Immunotherapy has been one of the hot topics in the field of colorectal cancer research in recent years. Patients with microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) are the main beneficiaries of immunotherapy. The respon... Read More
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[Neoadjuvant immunotherapy for colorectal cancer].
- Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery
- VOL. 26
on Jan 25, 2023
- Neoadjuvant Immunotherapy
- MSS Colorectal Cancer
- Colorectal Cancer
- MSI-H
- Immunotherapy In Combination
- Rectal Cancer Patients
- More +
Top advances of the year: Hepatobiliary cancers.
- Cancer
on Jan 24, 2023
- Cancer Research
- Hepatobiliary Cancer
- Disease Course
- Advances In Research
- Commentary Reviews
- Checkpoint Inhibitors
- More +
This commentary reviews top advances in hepatobiliary cancer research in 2021-2022, focusing on leveraging immunotherapeutics in combination with other therapies earlier in the disease course and targeted to patient's individualized biomarkers that m... Read More
Urine biomarkers in cancer detection: A systematic review of preanalytical parameters and applied methods
- International Journal of Cancer
on Jan 22, 2023
- Preanalytical Parameters
- Cancer Detection
- Biomarkers In Cancer Detection
- Cancer Types
- Analyte Class
- Protocols For Sample Processing
- More +
The aim of this review was to explore the status of urine sampling as a liquid biopsy for noninvasive cancer research by reviewing used preanalytical parameters and protocols. We searched two main health sciences databases, PubMed and Web of Science.... Read More
Artificial Neural Networks in Lung Cancer Research: A Narrative Review
- Journal of Clinical Medicine
on Jan 22, 2023
- Cancer Research
- Lung Cancer Research
- Artificial Neural Networks
- Networks In Research
- Narrative Review
- Lung Cancer
- More +
Mechanisms of cancer-killing by quercetin; A review on cell death mechanisms
- Anti-Cancer Agents in Medicinal Chemistry
- VOL. 23
on Jan 20, 2023
- Cancer Research
- Suppression Of Tumor Suppressor Genes
- Cell Death Mechanisms
- Activity Of Tumor Suppressor Genes
- Autophagic Cell Death
- Multidrug Resistance Mechanisms
- More +
Abstract: Cancer drug resistance has always been a serious issue regarding cancer research and therapy. Different cancers undergo different mutations, which may cause suppression of tumor suppressor genes, inhibition of apoptosis, stimulation of dru... Read More
Mexican Colorectal Cancer Research Consortium (MEX-CCRC): Etiology, Diagnosis/Prognosis, and Innovative Therapies
- International Journal of Molecular Sciences
on Jan 20, 2023
- Cancer Research
- Innovative Therapies
- Cancer Research Consortium
- Research Consortium
- Colorectal Cancer
Bodywide ecological interventions on cancer
- Nature Medicine
on Jan 19, 2023
- Cancer Research
- Therapeutic Response Of Patients
- Gut Microbiota
- Tumor Microenvironment
- Quality Of Life
- Trajectory Of Disease
- More +
Historically, cancer research and therapy have focused on malignant cells and their tumor microenvironment. However, the vascular, lymphatic and nervous systems establish long-range communication between the tumor and the host. This communication is ... Read More
Identification of microRNA Signatures in Peripheral Blood of Young Women as Potential Biomarkers for Metal Allergy
- Biomedicines
- VOL. 11
on Jan 19, 2023
- Signatures In Peripheral Blood
- Identification Of microRNA Signatures
- Peripheral Blood miRNAs
- Target miRNA Expression
- Patch Test
- RT-PCR
- More +
MicroRNA (miRNA) is a short (19–24 nucleotide) endogenous non-protein RNA that exists in the body and controls the translation process from genes to proteins. It has become useful as a diagnostic tool and a potential treatment target in cancer resear... Read More
Effects of a Sound Intervention on Physical and Emotional Well-Being in Patients with Cancer: A Prospective Randomized Trial
- Oncology Research and Treatment
- VOL. 46
on Jan 19, 2023
- Sound Intervention
- EORTC
- Emotional Well-being In Patients
- FoP
- VAS Fatigue
- Well-being In Outpatients
- More +
Aim: Cancer remains a disease with a significant impact on morbidity and mortality but also on quality of life. This prospective randomized pilot study investigated the effects of a sound intervention on physical and emotional well-being in outpatien... Read More
An evaluation of the Index4 tool for chemotherapy toxicity prediction in cancer patients older than 70\xa0years old
- Scientific Reports
- VOL. 13
on Jan 19, 2023
- CARG
- Chemotherapy Discontinuation
- Aging Research Group
- Geriatric Cancer Patients
- Single Cancer Center
- ED Admissions
- More +
Chemotherapy, although beneficial for improving outcomes in both localized and metastatic cancers, may be associated with significant adverse effects, especially for patients with decreased functional reserves. Prediction of patients who will not tol... Read More
Organ-on-a-Chip and Microfluidic Platforms for Oncology in the UK
- Cancers
- VOL. 15
on Jan 19, 2023
- Organ Chips
- Physiological Mechanical Stimuli
- Biomechanical Cues
- In-house Systems
- Matrix Microenvironments
- Microphysiological Systems
- More +
Organ-on-chip systems are capable of replicating complex tissue structures and physiological phenomena. The fine control of biochemical and biomechanical cues within these microphysiological systems provides opportunities for cancer researchers to bu... Read More
MALDI Imaging Mass Spectrometry of High-Grade Gliomas: A Review of Recent Progress and Future Perspective
- Current Issues in Molecular Biology
- VOL. 45
on Jan 18, 2023
- MALDI Imaging
- Classification Of CNS Tumors
- Use Of Specific Drugs
- WHO Classification
- Short Median Survival
- Imaging Mass Spectrometry
- More +
Glioblastoma (GBM) is the most common malignancy of the brain with a relatively short median survival and high mortality. Advanced age, high socioeconomic status, exposure to ionizing radiation, and other factors have been correlated with an increase... Read More
[Progress in omics research and preclinical models of gallbladder cancer].
