30 patients were diagnosed with Gorlin syndrome of whom 36.7% were children. BCC was the most common finding (90%) followed by OKCs (83.3%), skeletal system anomalies (76.7%), and palmoplantar pitting (76.7%). While classical BCC (63.3%) lesions were the predominant clinical subtype among all patients, acrochordon-like or small-sized papular BCCs were seen in 45.4% of pediatric patients. Three patients, 2 of whom were children, had BCC lesions in the palmoplantar region in association with palmoplantar pitting. Epidermoid cysts presenting clinically as solitary (n = 12) or a few nodules (n = 4) without punctum, located more commonly in acral areas (n = 10) were seen in 16 (53.3%) patients of whom 7 were children. Epidermoid cysts were seen in 60% of patients with OKCs, and the relationship between epidermoid cysts and OKCs was not statistically significant (P = .15). Extracutaneous tumors such as medulloblastoma (n = 3), cardiac fibroma (n = 1), and ameloblastoma (n = 1) were also recorded. The awareness of papular or acrochordon-like BCCs, palmoplantar BCCs, and acral epidermoid cysts without punctum may facilitate early diagnosis of Gorlin syndrome in children.

Kiosk 4Q-FA-05 - Utilizing Multi-modality Imaging in a Case of Cardiac Fibroma

Kiosk 4Q-FA-05 - Utilizing Multi-modality Imaging in a Case of Cardiac Fibroma

Cardiac fibroma as a cause of ventricular arrhythmias in childhood.

Cardiac fibroma as a cause of ventricular arrhythmias in childhood.

Cardiac fibroma as a cause of ventricular arrhythmias in childhood

Cardiac fibroma as a cause of ventricular arrhythmias in childhood

1053 An Insight into Cardiac Tumours Using Over 20 Years of Up-to-Date Historical Data.

Abstract Aim Cardiac tumours are uncommon and frequently incidental findings. The study aims at analysing the demographics, presentation, histological prevalence and outcomes for cardiac tumours over the past 21 years. Method An observational retrospective data analysis on an SCTS database of all patients undergoing cardiac surgery at 3 different centres in the UK was performed. Further data was collected through operative summaries, pathology reports and outpatient letters. Results 207 patients underwent an operation for a cardiac tumour between 2001 and 2022, 66.2% were female and 33.8% male. Mean age was 62 years (17- 86 years). 62.3% were urgent procedures, 21.3% elective and 16.4% emergencies. 44 patients presented with chest pain, 29 stroke, 18 palpitations/arrhythmias, 15 shortness of breath and 7 syncope. In 51 patients the finding was incidental. Average cardiopulmonary bypass time was 80 minutes, and the average cross clamp time was 52 minutes. In 80.2% of cases the left chamber was involved, 10.6% right atrium, 1% left ventricle and 0.5% right ventricle. The final pathological specimen was reported as myxoma in 80.2% of cases, fibroelastoma in 3.9%, thrombus in 7%, sarcoma in 2.9 % and 1% calcified mass. Other histologies included osteosarcoma, lymphoma, granulation tissue, infected mass, cardiac fibroma, and lipoma. In-hospital mortality was 1.5%. Conclusions Despite the rarity of cardiac tumours and the lack of presenting symptoms, the study demonstrated that surgical mortality is low and although the overwhelmingly the commonest histology was confirmed to be myxoma, sarcoma is also an important differential as are the other histologies, which may be surprising.

