Large-scale towed system four-dimensional particle tracking velocimetry (4DPTV) implementation and measurements are presented for towing tank tests for a naval combatant 5415 ship model for straight ahead, static drift β = 10°, and pure sway βmax = 10° conditions. The results, for the first time, provide instantaneous volumetric flow field data around the ship model including near the hull surface, and a complete description of the sonar dome 3D unsteady vortex separation onset and progression due to the 4DPTV larger measurement volume and higher data rates in comparison with previous results using tomographic particle image velocimetry (TPIV); thereby, providing the essential data required for the assessment of current hybrid Reynolds-averaged Navier–Stokes/large eddy simulation turbulence modeling capabilities and guidance for the necessary modeling improvements. The 4DPTV system is summarized and compared with the previous TPIV, including the camera calibration procedures, trigger systems, and synchronization with the sway motion. Analysis procedures, including data reduction procedures and the 3D vortex core detection and voxel labeling techniques, are described. The identification of the complex vortex separations and breakdown is aided using complementary detached eddy simulations. The vortex–vortex interaction process is visualized from instantaneous volumetric datasets. The pros and cons of the 4DPTV vs TPIV, the comparison between the second- and third-generation vortex visualization technique, and the statistical convergence error analysis of sonar dome port vortex for β = 10° are discussed. Plans for increased spatial resolution of the 4DPTV system and additional data reduction techniques for detailed turbulence analysis are also discussed.