To effectively solve the problem of a small proportion of substantia nigra and midbrain regions in Magnetic Resolution Imaging (MRI) images of Parkinson’s disease (PD) patients, unclear boundaries with surrounding tissues, and difficulty in accurately delineating boundaries, an improved U2-Net algorithm for Parkinson’s substantia nigra midbrain image segmentation was proposed. This algorithm first improves the Residual U-blocks (RSU) and RSU-4F modules using the Shuffle Attention (SA) module, enhancing the network’s attention to Parkinson’s substantia nigra and midbrain blurry regions in the encoding and decoding layers. Next, replace some ordinary convolutions in RSU-4F with DynamicConv (DyConv), capture local features through dynamic convolution kernels, and improve the segmentation performance of Parkinson’s images. The experimental data used clinical data, and the improved algorithm achieved Dice, Precision, Recall, and mIou of 80.27%, 89.99%, 88.88%, and 82.38% in substantia nigra segmentation, respectively. The experimental results show that this algorithm can achieve more precise segmentation of Parkinson’s images.
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