КРУПНАЯ ФИБРОМА ЛЕВОГО ЖЕЛУДОЧКА СЕРДЦА У РЕБЕНКА

Introduction. Fibroma is considered as benign solitary tumor, which is the second most common among primary heart tumors in children. It rarely starts to regresses, contributes to the formation of hemodynamic disorders and congestive heart failure, as well as life-threatening arrhythmias, and also can lead to the development of sudden death. Aim. Informing physicians about a rare cardiac fibroma in children on the example of a clinical case. Material and methods. Describing a clinical case of patient K., 7 months old, who was referred to the cardiac surgery department for a planned operation to remove a left ventricular mass, which was diagnosed prenatally at 32 weeks. Results and discussion. A dynamic observation was carried out, during which, according to echocardiography and magnetic resonance imaging, an increase in the tumor from 35x25 mm to 70x35 mm and the formation of mitral stenosis were noted. The average pressure gradient in the mitral valve increased from 2 to 11 mm Hg there was a limitation of the mobility of its valves. A partial resection of the tumor was performed. Morphological and immunohistochemical studies confirmed the diagnosis of fibroma. The postoperative period proceeded well. Conclusion. Cardiac fibromas in children, regardless to the clinical course of the disease, require long-term monitoring of patients with an electrocardiological study, echocardiography and magnetic resonance imaging method, and if there is a threat of complications, surgical removal of the tumor.

Characteristics of recurrent ventricular tachycardias after stereotactic body radiotherapy

Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): Grant project AZV NU20-02-00244 from the Ministry of Health of the Czech Republic and European Union's Horizon 2020 research and innovation program under grant agreement No 945119. Introduction Stereotactic body radiotherapy (SBRT) is a novel treatment for otherwise resistant ventricular tachycardias (VTs). Different mechanisms of SBRT for VT suppression were proposed that include radiation-induced fibrosis but also SBRT-triggered increase in myocardial conduction velocities without significant fibrotic changes. Purpose The study compared the morphologies and cycle lengths (CLs) of inducible VTs during re-do catheter ablation after SBRT with VTs before SBRT. Methods We investigated patients that underwent SBRT (a single session of 25 Gy) for refractory VT and subsequent electrophysiology study / reablation for recurrences of VTs. All inducible VTs were analysed concerning morphology and CL. Results A total of 9 patients (2 women, aged 60 ± 13 years) were included. Two patients had ischemic heart disease, six patients had nonischemic cardiomyopathy, and one had a cardiac fibroma. All patients were on chronic amiodarone treatment. The mean ejection fraction of the left ventricle was 35 ± 12%. The mean planning target volume for SBRT was 39 ± 21 ml. Electrophysiology study/reablation was performed at a mean interval of 8 months (interquartile range: 2-10months) after SBRT. A total of 23 and 27 distinct VT morphologies were inducible before and after SBRT, respectively. Twelve pairs of VTs (44%) were identified that had identical morphology before and after SBRT. The mean CL of these VT pairs decreased from 399 ± 98 ms to 472 ± 74 ms (P = 0.01) after SBRT. Overall, 15/27 of all VT morphologies induced after SBRT originated from the irradiated region. Conclusions Recurrent VTs after SBRT had commonly origin in the irradiated region. In pairwise comparison, the CL of VTs has prolonged after the SBRT. This suggests that SBRT results in radiation-induced fibrosis rather than an increase in conduction velocity.

Concurrent medulloblastoma and cardiac fibroma: a rare presentation of Gorlin-Goltz syndrome.

Gorlin-Goltz syndrome is a rare autosomal dominant disorder resulting from PTCH1 gene mutation and presents with variable clinical manifestations. The co-occurrence of medulloblastoma and cardiac fibroma in Gorlin-Goltz syndrome is extremely rare. The present article discusses a patient diagnosed with Gorlin-Goltz syndrome and concurrent medulloblastoma and cardiac fibroma. A 19-month-old boy transferred to our hospital after a radiological finding of posterior fossa lesion and hydrocephalus. A pericardial mass was noted after persistent arrhythmias. Both tumors were excised for definitive management. The histopathological sections were diagnostic of desmoplastic nodular medulloblastoma, WHO grade 4 and cardiac fibroma. Molecular and genetic investigations confirmed a pathogenic variant of PTCH1 gene, suggestive of autosomal dominant Gorlin-Goltz syndrome. Co-occurrence of medulloblastoma and cardiac fibroma is extremely rare and poses a management dilemma. Genetic counseling and antenatal screening are of utmost importance to early detect and manage patients with Gorlin-Goltz syndrome.

