Acceptable Candidates Research Articles

Artificial Intelligence in Drug Identification and Validation: A Scoping Review.

The end-to-end process in the discovery of drugs involves therapeutic candidate identification, validation of identified targets, identification of hit compound series, lead identification and optimization, characterization, and formulation and development. The process is lengthy, expensive, tedious, and inefficient, with a large attrition rate for novel drug discovery. Today, the pharmaceutical industry is focused on improving the drug discovery process. Finding and selecting acceptable drug candidates effectively can significantly impact the price and profitability of new medications. Aside from the cost, there is a need to reduce the end-to-end process time, limiting the number of experiments at various stages. To achieve this, artificial intelligence (AI) has been utilized at various stages of drug discovery. The present study aims to identify the recent work that has developed AI-based models at various stages of drug discovery, identify the stages that need more concern, present the taxonomy of AI methods in drug discovery, and provide research opportunities. From January 2016 to September 1, 2023, the study identified all publications that were cited in the electronic databases including Scopus, NCBI PubMed, MEDLINE, Anthropology Plus, Embase, APA PsycInfo, SOCIndex, and CINAHL. Utilising a standardized form, data were extracted, and presented possible research prospects based on the analysis of the extracted data.

Application of Game Theory in the Nigerian Electoral System

In this paper, we carry out a study on the application of game theory in the Nigerian electoral system. The data for the study was collected from the official publication of INEC results for six major political parties in the February 25th, 2023 presidential election in Nigeria. In the competitive game, each political party and INEC used mixed strategies in the game. The political parties compete for the electorates’ vote while INEC regulates the game. INEC has six strategies and political parties also have six strategies which they apply in various proportions to outweigh the other. Therefore, for any of the political parties to be successful in the election, she must apply: party structure up to 19.54%; manifesto up to 20.18%; campaign up to 19.05%; people’s perception of the political party up to 20.26%; vote from electorate up to 19.54% and acceptable candidate up to 1.43% of the time respectively. For INEC to effectively perform her statutory responsibility, she must apply: electoral law up to 18.71%; electoral guidelines up to 19.99%; prosecuting electoral offenders up to 16.87%; cancelling elections up to 23.14%; inconclusive elections up to 19.19%; declaration of results up to 2.10% of the time respectively and the value of the game was 1.5337.

Retransplantation in Living Donor Liver Transplantation.

The need for retransplantation after living donor liver transplantation can occur early, mainly because of technical difficulties such as hepatic artery thrombosis or as a result of early allograft dysfunction as a symptom of small-for-size syndrome. Patients with autoimmune diseases may develop progressive graft failure from recurrent disease. The ethics of retransplantation can be complicated by the cause of the initial liver disease, which may be self-inflicted or the outcome of malignancy. This is especially true in countries without the availability of deceased donors for salvage, and a second living donor would be needed. Nevertheless, patients who experience early or late graft failure should be considered for retransplant if they are deemed acceptable candidates. When a living donor is required for retransplant, the equipoise between donor risk and autonomy and recipient outcome should be considered.

Abstract IA002: Management of newly diagnosed endometrial cancers and molecular classification

Abstract In the past 50 years, the treatment of this cancer has evolved from a regimen of preoperative radiation therapy followed by hysterectomy, to individualized management consisting of surgical treatment with or without additional therapy depending on whether various risk factors are identified. After the diagnosis of endometrial carcinoma has been histologically confirmed, uterine and extrauterine risk factors affect the probability of retroperitoneal lymph node involvement and subsequent survival. Surgical staging is a critical component for the proper diagnosis and management of all endometrial carcinomas. FIGO stage is the most powerful predictor of prognosis. Surgical staging is feasible by minimally invasive techniques. Patients with significant medical comorbidities who are not acceptable candidates for surgery may be managed by alternative means. Women with EC are diagnosed under the age of 40 may be eligibile for nonoperative management if there is no clear evidence of myometrial invasion. As the contemporary management of EC continues to evolve, and the indications for lymph node dissection remain controversial. Minimally invasive management of EC has increasingly been integrated into standard practice. In 2006, The Cancer Genome Atlas (TCGA) began with studies in glioblastoma and high-grade serous ovarian cancer. The National Institutes of Health committed major resources to TCGA to collect and characterize the genomic landscape of more than 20 cancer types. In 2013, TCGA published findings for endometrial cancers. Only serous and endometrioid subtypes were accrued in the endometrial cancer project. TCGA has reclassified endometrioid and serous endometrial cancers in four broad categories using comprehensive genomic approaches. One-third of the cancers is characterized by microsatellite instability (MSI) and associated hyper-mutation. The cancers without MSI can be further separated into two groups. Serous cases with extensive DNA copy number alterations and genomic instability comprise one group, and endometrioid cases with few or only focal copy number alterations comprise the other. A smaller fourth sub-group contains samples with very high mutation rates and is characterized by mutations in POLE. Molecular features can be distinctly overlaid onto these four sub-classifications, and each have important clinical implications that are currently being used in both clinical practice and clinical trial design. In this educational presentation, we will discuss the management of newly diagnosed endometrial cancers, review the molecular classification of endometrial cancers, and identify approaches that incorporate these findings into clinical care and clinical trial design. Citation Format: Douglas A. Levine. Management of newly diagnosed endometrial cancers and molecular classification [abstract]. In: Proceedings of the AACR Special Conference on Endometrial Cancer: Transforming Care through Science; 2023 Nov 16-18; Boston, Massachusetts. Philadelphia (PA): AACR; Clin Cancer Res 2024;30(5_Suppl):Abstract nr IA002.

