Body Fat In Males Research Articles

Dietary sugar kelp consumption inhibits adipose tissue inflammation and fibrosis in male mouse model of diet-induced obesity

We previously demonstrated that consumption of U.S.-grown sugar kelp (Saccharina latissima) prohibits inflammation and fibrosis in the liver and white adipose tissue in male diet-induced obesity (DIO) mice. This study investigated whether sugar kelp can elicit similar benefits in female DIO mice. Male and female C57BL/6J mice were fed a low-fat (LF) control, a high-fat/high-sucrose/high-cholesterol (HF) control, or HF containing 6% sugar kelp (HF-Kelp) for 16 weeks. Body weight gain, serum triglyceride and total lipids, and glucose intolerance were decreased in male HF-Kelp compared with HF control. Furthermore, sugar kelp decreased gonadal white adipose tissue (gWAT) weight with smaller adipocytes and total body fat in males. In gWAT, male HF-Kelp exhibited less inflammation and fibrosis than the HF control, confirmed by histological analysis. Moreover, HF-Kelp increased physical activity only in males. Gut microbiome analysis showed sugar kelp elevated observed species and altered beta diversity in both males and females, suggesting changes in the gut microbiome may contribute to the effects of sugar kelp on gWAT inflammation and fibrosis. Therefore, our results demonstrate that sugar kelp consumption prevents obesity-induced inflammation and fibrosis in WAT in male mice, which is attributed, at least in part, to modest increases in metabolic rates, energy expenditure, and physical activity, and also modulating the gut microbiota.

Energy expenditure deficits drive obesity in a mouse model of Alström syndrome.

Alström syndrome (AS) is a rare multisystem disorder of which early onset childhood obesity is a cardinal feature. Like humans with AS, animal models with Alms1 loss-of-function mutations develop obesity, supporting the notion that ALMS1 is required for the regulatory control of energy balance across species. This study aimed to determine which component(s) of energy balance are reliant on ALMS1. Comprehensive energy balance phenotyping was performed on Alms1tvrm102 mice at both 8 and 18 weeks of age. It was found that adiposity gains occurred early and rapidly in Alms1tvrm102 male mice but much later in females. Rapid increases in body fat in males were due to a marked reduction in energy expenditure (EE) during early life and not due to any genotype-specific increases in energy intake under chow conditions. Energy intake did increase in a genotype-specific manner when mice were provided a high-fat diet, exacerbating the effects of reduced EE on obesity progression. The EE deficit observed in male Alms1tvrm102 mice did not persist as mice aged. Either loss of ALMS1 causes a developmental delay in the mechanisms controlling early life EE or activation of compensatory mechanisms occurs after obesity is established in AS. Future studies will determine how ALMS1 modulates EE and how sex moderates this process.

Body fat of competitive volleyball players: a systematic review with meta-analysis.

Reference values of body fat for competitive volleyball players are lacking, making it difficult to interpret measurement results. This review systematically summarized published data on the relative body fat of volleyball players and calculated potential differences between sex, measurement method, and competitive level. The protocol followed the Preferred Reported Items for Systematic Reviews and Meta-Analysis guidelines. The literature search was conducted using five electronic databases to retrieve all relevant publications from January 1, 2010, to July 1, 2021. The 63 studies including 2607 players that met the inclusion criteria were analyzed using random-effects models. Data were reported as pooled mean body fat with 95% confidence intervals. Body fat for males and females was 12.8% (11.9-13.8%) and 22.8% (21.9-23.7%), respectively. Body fat was 18.3% (16.3-20.4%) measured via skinfolds, 18.4% (15.6-21.2%) via bioelectrical impedance analysis, 24.2% (20.4-28.0%) via dual-energy x-ray absorptiometry and 21.6% (17.4-25.8%) via densitometry. Regional, national, and international-level players had body fat values of 19.5% (17.8-21.2%), 20.3% (18.6-22.0%), and 17.9% (15.7-20.4%), respectively. When the meta-regression was adjusted for the variables sex, measurement method, and competitive level, a significant difference between sex (p < 0.001), dual-energy x-ray absorptiometry and skinfolds (p = 0.02), and national and international-level players (p = 0.02) was found. However, sensitivity analysis revealed that findings regarding measurement method and competitive level were not robust and should, therefore, be interpreted with caution. Despite the limitations of published data, this meta-analysis provided pooled values for body fat of male and female volleyball players for different competitive levels and measurement methods.

