Criteria For Blood Donation Research Articles

Plasma-derived product recipients' views on the acceptability of implementing a programme of plasma donation for fractionation from men who have sex with men.

Over the past few years in Québec, Canada, exclusion criteria for blood donation and plasma donation for fractionation have been modified. Héma-Québec, the institution responsible for blood products, has made changes to allow more inclusive access to blood and plasma donation, in accordance with evolving scientific data concerning donation safety. The study, conducted before those changes were implemented, aimed to assess acceptability of recipients and parents of recipients of plasma-derived products for men who have sex with men (MSM) to become eligible to donate plasma for fractionation. Eight qualitative interviews (4 focus groups, 4 individual) were conducted with a total of 17 plasma product recipients and parents of children needing plasma-derived products. Data were analysed using thematic analysis. Participants were rather favourable regarding acceptability of MSM as potential donors. Participants viewed this change as necessary and beneficial. They also felt they must rely on trust in Héma-Québec, conferred automatically or by default. However, some participants raised concerns about donation safety and reported feeling helpless regarding inclusion of MSM. The importance of being informed and that recipients' safety be prioritized first and foremost were also mentioned. Despite their nuanced attitudes, recipients showed high levels of acceptability of including MSM in plasma donation for fractionation. Actions can be taken to reduce concerns regarding the safety of products received.

Discursive History of Screening Criteria for Blood Donation Affecting Gay, Bi, and Other Men Who Have Sex with Men in Canada: 1983–2013

Background: In September 2022, Canadian Blood Services (CBS) implemented a sexual behaviour–based screening (SBBS) approach for all donors, putting an end to Canada’s “gay blood ban.” Analysis: To better understand the discursive history leading up to this change, this article analyzes articles in major newspapers and 2SLGBTQIA+ periodicals in Canada from 1983 to 2013 related to the ban. Conclusions and implications: The move to SBBS came about due not only to advancements in epidemiological knowledge and testing technologies, but also to significant shifts in how the issues were framed in public discourse.

Analysis of Blood Donor Deferral Pattern during COVID-19 Pandemic at a Tertiary Care Hospital-based Blood Centre, Jammu and Kashmir, India: A Cross-sectional Study

Introduction: Blood donor deferral is vital for ensuring safe blood transfusion. However, with the unfolding Coronavirus Disease-2019 (COVID-19) pandemic, significant changes were made in donor screening and blood donation criteria, resulting in a shift in the pattern of donor deferrals. Aim: To estimate the blood donor deferral patterns during the COVID-19 pandemic. Materials and Methods: A retrospective cross-sectional study was conducted in the Department of Transfusion Medicine at SMHS Hospital/GMC Srinagar, Jammu and Kashmir, India. The study spanned two years, from March 2020 to February 2022. All blood donors were screened in accordance with the Ministry of Health and Family Welfare (MOHFW), National Acquired Immune Deficiency Syndrome (AIDS) control organisation (National blood transfusion services) 2017 guidelines. The data was analysed in Microsoft Excel, considering factors such as age, gender, type of deferral, and reasons for deferral. Results: Deferred blood donors were most common in the age group of 18-33 years. During the study period, a total of 19,895 blood donors (19493 males and 402 females) were registered for blood donation. Out of these, 3441 donors (17.30%) were deferred, with a male donor deferral rate of 3258/19493 (16.71%) and a female donor deferral rate of 183/402 (45.52%). Temporary blood donor deferrals accounted for 3272 (95.09%) cases, while permanent deferrals were 169 (4.91%). The most common cause of deferral was low haemoglobin, accounting for 991/3441 (28.80%) cases, followed by deferrals due to reasons attributable to the COVID-19 pandemic (786/3441, 22.84%) and hypertension (653/3441, 18.98%). Conclusion: The study observed a substantial increase in the total donor deferral rate, as well as a change in the donor deferral pattern during the COVID-19 pandemic.