РАЗРАБОТКА СИСТЕМЫ ОЦЕНКИ КАЧЕСТВА РАБОТЫ ВОДИТЕЛЕЙ ТАКСОМОТОРНЫХ АВТОТРАНСПОРТНЫХ СРЕДСТВ

To improve the quality of the organization of transportation activities in the field of taxi passenger transportation, it is necessary to take a responsible approach to the selection and subsequent employment of a motor vehicle driver. The article suggests indicators that can fully characterize the driver of a motor vehicle in terms of safety of vehicle operation, professionalism and technical literacy, decency and accuracy, politeness. Depending on the priorities of the employer, represented by the management of a taxi company or a taxi aggregator, you can choose the most acceptable candidate for the position of a taxi driver or a partner of a contractor engaged in passenger automobile transportation. The unified database of taxi drivers created subsequently, containing individual performance indicators of their work, has a number of advantages for both taxi drivers and employers, allowing some, depending on their work efficiency, to claim higher wages for their work, and others the opportunity to reduce the cost of operating vehicles and improve the culture of taxi trucking.

Bionic Fish-Shaped Triboelectric-Electromagnetic Hybrid Generator via a Two-Stage Swing Mechanism for Water Flow Energy Harvesting and Condition Monitoring.

The water flow energy of rivers is an important renewable and clean energy that plays a vital role in human life but is challenging to harvest at low flow velocity. This work proposes a bionic fish-shaped triboelectric-electromagnetic hybrid generator (BF-TEHG) via a two-stage swing mechanism for harvesting water flow energy. It is designed to simulate the shape of fish, effectively improving its ability to utilize low-velocity water flow energy and enabling it to operate at a minimum flow rate of 0.24 m/s. Furthermore, the impact of motion parameters on electrical performance is studied. The triboelectric and electromagnetic power-generation units can generate peak powers of 0.55 and 0.34 mW in the simulated river environments with a flow velocity of 0.98 m/s. In applications, after being immersed in water for 40 days, the BF-TEHG maintains its electrical performance without reduction, indicating excellent water immersion durability. Therefore, this work proposes an efficient strategy to harvest low-velocity water flow energy and provides an acceptable candidate for monitoring water flow conditions.

Abstract 14806: Rate of In-Hospital Initiation of SGLT2 Inhibitors Remains Low Despite Reduction in Rate of 30-Day Readmission From Heart Failure Exacerbation

