Cambridge University Department Research Articles

Jeenay bhi do yaaron: reimagining architectural pedagogy and practice in India, 1990–2020

At the Cambridge University Department of Fine Art and Architecture, we were brought up in a tradition of architecture in which the architect was the designer of cultural artefacts. Imagination, here, was aligned to the histories and philosophies of European art and aesthetics, leading up to the ‘modern’ age. It was also concerned, primarily, with the language and expression of philosophic positions and values through form and space of buildings. At the Architectural Association, which I joined after completing my degree at Cambridge, the architect was to be a strategist exploring the systemic possibilities concerning what purposes buildings serve in a changing, dynamic world. This was aligned to systems theory and computer sciences, and the potential of new materials and technologies. And at the Tropical Studies Department, which ran a postgraduate course that evolved into the Development Planning Unit at UCL, the strategist architect or planner was to place herself as an expert of the built environment in the service of the challenging tasks of social and economic development in the developing world.

Response to Randall A & Larner AJ. Primary progressive aphasia: misdiagnosis with ‘normal’ imaging

Progress in Neurology and PsychiatryVolume 24, Issue 4 p. 31-31 LettersFree Access Response to Randall A & Larner AJ. Primary progressive aphasia: misdiagnosis with ‘normal’ imaging First published: 09 November 2020 https://doi.org/10.1002/pnp.686AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Randall and Larner1 are right to draw attention to the fact that the syndromes of primary progressive aphasia (PPA) remain unfamiliar to some clinicians. One reason is the ‘Black Magic fallacy’ – the assumption that understanding a disorder requires a highly specialised skill set. The cases presented highlight three others: the omission from standard clinical assessment of a simple test of motor speech (the ‘pataka test’); failure to appreciate the significance of subtle radiological changes such as asymmetric widening of the sylvian fissure, and the assumption that a speech/language disorder is a sign of vascular pathology. We agree that a structured clinical approach to the suspected involvement of language in a patient presenting with cognitive change could help both in overcoming barriers to the thorough assessment of patients presenting to memory clinics and in improving clinicians’ awareness of this group of disorders. In this context we were pleased to see reference to the preparation of ‘a mini linguistic state examination (MLSE)’. We have recently completed a thorough validation of this instrument in a cohort of 54 patients meeting the accepted criteria for the three main variants of PPA (authors’ Table 1).2 Although scoring of the test – which relies on the recognition of error types rather than a simple summation of correct responses – may at first seem unfamiliar, administration of the MLSE is not much more time consuming than an MMSE or MoCA, and should be able to be accommodated within a standard clinic assessment. A paper reporting the diagnostic properties of the test is currently under review, with a preprint available at www.medrxiv.org/search/MLSE. Our results suggest that the application of a few rules to classify errors across a series of simple linguistic assays (which include the ‘pataka’ test) can support rapid and confident diagnoses of semantic variant, nonfluent variant and logopenic variant PPA (svPPA, nfvPPA and lvPPA). Moreover, patients who do not fall neatly into one of these categories (‘mixed’ PPA)3 can be described, rather than omitted because the nature of their deficit is not cleanly captured by the ‘paradigm syndromes’ heuristic. The MLSE has been validated not only in English (including a cultural adaptation suitable for use in North America) but also in Italian and Spanish. Work on the more challenging modifications required to achieve equivalence in languages outside the Indo-European family is shortly to commence. The MLSE is free to use for clinical purposes, and the test can be downloaded from http://mlsexam.com on completion of a series of brief introductory tutorials. We hope that incorporation of the test in memory clinic assessments will lead to wider recognition of this group of disorders, encouraging and enabling the development of cohort-based research that will be essential to the evaluation of future therapeutic interventions. Professor Peter Garrard PhD, FRCP, Professor of Neurology, Dr Nikil Patel PhD, Research Fellow in Neuroscience, Molecular and Clinical Sciences Research Institute, St George's, University of London; Professor James Rowe PhD, FRCP, Professor of Neurology, Professor Karalyn Patterson PhD, FRS, FBA, FMedSci, Emeritus Professor, Dr Katie Petersen PhD, Research Fellow in Neuroscience, Cambridge University Department of Clinical Neuroscience, Cambridge; Professor Stefano Cappa MD, Professor of Neurology, University School for Advanced Studies (IUSS-Pavia), Italy, and Prof Matthew Lambon Ralph PhD, FBA, Director, MRC Cognition and Brain Sciences Unit, Cambridge. Declaration of interests No conflicts of interest were declared. References 1Randall A, Larner AJ. Primary progressive aphasia: Misdiagnosis with ‘normal’ imaging. Progress in Neurology and Psychiatry 2020; 24:2: 11– 13. Wiley Online LibraryWeb of Science®Google Scholar 2Vandenberghe R. Classification of the primary progressive aphasias: principles and review of progress since 2011. Alzheimers Res Ther 2016; 8: 16. PubMedWeb of Science®Google Scholar 3Grossman M. Primary progressive aphasia: clinicopathological correlations. Nat Rev Neurol 2010; 6: 88– 97. CrossrefPubMedWeb of Science®Google Scholar Volume24, Issue4October/November/December 2020Pages 31-31 ReferencesRelatedInformation