Cardiac Fibroma Presenting With Left Bundle Branch Block in an Adult With Gorlin Syndrome

Cardiac Fibroma Presenting With Left Bundle Branch Block in an Adult With Gorlin Syndrome

307 A CARDIAC MASS IN A PATIENT WITH GORLIN-GOLTZ SYNDROME: INCIDENTAL DIAGNOSIS OR SOMETHING TO LOOK FOR?

Abstract Aims Gorlin-Goltz syndrome or nevoid basal cell carcinoma syndrome (NBCCS) is a rare autosomal dominant, multisystem, tumor-predisposing disorder. The primary manifestation of NBCCS is the development of multiple basal cell carcinomas (BCCs) but is also associated with a variety of other benign and malignant tumors. Cardiac fibromas are increased in frequency in patients with NBCCS, developing in approximately 3 percent of affected individuals. They typically present in infancy. They are benign growths, and almost all develop within the ventricular myocardium. Although usually asymptomatic, they can result in impaired left ventricular function and conduction defects, necessitating resection. Methods and results we presented a case of a 59-years-old woman with a diagnosis of Gorlin-Goltz syndrome and no history of cardiovascular diseases who underwent a right knee arthroplasty in our hospital. After the surgery the patient was admitted to rehabilitation department. Electrocardiogram that showed sinusal rhythm with inverted T waves in lateral leads and a transthoracic echocardiography examination were performed. Echocardiography showed a large mass within the basal and middle segments of left ventricle lateral wall. Left ventricular ejection fraction was preserved. Cardiac magnetic resonance (CMR) revealed an intramyocardial mass with well-defined borders and several calcifications, hypointense on T1-weighted and T2-weighted images and delayed-contrast hyper-enhancement with hypoenhancing central cores. Based on these imaging features, the mass was suggestive of cardiac fibroma with calcifications. The patients was asymptomatic. Afterwards, a total body CT was performed to exclude other tumours in other sites. This case was discussed with cardiac surgeons and since the patient was asymptomatic with no conduction abnormalities or heart failure signs, urgent surgical intervention was excluded. The patient was discharged with a 3 months follow-up. Conclusion our case highlights the importance of echocardiography evaluation before surgery in patients with genetic syndrome like Gorlin-Goltz syndrome. Last guidelines published in 2021 recommend that all patients with NBCCS should be screened with a cardiac ultrasound and if cardiac symptoms occur in a patient with NBCCS, a cardiac ultrasound should be repeated to exclude a late-onset cardiac tumour. Furthermore, CMR plays an important role in characterizing cardiac masses and determining the management.

Unusual Cause of a Left Ventricular Mass in an Octogenarian with Metastatic Squamous Cell Lung Cancer

A computed tomography scan of the chest in an 83-year-old male patient with a history of metastatic squamous cell lung cancer revealed a mass localized to the left ventricle. Subsequent imaging revealed this to be an incidental cardiac fibroma.

