Built-in Assembly Research Articles

The effects of galaxy assembly bias on the inference of growth rate from redshift-space distortions

The large-scale redshift-space distortion (RSD) in galaxy clustering can probe $f\sigma_8$, a combination of the cosmic structure growth rate and the matter fluctuation amplitude, which can constrain dark energy models and test theories of gravity. While the RSD on small scales (e.g. a few to tens of $h^{-1}{\rm Mpc}$) can further tighten the $f\sigma_8$ constraints, galaxy assembly bias, if not correctly modelled, may introduce systematic uncertainties. Using a mock galaxy catalogue with built-in assembly bias, we perform a preliminary study on how assembly bias may affect the $f\sigma_8$ inference. We find good agreement on scales down to 8--9$h^{-1}{\rm Mpc}$ between a $f\sigma_8$ metric from the redshift-space two-point correlation function with the central-only mock catalogue and that with the shuffled catalogue free of assembly bias, implying that $f\sigma_8$ information can be extracted on such scales even with assembly bias. We then apply the halo occupation distribution (HOD) and three subhalo clustering and abundance matching (SCAM) models to model the redshift-space clustering with the mock. Only the SCAM model based on $V_{\rm peak}$ (used to create the mock) can reproduce the $f\sigma_8$ metric, and the other three could not. However, the $f\sigma_8$ metrics determined from central galaxies from all the models are able to match the expected one down to 8$h^{-1}{\rm Mpc}$. Our results suggest that halo models with no or incorrect assembly bias prescription could still be used to model the RSD down to scales of $\sim 8 h^{-1}{\rm Mpc}$ to tighten the $f\sigma_8$ constraint, with a sample of central galaxies or with a flexible satellite occupation prescription.

A peptide adhesive molded by magnesium glues Rubisco's subunits together

Rubisco enzymes play central roles in carbon fixation, with potential importance in biotechnology, but have eluded a full description of their multistep assembly and function. A new article describes the fascinating discovery that some archaeal Rubiscos contain a built-in assembly domain inserted into an otherwise canonical Rubisco fold, providing a tremendous expansion of our understanding of the diversity of naturally occurring Rubiscos.

Mapping Flexibility and the Assembly Switch of Cell Division Protein FtsZ by Computational and Mutational Approaches

The molecular switch for nucleotide-regulated assembly and disassembly of the main prokaryotic cell division protein FtsZ is unknown despite the numerous crystal structures that are available. We have characterized the functional motions in FtsZ with a computational consensus of essential dynamics, structural comparisons, sequence conservation, and networks of co-evolving residues. Employing this information, we have constructed 17 mutants, which alter the FtsZ functional cycle at different stages, to modify FtsZ flexibility. The mutant phenotypes ranged from benign to total inactivation and included increased GTPase, reduced assembly, and stabilized assembly. Six mutations clustering at the long cleft between the C-terminal beta-sheet and core helix H7 deviated FtsZ assembly into curved filaments with inhibited GTPase, which still polymerize cooperatively. These mutations may perturb the predicted closure of the C-terminal domain onto H7 required for switching between curved and straight association modes and for GTPase activation. By mapping the FtsZ assembly switch, this work also gives insight into FtsZ druggability because the curved mutations delineate the putative binding site of the promising antibacterial FtsZ inhibitor PC190723.

Experience with using the technology of starting modes of power units equipped with a built-in assembly

Papers on the operating modes of the starting built-in assembly used in the once-through boilers of 150-, 200-, 300-, and 500-MW power units are reviewed. It is shown that this assembly does not meet the requirements for separating steam-water medium into steam and water that are placed on it, this resulting in degraded reliability of the heating surfaces situated downstream of it. Proposals for solving these problems are given.