Diagnostic performance of anthropometric indicators used to assess excess body fat in adolescence.

Objective:To compare the performance of anthropometric indicators that identify excess body fat (BF) in adolescents.Methods:This is a methodological study that used probability cluster sampling through school and class draws. Data collection included sociodemographic characteristics and anthropometric measures. Body mass index (BMI), waist-to-height ratio (WtHR), conicity index (C index), and waist circumference (WC) were calculated. Body fat percentage (BF%) was calculated from skinfold thickness and used as the gold standard. To analyze the data, descriptive statistics, Student’s t-test, Receiver Operating Characteristic (ROC) curve, and Youden’s index were used, in addition to correlation coefficient calculation between the indicators and BF%.Results:A total of 997 adolescents enrolled in municipal secondary schools participated in the study. By calculating the BMI, we found that 10.6% of adolescents were overweight, and 4.7% were obese. BMI, WC, and WtHR had the highest accuracy to predict body fatness. All the anthropometric indicators had higher specificity than sensitivity to diagnose excess BF in males. WC had the highest sensitivity in both genders. C index had the smallest area under the ROC curve and the lowest sensitivity in both genders, but its specificity was equivalent to that of the other indicators.Conclusions:BMI, WtHR, and WC were the best anthropometric indicators to predict excess BF in adolescents and had the best correlation coefficients. These tools can be considered in the screening to detect excess BF in adolescents.

Recent tendency of frailty and geriatric syndrome for elderly diabetic patients

Frailty, sarcopenia, geriatric syndrome and diabetes have been in focus. Several types of frailty are present from medical, psychological, and social points of view. The risk of developing diabetic frailty is 1.48 times for meta-analysis. By a systematic review of 15 studies, type 2 diabetes (T2D) patients showed higher sarcopenia risk with odd ratio (OR) 1.55. Concerning the relationship of senile frailty and body composition, male body fat mass correlated with frailty associated with cut off value of 27.6%. Protein intake amount per weight per day was divided into quartile groups. Hazard ratio of mortality for lowest/highest quartile was 2.26. In conclusion, geriatric syndrome may bring generalized various influence to each subject. For patient-centered practice of medicine, personalized medical practice would be required and recommended from now on.

Association of Body Composition With Serum Cholesterol and Body Mass Index in Healthy Pakistani Adults

Objective: To determine the association of serum cholesterol and body mass index with body composition in the healthy Pakistani adults.&#x0D; Study Design: Cross sectional study.&#x0D; Place and Duration of Study: Physiology Department, Army Medical College Rawalpindi/National University of Medical Sciences (NUMS), in collaboration with Armed Forces Institute of Rehabilitation Medicine (AFIRM) Rawalpindi and Clinical Pathology Laboratory (CPL), Pak-Emirates Military Hospital, Rawalpindi. (Duration to be asked form the authors).&#x0D; Methodology: The total study sample of 100 participants was taken, that comprised of two groups. Group-1 included male participants (n=50) while group-2 included female participants (n=50). The participants were healthy adults of ages 18-60 years having same physical activity background. Body composition of the participants was evaluated by bioelectric impedance analysis machine. Measurement of serum cholesterol was carried out by the Bosh Diagnostic Kit. Body Mass Index (BMI) was determined by the formula.&#x0D; Results: Serum cholesterol was found to be significantly correlated with body fat mass and percent body fat in males (r-value = 0.90 and 0.82, p-value &lt;0.001 and 0.002 respectively) and in females there was significantly positive correlation with the body fat mass (r-value=0.51, p-value 0.007), skeletal muscle mass (r-value = 0.59, p-value 0.005), total body water (r-value=0.67, pvalue 0.006) and fat free mass (r-value=0.47, p-value 0.008).&#x0D; Conclusion: Serum cholesterol and BMI were associated with the body composition in females but with only fat parameters in the males. .

