Bridged Structure Research Articles

Microreactor with coupled oscillatory flow: Research on liquid–solid two-phase characteristics and clogging mechanism

Dealing with multiphase systems containing solid particles in microreactor is a great challenge. Herein, microreactor with coupled oscillation technology was designed to explore clogging mechanism. The simulation revealed that no vortex was generated in the straight-tube microreactor. In the helical microreactor, the vortex could be generated and destroyed periodically. Second, the deposition clogging mechanism was explored. Solid particles were deposited and agglomerated without oscillation. After coupled oscillation, agglomerations were reduced, but deposition still existed in the straight microreactor. In the helical microreactor, the deposition phenomenon could be eliminated. Finally, the bridging clogging mechanism was explored. Solid particles were deposited first and then bridged without oscillation, forming a local high viscosity zone, and eventually completely clogging the reactor. After coupled oscillation, it was difficult to destroy the bridging behavior in the straight microreactor. In the helical microreactor, the periodic vortex could effectively destroy the bridging structure and the particles flowed uniformly.

Copper(II) complexes of hindered diazines: methylquinoxalines

Five new copper(II) complexes of substituted quinoxaline ligands have been prepared and characterized via single crystal X-ray diffraction, including [Cu(5-Mequinox)2(NO3)2] (2), [Cu(5-Mequinox)(NO3)(H2O)(μ-1,3-NO3)]n (3), the chloride salt (5-MequinoxH)2[Cu3Cl8] (4), the complex [Cu(6-Mequinox)2(NO3)2] (5) and [(2-carboxylato-3-methylquinox)(2-hydroxymethyl-3-methylquinox)nitratocopper(II)]. CH3CN (6) [quinox = quinoxaline; 5-Mequinox = 5-methylquinoxaline; 6-Mequinox = 6-methylquinoxaline]. None of the complexes produced diazine bridged chain structures (as seen in [(quinox)Cu(NO3)2]n (1)), although 3 forms chains via a bridging nitrate ion. Crystal packing is controlled primarily through hydrogen bonding and π-stacking of nitrate ions. The temperature dependent magnetic susceptibility data of the parent compound [(quinox)Cu(NO3)2]n are also reported and discussed.

Visualization experiment on dynamic migration and sealing mechanism of irregular materials in rough fractures

Lost circulation is one of the main problems causing low drilling efficiency and high drilling costs in the oil and gas industry. Due to an insufficient understanding of the migration and sealing mechanism of lost circulation materials (LCMs) in rough fractures, the success of fracture sealing is highly unpredictable. This study conducted visualization experiments using four types of LCMs to observe the entire dynamic sealing process of rough fractures. Adaptive fracture sealing experiments were designed to improve the sealing performance of LCMs at low concentrations. The results indicated that the key to sealing rough fractures is forming an effective sealing zone inside the fracture space rather than in the inlet buffer zone. The dynamic sealing process has experienced four typical stages: sporadic bridging, bridging structure expansion, sealing front formation, and sealing layer thickening. The first three typical stages correspond to flow from plate flow to trench flow and seepage. The formation of an effective sealing zone within fractures depends on forming a practical sealing front and subsequent particle accumulation of LCMs that thicken the sealing layer. Compared with regular particles, the sealing front of irregular particles is an area with a specific aperture range. The increase in irregular particle concentration makes the sealing front migrate to the fracture entrance, which is more likely to lead to inlet blockage. The distribution of a sealing zone depends upon the surface morphology of rough fracture. Increasing the particle size distribution improves the favorable bridging area and enhances the sealing performance. The adaptive sealing strategy uses low-concentration granular materials to form multi-point bridging within rough fractures and low-concentration flaky materials to adaptively and quickly extend and connect dispersed bridging structures. Mica flakes are more conducive to extending along the contour of fracture aperture than calcium carbonate particles. Adding mica flakes promotes the expansion of the bridging structures, forming a sealing front and a robust sealing layer in advance. This study delves into irregular materials' migration and sealing mechanisms in rough fractures, enriching theoretical understanding and providing guidance for on-site sealing operations.

Dynamic Gas-Bridged Bond: An Opportunity of Fabricating Dynamic Assembled Materials with Gas.