Introduction: Heart failure (HF) management guidelines recommend starting SGLT-2 inhibitors (SGLT2i) for symptomatic HF to reduce rates of HF hospitalization and cardiovascular mortality. However, in-hospital initiation of SGLT2i for titration has yet to be strongly recommended. In this study, we sought to evaluate the effect of in-hospital initiation of SGLT2i on the rate of 30-day HF-related readmission from an index admission for HF exacerbation at the University of Vermont Medical Center (UVMMC). Hypothesis: Patients who are admitted for an HF exacerbation who are discharged on SGLT2i from their index admission are less likely to be readmitted from an HF-related cause within 30 days of discharge compared to patients who are not started on an SGLT2i, though a minority of eligible patients will be started on SGLT2i during this time. Aims: The aims of this study are to 1) compare 30-day HF-related readmission rates between patients discharged on SGLT2i during their index admission, and patients not on SGLT2i, and 2) describe the proportion of patients not currently on SGLT2i who appear to be eligible. Methods: We conducted a chart review of 122 patients admitted to UVMMC from July to December 2022 with an HF exacerbation. We recorded patient and index admission descriptors, including ejection fraction, other GDMT (BB, RAASi, MRA), comorbidities, demographics, and admission duration. We then determined if 1) an HF-related readmission occurred within 30 days, 2) the patient was an acceptable candidate for SGLT2i, and 3) SGLT2i was present on discharge. Results: Among 122 patients admitted with an HF exacerbation at UVMMC, the 30-day HF-related readmission rate of patients discharged on SGLT2i was 3.7%, compared to 8.5% for patients not started on SGLT2i. Of these 122 patients, while 116 (95.1%) were acceptable candidates for SGLT2i, only 27 (23.3%) were discharged on SGLT2i, with 8 more (6.9%) eventually started on SGLT2i. Conclusions: Our review affirms guidelines that recommend starting SGLT2i in patients with symptomatic HF to reduce rates of HF hospitalization. Despite these guidelines, adoption rates remain low due to a variety of factors. Improving in-hospital SGLT2i initiation rates would benefit HF patients and the healthcare systems that support them.

Novel magnetic nanocomposites BiFeO3/Cu(BDC) for efficient dye removal

In this study, bismuth ferrite nanoparticles and metal-organic framework, Cu(BDC), were prepared by microwave-assisted combustion in solid state and ultrasound-assisted method, respectively. To enhance the properties of bismuth ferrite nanoparticles and Cu(BDC), we form them as their composite through microwave and ultrasonic probe strategies. Various analyses, including FT-IR, XRD, SEM, DRS, VSM, and so on, were applied to verify the synthesis accuracy. Then, the catalytic performances of the nanoparticles and the as-prepared nanocomposites were evaluated through photocatalytic degradation of methyl orange. Furthermore, the adsorption capacity of the as-synthesized materials was assessed toward the Congo red removal from wastewater. All the results prove that the proposed nanocomposite can be an acceptable candidate for eliminating contaminants from wastewater. The electrochemical properties of bismuth ferrite, BiFeO3/Cu(BDC) nanocomposite 1, and BiFeO3/Cu(BDC) nanocomposite 2 have been studied by cyclic voltammetry.

Influence of Daily Aerobic Exercise Duration on Phase 2 Cardiac Rehabilitation at a Rehabilitation Hospital and Health-Related Quality of Life After Discharge.

Phase 2 in-patient cardiac rehabilitation (CR) at a rehabilitation hospital is now added the medical service fees in Japan and in light of the recent reimbursement for CR, a study needed to be performed to determine exertional exercise on its effectiveness and benefits to patients. We examined the effects of daily aerobic exercise duration on health-related quality of life (HR-QoL) at 6 months after discharge from phase 2 CR. Of the 54 consecutive cardiovascular disease patients admitted to a rehabilitation hospital after acute care, 43 were considered acceptable candidates for enrollment according to predetermined inclusion and exclusion criteria. Of these, 40 patients completed study requirements, including return of a questionnaire on HR-QoL survey 6 months after discharge. The primary outcome was HR-QoL as evaluated using the EuroQol five-dimension five-level (EQ-5D-5L). Two multiple regression models were constructed to assess the influences of daily aerobic exercise duration (content of rehabilitation) and other clinicodemographic variables assessed during acute care (model 1) or at transfer from acute care to a rehabilitation hospital (model 2). Both model 1, which included age, Barthel index of daily function before hospitalization, and daily aerobic exercise duration in the rehabilitation hospital (R2 = 0.553, P < 0.001), and model 2, which included New York Heart Association functional classification at transfer, Charlson comorbidity index at transfer, and daily aerobic exercise duration (R2 = 0.336, P = 0.002) identified aerobic exercise duration as a significant independent factor influencing HR-QoL at 6 months post-discharge (model 1: P = 0.041; model 2: P = 0.010). Enhanced daily aerobic exercise content during phase 2 in-hospital CR can significantly improve longer-term HR-QoL among cardiovascular disease patients independently of other clinicodemographic factors, including age, activities of daily living before treatment, and baseline condition at rehabilitation onset. These findings, that in the small sample size, support the continued expansion of phase 2 CR at a rehabilitation hospital in Japan.

Pain Education and Knowledge (PEAK) Consensus Guidelines for Neuromodulation: A Proposal for Standardization in Fellowship and Training Programs.