Identifying Target Values of Body Composition for Preventing Frailty: A Descriptive Study in Older Adults.

This study investigated the relationship between frailty and body composition and the target values for preventing frailty in body composition. Frailty status and body composition such as the percent body fat and skeletal mass index was measured. Logistic regression analysis was performed by sex. Receiver operating characteristic curve was used to extract the cutoff values for body composition. The participants were 259 in females and 84 in males for 343 of which 75.5% females. Among the females, age was a significant independent variable. Percent body fat was significantly associated with frailty status in males, with a cutoff value of 27.6%. The area under the curve was significant (0.689, p < 0.01, sensitivity = 0.574, specificity = 0.784). New target value of percent body fat in males for preventing frailty is identified. Findings of this study could contribute to the establishment of preventive intervention for frailty in clinical practice.

The Effect of Polarized Training on the Athletic Performance of Male and Female Cross-Country Skiers during the General Preparation Period.

This study aimed to analyze the effect of 12 weeks of polarized training on body composition, cardiorespiratory function, and upper-body power of male and female cross-country skiers during the general preparation period. A total of 16 national cross-country skiers (8 male and 8 female; 8 national cross-country skiers and 8 national biathlon athletes) participated. Polarization training was conducted for 12 weeks from May to July in 2019 during the general preparation period for cross-country skiers. The low-weight, high-repetition method was used for strength training. The effect of the polarized training on body composition, maximum oxygen intake (VO2max), respiratory exchange rate, all-out time, and ski ergometer exercise time was assessed. There was no change in weight, BMI, and muscle mass in male and female cross-country skiers following the 12 weeks of polarized training (p > 0.05). Male body fat percentage (pre 18.1%, post 12.7%) and female body fat percentage (pre 29.1%, post 21.4%) showed a significant decrease (p < 0.05). After training, VO2max increased by 7.72% in male athletes (pre 71.05 mL/kg/min, post 77.0 mL/kg/min) and 6.32% in female athletes (pre 60.26 mL/kg/min, post 64.33 mL/kg/min). Treadmill exercise time increased by 5.39% for male athletes (pre 1038 s, post 1064 s) and 2.23% for female athletes (pre 855 s, post 874 s). However, there was no significant difference between male and female athletes (p > 0.05). The 50% recovery time from the maximum heart rate to the target heart rate decreased by 64.52% in males (pre 168.8 s, post 102.6 s) and 6.48% in females (pre 135 s, post 129.6 s). Significant differences were found only in male athletes (p < 0.05). The double-pole 500 m exercise duration for the ski ergometer significantly decreased after the training for both sexes (p < 0.05). In this study, the 12 weeks of polarized training improved the body composition and athletic performance of all cross-country skiers. Interestingly, in this study, we confirmed that polarized training had a better effect on cardiorespiratory function in male cross-country skiers than in female cross-country skiers. Conversely, we found that the outcomes of the ski ergometer exercise factors were more effective in female athletes than in male athletes. Therefore, we insist that when applying a polarized training program to athletes, it should be planned in detail by sex, exercise amount, intensity, and type of training.

