Borax Solution Research Articles

Stress-controlled medium-amplitude oscillatory shear (MAOStress) of PVA–Borax

We report the first-ever complete measurement of MAOStress material functions, which reveal that stress can be more fundamental than strain or strain rate for understanding linearity limits as a function of Deborah number. The material used is a canonical viscoelastic liquid with a single dominant relaxation time: polyvinyl alcohol (PVA) polymer solution cross-linked with tetrahydroborate (Borax) solution. We outline experimental limit lines and their dependence on geometry and test conditions. These MAOStress measurements enable us to observe the frequency dependence of the weakly nonlinear deviation as a function of stress amplitude. The observed features of MAOStress material functions are distinctly simpler than MAOStrain, where the frequency dependence is much more dramatic. The strain-stiffening transient network model was used to derive a model-informed normalization of the nonlinear material functions that accounts for their scaling with linear material properties. Moreover, we compare the frequency dependence of the critical stress, strain, and strain-rate for the linearity limit, which are rigorously computed from the MAOStress and MAOStrain material functions. While critical strain and strain-rate change by orders of magnitude throughout the Deborah number range, critical stress changes by a factor of about 2, showing that stress is a more fundamental measure of nonlinearity strength. This work extends the experimental accessibility of the weakly nonlinear regime to stress-controlled instruments and deformations, which reveal material physics beyond linear viscoelasticity but at conditions that are accessible to theory and detailed simulation.

Forensic analysis of hydrogen sulfide poisoning cases: Innovative LC-MS/MS methodology for accurate detection in human blood

Identification of hydrogen sulfide poisoning cases has long been a challenging issue in the field of forensic science. Due to the relatively limited histopathological features associated with hydrogen sulfide poisoning, traditional anatomy faces difficulties in accurately determining such cases. Additionally, existing detection methods have inherent limitations, including complex analytical processes and low sensitivity. This research uses the principle of the reaction between triazine and hydrogen sulfide to generate thiadiazine to measure hydrogen sulfide levels in the blood, applying this method to practical case examinations. A 0.2 mL blood sample is taken and diluted with 0.8 mL saturated borax solution. In a test tube, 1 mL acetonitrile solution containing 0.1 % formic acid is taken, followed by the sequential addition of 0.1 mL diluted solution and 0.1 mL 1 % triazine aqueous solution. After thorough mixing, the mixture is allowed to stand for 30 min, during which hydrogen sulfide undergoes a derivative reaction with triazine, producing thiazine. Subsequently, the sample undergoes centrifugation and membrane filtration, and the resulting solution is analyzed using Liquid Chromatograph Mass Spectrometer. The results reveal a strong linear relationship of hydrogen sulfide within the concentration range of 10 to 2000 ng/mL, with an R2 of 0.9989. The detection limit is 3 ng/mL, and the quantification limit is 10 ng/mL. In six cases of hydrogen sulfide poisoning, the presence of hydrogen sulfide in the blood of all deceased individuals is detected, with concentrations ranging from 0.25 to 0.79 μg/mL. For the first time, this study establishes an LC-MS/MS method for determining hydrogen sulfide in blood, meeting the detection requirements for hydrogen sulfide poisoning cases.

Natural flavonols as probes for direct determination of borax: From conventional fluorescence analysis to paper-based smartphone sensing

Borax is strictly regulated in the food processing and pharmaceutical industry due to its physiological toxicity, and the development of a direct analytical method is essential for effectively monitoring the borax abuse. In this work, the fluorescence properties of flavonoids, including flavones, isoflavones and flavonols, were systematically investigated from aqueous to borax solutions, and it was found that the weak intrinsic fluorescence of flavonols could be pervasively sensitized by borax. A natural flavonol, morin, was subsequently chosen as a representative probe to develop a turn-on fluorescence sensing method for borax analysis, which achieved a linear response spanning four orders of magnitude with a detection limit of 1.07 μM (0.22 μg mL−1 in terms of Na2B4O7 content). Furthermore, a smartphone-assisted paper-based test device was designed and constructed by 3D printing technology. Using morin-impregnated test strips as the carrier, the borax could be visually detected by the RGB signals of the captured images, with a detection limit of 0.13 mM (27.05 μg mL−1 for Na2B4O7). Combining ion exchange treatment for food samples and sodium periodate oxidation for drug samples, the developed methods were successfully applied for the direct analysis of borax in various products with the recoveries of 86.9–106.3% for traditional fluorescence analysis and 82.7–108.8% for smartphone-assisted fluorescence sensing. The fluorescence property of the morin-borax system was studied using time-dependent density functional theory, and the sensing mechanism was discussed in conjunction with experimental research.