Gas molecules, as a family of unique polyatomic building blocks, have long been considered hard to involve in molecular assembly or construct assembled materials due to their structural simplicity yet paucity of defined interacting sites. To solve this non-trivial challenge, a core idea is to break the limit of current ways of bonding gas molecules, endowing them with new modes of interactions that match the basic requirements of molecular assembly. In recent years, a new concept, named the dynamic gas-bridged bond (DGB), has emerged, which allows for gas molecules to constitute a dynamic bridging structure between other building blocks with the aid of frustrated Lewis pairs. This makes it possible to harness gas in a supramolecular or dynamic manner. Herein, this perspective discusses distinct dynamic natures of DGBs and manifests their particular functions in various fields, including the control of molecular/polymeric self-assembly nanostructures, creation of multidimensional assembled materials, and recyclable catalysts. The future research direction and challenges of dynamic gas-bridged chemistry toward gas-programmed self-assembly and gas-constructed adaptive materials are highlighted.

The Influence of Disulfide, Thioacetal and Lanthionine-Bridges on the Conformation of a Macrocyclic Peptide.

Cyclisation of peptides by forming thioether (lanthionine), disulfide (cystine) or methylene thioacetal bridges between side chains is established as an important tool to stabilise a given structure, enhance metabolic stability and optimise both potency and selectivity. However, a systematic comparative study of the effects of differing bridging modalities on peptide conformation has not previously been carried out. In this paper, we have used the NMR deconvolution algorithm, NAMFIS, to determine the conformational ensembles, in aqueous solution, of three cyclic analogues of angiotensin(1-7), incorporating either disulfide, or non-reducible thioether or methylene thioacetal bridges. We demonstrate that the major solution conformations are conserved between the different bridged peptides, but the distribution of conformations differs appreciably. This suggests that subtle differences in ring size and bridging structure can be exploited to fine-tune the conformational properties of cyclic peptides, which may modulate their bioactivities.

Unveiling the anion-specific effect induced structure and behavior variations on a single chitin chain

Ion-specific effects have a profound impact on the macroscopic properties of polysaccharides such as the aggregation and solubility in solutions. However, the underlying molecular mechanisms still require exploration. In this study, we investigated the influence of anions on the structure and behavior of chitin via a combination of single-molecule techniques and macroscopic characterizations. Our findings reveal that the hydration of anions functions as bridging center, leading to the formation of water-ion-water bridges between chitin side groups. Remarkably, this structure exhibits a binding affinity to chitin following the Hofmeister series with the order of F− < Cl− < Br− < I−, resulting in an escalating of left-handed helix order of chitin. Subsequent experiments indicate that the bridging structure affects the size of chitin aggregates in the similar manner, implying the impact of anions on the structure and behavior of chitin across length scales. These results provide valuable insights into the understanding of ion-specific effects on polysaccharides and its applications in food science where high salt environments are involved.

High-Performance Supercapacitor Electrodes from Fully Biomass-Based Polybenzoxazine Aerogels with Porous Carbon Structure.

In recent years, polybenzoxazine aerogels have emerged as promising materials for various applications. However, their full potential has been hindered by the prevalent use of hazardous solvents during the preparation process, which poses significant environmental and safety concerns. In light of this, there is a pressing need to explore alternative methods that can mitigate these issues and propel the practical utilization of polybenzoxazine aerogels. To address this challenge, a novel approach involving the synthesis of heteroatom self-doped mesoporous carbon from polybenzoxazine has been devised. This process utilizes eugenol, stearyl amine, and formaldehyde to create the polybenzoxazine precursor, which is subsequently treated with ethanol as a safer solvent. Notably, the incorporation of boric acid in this method serves a dual purpose: it not only facilitates microstructural regulation but also reinforces the backbone strength of the material through the formation of intermolecular bridged structures between polybenzoxazine chains. Moreover, this approach allows ambient pressure drying, further enhancing its practicability and environmental friendliness. The resultant carbon materials, designated as ESC-N and ESC-G, exhibit distinct characteristics. ESC-N, derived from calcination, possesses a surface area of 289 m2 g-1, while ESC-G, derived from the aerogel, boasts a significantly higher surface area of 673 m2 g-1. Furthermore, ESC-G features a pore size distribution ranging from 5 to 25 nm, rendering it well suited for electrochemical applications such as supercapacitors. In terms of electrochemical performance, ESC-G demonstrates exceptional potential. With a specific capacitance of 151 F g-1 at a current density of 0.5 A g-1, it exhibits superior energy storage capabilities compared with ESC-N. Additionally, ESC-G displayed a more pronounced rectangular shape in its cyclic voltammogram at a low voltage scanning rate of 20 mV s-1, indicative of enhanced electrochemical reversibility. The impedance spectra of both carbon types corroborated these findings, further validating the superior performance of ESC-G. Furthermore, ESC-G exhibits excellent cycling stability, retaining its electrochemical properties even after 5000 continuous charge-discharge cycles. This robustness underscores its suitability for long-term applications in supercapacitors, reaffirming the viability of heteroatom-doped polybenzoxazine aerogels as a sustainable alternative to traditional carbon materials.