Study of Obesity and Fat Distribution in Young Medical Students

The Body Mass Index (BMI) and body weight do not give enough information about a person’s body composition. Measuring the fat free mass gives us the extra information we need. The body composition can be measured in several ways. Unfortunately none of these techniques is a gold standard. That is why different techniques are combined in a full body composition assessment. This study aims to assess the prevalence of overweight, obesity and the fat distribution in medical students. Two hundred (200) preclinical, 100 male and 100 female age matched students (mean 18.93 ± 0.75 years) were included in the study. BMI, waist hip ratio, body fat, skeletal muscle mass and their bodily distribution were recorded by using an electronic body composition analyzer. The subjects were divided into undernourished (UN=BMI&lt;18.5 kg/m2), normal (N=BMI&gt;18.5–22.9 kg/m2), overweight (OW=BMI&gt;23-27.99 kg/m2) and obese (OB=BMI &gt;28 Kgm2) groups based on BMI cut off values for Asians. The data analyzed showed that 32% of the Male (mean BMI = 25.41 ±1.46 kg/m2) 33% of the Female (mean BMI =25.03 ± 1.44 kg/m2) were over weight and 16% of Males (mean BMI =31.08 ±1.91) 8% Females(mean BMI= 30.73 ± 1.66) were obese. The average total body fat in males was 20.75 ± 6.69% and 28.55 ± 5.86% in females. The total body fat was high in obese males and females 26.67±4.37, 36.73 ±0.46% respectively as compared to other groups. The visceral fat was high in obese males (14.40 ± 2, 27%) and whereas obese females had normal levels at (9.5 ± 1.0%). The subcutaneous fat was more in the lower limbs than in the trunk area in both males and females. The skeletal muscle mass was about 34.5 ± 3.44% in males and 26.98 ± 2.55% in females which was slightly less than the recommended values. The leg area had more muscle mass than other areas. The findings clearly indicate increase in total body fat increases with BMI and WHR.

Interrater reliability of novice examiners using A-mode ultrasound and skinfolds to measure subcutaneous body fat.

Examiners with minimal training and skill are often called upon to make body composition assessments using field methods. This study compared the interrater reliability of novice examiners for the skinfold (SKF) and A-mode ultrasound (US) methods of body composition assessment. Undergraduate Kinesiology majors (48 males, 32 females) with minimal training took both SKF and US measurements at three sites (males: chest, abdomen, thigh; females: triceps, suprailiac, thigh). Interrater reliability was significantly better for US compared to SKF at the thigh (ICCUS = 0.975, ICCSKF = 0.912) and abdomen (ICCUS = 0.984, ICCSKF = 0.693) for men and suprailiac (ICCUS = 0.978, ICCSKF = 0.883) for women. Additionally, interrater reliability of the US method was superior to the SKF method for the estimate of male body fat percentage (ICCUS = 0.990, ICCSKF = 0.862). The 95% CI was generally narrower for the US method than the SKF method at each site. The interrater reliability of the US method was superior to or equal to the SKF method for measuring subcutaneous body fat when novice examiners took the measurements.

Development and validation of body fat prediction models in American adults.

SummaryIntroductionCommonly used statistical models to predict body fat percentage currently rely on skinfold measures, anthropometric measures, or some combination of the two but do not account for the wide ranges of age and body mass index (BMI) present in the American adult population. The objective of this study was to develop a statistical regression model to predict in vivo body fat percentage (dual energy X‐ray) in men and women across significant age and obesity ranges.MethodsThis study included 228 adults between the ages of 21 and 70, with BMI between 18.5 and 40.0 kg m−2. The study population was split into training (n = 163) and validation (n = 65) groups, which were used to develop and validate the prediction models. The models were developed on the training group using a backwards stepwise regression analysis, with the initial predictors including age, BMI, and several anthropometric and skinfold measurements.ResultsThe final statistical regression models included age, BMI, anthropometric measures, and skinfold measures with significant effects following the stepwise process. The models predicted body fat percentage in the testing group with average errors of less than 0.10% body fat in males and females, while the four previously existing methods (Durnin, Hodgdon, Jackson, and Woolcott) significantly underestimated or overestimated body fat in both genders, with errors ranging between 2% and 10%.ConclusionsThe final models included hand thickness, and the female model was dependent on waist circumference and two of the skinfold measures, while the male model used hip and thigh circumferences, along with three skinfold measures. By including the skinfold measurements separately, instead of only as sums like previous models have done, these models can account for the different relative contributions of each site to total body fat.