A comparison of maceration methods for the preparation of infant skeletal remains for forensic anthropological analysis

Very little literature currently exists prescribing which maceration method to use when preparing infant human remains, resulting in bone quality that is suitable for forensic anthropological analysis. The aim of the study was to test five maceration methods to determine which is most suitable for infant remains for forensic anthropological analysis. The sample included five neonate pig carcasses (Sus scrofa domesticus), ranging between one to three days old. Five maceration methods were tested on the pig carcasses (one pig per maceration method) to determine their effectiveness. The methods included invertebrate maceration by meal worms, chemical maceration by bleach, chemical maceration by borax solution, enzymatic maceration by laundry detergent and sodium carbonate solution, and chemical maceration by sodium hypochlorite. A scoring method was created to assess the effectiveness of each maceration method. Invertebrate maceration and chemical maceration using bleach were the least successful methods of maceration (total maceration score = 8 respectively). Chemical maceration using borax and chemical maceration using sodium hypochlorite achieved complete maceration of the skeletal remains; however, they both resulted in artifacts that are unsuitable for forensic analysis (total maceration score = 14 respectively). Enzymatic maceration using laundry detergent and sodium carbonate was the most successful method (total maceration score = 17). The detergent technique subsequently successfully macerated all five sets of infant human remains. This study has validated that the enzymatic maceration technique using laundry detergent and sodium carbonate can be used to effectively macerate the remains of infant skeletal remains for forensic anthropological analysis.

Dual-network hydrogels based on dynamic imine and borate ester bonds with antibacterial and self-healing properties.

Polymeric hydrogel materials with multiple functions are in great demand in practical biomedical scenarios. In this work, a self-healing hydrogel with both antimicrobial properties was prepared using a strategy that combines dynamic imine and borate ester bonds. In this hydrogel, polyvinyl alcohol (PVA) is used as the base network, and borax solution as the cross-linking agent, and borate ester bonds can be formed between these two. Dialdehyde carboxymethyl cellulose (DCMC) was selected to cross-link with the amino groups in carboxymethyl chitosan (CMCS) and polyethyleneimine (PEI) to form dynamic imine bonds. The PVA/PEI/DCMC/CMCS hydrogels prepared by double chemical cross-linking have good mechanical properties (maximum tensile strength up to 289 KPa and strain at the break up to 1025%). Due to the uniqueness of the two chemical bonds, the hydrogel material is self-healing at room temperature without additional stimulation. In addition, the inherent antibacterial properties of the raw materials in this hydrogel confer antibacterial properties, with a kill rate of up to 99% against E. coli and S. aureus. The multifunctional hydrogels developed in this study provide more ideas and references for the future application of hydrogel materials in practical scenarios.

Bamboo Hitchhiking Point Project for the Federal University of Lavras - Minas Gerais, Brazil

The NEMATENC-UFLA began studies on bamboo during the pandemic to disseminate the use of this millennial material in construction. For this purpose, a prototype was developed for the shelter of a hitchhiking point, located on the university campus. The planning was developed in several stages. Initially, live transmissions were organized with professionals and researchers of the bamboo species existing in the university. The projects were developed for the species Dendrocalamus asper and Bambusa tuldoides. After the cuts, the treatment adopted was immersion in a solution of borax, boric acid, and copper sulfate. The pieces were stored on pallet racks designed for this purpose. After the execution of the foundation, it was assembled on site. The entire executive process had the theoretical and practical training of MSc. CE Frederico Rosalino: reduced model; cutting of plug-in connections; use of the “Vellez System” in the pillar bases; and covering with a sandwich of esterillas and waterproofing blanket. Students, engineering professionals, and others, participated in the construction. The whole process had the support of PROINFRA and collaborators. The result reached the proposed goal: promote the aesthetics and physical-mechanical properties of bamboo, besides offering comfort to the users of the university campus.

Spectral and theoretical analysis of derivatives of 1,2,3,3-tetramethyl-3H-indolium iodide (TMI), a highly selective derivatization reagent of cyanide, and their utility for the analysis of cyanide concentrations in beverages.