Synthesis of Azabicyclo[3.1.1]heptenes Enabled by Catalyst-Controlled Annulations of Bicyclo[1.1.0]butanes with Vinyl Azides.

Bridged bicyclic scaffolds are emerging bioisosteres of planar aromatic rings under the concept of "escape from flatland". However, adopting this concept into the exploration of bioisosteres of pyridines remains elusive due to the challenge of incorporating a N atom into such bridged bicyclic structures. Herein, we report practical routes for the divergent synthesis of 2- and 3-azabicyclo[3.1.1]heptenes (aza-BCHepes) as potential bioisosteres of pyridines from the readily accessible vinyl azides and bicyclo[1.1.0]butanes (BCBs) via two distinct catalytic annulations. The reactivity of vinyl azides tailored with BCBs is the key to achieving divergent transformations. TiIII-catalyzed single-electron reductive generation of C-radicals from BCBs allows a concise (3 + 3) annulation with vinyl azides, affording novel 2-aza-BCHepe scaffolds. In contrast, scandium catalysis enables an efficient dipolar (3 + 2) annulation with vinyl azides to generate 2-azidobicyclo[2.1.1]hexanes, which subsequently undergo a chemoselective rearrangement to construct 3-aza-BCHepes. Both approaches efficiently deliver unique azabicyclo[3.1.1]heptene scaffolds with a high functional group tolerance. The synthetic utility has been further demonstrated by scale-up reactions and diverse postcatalytic transformations, providing valuable azabicyclics including 2- and 3-azabicyclo[3.1.1]heptanes and rigid bicyclic amino esters. In addition, the related sp2-hybridized nitrogen atom and the similar geometric property between pyridines and corresponding aza-BCHepes indicate that they are promising bioisosteres of pyridines.

Transport behavior of particles and evolution of plugging zones in rough fractures: Insights from a novel coupled CFD-DEM model

The meso-mechanism of particle bridging and plugging in rough fractures remains unclear. Therefore, this study explores a novel meso-model for simulating particle transport in rough fractures by combining Computational Fluid Dynamics and Discrete Element Method (CFD-DEM). The dynamic behavior of particles and the corresponding evolution mechanism of plugging zones are investigated. The simulation innovatively uses particle boundaries to correct fluid flow, greatly simplifying the fluid mesh partitioning while ensuring accuracy. The results reveal the connection between particles’ transport and bridging behavior in rough fracture spaces, the distribution characteristics of plugging zones, and fluid flow characteristics. The distribution of bridging favorable zones determines the position and pattern of the front edge of subsequent plugging zones. The stress accumulated by particles has little effect on the strong force chain of the front edge. The force chain strength of the double-particle bridging structure is greater than that of the single-particle bridging structure. Due to weak shear planes, the double-particle bridging structure is more prone to shear failure and instability under external loads. Improving the particle size distribution range can reduce bridging blind zones and achieve better sealing performance. The results provide theoretical help for the design of field operation processes.

A Thioether‐Bridging Surface Modification of Polymeric Microspheres Offers Nonbiological Protein A‐Mimetic Affinity for IgG

AbstractSurface modification of polymeric materials to control their interaction with proteins has been studied extensively, leading to widespread bio‐applications. However, the development of nonbiological, smart polymer surfaces, mimicking the recognition ability of biomolecules, remains a challenge. The present study presents a thioether‐bridging surface modification of polymeric microspheres as a new approach for mimicking protein A affinity for immunoglobulin G (IgG). The bridge‐modified surface is created through an epoxide linking reaction of porous polymeric microspheres with potassium thioacetate in a 2:1 molar ratio, acting as a protein A ligand, which is essential for industrial IgG purification. This surface exhibits buffer responsiveness and selective high‐affinity binding to the IgG Fc region. Remarkably, a comparison among the binding behaviors of a series of thioether‐modified microspheres indicates that bridging structures composed of β,β′‐dihydroxysulfide play a predominant role in IgG recognition. This straightforward approach can lead to the development of economical and practical nonbiological alternatives to protein A‐conjugated materials, providing solutions for various applications such as biosensors and site‐specific reagents utilizing the affinity of the IgG Fc region. The improved understanding of protein interactions at bridged/non‐bridged interfaces can be valuable in various applications such as implant materials and biomaterials.