- Zhonghua wai ke za zhi [Chinese journal of surgery]
- VOL. 61
on Jan 18, 2023
- GBC
- Single Cell Omics
- Clinical Translation
- Omics Research
- Patient-derived Xenograft
- Microenvironment Heterogeneity
- More +
Gallbladder cancer(GBC)is one common type of bile tract cancers with poor prognosis. This review summarizes the recent development of studies about somatic mutation, molecular subtype, microenvironment heterogeneity, organoid, orthotopic model, patie... Read More
Knowledge landscape of tumor-associated macrophage research: A bibliometric and visual analysis
- Frontiers in Immunology
- VOL. 14
on Jan 18, 2023
- Bibliometric Analysis
- New Insights For Further Research
- University Of Milan
- Sun Yat-sen University
- Important Keywords
- Focus Of Attention
- More +
Background and aimsTumor-associated macrophage (TAM) is a highly abundant immune population in tumor microenvironment, which plays an important role in tumor growth and progression. The aim of our study was to explore the development trends and resea... Read More
Lifestyle, genetic risk and incidence of cancer: a prospective cohort study of 13 cancer types
- International Journal of Epidemiology
on Jan 18, 2023
- Lower Risk Of Overall Cancer
- Lifestyle Index
- PRSs
- Change In Absolute Risk
- WCRF
- Risk Of Overall Cancer
- More +
Abstract Background Genetic and lifestyle factors are associated with cancer risk. We investigated the benefits of adhering to lifestyle advice by the World Cancer Research Fund (WCRF) with the risk... Read More
Innovative informatics methods and algorithms for cancer research and management (NCI)
- Federal Grants & Contracts
- VOL. 47
on Jan 18, 2023
- Cancer Research
- Algorithms For Management
- Innovative Algorithms
- Innovative Methods
- Cancer Management
- Innovative Informatics
- More +
Sustained postconfluent culture of human mammary epithelial cells enriches\xa0for luminal and c-Kit+ subtypes
- Breast Cancer Research
- VOL. 25
on Jan 18, 2023
- Postconfluent Culture
- HMECs
- Postconfluent Cultures
- Standard Culture
- HMEC Culture
- Luminal Cells
- More +
BackgroundA challenge in human mammary epithelial cell (HMEC) culture is sustaining the representation of competing luminal, myoepithelial, and progenitor lineages over time. As cells replicate in culture, myoepithelial cells come to dominate the com... Read More
Analysis of histology-agnostic targets among soft tissue and bone sarcomas in the AACR GENIE database
- Frontiers in Oncology
- VOL. 12
on Jan 18, 2023
- STS
- Actionable Alterations
- GENIE
- Project Genomics Evidence Neoplasia Information
- AACR
- Bone Sarcoma
- More +
BackgroundThe development of novel therapies for patients with sarcoma is challenging due to the rarity and diversity of these mesenchymal neoplasms. Hence, histology-agnostic approvals can be of particular interest for the treatment of patients with... Read More
Engineering the Immune Microenvironment into Organoid Models
- Annual Review of Cancer Biology
- VOL. 7
on Jan 17, 2023
- Organoid Models
- Organoid Coculture
- Patient-derived Organoids
- Organoid Culture
- 3D Culture
- Cancer Immunotherapy
- More +
Organoid models have revolutionized cancer research through their ability to capture the cellular heterogeneity and spatial organization of a tumor in 3D culture. Patient-derived organoids can also mirror responses to therapy in vitro, opening the d... Read More
Detection of typical indigenous gut bacteria related to turmeric (Curcuma longa) powder in mouse caecum and human faecal cultures
- Molecular Biology Reports
on Jan 17, 2023
- Human Faecal Cultures
- Indigenous Gut Bacteria
- Institute Of Cancer Research Mice
- Lower Plasma Triacylglycerol Levels
- Antioxidant Properties
- Human Cultures
- More +
Turmeric (Curcuma longa; TM) is widely used as a spice and possesses anti-inflammatory, antioxidant, and antibacterial properties. The relationship between TM functions and gut microbiota is still unclear. To investigate the effect of TM on gut micro... Read More