Prognostic value of body weight loss and tissue components in patients with chronic heart failure and reduced left ventricular ejection fraction

The aim — to determine the prognostic value of weight loss (WL) and body tissue components in patients with chronic heart failure (CHF) and reduced left ventricular (LV) ejection fraction (EF).Materials and methods. We examined 77 patients with stable CHF aged 18 — 75 years, II — IV NYHA class, with LVEF £ 35 %. All patients underwent general clinical examinations and assessment of the component composition of the body using dual energy X‑ray densitometry.Results and discussion. The patients were divided into two groups depending on the WL for the last 6 months: the first group — patients with WL ³ 6 %, and the second group — WL &lt; 6 %. The first group had a significantly worse prognosis for the survival and onset of a combined critical event (death or hospitalization) compared to the second group. The prognostic value has been established regarding the survival of the muscle mass index of the extremities and the ratio of non‑adipose soft tissue and growth. The adipose tissue index and the percentage of body fat in males had a statistically significant effect on the risk of death. No prognostic significance of bone mineral mass relative to survival and the onset of a combined critical event was revealed.Conclusions. In patients with CHF and reduced LVEF, a loss of body mass i 6 % over the past 6 months, a low index of extremity muscle mass and a lower ratio of non‑adipose soft tissue and growth are associated with poorer survival. The adipose tissue index and percentage of adipose tissue correlate to survival in male patients. The indicators of the bone component did not demonstrate informativeness regarding the long‑term survival and the onset of the combined critical event in patients with CHF and reduced LVEF.

Comparing Alternate Percent Body Fat Estimation Techniques for United States Navy Body Composition Assessment

ABSTRACTAs a result of a Department of Defense (DoD) mandate, the U.S. Navy implemented its current body composition assessment (BCA) program in 1982. Despite the feasibility of the current program, its reliability, validity, and applicability have long since been called into question. As a result of these concerns, the Naval Health Research Center (NHRC) has conducted several research studies in the past to find a more accurate, affordable, and/or time-efficient body fat estimation technique. However, none of the NHRC studies resulted in changes to the Navy’s BCA program. The purpose of this study was three-fold: 1) evaluate the accuracy of the Navy’s current circumference measurement (CM) technique against an established criterion standard (i.e., Dual Energy X-ray Absorptiometry (DEXA)), 2) develop new CM regression equations based on DEXA measurements, and 3) determine if a simplified CM technique could be developed while still providing an accurate percent body fat estimation. The results of the study showed that using standalone DEXA measurements would increase the estimated percent body fat for males and decrease the estimated percent body fat for females as compared with the Navy’s current method. However, slight changes to the Navy’s CM sites and estimated percent body fat prediction equations could simplify testing procedures, provide Navy personnel with more accurate information in terms of their health risk, as well as maintain estimated percent body fat accuracy without any associated increases in terms of cost, training, or administration time.

Ecological momentary assessment of food perceptions and eating behavior using a novel phone application in adults with or without obesity

We developed a smart phone application to measure participants' food-reward perceptions and eating behavior in their naturalistic environment. Intensity ratings (0 - not at all to 10 - very strongly) of perceived anticipation of food (wanting) and food enjoyment at endpoint of intake (liking) were recorded as they occurred over a period of 14 days. Moreover, food craving trait, implicit and explicit attitude towards healthy food, and body composition were assessed. 53 participants provided complete data. Participants were classified by percentage of body fat; 33 participants with lower body fat (L-group) and 20 with higher body fat (H-group; ≥25% body fat for males and ≥32% for females). L-group participants reported 6.34 (2.00) food wanting events per day, whereas H-group participants recorded significantly fewer food wanting events (5.07 (1.42)); both groups resisted about the same percentage of wanting events (L-group: 29.2 (15.5)%; H-group 27.3 (12.8)%). Perceived intensity ratings were significantly different within the L-group in the order liking (7.65 (0.81)) > un-resisted wanting (leading to eating) (7.00 (1.01)) > resisted wanting (not leading to eating) (6.02 (1.72)) but not in the H-group. Liking scores (L-group: 7.65 (0.81); H-group: 7.14 (1.04)) were significantly higher in L-group than in H-group after controlling for age. Our results show that individuals with higher percentage of body fat show less food enjoyment after intake and reveal no differentiation in intensity ratings of perceived anticipatory and consummatory food reward. These results are consistent with a hypothesized reward deficiency among individuals with higher percentage of body fat.

The Current Conditions and Lifestyles of Obese University Students.