Clinical Impact of Cardiac Fibromas

Cardiac fibromas are rare primary tumors that can cause significant morbidity and mortality. There has not been a large clinical case review since 1994. This study provides an updated analysis of clinical impact, thereby enhancing understanding, increasing awareness, and revealing important factors in the diagnosis and management of cardiac fibromas. A retrospective case series was conducted at a tertiary care institution by reviewing radiology, surgical and pathology archives (1964 to 2020). Cases were included if cardiac fibroma was diagnosed through imaging or pathology. Demographics, symptomatology, electrophysiologic data, radiographic findings, pathology, interventions, and outcomes were examined. A total of 26 patients with cardiac fibromas were identified, including 12 women. The median age was 20.5 years (0 days to 72 years). Symptoms included palpitations (commonly due to ventricular tachycardia, 31%), syncope (15%), angina (15%), heart failure (12%), emboli (4%), and murmur (27%). One patient had Gorlin syndrome. A total of 22 patients were diagnosed through imaging, 15 of whom were biopsy-confirmed. A total of 9 patients were initially observed. A total of 2 eventually had surgery, 1 was lost to follow-up, 3 were asymptomatic, 1 had heart failure and atrial fibrillation, and 1 had atrial fibrillation and tachy-brady syndrome, requiring ablation and pacemaker placement. A total of 19 underwent resection. A total of 4 required complex operations, 1 required a second resection, and 1 operative death occurred. In conclusion, cardiac fibromas primarily affect the pediatric population; however, this study demonstrates a significant prevalence in adults. Ventricular tachycardia is common, and multimodality imaging is diagnostically sensitive. Resection is largely successful in symptomatic patients. Surveillance may be appropriate for asymptomatic patients.

NFB-09. Treatment of cardiac fibroma in aPTCH1-mutated Gorlin syndrome with medulloblastoma

A 2,5-year-old girl presented vomiting episodes associated with severe motor delay, macrocephaly, and distal hypotonia. Brain MRI showed hydrocephalus and a non-metastatic lesion in the posterior fossa. A pre-operative ECG showed isodifasic T waves in leads V4R and V1, follow-up was recommended. Histology after gross total resection was consistent with Desmoplastic/Nodular Medulloblastoma. At chest X-rays a bifid rib was noted, leading to the diagnosis of Gorlin syndrome (GS; c.3306 + 1G>T in PTCH1). During chemotherapy, ventricular tachycardia (VT) occurred, requiring synchronized electrical cardioversion. An echocardiogram revealed an echogenic mass of the left ventricle free wall, but normal coronaries and ventricular function. Cardiac MRI (CMR) confirmed a 21x40x38mm mass, with eccentric development and intense homogeneous enhancement, indicative of cardiac fibroma (CF). A computed tomography excluded local calcifications. Therapy with amiodarone and beta-blocker was initiated. TREATMENT STRATEGY: priority to chemotherapy vs cardiac surgery; full-dose chemotherapy, preferring drugs with minor cardiotoxicity; administration in ICU under continuous vital parameters and ECG-monitoring. Other three VTs occurred during treatment or anesthesia, resolved after electrical cardioversion (unsuccessful attempts with i.v. adenosine and amiodarone). Lacking specific guidelines concerning CF in GS, a wait-and-see approach was preferred with close tumor follow-up and regular cardiological assessment (ECG, stress-test, Holter monitoring, CMR). No further arrhythmias were recorded in a 10-year-long follow-up and CMR confirmed CF stability. Medulloblastoma has never recurred. PTCH1 variants are rarely associated with medulloblastoma (<2%). Only 3–5% of GS present CF, responsible for arrhythmias in 32%. Being non-regressing, total surgical resection is usually performed (without recurrence), with a 27-year-long median survival. When surgery risk/benefit ratio is not favorable or the patient is paucisymptomatic, the treatment plan remains unclear; probably, a conservative approach under a strict cardiological follow-up can be reasonable. In young children with syndromic medulloblastoma, a routine echocardiogram should be performed to rule out CF.

A patient with recurrent strokes: multimodal imaging reveals two possible causes

Abstract An underlying cardio-embolic cause can be identified in a fifth of stroke patients. Cardiac tumors occur rarely in routine clinical practice but can cause severe complications such as heart failure, valve dysfunction, embolic events, or sudden cardiac death. Herein we present the case of a 67-year-old patient with a history of recurrent stroke in whom a patent foramen ovale (PFO) and a hypermobile structure attached to the aortic valve were diagnosed during a transesophageal examination. The structure was interpreted to be a papillary fibroelastoma. Coronary computed tomography angiography completed the diagnosis, helping to exclude a relevant coronary artery disease. The patient underwent an uneventful cardiac surgery with removal of the hypermobile structure and closure of the PFO. The histopathological analysis, however, was negative for elastin in the elastin stain, and thus the diagnosis of a cardiac fibroma was made. The case emphasizes the role of cardiovascular imaging in stroke patients as well as that of histopathological analysis.