Hidrocystoma-like tumours with RET or ALK fusion: a study of four cases

Hidrocystoma is thought to be a benign retention cyst of sweat ductal units. The lesion is usually located in the periorbital skin; however, lesions with similar histopathological features are rarely observed in extra-facial sites. Herein, we present four cases of hidrocystoma-like tumours in extra-facial skin sites that harboured a RET or ALK rearrangement. This study features a 67-year-old female with a 10 mm-sized digital tumour (Case 1), a 62-year-old male with an 8 mm-sized clavicular tumour (Case 2), a 61-year-old male with a 19 mm-sized digital tumour (Case 3), and an 11-year-old female with a 10 mm-size lower leg tumour (Case 4) as well as five control cases (Cases 5-9) of classical periorbital hidrocystoma. In Cases 1-4, multicystic tumours comprising a two-cell layer of inner cuboidal ductoglandular (p63- and SOX10+/-) and outer flat myoepithelial (p63+ and SOX10+) cells were observed. The inner ductoglandular tumour cells exhibited micropapillary projections and Roman bridging structures. No apparent atypical cells were observed. NCOA4::RET in Cases 1 and 3, CCDC6::RET in Case 2, and SLC12A2::ALK in Case 4 were revealed by next-generation sequencing or Sanger sequencing. In contrast, control cases of classical hidrocystoma (Cases 5-9) did not show intracystic proliferation, abundant cytoplasm, ALK immunoreactivity, or NCOA4::RET detection in the tumour cells. RET/ALK-rearranged hidrocystoma-like tumours are tumour entities that can be distinguished from classical hidrocystoma. This RET/ALK-rearranged neoplasm is benign and is frequently observed in the digits. Future studies will establish the concept, detailed clinicopathological characteristics, and genetic variations of hidrocystoma-like tumours.

In Situ Study on the Structural Evolution of Flexible Ionic Gel Sensors

With the development of society, the demand for smart coatings is increasing. The development of flexible strain sensors using block copolymer self-assembled ionic gel materials provides a promising method for promoting the development of smart coatings. The ionic liquid in the ionic part of the material is crucial for the performance of the sensor. In this study, the structural changes within FDA/dEAN (self-assembly of acrylated Pluronic F127 (F127-DA) in partially deuterated ethylammonium nitrate (dEAN)) triblock copolymer ionic gel during uniaxial tensile flow were characterized using an in situ SAXS technique. The results revealed that the characteristics of the responses of the ionic gel to strain resistance were intricately linked to the evolution of its microstructure during the tensile process. At low levels of strain, the face-centered cubic lattice arrangement of the micelles tended to remain unchanged. However, when subjected to higher strains, the molecular chains aligned along the stretching direction, resulting in a more ordered structure with reduced entropy. This alignment led to significant disruption in bridging structures within the material. Furthermore, this research explored the impact of the stretching rate on the relaxation process. It was observed that higher stretching rates led to decreases in the average relaxation time, indicating rate dependence in the microstructure’s behavior. These findings provide valuable insights into the behavior and performance of flexible strain sensors based on ionic gel materials in smart coatings.

MoS2/graphdiyne nanotube/MXene 3D-interconnected ternary aerogel: A high-performance electrocatalyst for hydrogen evolution reaction

MoS2 is a promising challenger to Pt for the HER, but we must make it more durable before it can take over the hydrogen production scene. This work fabricated and evaluated a hybrid structure of MXene-graphydine nanotube-MoS2 (MGMX) aerogel toward HER. It showed efficient and stable activity H2 evolution with ƞ10 = 109 mV vs RHE and a Tafel slope of 55 mVdec−1. The catalytic performance results from a synergistic interplay between increased exposed active sites and improved charge transfer within the catalyst. The two-dimensional (2D) islands of double-phase MoS2 are directly deposited onto graphdiyne nanotubes (GDNTs) surface, creating a structurally interesting material with interconnected components. The unique combination of sp and sp2 carbon atoms in the graphdiyne (GDY) makes it an ideal support for catalyst material. The combination of high edge density in metallic MoS2, a conducting MXene framework, and the bridging structure of GDNT significantly enhance the overall HER performance of the ternary aerogel structure.

