M any psychiatrists wonder if psychiatry has sowed seeds in the past that will destroy its future. Some think it may be torn apart in a civil war between neurobiological research and psychodynamic or psychosocial extremists. The expanse of the specialty is great, and difficuk to protect. As we understand more about the neural bases of mental illnesses/the boundaries between psychiatry and neurology become more permeable. Some fear psychiatry may abandon or lose its identity altogether, transplanted to the realm of clinical psychology. Psychopharmacological management, a complex skill that requires specialty training, is sometimes done by family practitioners. Will there be anything left of psychiatry 50 years from now? Or will a few psychiatrists remain, writing increasingly large numbers of prescriptions for patients they see for increasingly short periods of time? Despite this pessimistic scenario, I believe that psychiatry has a great future. First, psychiatrists specialise in treating mental illnesses, diseases that may ultimately arise from brain but that are expressed as mind. Mental illnesses are among the most important medical diseases by any measure chosen: morbidity, mortality, economic cost, or cost in personal suffering. Mental illnesses may ultimately be understood on the -basis of brain mechanisms, but they afflict individuals who live in personal and social contexts, and treatment must be provided in those contexts. Understanding how schizophrenia arises from the brain does not equip one for talking with and caring for a delusional or suicidal person. Only psychiatrists are uniquely trained to work at the complex interface between brain, the individual, and society. Second, psychiatry has lost its aura of hopelessness, as newer and better treatments have been developed. Its therapeutic future is even more promising. At present psychiatrists are able to offer complete remission of symptoms to many patients who present with syndromes such as anxiety, panic, or depression, and substantial improvement to most others. Most patients with psychotic disorders now live in the community. New atypical neuroleptic drugs markedly reduce symptoms with minimal side-effects. The promise of early and rapid pharmacological intervention combined with sensitive psychosocial and psychotherapeutic treatments holds out substantial hope of effective reintegration into the community and the possibility of a productive life, Increasingly, pharmacological treatments are rationally rather than empirically derived, based on our rapidly growing knowledge of neurotransmitter distribution and function, signal transduction, neural circuits and systems, and cognitive neuroscience. The partnership between clinical and basic research in neuroscience has given psychiatry a solid foundation for understanding how treatments work. In the future, this will lead to Changing boundaries in psychiatry