Stereotactic body radiotherapy for refractory ventricular tachycardia: the overall czech experience

Abstract Funding Acknowledgements Type of funding sources: None. Background Catheter ablation (CA) is a well-established treatment strategy for the management of drug-refractory ventricular tachycardia (VT) in patients with structural heart disease. Stereotactic body radiotherapy (SBRT) was proposed recently as a treatment option for cases of failed CA. Purpose This study reports overall experience with the SBRT from two Czech centers. Methods Since 2014, we enrolled consecutive patients who underwent at least one prior CA for recurrent scar-related VT and had subsequent VT recurrences due to inaccessible substrate. Single-session SBRT for VT was performed without the use of general anesthesia or sedation. A dose of 25 Gy was delivered. Results The study investigated 33 patients (3 women) with a mean age of 66 ± 9 years. Underlying heart disease was ischemic (58%) and nonischemic (39%) cardiomyopathy; one patient had large cardiac fibroma. The mean left ventricular ejection fraction was 31 ± 8%. Seventy-six percent of patients were on amiodarone. Before SBRT, they underwent a median of 2 (IQR: 1-3; range: 1-5) CA that included epicardial access in 42% of patients. Following SBRT with a planned target volume of 42.6 ± 22.8 ml, the immediate effect was not observed in any patient, VT burden gradually decreased over weeks or months. Seventeen (52%) patients died (2 of them suddenly) during the mean follow up of 29 ± 23 months mainly due to the progression of heart failure (Figure 1). One patient died due to bleeding associated with esophagopericardial fistula that developed 9 months after SBRT. Overall, the number of DC shocks after a single procedure decreased significantly from 0.9 ± 1.9 per month in the period of 6 months before SBRT to 0.1 ± 0.3 per month in the period of 6-12 months after SBRT (P=0.008, Figure 2). However, 14 patients (42%) had to undergo additional CA due to VT recurrences at a mean interval of 13 ± 14 months after SBRT. Three patients underwent repeated SBRT (after 3, 29, and 38 months), which was successful in 2 of them. Conclusions SBRT in patients with refractory VT is feasible but the long-term mortality after the procedure is high and reflects mainly the severity of the underlying disease. The treatment effect of SBRT is delayed and additional CA is often necessary for VT suppression. At present, SBRT should be offered as only a bailout procedure for otherwise intractable VT.

Heart Transplant As Therapy For An Unresectable Recurrent Cardiac Fibroma

<h3>Introduction</h3> Cardiac fibromas (CF) have a reported incidence of 0.03-0.32% and have an excellent prognosis. Most cardiac tumors are found incidentally, and symptoms are related to location and size. Most CF are amenable to surgical removal, but some are deemed unresectable due to their size and/or invasion of vital cardiac structures that warrant heart transplants. <h3>Case Report</h3> 66-year-old male with a history of prior cardiac fibroma resection at age 13, followed by dual-chamber pacemaker insertion due to complete heart block and recent ventricular tachycardia ablation. He came to our facility for a second opinion regarding heart transplants because he was previously considered high-risk by another facility. Echo showed an EF of 55%, with CF noted on the anterior wall. Heart CT reported a LV anterior wall mass measuring 6 × 8.5 × 8.9 cm, markedly displacing the LAD and first diagonal with a non-hypermetabolic mass on PET scan. He was presented during our multidisciplinary team rounds; the decision was to proceed with biopsy of the left ventricular cardiac mass showing CF with abundant collagen in the stroma separating the tumor cells (Figure 1A), and the CF is composed of slender spindle cells admixed with undulant and wavy collagenized stroma. No nuclear pleomorphism or mitotic activity is present (Figure 1B). Postoperatively, the patient developed incessant VT requiring amiodarone and lidocaine. EP was consulted, and due to prior VT ablation and limited options, the patient was listed for an orthotopic heart transplant (OHT). He underwent successful OHT without complications. The explanted heart has a whorled, well-circumscribed, tan appearance mass measuring 14 × 10 × 9 cm involving the LV, the interventricular septum, and epicardium (Figure 2). <h3>Discussion</h3> Cardiac fibromas are connective tissue tumors that originate from fibroblasts, typically grossly well demarcated. CF are considered benign tumors, but they are well known to be the most common arrhythmogenic tumors than other cardiac tumors; It is essential that cardiologists be aware of CF presentation, diagnosis and treatment. Careful selection of potential candidates based on patient characteristics, type of tumor, and life-threatening complications for OHT by a multidisciplinary team is imperative in such complex cases. We report a case that required orthotopic heart transplantation due to incessant ventricular tachycardia secondary to recurrent unresectable fibroma.