Phenotypic Profile of Kidd Blood Group System in Northern Pakistani Population

OBJECTIVETo investigate the phenotypic profile of Kidd blood group system in Northern Pakistani population.STUDY DESIGN: Descriptive cross-sectional PLACE AND DURATION OF STUDY: The research was conducted at department of immunohaematology, Armed Forces Institute of Transfusion (AFIT) Rawalpindi, Pakistan, from Dec 2022 to Jun 2023.METHODOLOGY: The study included 280 donors of all ages and both genders fulfilling the WHO Healthy Volunteer Donor criteria for blood donation. Individuals were included in this study while individuals not fulfilling the criteria were excluded from this study.. Blood grouping was performed by tube agglutination method and for data analysis version 23.0 of Statistical Package for Social Sciences (SPSS) was used.
 RESULTS: The frequencies of A, B, AB, and O antigens were (23.9%), (33.6%), (10.0%), and (32.5%), respectively among all the 280 participants while the frequencies of Kidd Jka and Jkb were 73.2% and 75.4% respectively. The expression of phenotypic profile was Jk ( a+b+) in 49.6%, Jk (a-b+) in 25.7%, Jk (a+b-) in 23.6%, and Jk (a-b-) in 1.1%.
 CONCLUSION: Kidd antigen was found in a significant proportion of our donor population which arises the need for undertaking extended antigen typing for this minor blood group as a routine in our blood banks to be able to provide antigen free blood units to chronically transfused, pregnant and anaemic individuals for prevention of delayed haemolytic transfusion reactions.

Knowledge, attitude, and practice among medical students in gaza strip towards voluntary blood donation: a cross-sectional study

BackgroundA major component of emergency medical care is blood. The Gaza Strip has faced repeated wars over the last few years, emphasizing the importance of blood donation even more. This study aims to assess medical students’ knowledge, attitudes, and practices regarding voluntary blood donation in Gaza (VBD).MethodsThis cross-sectional study used stratified sampling method to survey medical students at Gaza’s two medical schools, Al-Azhar and Islamic Universities, between March and April 2022. A 35-item self-administered questionnaire with four sections: demographics, knowledge, attitude, and practice, was used. The data were statistically analyzed using SPSS version 25.ResultsA total of 329 students were surveyed (response rate of 89.6%). The median age was 20 (IQR = 3). Males made up 44.7% of the sample. Overall, 54.7% were found to have good knowledge about VBD, 68.1% did not know the time-to-wait between each whole blood donation, and in terms of blood donation criteria, only 30.7%, 25.2% were aware of the appropriate age and weight for donating. Moreover, school was the source of most information (66.6%). Meanwhile, 73.3% of participants expressed a positive attitude toward VBD. Only (17,6%) did not show a willingness to donate blood regardless of their relationship with the recipient. The vast majority (83.3%) had never donated blood before, and 12.5% had no plans to do so in the future. The two most common reasons for this were the lack of opportunity and health issues (31.0%, 11.9%, respectively).ConclusionThe sampled medical students had a positive attitude toward VBD, but there were deficiencies in their knowledge of blood donation criteria, and most had not donated blood. Adequate awareness campaigns are required to increase awareness about this universally and locally important subject.

The impact of pre-donation viral markers screening of new blood donors on blood safety.

The risk of transfusion-transmissible infections (TTIs) remains a concern in transfusion medicine. Since the rate of infection among first-time blood donors is higher than repeated donors, strategies to enhance blood safety can focus on new donors. The aim of the study was to investigate the effect of pre-donation viral screening of new donors on blood safety. The pre-donation screening of new donors was implemented in the Kurdistan blood center. In this program, new donors who met the blood donation criteria were informed about the program and only a blood sample was donated for HBs Ag, HCV Ab, and HIV Ab testing. New donors with negative results were invited to donate blood after 12weeks. A unit of blood was collected from eligible returned donors. Laboratory tests were performed again using the same methods. Finally, the prevalence of confirmed positive TTI results among donated blood in Kurdistan blood center was compared before and after the establishment of program. During the study, 4,434 new donors were screened for viral markers. A total of 41 new donors (0.92%, 95% CI, 0.007-0.13) had repeatedly reactive results and infection was confirmed in blood sample of 24 donors (0.54%, 95% CI, 0.003-0.008). Overall, 56% of new donors returned for blood donation. Prevalence of confirmed TTIs markers in collected blood units was 0.27% and 0 before and after implementing program, respectively. This study indicated that Pre-donation screening can reduce the risk of TTI transmission by identifying infected donors at the pre-donation phase.

Prevalence and Association of Transfusion-Transmissible Infections with Age of Blood Donors: A Regional Transfusion Centre Study in Northern Pakistan.

