Bubble Diagrams Research Articles

Different origins of running in the 2D CP(1) model

We revisit the computation of the beta function in the two-dimensional CP(1) sigma model. We show that in different schemes, different diagrams are responsible for the running, such as momentum-independent tadpoles or even UV-finite bubble diagrams. We also comment on the relation between the beta functions and the energy dependence of scattering amplitudes. Published by the American Physical Society 2024

Serum untargeted metabolomics analysis of mice after myocardial infarction affected by qiliqiangxin capsule

Qiliqiangxin (QLQX) capsule consists of 11 herbs, namely Huang qi (astragalus membranaceus), Ren shen (ginseng), Fu zi (radix aconiti carmichaeli), Dan shen (salvia miltiorrhiza), Ting li zi (lepidium seed), Ze xie (rhizoma alismatis), Yu zhu (radix polygonati officinalis), Gui zhi (cassia twig), Hong hua (carthamus tinctorious), Xiang jia Pi (cortex periplocae), Chen Pi (pericarpium citri reticulatae), and it is a standardized commercial formula designed to address yang deficiency and to restore the balance of qi in the heart. QLQX is also known to invigorate the blood and promote the circulation of the blood and to promote the use of fluids to relieve water retention and edema, and can be used in cardiovascular diseases such as mild to moderate congestive heart failure resulting from coronary artery disease and hypertension. The further research on the effect of QLQX on cardiac function in mice after myocardial infarction was manipulated. QLQX was given to mice in myocardial infarction model by gavage with appropriate dosage and the samples were analyzed at the end of the animal experiments through the UHPLC-Q-Exactive LC-MS. The liquid mass spectrometry was used to collect and followed by further analysis of the corresponding metabolites and metabolic pathways using metabolomics analysis. As a result, 9 differential metabolites were identified, with 15 being up-regulated and 4 down-regulated following intervention with QLQX. Then the metabolic pathways by KEGG enrichment pathway bubble diagram was analyzed, and 4 metabolic pathways were obtained, and combined with the metabolites that had been screened and analyzed together, finally the two differential metabolites, 2,5-Dihydroxybenzenesulfonic Acid and o-Cresol sulfate were found. The Glycerophospholipid metabolism pathway was closely related to the remaining seven differential metabolites, and the pathway might be an important pathway related to the effects of QLQX on cardiac function in mice.

Hidden conformal symmetry in AdS2×S2 beyond tree level

Correlators of N=2 hypermultiplets with two-derivative interactions in AdS2×S2 exhibit a hidden four-dimensional conformal symmetry which allows one to repackage all tree-level four-point correlators into a single four-dimensional object corresponding to a contact diagram arising from a massless ϕ4 theory in AdS2×S2. This theory serves as a toy model for IIB string theory in AdS5×S5 and is interesting in its own right because AdS2×S2 describes the near-horizon limit of extremal black holes in four dimensions. We argue that, after acting with an SU(1,1)×SU(2) Casimir, all one-loop correlators can similarly be encoded by a four-dimensional function which arises from a one-loop scalar bubble diagram in AdS2×S2, explaining how the hidden conformal symmetry extends beyond tree level. Finally, we conjecture a scalar effective field theory with a two-derivative interaction in AdS2×S2 whose Witten diagrams should directly reproduce four-point correlators to all loops without acting with Casimirs. Published by the American Physical Society 2024

Excellent thermoelectric properties and significant anisotropy for filled-tetragonal NaZnAs caused by strong anharmonicity

We have theoretically investigated the transport properties of the filled-tetrahedral NaZnAs using first-principles calculations in combination with self-consistent phonon theory and the Boltzmann transport equation. The results show that the transport behavior of NaZnAs exhibits obvious anisotropy, and the influence of quartic anharmonicity on the lattice thermal conductivity cannot be neglected as shown by the thermal conductivity results obtained from different computational models. Both the increase in scattering rates(SRs) and the decrease in group velocity signify a strong anharmonicity. We further find that the special vibrational modes due to the weak bonding of Zn atoms are the main source of anharmonicity. We find that considering the bubble diagram for the phonon self-energy correction reduces the κL by up to 28.04% at 700 K, which favors the capture of large ZT values. In addition, The ZT value of NaZnAs can reach 3.07 at 700 K, which shows great potential for thermoelectric applications.