Successful surgical resection plus surgical cryoablation for the treatment of a large left ventricular fibroma

Residual tumor mass after large cardiac fibroma resection carries long-term risk, but cryoablation is useful during surgery to remove such tissue. Here, we present a case of a large cardiac fibroma of the posterior wall of the left ventricle, discovered during long-term, episodic ventricular tachycardia. Resection with cryoablation completely removed the tumor, eliminating postoperative, distant ventricular arrhythmias.

Surgery for Primary Cardiac Tumors in Children: Successful Management of Large Fibromas.

BackgroundPediatric primary cardiac tumors (PCTs) are rare. Its clinical features and prognoses are not well defined. The management of asymptomatic patients with cardiac fibromas remains controversial.ObjectiveWe aimed to examine our experience in surgical resection of pediatric PCT, with specific focuses on the management of large fibromas.MethodsThis study included all the children who underwent surgical resection of PCT in our institution between December 2008 and June 2021. The last follow-up was performed between June 1st and August 26th, 2021. Kaplan–Meier method was used to estimate the postoperative survival, freedom from reoperation, event-free survival, and also related risk factors. The tumor volume and volume index (volume divided by body surface area) were measured for cardiac fibromas.ResultsOf the 39 patients with median operative age of 9.5 [interquartile range (IQR): 1.2–16.5] years, 35 (89.7%) had benign tumors (fibromas for 15, myxomas for 13, and others for 7). The length and volume of fibromas were independent of age and symptoms (Ps > 0.05). The fibroma volume index was negatively correlated with age (P = 0.039), with a mean value of 105 ± 70 ml/m2. Of the 15 patients with fibromas, 5 were asymptomatic, 4 received partial resection, 4 required transmural resection, and 4 presented postoperative left ventricular (LV) dysfunction (ejection fraction <50%). During the median follow-up period of 3.1 years and maximum of 12.5 years, adverse events included 2 early and 1 late death, 4 reoperations, 4 tumor recurrences, and 1 LV dysfunction lasting over one year. The 8-year survival, freedom from reoperation, and event-free survival rates were 90.4, 81.8, and 64.2%, respectively. Malignant tumor (P < 0.001) was associated with more adverse events. Transmural resection (P = 0.022) and larger tumor volume index than LV end-diastolic volume (P = 0.046) were risk factors for LV dysfunction following fibromas resection.ConclusionPediatric surgery for PCT can be performed with low mortalities and few adverse events. The size of cardiac fibroma in children relatively decreases with the increase of age. Larger tumor volume index than LV end-diastolic volume index and transmural tumor resection predicts postoperative LV dysfunction.

Cardiac fibroma: characteristics on echocardiography and cardiac magnetic resonance imaging.

Cardiac fibroma: characteristics on echocardiography and cardiac magnetic resonance imaging.