Cambridge radio sonobuoys and the seismic structure of oceanic crust

The Cambridge University Department of Geodesy and Geophysics pioneered the development of radio sonobuoys which could be used from a single ship to study the structure of the submarine crust. By contrast, contemporaneous marine seismic research, mainly in the USA, used more expensive techniques requiring the use of two ships. For nearly three decades from the early 1950s several generations of Cambridge sonobuoys were used as the primary tool to study the structure of the oceanic crust and the adjacent continental margins by seismic refraction methods, until superseded by ocean-bottom seismographs. An early result was to confirm the ubiquity across the world of relatively thin (compared with continental crust), probably volcanic, oceanic crust. This in turn underpinned the subsequent recognition of seafloor spreading and plate tectonics.

A life in science—and away from it

A life in science—and away from it

Obituary: Dr John MG Davis PhD, DSc, FRCPath

Obituary: Dr John MG Davis PhD, DSc, FRCPath

Hard frost [magnetic refrigeration technology

A small start-up company in Cambridge, called Camfridge, is assembling a refrigerator that represents a radical departure from conventional refrigeration technology. Based on the so-called magnetocalorific effect (MCE), the Camfridge design doesn't involve gases that deplete the ozone layer or cause greenhouse effect. These MCE-based refrigerators are also expected to provide a 40% reduction in electricity consumption when compared to a conventional fridge. Unfortunately, finding a magnetic refrigerant with exactly the right properties has been difficult. However, scientists at Cambridge University's Department of Metallurgy and Material Science are working on a novel room temperature giant MCE material. The material is based on a blend of cobalt, manganese, and silicon and belongs to the minority category of negative MCE magnetic refrigerants. In the meantime, the Camfridge prototype will use a gadolinium-based refrigerant as a means of testing the soundness of the design implementation.

On the Need for Multiple Lists of Chemical Information

Cambridge University Department of Chemistry has a list of University Chemistry Departments and Chemistry-related journals around the world: ChemSites (http://www.ch.cam.ac.uk/ChemSitesIndex.html). This article describes what makes it distinct from other lists, and justifies the existence of more than one such list.

Managing the Teacher Training Partnership in the Classroom

Fearnhill and The Highfield Schools have just embarked on a new partnership for initial teacher training, with Cambridge University Department of Education and Homerton College. Some guidelines on how to manage ITT through partnership are beginning to emerge from their experience and readers contemplating, or involved in, similar developments, should find these of interest. MiE welcomes further contributors on this topical issue.

Political education in Yugoslavia: practice in self‐management

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsWitold TulasiewiczWitold Tulasiewicz lectures in education at the Cambridge University Department of Education

A kind of continual conversation: a postscript to the Great Debate

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsEric HadleyEric Hadley lectures at the Cambridge University Department of Education

Consumer Demand for Cars in the U.S.A.

Journal Article Consumer Demand for Cars in the U.S.A Get access Consumer Demand for Cars in the U.S.A. By R. P. SMITH. Cambridge University Department of Applied Economics, Occasional Paper 44. (London: Cambridge University Press, 1975. Pp. ix+108. £3.80 hardback, £1.80 paperback.) John Muellbauer John Muellbauer Birkbeck College Search for other works by this author on: Oxford Academic Google Scholar The Economic Journal, Volume 86, Issue 343, 1 September 1976, Pages 649–651, https://doi.org/10.2307/2230828 Published: 01 September 1976

The role of spontaneous canine tumours in the evaluation of the aetiology and therapy of human cancer.

SUMMARYA SUMMARY OF WORK CURRENTLY IN PROGRESS IN THE CAMBRIDGE UNIVERSITY DEPARTMENT OF CLINICAL VETERINARY MEDICINE, MADINGLEY ROAD, CAMBRIDGEA brief description of the current work on animal neoplasia in progress at the Cambridge University Department of Clinical Veterinary Medicine has been presented. General Practitioners play an essential role in the programme, which cannot proceed without cases referred by them. Cases which are of special interest include osteosarcomas, lymphosarcomas and malignant melanomas for immunotherapy trials, and reticulum cell sarcomas and mastocytomas for radiotherapy and chemotherapy. The Department also runs a routine radiotherapy and histopatho‐logical service.