We develop a specific derivatization gas chromatography-mass spectrometry (GC-MS) method for cyanide using 1,2,3,3-tetramethyl-3H-indium iodide as the derivatization reagent. The derivative compounds were synthesized and characterized using 1H nuclear magnetic resonance (NMR), 13C NMR, and Fourier transform infrared (FT-IR) spectroscopy. The high selectivity of this derivatization for cyanide is supported by calculations and activation energy comparisons. We applied this method to pure water, green tea, orange juice, coffee cafe au lait, and milk. Derivatization was performed by diluting 20μL of sample solution with 0.1M NaOH and adding 100μL of saturated borax solution and 100μL of 8mM TMI solution, each drink was completed in 5min at room temperature, and selected ion (m/z = 200) monitoring analysis was linear (R2 > 0.998) at 0.15 to 15μM, with detection limits of 4-11μM were shown. This method is expected to be widely used in forensic toxicology analysis and can be applied to beverages, which are forensically important field samples.

EVALUASI PENGARUH PEMBERIAN BAHAN PENGAWET TERHADAP LAPISAN FINISHING EKSTERIOR KAYU PINUS DAN JATI RAKYAT

Woods that were placed outdoors were exposed to UV-induced photodegradation processes which damaged the lignin bonds in the wood resulting in the more susceptible woods against abrasion and weathering. This circumstance led to more finishing processes by applying paint to the wood surface carried out by industries and at the home level. Some finishing materials not only contribute to increasing the aesthetics of the wood surface but also increased the wood's resistance against harmful microorganisms. On the other hand, the resistance against pests did not increase as high as the resistance against outdoor weathering. In this study, pine woods and teak woods collected from the community forest were soaked in cold borax solution as a preservative agent before applying the paint to the wood surface. The treatments applied to the samples in this study were untreated control samples, preservative-treated samples, finishing-treated samples, and both preservative and finishing-treated samples. The results of this study showed that both teak and pine wood with preservative and finishing treatment were resistant to microbial damage (0% damage) after left 8 weeks of exposure in the outdoor area. However, there is a need to conduct further research with longer exposure time (1-2 years) to get more significant result differences between each treatment.

Synthesis of Composite Hydrogel Made of Woven Fabrics Stitched with PVA Yarn

In this study, a new method to prepare polyvinyl alcohol (PVA) hydrogel-based woven fabric composite is presented. In this method, the woven fabric was first stitched with PVA yarn and then subjected to the borax solution for simultaneously dissolving and crosslinking PVA. The prepared PVA hydrogel-based woven fabric composite was chemically, mechanically, and thermally characterized. FTIR analysis was performed to confirm the crosslinking of PVA on the reinforced fabric surface. X-ray diffraction analysis was carried out to investigate the crystallinity of the composite. An optical microscope was used to investigate the surface morphology of the composites. Moreover, a DSC analysis was done to investigate the thermal characteristics of the composite. The mechanical and fluid absorbency characteristics of the composite were analyzed to investigate the effect of the concentration of PVA yarn on the tensile strength and water absorbency of composites. The results showed that the tensile strength and rigidity of the composite increased by increasing the PVA yarn content in the composite.

Weathering of 3-component synthetic food cones: effects on residual amount, release rate, and field capture of 3 pest species of fruit flies (Diptera: Tephritidae).

Food-based baits are an important component of trapping networks designed to detect invasive tephritid fruit flies (Diptera: Tephritidae). An aqueous solution of torula yeast plus borax (TYB) is widely used, but synthetic food lures have been developed to facilitate field procedures, ensure standard composition, and lengthen the interval of bait attractiveness. Cone-shaped dispensers, containing ammonium acetate, putrescine, and trimethylamine (so-called 3C food cones), are currently being used in some large-scale trapping systems (e.g., Florida). Prior work in Hawaii showed that traps baited with 3C food cones capture similar numbers of Mediterranean fruit flies (medflies), Ceratitis capitata (Wiedemann), as TYB-baited traps after 1-2 wk of weathering but capture fewer medflies thereafter. In addition, 3C food cones attract fewer oriental fruit flies, Bactrocera dorsalis (Hendel), and melon flies, Zeugodacuscucurbitae (Coquillett) than TYB even when the food cones are freshly deployed. The current study describes an additional trapping experiment that expands upon earlier work by (i) presenting 3C food cones either unbagged (as done previously) or in nonporous or breathable bags to possibly reduce volatilization and lengthen bait effectiveness and (ii) measuring the content of the 3 components over time to potentially associate fruit fly captures with the loss of these food cone constituents. Implications of these findings for fruit fly surveillance programs are discussed.

