Introduction: Paranasal sinuses can be defined as air-filled cavities lined with mucosa. Although there is a limited number of previous studies that have addressed the relationship between anatomical variations in these sinuses and dentistry, it is essential to emphasize the significance of morphofunctional knowledge of the maxillary sinus (MS) and frontal sinus (FS) for various dental specialties. Objectives: To investigate and analyze anatomical variations in selected paranasal sinuses (MS and FS) from the embryonic period to advanced age, and to correlate them with their diverse applications in dental practice. Methods: Electronic databases PubMed, Lilacs (via Bvsalud), and Scielo were consulted using the descriptors: "anatomical variation," "maxillary sinus," "frontal sinus," "dentistry," and their English counterparts. Initially, a total of 334 published articles were found, and after reading the abstracts and applying inclusion and exclusion criteria, 19 articles were analyzed. Results: The main morphological variations found included changes in dimension, number, characteristics of septations, and physiological pneumatization, which vary with age, sex, and facial sides. Among the dental implications, notable aspects include associated pathologies, techniques for maxillary sinus elevation in implantology, craniofacial profile relationships, connections with orthodontics and forensic dentistry, imaging techniques, and general surgical treatments. Conclusion: The literature reviewed suggests that the morphology of the sinuses analyzed directly influences dental practice, contributing to the improvement of clinical, forensic, surgical, and other procedures. However, studies involving the subject matter are still scarce, thus requiring further investigations.