In general, the laminated composite plates and stiffeners may exhibit the bending-extension coupling effect with the transverse shear deformations significantly induced. In this paper, for the first time we develop the associated boundary element method (BEM) for bending-extension coupling shear deformable laminated composite plates with multiple beams attached as stiffeners. Based upon the first order shear deformation theory, the individual boundary integral equations (BIEs) for plates and stiffeners are obtained from their corresponding matrix-form basic equations. To account for perfect bonding conditions between plate and stiffeners, we establish displacement continuity and interaction load equilibrium relations at their interfaces. To calculate the domain integrals related to unknown interaction loads, we discretize each stiffener into a series of cells using quadratic interpolation. By collecting the individual BIEs for plates and stiffeners and employing the continuity and equilibrium relations at the interfaces, we construct the entire system of linear equations to solve for all the unknown nodal quantities. Additionally, the complete solutions at the plate boundary, at internal points or along a stiffener are provided. The correctness of our present BEM formulation is verified through two representative examples by comparison with the commercial finite element software ANSYS. The numerical results demonstrate that our BEM formulation surpasses the conventional finite element method and is highly desirable for general stiffened laminated plates with bending-extension coupling and transverse shear deformations.