Objective: To determine the association of academic performance with body mass index and gender among undergraduate physical therapy students.
 Study Design: Cross-sectional study.
 Place and Duration of Study: University of South Asia, Lahore Pakistan, from Mar to Aug 2019.
 Methodology: Three hundred and twenty-one students (either gender) were selected through consecutive sampling technique. Body mass index scale and cumulative grade point average was used to collect data.
 Results: The mean age of the study participants was 19.65±1.369 years, mean body mass index was 22.7±4.7 kg/m2, and mean cumulative grade point average was 3.0518±0.78. Overweight participants were 51(15.8%), and obese were 16(5.0%). A significant association of academic performance (cumulative grade point average) with body mass index and gender (p-value was <0.001). Females have good grades than males, with 16 males and 49 females with Grade-A, and 15 males and one female with Grade-D+.
 Conclusion: There was a significant association between academic performance (cumulative grade point average) with body mass index and gender. Female students had good grades than male students. High body mass index affects the academic performance of students.
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