Brown patches in the epididymis.

Brown patches were found in the head of the epididymis in 66 out of 100 consecutive male necropsies. They appear to be lesions due to local obstruction of ductuli efferentes by dehydrated semen. These common lesions are probably similar to origin to sperm granulomas, and might be significant in the origin of sperm auto-antibodies; their further study might help to elucidate some of the outstanding problems of male fertility.

Language development in severely subnormal children

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsGillian FennGillian Fenn is Pinsent‐Darwin Student in Mental Pathology at the Cambridge University Department of Education

Curriculum Gateau: a reply

Click to increase image sizeClick to decrease image size Additional informationNotes on contributorsRichard WhitfieldRichard Whitfield is a University Lecturer in Education in the Cambridge University Department of Education

NATO Advanced Study Institute

The Cambridge University Department of Applied Mathematics and Theoretical Physics will host a NATO Advanced Study Institute on Magnetohydrodynamic Phenomena in Rotating Fluids June 26 through July 4, 1972. The aim of the meeting will be to provide, through invited lectures, a systematic account of those aspects of the geophysics of the earth–s core and of astrophysics in which both rotation effects and magnetic effects play an important part. In addition, informal presentations and discussion will be strongly encouraged.

Conference on non-conventional electron microscopy: Cambridge, March–April 1965

A report and appraisal is given of a Conference organized by the Electron Microscope and Analysis Group of the Institute of Physics and the Physical Society, held in the Cambridge University Department of Engineering, 31st March–2nd April, 1965. The main topics covered were: scanning microscopy, electron diffraction and energy analysis, low and high voltage transmission microscopy, mirror and emission microscopy, electron optics, and field-ion microscopy.

Visual aids

A new film shot by Cambridge University Department of. Education is intended to introduce teachers to the principles and techniques of programmed learning. Teaching Machines and Programmed Learning (b & w, 17 min) is a calm, factual account of how the various devices work and what they do. It assumes little or no previous knowledge of the subject and deals impartially with a range of machines and devices from the complex to the simple — including programmed texts — without overselling them or putting anyone needlessly on the defensive.

The Neolithic in The Cambridgeshire Fens

By common consent the spread of Neolithic culture has been one of the first objectives of radiocarbon dating in north-western Europe. This is due primarily to the intrinsic historical importance of this process, but the fact that the inception of husbandry has left clear indicators in the palaeobotanical record means that decisive samples are readily available. In the present paper an account will first be given of the reinvestigation of the site on Peacock’s Farm, Shippea Hill, Cambridgeshire, a locality where in 1934 Neolithic pottery had been found stratified in a vertical sequence between Mesolithic and Early Bronze Age remains, each in deposits with fossil pollen. In view of the stratigraphical importance of the site it may be appropriate in this same context to review the radiocarbon dates for the inception of Neolithic culture in the British Isles as a whole. The excavations were undertaken during June, 1960, by the Cambridge University Department of Archaeology and Anthropology with the support of the Crowther-Beynon Fund. Samples were collected for pollen analysis and radiocarbon age determination and the laboratory work was carried out in the University Sub-department of Quaternary Research at Cambridge.

THE ESTIMATION OF REGRESSION EQUATIONS WHEN THE INDEPENDENT VARIABLES ARE OTHERWISE RELATED TO THE DEPENDENT VARIABLES (*)

MetroeconomicaVolume 12, Issue 2-3 p. 39-57 THE ESTIMATION OF REGRESSION EQUATIONS WHEN THE INDEPENDENT VARIABLES ARE OTHERWISE RELATED TO THE DEPENDENT VARIABLES (*) F. E. A. Briggs, F. E. A. Briggs CambridgeSearch for more papers by this author F. E. A. Briggs, F. E. A. Briggs CambridgeSearch for more papers by this author First published: June 1960 https://doi.org/10.1111/j.1467-999X.1960.tb00271.x * The work described here was done at the Cambridge University Department of Applied Economics in 1956 and I am indebted to my colleagues there for helpful discussion of the problem ‡ I am indebted also to Dr. L. R. Klein for helpful comments on the identi-fiability of the models discussed in this paper. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Volume12, Issue2-3June 1960Pages 39-57 RelatedInformation