Educational buildings in Saudi Arabia are characterized by high energy consumption, primarily due to cooling and lighting demands. This study aims to evaluate and optimize facade retrofitting strategies to improve energy efficiency and evaluate economic performance of many scenarios in Saudi school buildings, aligning with the sustainability objectives of Saudi Vision 2030. The research employs a simulation-based optimization methodology utilizing Design Builder software to explore key facade design variables, including Window-to-Wall Ratio, glazing type, local shading devices, and external wall insulation. The methodology is structured in sequential stages: it begins with the collection of base-case data, followed by a data-driven optimization process targeting specific design variables. This is then complemented by an economic and environmental assessment of the optimal retrofit scenarios, ultimately leading to the identification of the most effective energy-saving solution presented at the conclusion of the study. Through an optimization process, the research identifies retrofitting strategies that reduce cooling loads by up to 17 %, lighting energy consumption by 49 % and annual energy costs by 18 %. The study also includes an economic analysis of the retrofits, revealing significant savings in annual electricity costs and a reduction in the building's carbon footprint. This research contributes valuable insights into sustainable building practices, offering practical solutions for improving energy efficiency in the educational sector. The novelty of this study lies in its comprehensive analysis of facade retrofits within the context of extreme climatic conditions, which provides a replicable model for retrofitting educational buildings across the region. The findings have significant implications for policymakers, architects, and sustainability advocates seeking to meet Saudi Arabia's energy conservation goals.