Perception of artisans towards bamboo preservation for improved product durability in Uganda

Bamboo continues to attract attention globally as a sustainable material and is used in many applications. However, the quality of bamboo products in Uganda remains poor and cannot compete in the local and international markets. Bamboo's low product quality is associated with poor raw material processing and limited preservation methods, which lead to the short service life of the products due to its susceptibility to bio-deterioration and degradation. To cope with the above, artisans in Uganda apply various preservation methods depending on their knowledge and available resources. In this paper, the authors seek to determine the methods used by the artisans to preserve bamboo, understand the background of their intention to preserve, and their perception towards bamboo preservation. The Theory of Planned Behaviour was used as the main framework to understand artisans' perceptions towards the intention to preserve bamboo. A cross-sectional survey with 186 randomly selected artisans working with bamboo was conducted across three agroecological zones presumed to be Uganda's main bamboo growing areas. The study reported 13 available bamboo species, with the artisans exploiting mainly three of these species. Most artisans (86%) were aware of the need to preserve bamboo, with 67.4% practising bamboo preservation. The artisans use different methods and chemicals for preservation, i.e. leaching (17%), smoking (14%), soaking in crude lake salt (31%), boric acid and borax solutions (20%), surface application (16%), and pressure treatment (1%). Ordinal logistic regression was used to model artisans’ intention to engage in bamboo preservation. Attitude and subjective norms were the psychological factors that significantly influenced artisans’ intention to preserve bamboo. Interventions that increase benefits accrued from preserved bamboo can improve artisans’ attitude and subjective norms and enhance their intention to engage in bamboo preservation.

Quality by design-based capillary electrophoresis method development for the quantitative analysis of four iridoid compounds in Gentiana macrophylla Radix.

In this study, the capillary electrophoresis-photodiode array detector was employed for the analysis of four iridoid compounds in Gentiana macrophylla Radix (RGM), and the method was optimized based on the concept of analytical quality by design (AQbD). The peak areas relative standard deviation (n=3) and resolution of the four analytes were selected as critical method attributes. Fractional factorial design test combined with Pareto analysis were employed to screen critical method parameters (buffer concentration, pH, sodium dodecyl sulfate [SDS] micelle concentration, temperature, and voltage). Subsequently, three main factors (buffer concentration, buffer pH, and SDS concentration) were selected by central composite design test for constructing the design space. The optimal separation conditions as follows: capillary column (50.2cm×50µm, detection length 40cm). Working background electrolyte consisted of 51mmol/L borax solution (pH=9.47) and 40mmol/L SDS. The samples were injected by pressure (5s at 0.5psi) and the detection was performed at 254nm. Applied voltage was 20kV and column temperature was 23°C. The developed method is rapid and reliable for the quantitative analysis of four iridoid compounds in RGM, providing a reference for the application of AQbD concept in the analysis of natural products.

Borax analysis with spectrophotometry on meat bakso of frozen food that sold in modern markets and traditional markets in Palembang

Meatballs are one of the processed meat products that are in great demand by all levels of society. Along with the times and changes in public consumption trends, currently meatballs are turning into frozen food which is more simple and practical for cooking anytime. As processed frozen meat, making frozen food meatballs are often added with food additives (BTP) to maintain food quality such as preservatives, thickeners, and dyes. Borax is a dangerous chemical that is often added to food as a thickening agent. This study aims to determine and compare frozen food meatballs sold in modern markets and traditional markets in Palembang City which contain borax based on physical tests and to analyze borax levels using UV-Vis spectrophotometry. In this study, the maximum wavelength obtained to measure the absorbance of the 10 samples that have been prepared is 423,50 nm. Determination of the standard borax solution curve that has been made with various concentrations were 5 ppm, 10 ppm, 20 ppm, and 30 ppm. The obtained linear equation y = 0,0352x + 0,2047 with coefficient correlation (r) 0,9631. The levels of borax contained in the frozen food meatballs as the research samples were sample A contained 13,322 µg/ml, sample B contained 9,392 µg/ml, sample C contained 12,688 µg/ml, sample D contained 23,379 µg/ml, sample E contained 29,127 µg /ml, sample F was 24,821 µg/ml, sample G was 17,583 µg/ml, sample H was 15,595 µg/ml, the sample I was 26,665 µg/ml, sample J was 12,460 µg/ml. Based on physical tests, the characteristics of frozen food meatballs containing borax showed a brighter color, an unnatural smell, very chewy, and hard texture that is difficult to destroy. In conclusion, the ten samples of frozen food meatballs tested all contained borax with varying levels.