Hierarchical characterization of thermoelectric performance in copper-based chalcogenide CsCu3S2: Unveiling the role of anharmonic lattice dynamics

Fundamental understanding of anharmonic lattice dynamics and heat conductance physics in crystalline compounds is critical for the development of thermoelectric energy conversion devices. Herein, we thoroughly investigate the microscopic mechanisms of thermal transport in CsCu3S2 by coupling the self-consistent phonon (SCP) theory with the linearized Wigner transport equation (LWTE). We explicitly consider both phonon energy shifts and broadening arising from both cubic and quartic anharmonicities, as well as diagonal/non-diagonal terms of heat flux operators in thermal conductivity. Our findings show that the strong anharmonicity of CsCu3S2 primarily arises from the presence of p-d anti-bonding hybridization between Cu and S atoms, coupled with the random oscillations of Cs atoms. Notably, the competition between phonon hardening described by the loop diagram and softening induced by the bubble diagram significantly influences particle-like propagation, predominantly reflected in group velocity and energy-conservation rule. Additionally, the electrical transport properties are determined by employing the precise momentum relaxation-time approximation (MRTA). At high temperatures, the thermoelectric performance of p-type CsCu3S2 reaches its optimum theoretical value of 0.94 along the in-plane direction based on advanced phonon renormalization theory. In striking contrast, the harmonic approximation theory significantly overestimates the thermoelectric efficiency at the same temperatures, rendering it an impractical expectation. Conversely, the first-order renormalization approach leads to a serious underestimation of the thermoelectric properties due to the over-correction of phonon energy. Our study not only reveals the pivotal role of anharmonic lattice dynamics in accurately assessing thermoelectric properties but also underscores the potential thermoelectric applications for novel copper-based chalcogenides.

A new framework for higher loop Witten diagrams

The differential representation is a novel formalism for studying boundary correlators in (d + 1)-dimensional anti-de Sitter space. In this letter, we generalize the differential representation beyond tree level using the notion of operator-valued integrals. We use the differential representation to compute three-point bubble and triangle Witten diagrams with external states of conformal dimension ∆ = d. We compare the former to a position space computation.

Serum untargeted metabolomics analysis of the preventive mechanism of TAETEA Prebiotea on non-alcoholic fatty liver in rats

Pu-erh tea belongs to the six tea categories of black tea, according to the processing technology and quality characteristics, is divided into two types of raw tea and ripe tea. Raw tea is made from fresh leaves of tea as raw materials, through the process of greening, kneading, sun drying, steam molding and other processes made of tightly pressed tea. Ripe tea is made from Yunnan large-leafed sun green tea, using a specific process, post-fermentation (rapid post-fermentation or slow post-fermentation) processing of loose tea and tightly pressed tea. TAETEA Prebiotea is Puerh Ripe Tea, TAETEA Prebiotea has the effect of increasing insulin level and improving hyperglycemia in mice, and it also has the effect of regulating blood lipids, which can reduce the level of serum total cholesterol (TC) and triglycerides (TG), increase the level of high-density lipoprotein cholesterol (HDL-C), and improve the metabolism of lipids. Therefore, further experiments were conducted by us, and TAETEA Prebiotea was formulated into a suitable dose for the intervention of non alcoholic fatty liver disease (NAFLD) model rats, and at the end of the experiments, the samples of each group of experiments were analyzed and detected by the method of UHPLC-Q-Exactive LC-MS liquid-mass spectrometry methodology, and the relevant metabolites as well as metabolic pathways were analyzed by the method of Non targeted metabolomics analysis. As a result, 71 differential metabolites could be screened, of which 35 differential metabolites were up-regulated after intervention and 36 differential metabolites were down-regulated after intervention. Based on the KEGG pathway enrichment and Pathway Impact bubble diagram analysis, glycine, serine, threonine metabolism, arginine and proline metabolism, protein digestion and absorption, and central carbon metabolism in cancer may be the main metabolic pathways in which TAETEA Prebiotea exerted preventive effects on NAFLD rats, C00148 (Proline), C00300 (Creatine) and C00719 (Betaine) are the differential metabolites that play important regulatory roles.