The need to be competent in neuromodulation is and should be a prerequisite prior to completing a fellowship in interventional pain medicine. Unfortunately, many programs lack acceptable candidates for these advanced therapies, and fellows may not receive adequate exposure to neuromodulation procedures. The American Society of Pain and Neuroscience (ASPN) desires to create a consensus of experts to set a minimum standard of competence for neurostimulation procedures, including spinal cord stimulation (SCS), dorsal root ganglion stimulation (DRG-S), and peripheral nerve stimulation (PNS). The executive board of ASPN accepted nominations for colleagues with excellence in the subject matter of neuromodulation and physician education. This diverse group used peer-reviewed literature and, based on grading of evidence and expert opinion, developed critical consensus guides for training that all accredited fellowship programs should adopt. For each consensus point, transparency and recusal were used to eliminate bias, and an author was nominated for evidence grading oversight and bias control. Pain Education and Knowledge (PEAK) Consensus Guidelines for Neuromodulation sets a standard for neuromodulation training in pain fellowship training programs. The consensus panel has determined several recommendations to improve care in the United States for patients undergoing neuromodulation. As neuromodulation training in the United States has evolved dramatically, these therapies have become ubiquitous in pain medicine. Unfortunately, fellowship programs and the Accreditation Council for Graduate Medical Education (ACGME) pain program requirements have not progressed training to match the demands of modern advancements. PEAK sets a new standard for fellowship training and presents thirteen practice areas vital for physician competence in neuromodulation.

Twelve tips for improving the quality of assessor judgements in senior medical student clinical assessments

Assessment of senior medical students is usually calibrated at the level of achieving expected learning outcomes for graduation. Recent research reveals that clinical assessors often balance two slightly different perspectives on this benchmark. The first is the formal learning outcomes at graduation, ideally as part of a systematic, program-wide assessment approach that measures learning achievement, while the second is consideration of the candidate’s contribution to safe care and readiness for practice as a junior doctor. The second is more intuitive to the workplace, based on experience working with junior doctors. This perspective may enhance authenticity in assessment decisions made in OSCEs and work-based assessments to better align judgements and feedback with professional expectations that will guide senior medical students and junior doctors’ future career development. Modern assessment practices should include consideration of qualitative as well as quantitative information, overtly including perspectives of patients, employers, and regulators. This article presents 12 tips for how medical education faculty might support clinical assessors by capturing workplace expectations of first year medical graduates and develop graduate assessments based on a shared heuristic of ‘work-readiness’. Peer-to-peer assessor interaction should be facilitated to achieve correct calibration that ‘merges’ the differing perspectives to produce a shared construct of an acceptable candidate.

Suppressing oxygen redox in layered oxide cathode of sodium-ion batteries with ribbon superstructure and solid-solution behavior

Sodium-ion batteries (SIBs) are proved as one of the most acceptable candidates for replacing lithium-ion batteries in some fields by virtue of a similar “rocking chair” mechanism and the abundance of sodium. The voltage, rate performance, and energy density of these batteries are mainly determined by the cathodes. Hence, a Li-Ni-Co co-substituted P2-Na0.67[Li0.1(Mn0.7Ni0.2Co0.1)0.9]O2 (NLMNC) with ribbon superstructure is prepared with the aim of multi-ion synergistic modification. Owing to the addition of Ni and Co, the Jahn–Teller distortion of Mn can be suppressed corresponding with the improved structural stability, and a little bit of oxygen redox activities is triggered. When with the substitution of 10% Li, the X-ray diffraction (XRD) peaks of NLMNC show the ribbon superstructure at about 21° and 22°. The smooth charge/discharge profiles of the NLMNC cathode exhibit the solid-solution reaction. In addition, the platform at high voltage disappears corresponding with the existing oxygen redox activities being suppressed which may be related to the ribbon superstructure and the promotion of the Ni redox. Such NLMNC cathode can deliver a reversible discharge capacity of 123.5 mA h g–1 at 10 mA g–1. Even if the current density increases to 500 mA g–1, a reversible discharge capacity of 112.8 mA h g–1 still can be obtained. The distinguished cycling stability is related to the reversible migration of Li+ between the metal oxide layer and the interlayer and low volume change during cycling. It is also needing to be mentioned that the capacity retention of NLMNC cathode is about 94.4% (based on the highest discharge capacity) after 100 cycles. This work presents an effective route to develop high-performance cathodes for SIBs.