BackgroundThe prevalence of cardiovascular diseases in Japan remains high, and the onset becomes early. Studies on the current conditions and lifestyles of obese university students may support early interventions to achieve lifestyle modification.Methods and ResultsThe results of periodic health examinations in 32,262 first-year university students revealed that 2,036 (6.3%) were obese. We performed a more detailed examination in 221 of these obese students (165 males and 56 females, age 19 ± 1 years) with study agreement from 2014 to 2016. In this study cohort, the percentage of students who exercised regularly was significantly higher among males than females. Body fat in males with well-exercised was lower than that in males with no exercise. In addition, serum level of high-density cholesterol in males with well-exercised was higher. Among females, there were no significant differences in these parameters between exercisers and non-exercisers. Forty-two obese students (40 males and two females) met the diagnostic criteria of metabolic syndrome (MetS). Among males, levels of body fat, uric acid, liver enzyme and insulin resistance in the MetS group were significantly higher than those in the non-MetS group. The average ratio of eicosapentaenoic acid to arachidonic acid (EPA/AA) was low (0.14).ConclusionsAlthough the proportions of students with obesity and/or MetS were not high, the EPA/AA ratio in obese young males was low, which may be associated with a high risk of coronary atherosclerosis. To prevent the onset of cardiovascular diseases early intervention to achieve lifestyle modification may be important.

Cardiorespiratory fitness and its association with adiposity indices in young adults.

Objective:This study investigated the relationship between cardiorespiratory fitness (CRF) and adiposity in young adults.Methods:Data was collected from 133 students of a medical college of Pakistan. The study was conducted on young adults, aged 17-24 years, recruited from Jinnah Medical & Dental College, Karachi, between Aug-Dec, 2015. Queen’s College Step Test was conducted to measure CRF and maximal oxygen uptake (VO2max) evaluated. Anthropometric measurements (body mass index, body fat, visceral fat, waist circumference) were taken to assess adiposity. Associations of VO2max and adiposity were analyzed.Results:The prevalence of overweight/obesity was 44% overall. The VO2max (ml/kg/min) of males and females was 55.41±9.45 and 39.91±3.14, respectively, the gender difference being highly significant (p<0.001). Quartiles of VO2max showed strong inverse relationship between adiposity and VO2max, obese individuals having low VO2max (1st quartile) and normal weight individuals having high VO2max (4th quartile). VO2max correlated greatest with body fat in males (r = –0.600; p<0.001), and waist circumference in females (r = –0.319; p=0.004).Conclusion:The results indicate low CRF in young females and a strong inverse relationship between fitness levels and adiposity in young adults of both genders. Improving these parameters in our young population may prevent development of chronic non-communicable disease in later life.

Association between Obesity Indices and Insulin Resistance among Healthy Korean Adolescents: The JS High School Study.

ObjectiveTo investigate whether indices of obesity are associated with insulin resistance in Korean adolescents.MethodsThis study was conducted as a cross-sectional analysis of 817 healthy adolescents aged 15–16 years without diabetes. Percentiles group of weight-for-height, body mass index (BMI)-for-age, waist circumference (WC)-for-age, and skin fold thickness (SFT)-for-age were based on the 2007 Korean National Growth Charts. Percentiles of waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), and percent body fat were calculated for the study population. Insulin resistance was estimated by homeostatic model assessment (HOMA-IR). Logistic regression models were used to estimate odds ratio for insulin resistance according to seven obesity indices. Generalized linear models were used to assess the associations between obesity indices and continuous HOMA-IR levels.ResultsSex and age-adjusted odds ratios (95% confidence interval) for insulin resistance, defined as HOMA-IR>2.50, of the 75–94th and ≥95th percentiles of weight-for-height were 3.87 (2.38–6.30) and 11.37 (5.87–22.02), compared to the <50th percentile. Corresponding odds ratios were 3.27 (2.02–5.28) and 11.72 (6.05–22.73) for BMI-for-age, 4.72 (2.82–7.88) and 13.22 (6.42–27.23) for WC-for-age, 3.67 (2.27–5.94) and 13.58 (6.71–27.48) for WHR, 4.78 (2.99–7.67) and 12.84 (6.23–26.46) for WHtR, 2.62 (1.61–4.26) and 6.68 (3.46–12.90) for SFT-for-age, and 2.29 (1.33–4.26) and 10.06 (4.39–23.06) for body fat. These associations were more prominent when insulin resistance was defined as HOMA-IR>3.16 and were stronger in males than in females. Continuous measure of HOMA-IR was significantly associated with body weight, BMI, WC, WHR, WHtR, and SFT in both sexes (p<0.001), and with percent body fat in males only (p<0.001).ConclusionOur findings suggest that obesity indices are positively associated with insulin resistance in apparently healthy adolescents.