SEnSCA: Identifying possible ligand-receptor interactions and its application in cell-cell communication inference.

Multicellular organisms have dense affinity with the coordination of cellular activities, which severely depend on communication across diverse cell types. Cell-cell communication (CCC) is often mediated via ligand-receptor interactions (LRIs). Existing CCC inference methods are limited to known LRIs. To address this problem, we developed a comprehensive CCC analysis tool SEnSCA by integrating single cell RNA sequencing and proteome data. SEnSCA mainly contains potential LRI acquisition and CCC strength evaluation. For acquiring potential LRIs, it first extracts LRI features and reduces the feature dimension, subsequently constructs negative LRI samples through K-means clustering, finally acquires potential LRIs based on Stacking ensemble comprising support vector machine, 1D-convolutional neural networks and multi-head attention mechanism. During CCC strength evaluation, SEnSCA conducts LRI filtering and then infers CCC by combining the three-point estimation approach and single cell RNA sequencing data. SEnSCA computed better precision, recall, accuracy, F1 score, AUC and AUPR under most of conditions when predicting possible LRIs. To better illustrate the inferred CCC network, SEnSCA provided three visualization options: heatmap, bubble diagram and network diagram. Its application on human melanoma tissue demonstrated its reliability in CCC detection. In summary, SEnSCA offers a useful CCC inference tool and is freely available at https://github.com/plhhnu/SEnSCA.

Can GW handle multireference systems?

Due to the infinite summation of bubble diagrams, the GW approximation of Green's function perturbation theory has proven particularly effective in the weak correlation regime, where this family of Feynman diagrams is important. However, the performance of GW in multireference molecular systems, characterized by strong electron correlation, remains relatively unexplored. In the present study, we investigate the ability of GW to handle closed-shell multireference systems in their singlet ground state by examining four paradigmatic scenarios. First, we analyze a prototypical example of a chemical reaction involving strong correlation: the potential energy curve of BeH2 during the insertion of a beryllium atom into a hydrogen molecule. Second, we compute the electron detachment and attachment energies of a set of molecules that exhibit a variable degree of multireference character at their respective equilibrium geometries: LiF, BeO, BN, C2, B2, and O3. Third, we consider a H6 cluster with a triangular arrangement, which features a notable degree of spin frustration. Finally, the dissociation curve of the HF molecule is studied as an example of single bond breaking. These investigations highlight a nuanced perspective on the performance of GW for strong correlation depending on the level of self-consistency, the choice of initial guess, and the presence of spin-symmetry breaking at the Hartree-Fock level.

Demand analysis of general practice patients for teaching clinic based on Kano model.

General practice teaching clinics play a crucial role in the training of general practitioners, as they are more likely to enhance reception skills compared to traditional training methods. The quality of teaching clinics is largely determined by the level of patient acceptance. In recent years, the Kano model has become increasingly popular in the healthcare industry and has been used to enhance patient satisfaction. The objective of this study is to apply the Kano model to investigate the needs of patients in general practice teaching clinics and to rank the significance of each demand. This study will serve as a reference for enhancing the service quality of teaching clinics and advancing the field of general practice. A total of 101 patients of general practice at the Affiliated Hospital of Yangzhou University in Jiangsu province were selected using a random convenience sampling method to participate in a questionnaire survey. The questionnaire was designed by members of our team and was based on the Kano model. The study defined the service demand, assessed the impact of both satisfaction and dissatisfaction and created a matrix bubble diagram. The study findings revealed that out of the 14 items of the general practice teaching clinic service demands, 1 item was categorized as a must-be requirement, 4 items were categorized as one-dimensional requirements, 2 items were categorized as an attractive requirement, 2 items were categorized as an indifferent requirement, and 5 items were categorized as mixed attributes. The findings of the matrix analysis showed that 4 items were situated in the area of one-dimensional attributes quadrant, 3 items were situated in the area of attractive attributes quadrant, 5 items were situated in the area of indifferent attributes quadrant, and 2 items were situated in the area of must-be attributes quadrant. The patients of general practice have positive attitudes toward teaching clinics. The findings can offer valuable insights for enhancing the quality of service and patient experience in general practice teaching clinics as well as for advancing the field of general practice.