Beam pattern control for graphene-based patch array antenna with radio-over-fiber systems by using modulation instability phenomenon

This paper presents a beam control system for a graphene-based phased array antenna (PAA) using the proposed radio-over-fiber (RoF) in the THz and sub-THz bands. The generated pulses are modulated by the Mach-Zehnder modulator (MZM) and, by using the special design of the fiber under modulation instability (MI), can be amplified at the sideband of the carrier. Finally, changing the length of the compensating fiber in the bit-control system makes it possible to control the PAA beam pattern. Improving the bias voltage (V π ) of the MZM, simplicity of the RoF system structure, and increasing the spontaneous gain caused by the MI phenomenon are the advantages of the proposed system. Therefore, it is an acceptable candidate for the beam control applications system. Also, the patch antenna is based on graphene and has a new structure. This antenna consists of radiation patches in an octagonal shape and a microstrip feed line. The antenna operates with appropriate radiation features, with gains of 12 dB and returns losses of less than -10 dB at 700 GHz bandwidth. All simulations are performed using the CST Microwave Studio and the Optiwave software.

Potential medicinal plants to combat viral infections: A way forward to environmental biotechnology

The viral diseases encouraged scientific community to evaluate the natural antiviral bioactive components rather than protease inhibitors, harmful organic molecules or nucleic acid analogues. For this purpose, medicinal plants have been gaining tremendous importance in the field of attenuating the various kinds of infectious and non-infectious diseases. Most of the commonly used medicines contains the bioactive components/phytoconstituents that are generally extracted from medicinal plants. Moreover, the medicinal plants offer many advantages for the recovery applications of infectious disease especially in viral infections including HIV-1, HIV-2, Enterovirus, Japanese Encephalitis Virus, Hepatitis B virus, Herpes Virus, Respiratory syncytial virus, Chandipura virus and Influenza A/H1N1. Considering the lack of acceptable drug candidates and the growing antimicrobial resistance to existing drug molecules for many emerging viral diseases, medicinal plants may offer best platform to develop sustainable/efficient/economic alternatives against viral infections. In this regard, for exploring and analyzing large volume of scientific data, bibliometric analysis was done using VOS Viewer shedding light on the emerging areas in the field of medicinal plants and their antiviral activity. This review covers most of the plant species that have some novel bioactive compound like gnidicin, gniditrin, rutin, apigenin, quercetin, kaempferol, curcumin, tannin and oleuropin which showed high efficacy to inhibit the several disease causing virus and their mechanism of action in HIV, Covid-19, HBV and RSV were discussed. Moreover, it also delves the in-depth mechanism of medicinal with challenges and future prospective. Therefore, this work delves the key role of environment in the biological field.

Effect of Shorea robusta resin extract in 3-nitropropionic acid-induced Huntington's disease symptoms in Sprague-Dawley rats.

Huntington's disease (HD) is a neurodegenerative disease characterized by neuronal death in the striatum. Asiatic acid is an active component of Shorea robusta (Dipterocarpaceae) plants with neuroprotective activity and is considered an acceptable therapeutic candidate for different neurodegenerative diseases. In the present study, the beneficial pharmacological action of Shorea robusta resin extract (SRRE) was assessed in 3-nitropropionic acid (3-NP)-induced HD in rats. The neuroprotective effect of SRRE (285.7 and 666.7 mg/kg, p.o., 14 days) was studied in 3-NP (10 mg/kg)-induced rats by measuring body weight, behavioral parameters including neurological scoring, motor coordination, spatial memory, and depression-like behavior, neuro-biochemical parameters (gamma-aminobutyric acid and acetylcholinesterase), and oxidative stress parameter in the brain. Histopathology of the rat's brain was also studied. SRRE treatment (285.7 mg/kg and 666.7 mg/kg) substantially restored body weight, motor coordination, and mitochondrial enzyme complex I function and improved memory impairment as compared to 3-NP-treated rats. Furthermore, SRRE treatment significantly restored the antioxidant enzyme activity in brain tissue and ameliorated the histopathological changes induced by 3-NP. The neuroprotective effect of SRRE on 3-NP-induced HD in rats was mediated by a reduction in oxidative stress which may favor the usefulness of Shorea robusta in HD.

