IV Workshop on Modeling and Simulation for Science and Engineering, Organizing Committee, National Scientific Committee and this titles are available in this pdf. This volume presents the written contributions of the participants of the IV Workshop on Modeling and Simulation for Science and Engineering (IV WMSSE) which was held from 15 to March 16, 2021, at the Bucaramanga city, Colombia, organized by the Foundation Of Researchers In Science And Technology Of Materials (FORISTOM).The Proceedings volume includes 23 manuscripts that were presented as plenary talks at the conference. The abstracts of all participants‘ contributions were published in the Book with ISSN 2745-1496. The website of the conference is available at https://foristom.org/4wmsse.The two-day scientific program of the IV WMSSE consisted of 8 magisterial remote conferences, 28 oral remote presentations, with the participation of undergraduate and graduate students, professors, researchers, and entrepreneurs from Spain, Uruguay, Brazil, Peru, Ecuador, Venezuela, and Colombia. Likewise, the main aim of IV WMSSE was to bring together national and international researchers in order to show scientific progress and to highlight the strong correlation of research in physical and mathematical modeling on science, engineering, technology, and industrial applications; besides, to promote the exchange of creative ideas and the effective transfer of scientific knowledge, from fundamental research to innovation applied to industrial solutions with of purpose to advance in the development of the society by means of efficient transference of the knowledge between sectors academia and industry.All papers in these Proceedings volume refer to one of the following topics covered in the IV WMSSE:✓ Computer Science.✓ Mechatronic Systems.✓ Dynamic Systems Modeling.✓ Physical-Chemistry Modeling.✓ Physics-Mathematical Modeling.✓ Modeling, Simulation, and Diagnostics.✓ Education on Science, Engineering, and Technology.On behalf of the organizing committee of the IV WMSSE, we are extremely thankful to all authors and participants for providing their valuable contributions for this Proceedings volume as well as the reviewers for their constructive recommendations and criticism aiding to improve the presented articles.On the other hand, it very important to note that the workshop organized by the FORISTOM foundation, is a very significant contribution to the universal scientific community, achieving the interaction of the different research groups of the sector academia and business sector of Colombia with other countries.The editor hopes that those interested in the area of Modeling and Simulation for Science and Engineering can enjoy this reading, of the volume of the Journal of Physics: Conference Series (JPCS), which reflects a wide variety of current issues. “Education and expression freedom for anyone“. Organizing Committee, National Scientific Committee, International Scientific Committee / Comité Académico Internacional, Invited Speakers / Conferencistas Invitados, Sponsor, Partners and this titles are available in this pdf.