RG flows and fixed points of O(N)r models

By means of ϵ and large N expansions, we study generalizations of the O(N) model where the fundamental fields are tensors of rank r rather than vectors, and where the global symmetry (up to additional discrete symmetries and quotients) is O(N)r, focusing on the cases r ≤ 5. Owing to the distinct ways of performing index contractions, these theories contain multiple quartic operators, which mix under the RG flow. At all large N fixed points, melonic operators are absent and the leading Feynman diagrams are bubble diagrams, so that all perturbative fixed points can be readily matched to full large N solutions obtained from Hubbard-Stratonovich transformations. The family of fixed points we uncover extend to arbitrary higher values of r, and as their number grows superexponentially with r, these theories offer a vast generalization of the critical O(N) model.We also study sextic O(N)r theories, whose large N limits are obscured by the fact that the dominant Feynman diagrams are not restricted to melonic or bubble diagrams. For these theories the large N dynamics differ qualitatively across different values of r, and we demonstrate that the RG flows possess a numerous and diverse set of perturbative fixed points beginning at rank four.

Unravelling ultralow thermal conductivity in perovskite Cs2AgBiBr6: dominant wave-like phonon tunnelling and strong anharmonicity

Understanding the lattice dynamics and heat transport physics in the lead-free halide double perovskites remains an outstanding challenge due to their lattice dynamical instability and strong anharmonicity. In this work, we investigate the microscopic mechanisms of anharmonic lattice dynamics and thermal transport in lead-free halide double perovskite Cs2AgBiBr6 from first principles. We combine self-consistent phonon calculations with bubble diagram correction and a unified theory of lattice thermal transport that considers both the particle-like phonon propagation and wave-like tunnelling of phonons. An ultra-low thermal conductivity at room temperature (~0.21 Wm−1K−1) is predicted with weak temperature dependence( ~ T−0.34), in sharp contrast to the conventional ~T−1 dependence. Particularly, the vibrational properties of Cs2AgBiBr6 are featured by strong anharmonicity and wave-like tunnelling of phonons. Anharmonic phonon renormalization from both the cubic and quartic anharmonicities are found essential in precisely predicting the phase transition temperature in Cs2AgBiBr6 while the negative phonon energy shifts induced by cubic anharmonicity has a significant influence on particle-like phonon propagation. Further, the contribution of the wave-like tunnelling to the total thermal conductivity surpasses that of the particle-like propagation above around 310 K, indicating the breakdown of the phonon gas picture conventionally used in the Peierls-Boltzmann Transport Equation. Importantly, further including four-phonon scatterings is required in achieving the dominance of wave-like tunnelling, as compared to the dominant particle-like propagation channel when considering only three-phonon scatterings. Our work highlights the importance of lattice anharmonicity and wave-like tunnelling of phonons in the thermal transport in lead-free halide double perovskites.

Current state of research on acupuncture for the treatment of post-stroke dysphagia: a scoping review.