Evaluation of the effects of alumina nanowire on 3D printed polycaprolactone / magnetic mesoporous bioactive glass scaffold for bone tissue engineering applications

In bone tissue engineering, it is necessary to choose appropriate and efficient biomaterial for higher efficiency of the scaffold. This study used the sol-gel method to synthesise magnetic mesoporous bioactive glass (MMBG). Then, different percentage of alumina nanowire (Al2O3) were mechanically added to MMBG. After that, it was mixed with polycaprolactone (PCL) polymeric solution, and finally, the samples were printed using by Liquid Deposition Modeling (LDM) method. The results of X-ray diffraction (XRD), zeta potential, Bruner-Emmt-Teller (BET) and Vibrating Sample Magnetometer (VSM) analysis illustrated that the synthesised bioactive glass nanoparticles have a mesoporous structure with paramagnetic properties. The SEM results of the 3D printed scaffolds illustrated homogeneous structures with interconnected pores. The scaffolds' mechanical strength and contact angle were significantly improved by adding Al2O3 up to 5 wt %. Furthermore, the degradation and bioactivity of the scaffolds improved with the presence of alumina nanowires. Cell viability and proliferation of MG-63 cells and alkaline phosphatase (ALP) activity significantly increased in PCL/MMBG/5Al2O3 scaffolds compared to PCL and PCL/MMBG scaffolds. Results obtained from this study demonstrated that the 3D printed PCL/MMBG/5Al2O3 scaffold could be an acceptable candidate for bone tissue engineering applications.

And Finally: Matters of Life and Death

And Finally: Matters of Life and Death

Matching Candidates to Culture: How Assessments of Organisational Fit Shape the Hiring Process

Organisational fit represents a crucial criterion in the hiring process. This article aims to understand how employers and external recruitment consultants define and apply organisational fit in professional labour markets, such as engineering, marketing and finance. It also investigates how the use of organisational fit in hiring can lead to social bias within these labour markets. It relies on semi-structured interviews with 47 external recruitment consultants who assist employers in these sectors. The article draws on Relational Inequality Theory to demonstrate how hiring managers and consultants use organisational fit to create and justify boundaries between acceptable and unacceptable candidates. Claim-making supports the rationalisation and legitimisation in the exclusion of groups of candidates. The article critically informs human resource management, business and psychology literature that perceive organisational fit as a largely benign criterion for recruitment. It also extends sociological and critical management literature by delineating three main exclusionary mechanisms in matching candidates for organisational fit.

Translating legal formulae: a corpus-driven approach

Fixed lexical or syntactical expressions and formulae hallmark legal language. They serve both linguistic and legal purposes, and should be rendered accordingly in a target language and legal system. Most of the times, however, formulaic expressions are translated by resorting to calques, false cognates, or phrases that are uncommon in the target legal language (and legal system). This paper is aimed at exploring how and if corpus analysis can dispel doubts and help find acceptable translation candidates. As there are currently no publicly available legal corpora addressing corporate documents such as contracts and agreements, this paper wishes to bridge this gap by building and relying on an ad hoc corpus of authentic agreements written in English as a first language according to the laws of England and Wales. In this way, corpus evidence can help find equivalents and, possibly, address recurrent mistranslations from Italian into English. During the corpus analysis process, the paper shows and discusses search queries and how equivalents can be obtained. At the same time, it questions dictionary entries. The paper findings highlight that the consultation of the ad hoc corpus allows to find acceptable translations of Italian legal formulae and address recurrent mistranslations. English formulaic expressions, in fact, can be rendered satisfactorily thanks to the possibility of noticing word usages in context, keywords in contexts and collocations. Further research can encompass a wider variety of formulae and/or legal documents so that scholars and translators can be equipped with useful reference tools.

Use of Urban Open-waterbody to Enhance Fish Production through Cage Culture

The purpose of the experiment was to examine the effect of cage fish culture on the growth and production performances of Shing (Heteropneustes fossilis), Pabda (Ompok pabda) and Gulsha (Mystus cavasius). The stocking density for each fish species was 100 fish/m3. Cages with Shing, Pabda and Gulsha were treated as T1, T2 and T3, respectively. Fishes were fed with artificial diet at the rate of 5-10% of body weight. The experiment was carried out in cages in the Beel from June to November 2019. The study revealed that water quality parameters were not varied significantly (p &gt; 0.05) among the treatments. The growth and production performance were significantly (p &lt; 0.05) higher for Pabda cage culture followed by Gulsha and Shing cultures in cages. Therefore, the total net return (BDT 17,028) and benefit cost ratio (2.48) were significantly (p &lt; 0.05) higher for Pabda fish considering cost benefit analysis. It was concluded that, among the three different fish species, high-valued Pabda is highly acceptable candidate for cage farming in Belai Beel area and cage farming in urban open waterbodies is a promising approach to increase the total fish production to improve the social and economic status of fish farmers.