Identification of sex-specific thresholds for accumulation of visceral adipose tissue in adults.

ObjectiveThe purpose of this study was to measure the linearity of visceral adipose tissue (VAT) accumulation with measures of total body adiposity to determine if a threshold exists, and to explore the association with cardiometabolic risk factors in adults.Design and MethodsUsing a cross1sectional design, data were obtained from 723 adults (324 females) age 19-47 years. Body mass index ranged from 15-52 kg/m2. Segmented linear regression was used to identify sex-specific percent body fat thresholds at which VAT slope changes. Linear regression measured the association of VAT mass, total fat mass and subcutaneous fat with cardiometabolic risk factors above and below each threshold.ResultsAdiposity thresholds were identified at 23.4% body fat in males and 38.3% body fat in females beyond which the slope of VAT per unit of %body fat increased to strongly positive. Males and females above these adiposity thresholds had significant dyslipidemia (p<0.001), increased insulin resistance (p<0.001), and higher fat mass across all depots.ConclusionWe infer from these cross-sectional data that accumulation of VAT mass is not linear with increasing adiposity; increases in visceral accumulation above threshold are associated with decreased insulin sensitivity and cardiovascular risk in males and females independent of total body fat.

Studies of anthropometric indicators and their relationship with metabolic variables

The purpose of this work is to identify in the anthropometrical indicators used here in this study the percentage of body fat, the body mass index (BMI) and the waist-hip ratio (WHR), which present a correlation with the metabolic variables of heart rate, blood pressure (systolic and diastolic) and double product. A population of 69 subjects averaging 41.7 ± 6.6 years old had their data registered by applying the Bruce Protocol modified to calculate metabolic variables; to obtain the percentage of fat, the formula of Petroski was used. The data collected received statistical treatment by the “Statistical 5.0” program with correlation being made by the calculation of the simple coefficient of Pearson “r” by means of a statistical significance test (p rn of male body fat distribution (android) and blood pressure. The double-product had a major correlation with the BMI; however, this variable really reflects the work of the myocardium since the BMI is the only indicator used here that includes lean mass in its values. The time spent on the treadmill was correlated in a negative way only with the percentage of fat; in other words, the greater the percentage, the lesser time spent on the treadmill.

Vitamin D and calcium-sensing receptor polymorphisms differentially associate with resting energy expenditure in peripubertal children

Given that calcium metabolism is influenced by genes and is tightly linked to energy-utilizing pathways, this study evaluated the association of single nucleotide polymorphisms (SNPs) in the vitamin D receptor (VDR) and calcium-sensing receptor (CASR) with resting energy expenditure (REE). In 273 boys and girls, 7-12years of age, cross-sectional REE was measured via indirect calorimetry, body composition by DXA, and dietary measures by 24-h recall. SNPs for VDR Cdx-2 (rs11568820) and CASR A986S (rs1801725) were genotyped using the Illumina Golden Gate assay. Multiple linear regression models were used to determine the association between SNPs and REE. African American carriers of the 'A' VDR Cdx2 allele had increased levels of REE in the overall sample, and this association was apparent among participants with an adiposity level of <25% and 30% body fat in males and females, respectively. For CASR, an association between carriers of the 'A' allele and REE was observed only in those in the upper median of calcium intake. VDR and CASR variants are associated with REE in children and are influenced by levels of calcium intake and adiposity. Our results bring awareness to mechanisms underlying the regulation of REE and biological and dietary influential factors.