Preservation of muscle tissue with a formaldehyde-free borax solution for gross anatomy lessons

It is known that formaldehyde has serious toxicological effects on medical students, laboratory workers and environmental health. Recently various scientists search for a safe preservation fluid instead of the formaldehyde. One of them and the famous one is the Thiel’s embalming solution. However, it has been realized that it causes deterioration in muscle tissues. It was determined that this deterioration was caused by the boric acid. In the present study, previously formalin fixed muscle tissues were stored into the alkali form of boron during 40 days. At the end of the trial the appearance of the borax stored cadavers was quite similar to the formalin stored cadavers. In cross-sections taken from the muscle tissues, no deterioration could observe. Additionally, there was no putrid odor; on the contrary, a slight level of formaldehyde odor. In microbiological tests, there was a slight insignificant increase in the total number of bacteria in borax solutions. As a result, it was concluded that borax could be used as a cadaveric storage solution, and it can be more appropriate to use borax instead of boric acid in Thiel's solution.

Preservation of muscle tissue with a formaldehyde-free borax solution for gross anatomy lessons

Preservation of muscle tissue with a formaldehyde-free borax solution for gross anatomy lessons

Effect of Seed Priming and Coating through Micronutrient Application on Growth and Seed Yield of Groundnut (Arachis hypogaea L.)

Groundnut (Arachis hypogaea L.) is a major oilseed crop which ranks 3rd among the oilseed crops of the world. It is one of the chief vegetable oil sources in the world. The kernel of groundnut contains 46-52 per cent oil, 18 per cent carbohydrates and 25-30 per cent crude protein. Micronutrients are vital for plant growth and human health. Soil and foliar applications are the most prevalent methods of micronutrient addition. However, the cost involved and difficulty in obtaining high quality micronutrient fertilizers are major concerns with these in developing countries. Micronutrient seed treatments, which include seed priming and seed coating, are an attractive and easy alternative. So, the aim was to provide micronutrient fortified seed to the farmers for better yield advantage. A field experiment was conducted during Rabi season of 2018-19 and 2019-20 at the experimental farm, OUAT, Bhubaneswar to study the effect of seed priming and coating through micronutrient application on growth and seed yield of groundnut (Arachis hypogaea L.) with 21 different treatment combinations, laid out in Randomised Block Design (RBD) with three replications. Parameters measured were plant height, number of branches per plant, number of nodules per plant, days to 50% flowering, days to maturity and seed yield. The experimental findings revealed that the treatment (T17) seed priming with 0.5 g/l borax solution + 0.5 g/l sodium molybdate solution performed significantly (0.05 or 5% level) higher than other treatment i.e., plant height of 11.61 cm, 29.73 cm and 39.91 cm at 30, 60 and 90 DAS, numbers of branches per plant, i.e., 5.84, 7.41 and 9.10, number of nodules per plant 44.66, 57.76, and 29.88 at 45 DAS, 60 DAS and harvest time, least number of days to reach 50% flowering (25.57 days), least number of days to reach maturity i.e., 111.45 days and higher seed yield per hectare, i.e., 1565.70 kg ha-1. Molybdenum treatments recorded higher plant growth parameters as compared to boron application, whereas, boron application comparatively recorded higher yield attributing parameters and seed yield over molybdenum application. In general, seed priming treatments either with borax or sodium molybdate proved to be more effective than the seed coating treatments.

Tension‐Responsive Graphene Oxide Conductive Hydrogel with Robust Mechanical Properties and High Sensitivity for Human Motion Monitoring

PVA‐BB/GO‐Fe3+/agar hydrogels (BB is configured by 1:1 configuration of 0.04 mol L−1 boric acid solution and 0.04 mol L−1 borax solution) are designed with excellent mechanical and electrical properties due to their triple cross‐linked network, and they maintain stable performance in various tests, which is sufficient to support the use of hydrogels in multiple scenarios. Meanwhile, the tension responsiveness of the PVA‐BB/GO‐Fe3+/agar hydrogel allows it to rapidly transmit signal changes upon tension changes. Finally, maintaining increased energy dissipation and strength enhancement during the loading–unloading cycle provides the possibility of long, stable operation. In summary, it is believed that PVA‐BB/GO‐Fe3+/agar hydrogel has significant potential in the field of flexible sensors and is expected to be fabricated as a sensor for motion monitoring.