Synergistic improvement in gas separation performance of MMMs by porogenic action and strong molecular forces of ZIF-93

In the present study, ZIF-93 metal–organic frameworks were prepared. N2 adsorption tests revealed that the particle size, specific surface area, and pore size of ZIF-93 were 30 nm–45 nm, 869.40 m2/g, and 0.36 nm, respectively. Pebax-based mixed matrix membranes (MMMs) were prepared using ZIF-93 as the filler. The pore diameters of ZIF-93 lied between the kinetic diameters of CO2 and N2; thus, its pore structure provided a fast transfer channel for CO2 and increased the permeability of the membrane. Further, X-ray diffraction showed that the membrane became denser upon introducing ZIF-93 because of the formation of a bridging structure between the Pebax molecular chains and ZIF-93. A denser stacking by moving the Pebax molecular chains closer to each other effectively bettered the CO2 selectivity of the mixed matrix membrane. The test results showed that when the ZIF-93 loading was 10 wt%, the CO2 permeability was 84.85 barrer and the CO2/N2 selectivity was 65.76 at 0.4 MPa, which are 51.57 % and 65.50 % higher than those of the pure Pebax membrane, respectively. When the feed pressure was increased to 0.8 MPa, the CO2 permeability was 94.5 barrer and the CO2/N2 selectivity is 87.5, which are 51.57 % and 65.50 % higher compared with those of the pure Pebax membrane, in order. The membrane performance significantly exceeded that of the 2008 Robeson curve.

Direct ink writing of viscous inks in variable gravity regimes using parabolic flights

Additive manufacturing (AM) has significant utility for off-planet fabrication where dedicated infrastructure is severely limited, weight reduction and in situ resource utilization is desirable, and demands for complex systems are high. Direct ink writing (DIW) is a useful AM technique since it enables the deposition of a broad set of materials and the co-printing of multiple materials simultaneously. This allows for the fabrication of complex functional devices and systems in addition to structural objects. To evaluate this technique for space applications, this study characterized DIW in low gravity environments. Parabolic flights were used to simulate Martian, Lunar, and Micro gravity, and the effects that these 3 gravity regimes have on two critical print performance parameters, drooping and slumping, was evaluated using viscous paste inks deposited with an auger-driven extrusion head. In the drooping case, bridging structures were printed across gaps without support material, and the deformation was monitored. In the slumping case, a wall was printed through sequential layer deposition, and the vertical displacement of each layer under reduced gravity was explored. As expected, we found that a reduction in apparent gravity led to a decrease in the droop of a printed line, and as apparent gravitational acceleration is decreased its impact on the magnitude of drooping becomes less significant. For wall structures printed in simulated Lunar or Martian gravity regimes, the total structure height was found to be similar to that of a structure printed under Earth's gravitational conditions. In contrast, for prints performed in microgravity, it was found that slumping was significantly reduced and structure height was larger. These results provide experimental data to enable the design and optimization of appropriate structures and tool paths for printing objects using DIW for off-planet manufacturing.

Exploring the influence of social capital on innovation networks in emerging industries: the mediating role of knowledge sharing

ABSTRACT In the face of rapidly evolving global markets, understanding the drivers of innovation network in emerging industries is crucial. Drawing on cooperative patent data from China’s new energy vehicle (NEV) industry from 2001 to 2019, this study uses social network analysis (SNA) and the quadratic assignment procedure (QAP) to empirically assess the effects of social capital on the innovation networks of emerging industries. The results revealed that during the growth and prosperity periods, the bonding structure has a positive impact on the formation of cooperative relationships, and the bridging structure has no effect. Cognitive and relational capital have continuous and significant positive impacts on the formation of cooperative relationships. In addition, knowledge sharing plays a significant mediating role in the process through which social capital affects innovation networks. This study not only advances our understanding of the dynamics within emerging industries but also provides valuable insights for policymakers and industry leaders seeking to foster innovation-driven growth. The implications of these findings are particularly pertinent in guiding strategic decision-making and policy formulation in sectors akin to the NEV industry.