Post-stroke dysphagia (PSD) is a common complication of stroke. Acupuncture as one of the traditional therapies in traditional Chinese medicine (TCM), can change the excitability of cerebral cortical nerve cells, and promote the recovery of neurological and swallowing functions. Several clinical primary studies (including RCTs, cohort studies, etc.) and systematic reviews have demonstrated its efficacy and safety in patients with PSD. The positive effects of acupuncture on PSD are also mentioned in international clinical and treatment guidelines, while there is no synthesis of this evidence. This scoping review aims to summarize the evidence from clinical primary studies, reviews, systematic reviews, and guidelines on acupuncture for the treatment of PSD and explore the breadth of this evidence, provide an overview of the range and characteristics of existing evidence, research gaps, and future research priorities in treating PSD with acupuncture. PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, SinoMed, Wan Fang Data, and VIP databases were searched from inception until June 12, 2024. The relevant data were presented through bubble diagrams, line graphs, and structured tables along with descriptive statistics and analysis. This scoping review was conducted based on the PRISMA-ScR Checklist. A total of 1,130 studies were included. Most of the studies were conducted in China, with the number increasing over time. The studies included 254 reviews, 815 clinical studies (678 RCTs,107 nRCTs, 12 case reports, 14 cohort studies, and four case series), 51 systematic reviews, and 10 guidelines. Acupuncture interventions included manual acupuncture (MA), electroacupuncture (EA), and MA/EA combined with acupuncture-related methods (such as scalp acupuncture, auricular acupuncture, warm acupuncture, etc.). The most frequently used acupoint was RN23. Acupuncture is often applied in combination with other treatments, such as herbal medicine, Western medicine, rehabilitation training, swallowing training, or catheter balloon dilatation. Effective rates and WTS were the most frequently used outcomes. Most studies reported significant efficacy and only a few studies explicitly reported adverse events. Acupuncture received positive recommendations in nine guidelines for the treatment of PSD. As a convenient and safe traditional Chinese medicine therapy with its characteristics, acupuncture can improve different stages and types of dysphagia without causing serious adverse reactions. In the future, more standardized international cooperative clinical research is needed to identify the influence of different acupuncture intervention times on the curative effect and dose-effect relationship of acupuncture; standardize the clinical acupoint selection scheme of acupuncture; develop a COS with TCM characteristics to improve the quality of outcome reporting, This will enable different research data to be summarized and compared, reduce resource waste, and provide more high-quality evidence.

Regional development potential of underground pumped storage power station using abandoned coal mines: A case study of the Yellow River Basin, China

China is gradually transforming its coal-based energy supply structure towards sustainable development, resulting in a growing number of abandoned coal mines. Underground pumped storage power stations (UPSPS) using abandoned coal mines efficiently utilize the coal mine space and promote renewable energy applications. This paper introduces a novel framework to evaluate the UPSPS regional development potential in the Yellow River Basin (YRB) from the perspective of sustainable development. A fuzzy normal cloud model based on the combined weight (FNCM-CW) is proposed to calculate the advantages and the four-quadrant method incorporating bubble diagrams is employed to merge the advantage grades. The results indicate that the construction investment, reservoir volume, transport conditions and policy support are the most important indexes affecting the regional development of UPSPS. Shanxi and Inner Mongolia have accumulated a large number of abandoned coal mine resources with shallow mining depths and high productivity. The distribution of economic, technological, environmental and social advantages in the YRB is uneven, where the upstream areas have abundant wind and solar energy resources, the midstream possesses urgent energy transformation demand and the downstream features a stronger economic foundation. The ranking result of the UPSPS regional development potential is: Shanxi > Inner Mongolia > Shandong > Henan > Ningxia > Sichuan > Shaanxi > Qinghai > Gansu. This paper provides decision support for UPSPS engineering practice and is a reference for other countries and coal-producing areas.

Study on bubble dynamics in sodium using three-dimensional MPS method

Sodium-cooled fast reactor (SFR) is one of the most promising Generation IV reactors. Design and safety evaluation of a SFR requires sufficient knowledge about gas bubble behavior in sodium pool. It is challenging to perform numerical study on bubble dynamics in sodium pool due to the discontinuity caused by the differences of physical properties. In this study, a three-dimensional (3D) Moving Particle Semi-implicit (MPS) method is presented featuring high-order accurate scheme and Riemann-based stable multiphase model. Numerical discontinuity caused by large density, large viscosity ratio and surface tension can be handled by the proposed method. To verify the proposed method, two cases from the bubble diagram of Grace (1973) is simulated and rising velocities and shapes of rising gas bubbles are compared, both are agreeing very well. Then co-axial coalescence of gas bubbles are calculated and compared with existing experimental and numerical results. Finally bubble rising behavior in sodium is analyzed using the developed 3D MPS method.

Scalar QED in AdS

We consider scalar QED with Nf flavors in AdSD. For D < 4 the theory is strongly-coupled in the IR. We use the spin 1 spectral representation to compute and efficiently resum the bubble diagram in AdS, in order to obtain the exact propagator of the photon at large Nf. We then apply this result to compute the boundary four-point function of the charged operators at leading order in 1/Nf and exactly in the coupling, both in the Coulomb and in the Higgs phase. In the first case a conserved current is exchanged in the four-point function, while in the second case the current is absent and there is a pattern of double-trace scaling dimension analogous to a resonance in flat space. We also consider the BCFT data associated to the critical point with bulk conformal symmetry separating the two phases. Both in ordinary perturbation theory and at large Nf, in integer dimension D = 3 an IR divergence breaks the conformal symmetry on the boundary by inducing a boundary RG flow in a current-current operator.