Determination of reducing carbohydrates in natural honey samples by optical micrometry method

The present article deals with the determination of the total amount of glucose and fructose in natural honey samples by the optical micrometry (OM) method. (Poly)vinyl alcohol spherical granules impregnated with a 0.05 mol/l borax solution were chosen as a sensitive element. It was shown that the formation of chelate esters of boron with polymer and carbohydrates is a pH-dependent process, and that the pH range 8.5–10.0 is the most appropriate for quantifying the total amount of reducing carbohydrates because glucose and fructose are undiscriminated. The impregnated polymer is not sensitive to the sucrose presence in the solution due to the absence of cis-diol fragments in it. Subsequently, the OM method was tested in the analysis of natural honey samples. The relative standart deviation in the case of OM method is less than 6%, and the results are similar to those obtained by the iodometric titration method. This makes the OM method suitable for laboratory-scale applications.

Detection of drug safety signal of drug-induced neutropenia and agranulocytosis in all-aged patients using electronic medical records.

We explored the adverse drug reaction signals of drug-induced neutropenia (DIN) and drug-induced agranulocytosis (DIA) in hospitalized patients and evaluated the novelty of these correlations. A two-step method was established to identify the relationship between drugs and DIN or DIA using 5-year electronic medical records (EMRs) obtained from 242 000 patients at Qilu Hospital of Shandong University. First, the drugs suspected to induce DIN or DIA were selected. The associations between suspected drugs and DIN or DIA were evaluated by a retrospective cohort study using unconditional logistic regression analysis and multiple linear regression model. Twelve suspected drugs (vancomycin, meropenem, voriconazole, acyclovir, ganciclovir, fluconazole, oseltamivir, linezolid, compound borax solution, palonosetron, polyene phosphatidylcholine, and sulfamethoxazole) were associated with DIN, and six suspected drugs (vancomycin, voriconazole, acyclovir, ganciclovir, fluconazole, and oseltamivir) were associated with DIA. The multivariate linear regression model revealed that nine drugs (vancomycin, meropenem, voriconazole, ganciclovir, fluconazole, oseltamivir, compound borax solution, palonosetron, and polyene phosphatidylcholine) and four drugs (vancomycin, voriconazole, ganciclovir, and fluconazole) were found to be associated with DIN and DIA, respectively. While logistic regression analysis revealed that palonosetron and ganciclovir were associated with DIN and DIA, respectively. Palonosetron and ganciclovir were found to be correlated with drug-induced granulocytopenia. The results of this study provide an early warning of drug safety signals for drug-induced granulocytopenia, facilitating a quick and appropriate response for clinicians.

On-Demand Removable Self-Healing and pH-Responsive Europium-Releasing Adhesive Dressing Enables Inflammatory Microenvironment Modulation and Angiogenesis for Diabetic Wound Healing.

Current diabetic wound treatments remain unsatisfactory due to the lack of a comprehensive strategy that can integrate strong applicability (tissue adhesiveness, shape adaptability, fast self-healability, and facile dressing change) with the initiation and smooth connection of the cascade wound healing processes. Herein, benefiting from the multifaceted bonding ability of tannic acid to metal ions and various polymers, a family of tannin-europium coordination complex crosslinked citrate-based mussel-inspired bioadhesives (TE-CMBAs) are specially developed for diabetic wound healing. TE-CMBAs can gel instantly (< 60 s), possess favorable shape-adaptability, considerable mechanical strengths, high elasticity, considerable wet tissue adhesiveness (≈40kPa), favorable photothermal antimicrobial activity, excellent anti-oxidant activity, biocompatibility, and angiogenetic property. The reversible hydrogen bond crosslinking and sensitive metal-phenolic coordination also confers TE-CMBAs with self-healability, pH-responsive europium ion and TA releasing properties and on-demand removability upon mixing with borax solution, enabling convenient painless dressing change and the smooth connection of inflammatory microenvironment modulation, angiogenesis promotion, and effective extracellular matrix production leveraging the acidic pH condition of diabetic wounds. This adhesive dressing provides a comprehensive regenerative strategy for diabetic wound management and can be extended to other complicated tissue healing scenarios.