In this paper, we consider a system of the q-deformed bosonic Tamm-Dancoff oscillators, whose spectrum has some exponential cutoff factors at high energies. We first investigate the q-calculus in the Tamm-Dancoff (TD) boson algebra, and within this framework, the q-derivative, q-integral and q-exponential function are introduced. Using these properties, we construct a new formalism for the q-deformed quantum mechanics, which accordingly involve the q-adjoint operator and the q-Hermitian operator properties. We then derive the q-deformed Heisenberg relation, and develop the q-Hermitian momentum operator. The q-deformed Schrödinger equation is introduced, and as applications, we study the momentum eigenfunction and one-dimensional box problem. Another application of the TD type deformation onto lattice oscillations is also discussed through a model of the q-deformed Debye solid. Finally, other potential applications of the TD-oscillators gas model are concisely pointed out.