BubbleFormer: Bubble Diagram Generation via Dual Transformer Models

AbstractBubble diagrams serve as a crucial tool in the field of architectural planning and graphic design. With the surge of Artificial Intelligence Generated Content (AIGC), there has been a continuous emergence of research and development efforts focused on utilizing bubble diagrams for layout design and generation. However, there is a lack of research efforts focused on bubble diagram generation. In this paper, we propose a novel generative model, BubbleFormer, for generating diverse and plausible bubble diagrams. BubbleFormer consists of two improved Transformer networks: NodeFormer and EdgeFormer. These networks generate nodes and edges of the bubble diagram, respectively. To enhance the generation diversity, a VAE module is incorporated into BubbleFormer, allowing for the sampling and generation of numerous high‐quality bubble diagrams. BubbleFormer is trained end‐to‐end and evaluated through qualitative and quantitative experiments. The results demonstrate that BubbleFormer can generate convincing and diverse bubble diagrams, which in turn drive downstream tasks to produce high‐quality layout plans. The model also shows generalization capabilities in other layout generation tasks and outperforms state‐of‐the‐art techniques in terms of quality and diversity. In previous work, bubble diagrams as input are provided by users, and as a result, our bubble diagram generative model fills a significant gap in automated layout generation driven by bubble diagrams, thereby enabling an end‐to‐end layout design and generation. Code for this paper is at https://github.com/cgjiahui/BubbleFormer.

Expert judgement of collaborative cloud classroom quality and its criteria using the many-facets rasch model

Collaborative Cloud Classroom (3CR) is an educational application that provides flexibility in the learning process. This specialized tool is designed to improve analytical and teambuilding skills, as well as enable students to document ideas, which are subsequently developed into bubble diagrams and text outlines. This study aims to assess and analyze the menu qualities possessed by the 3CR application using the Many-Facet Rasch Model (MFRM) analysis using 5 raters and 6 menus. A rating assessment was applied to 5 criteria, namely usability, functionality, visual communication, learning design, and security. In this case, a total of 135 from 150 data points were coded into FACETS software. The results showed that the six menus in the 3CR application were valid and reliable, as well as met the quality standards of learning tools. Security criteria were also the most difficult standards for raters to measure in all the application menus. The study also found that Rater A was more severe, and Rater E was more lenient in rating the 3CR menu. Rater B has overfitting and detected bias between rater gender and 3CR's menu (Discussion Forum and Learning Reflection menu) based on MFRM analysis.

Integrating by parts at finite density

Both nonzero temperature and chemical potentials break the Lorentz symmetry present in vacuum quantum field theory by singling out the rest frame of the heat bath. This leads to complications in the application of thermal perturbation theory, including the appearance of novel infrared divergences in loop integrals and an apparent absence of four-dimensional integration-by-parts (IBP) identities, vital for high-order computations. Here, we propose a new strategy that enables the use of IBP techniques in the evaluation of Feynman integrals, in particular vacuum or bubble diagrams, in the limit of vanishing temperature T but nonzero chemical potentials μ. The central elements of the new setup include a contour representation for the temporal momentum integral, the use of a small but nonzero T as an IR regulator, and the systematic application of both temporal and spatial differential operators in the generation of linear relations among the loop integrals of interest. The relations we derive contain novel inhomogeneous terms featuring differentiated Fermi-Dirac distribution functions, which severely complicate calculations at nonzero temperature, but are shown to reduce to solvable lower-dimensional objects as T tends to zero. Pedagogical example computations are kept at the one- and two-loop levels, but the application of the new method to higher-order calculations is discussed in some detail.

Thermal neutrino self-energy beyond the contact approximation

Using the Schwinger proper time method I calculate exactly the bubble diagram contribution to the thermal neutrino self-energy, obtaining exact results that cannot be achieved using the contact approximation. These results allow me to obtain the dispersion relation for neutrino in a medium under several different conditions.