Gelation of copolymers of acrylamide and sodium acrylate upon coordination with Cu2+ ions in concentrated solutions

The phase state of Cu2+ complexes with acrylamide and sodium acrylate copolymers at different copolymer concentrations and components molar ratios was studied. The change in complex stoichiometry from 2 to 3 carboxylate groups per Cu2+ ion was detected with an increase of copolymer concentration. In the concentrated solutions of copolymers, gelation is observed upon addition of Cu2+ ions, with the lowest concentration of copper required for gelation decreasing with the increase in copolymer concentration. These hydrogels are attributed to the formation of meta-stable inter-polymer metal complexes, which are able to persist due to a low segment mobility. The phase separation of complexes is shown to be associated with the bidentate coordination of carboxylate groups to Cu2+ ions, while the hydrogels formed in concentrated solutions mostly consist of bridging structures. Gelation threshold corresponds to the second critical concentration of poly(acrylamide-co-sodium acrylate) and is lower for copolymers with the higher molecular weight. Low acrylate content in the copolymers prevents collapse of the hydrogels caused by the salting-out effect. A higher gel content can be reached by increasing the copolymer concentration or the molar ratio of copper ions to carboxylate groups, with the latter reducing the swelling degree.

Stable hydrogen evolution reaction at high current densities via designing the Ni single atoms and Ru nanoparticles linked by carbon bridges

Continuous and effective hydrogen evolution under high current densities remains a challenge for water electrolysis owing to the rapid performance degradation under continuous large-current operation. In this study, theoretical calculations, operando Raman spectroscopy, and CO stripping experiments confirm that Ru nanocrystals have a high resistance against deactivation because of the synergistic adsorption of OH intermediates (OHad) on the Ru and single atoms. Based on this conceptual model, we design the Ni single atoms modifying ultra-small Ru nanoparticle with defect carbon bridging structure (UP-RuNiSAs/C) via a unique unipolar pulse electrodeposition (UPED) strategy. As a result, the UP-RuNiSAs/C is found capable of running steadily for 100 h at 3 A cm−2, and shows a low overpotential of 9 mV at a current density of 10 mA cm−2 under alkaline conditions. Moreover, the UP-RuNiSAs/C allows an anion exchange membrane (AEM) electrolyzer to operate stably at 1.95 Vcell for 250 h at 1 A cm−2.

Boric acid-regulated gelation and ethanol-assisted preparation of polybenzoxazine aerogels

Polybenzoxazine aerogels have gained widespread attention in recent years, but the prevalent use of hazardous solvents in the preparation process has severely impeded their further development and promotion for practical applications. Herein, using ethanol as a solvent, a strategy of boric acid-induced microstructure regulation is proposed to construct boron-doped polybenzoxazine (BPBz) aerogels, which provides a feasible approach to overcome the above situation. The introduction of boric acid enhances the backbone strength by forming intermolecular bridged structures between PBz chains and allows the use of ambient pressure drying. The resulting BPBz aerogel demonstrates high stiffness (specific modulus up to 255.97 kN·m·kg−1), low bulk density (0.203 g·cm−3), and low thermal conductivity (0.043 W·m−1·K−1), exhibiting excellent fire resistance when exposed to a 1200 °C flame (the self-extinguishing interval less than 1 s). More interestingly, the aerogel demonstrates intrinsic and tunable wettability that correlates with the morphology. Combining the environmentally friendly preparation strategy and these advantages, BPBz aerogels hold promise for thermal management and fire protection applications in energy-saving construction and other harsh conditions.

Solid-State Emissive Pillar[6]arene Derivative Having Alternate Methylene and Nitrogen Bridges.

Macrocyclic arenes show conformational adaptability, which allows host-guest complexations with the size-matched guest molecules. However, their emission properties are often poor in the solid states due to the self-absorption. Herein, we newly synthesized pillar[6]arene derivatives having alternate methylene and nitrogen bridging structures. Solvatochromic study reveals that the nitrogen-embedding into the cyclic structures can strengthen the intramolecular charge transfer (CT) nature compared to that of the linear nitrogen-bridged precursor. Owing to the large Stokes shift in the solid state, one of the nitrogen-embedded pillar[6]arenes shows high absolute photoluminescence quantum yield (ΦPL=0.36). Furthermore, it displays a turn-off sensing ability toward nitrobenzene (NB) vapor; a fluorescence quenching is observed when exposed to the NB vapor. From the structural analysis before and after the exposure of NB vapor, the amorphous nitrogen-embedded pillar[6]arene efficiently co-crystallize with NB and formed non-emissive intermolecular CT complexes with NB.