Vanadium (V) is an important rare metal element that is widely applied in a variety of fields. It is necessary to develop an efficient method for the utilization of V-bearing shale ore. In this work, we investigated the mechanism of enhanced vanadium extraction from shale ore by suspension oxidation roasting (SOR) by comparing the leaching behavior between traditional direct acid leaching and SOR-acid leaching. After being roasted, the V leaching rate obviously increased from 60.33 % to 83.20 % while the H2SO4 dosage, leaching temperature, and leaching time decreased 20 wt%, 30 °C, and 5 h, respectively. The non-appearance of CaF2 alleviated environment pollution from wastewater. Roasting activation improved the chemical reaction activity and transformed the dense structure into a loose and porous structure which contributed to improving the diffusion rate of acid into particles and the solutions. Kinetic studies shown that SOR contributed to decrease the activation energy of leaching system and solid layer or solution boundary layer diffusion contributed to the control of roasted product leaching rate.