To evaluate the prevalence and association of Transfusion-Transmissible Infections (TTIs) with age of blood donors in a regional transfusion centre located in Northern Pakistan. Descriptive study. Place and Duration of the Study: Armed Forces Institute of Transfusion, Rawalpindi, Pakistan, from January 2017 to December 2021. All blood donors who qualified institutional blood donation criteria were initially screened for HBsAg, Anti-HCV Ab, HIV antigen-antibody combination and syphilis by an automated chemiluminescent microparticle immunoassay analyzer (Architect Plus i 2000 SR, Abbott Diagnostics, Abbott Park, IL). Initially, all seronegative donor blood samples were subjected to nucleic acid amplification test (NAAT). All TTI-positive donors were immediately informed and counselled to consult the medical physicians for further treatment. Descriptive statistics and significance of association were determined. The prevalence of TTIs among blood donors was calculated to be 3.33% among 308,767 donors. HCV (1.4%) was the most prevalent TTI followed by syphilis (0.9%), HBV (0.68%) and HIV (0.26%), respectively. TTIs were most prevalent in the 26 to 35-year-old group, accounting for 5,143 (50.0%) positive donors (p<0.05). The prevalence of TTIs among blood donors was found to be 3.33%. HCV was the most common TTI, followed by syphilis, HBV, and HIV. The 26 to 35 year-old group had a significantly high prevalence of TTIs. Transfusion-transmissible infections, Hepatitis B virus, Hepatitis C virus, Human immunodeficiency virus, Treponema pallidum, Syphilis, Automated chemiluminescent microparticle immunoassay analyzer, Nucleic acid amplification test.

Evolving deferral criteria for blood donation in France: Plasma donation by men who have sex with men.

Since the advent of AIDS, men who have sex with men (MSM) have often been deferred from blood donation. In France, quarantine plasma donation by MSM donors with the same deferral rules as for other donors was introduced in July 2016 and continued up to March 2022. At this time, MSM-specific deferral criteria were lifted for all blood or plasma donation. The donor deferral, as well as rate of infectious markers in plasma donors who would have been otherwise deferred for MSM activity, was evaluated and compared with those of the other donors during the same time period from June 2016 to March 2022. A total of 8843 MSM donors made 12,250 plasma donation applications. The overall deferral rate was very high (75.2%), mainly due to the absence of apheresis capacity at the donation site. The deferral criteria for sexual risk were present in 12.1% of MSM donors compared with 1.0% in other plasma and blood donors (p < 0.001). Overall, 994 MSM donors made 2880 plasma donations. Of these,one donation was HIV positive (34.7 vs. 0.6/105 donations by other donors, relative risk [RR]: 61.0 [95% confidence interval [CI]: 8.5-437.7]), one was HBV positive (34.7 vs. 4.5/105 , RR: 7.7 [95% CI: 1.1-54.6]) and none were HCV positive (0 vs. 2.4/105 ). Additionally, 21 donations were syphilis positive (729.2 vs. 10.7/105 , RR: 67.9 [95% CI: 44.2-104.4]). A post hoc analysis of eligible MSM donors who were unable to donate plasma due to logistic constraints yielded similar findings. Plasma donation by donors who would have been otherwise deferred for MSM activity was associated with both an increased deferral rate for sexual risk and an increased rate of infectious markers, notably syphilis.

Horiba Micros ES 60 Blood Cell Analyzer in Blood Donor Eligibility: A Validation Study.

Eligibility criteria for blood donation require hemoglobin levels of ≥12.5 g/dL for women and ≥13.5 g/dL for men, and a platelet count of ≥180 × 109/L. Screening methods before donation should ensure high accuracy, precision, and ease in operation. We assessed the performance, precision, and repeatability of the Horiba Micros ES 60 (Horiba) compared to the Beckman Coulter DXH 800. Performance was compared by testing samples for each of the 11 devices across 6 sites in the Transfusion Service of Friuli Venezia Giulia Region, Italy. We measured precision by calculating the coefficient of variation (CV), concordance with ρ-Pearson's correlation coefficient, and accuracy with F-tests. The intra-assay agreement was examined in the 11 devices, and repeatability was performed by using CV and the Kruskal-Wallis test. The precision of Horiba was acceptable. Overall, ρ-Pearson's coefficients indicated a strong correlation and positive relationship between all variables. The Bland-Altman plots showed that most of the differences lay within the limits of agreement. All CV were below the reference threshold for all the parameters. Finally, the Kruskal-Wallis test reported non-significant statistical differences for all parameters, except platelet count (p &lt; 0.000). Horiba is adequate for routine pre-donation screening. The intra-assay agreement further demonstrates the accuracy of the device.

A randomized trial of blood donor iron repletion on red cell quality for transfusion and donor cognition and well-being

AbstractAlthough altruistic regular blood donors are vital for the blood supply, many become iron deficient from donation-induced iron loss. The effects of blood donation–induced iron deficiency on red cell transfusion quality or donor cognition are unknown. In this double-blind, randomized trial, adult iron-deficient blood donors (n = 79; ferritin < 15 μg/L and zinc protoporphyrin >60 μMol/mol heme) who met donation qualifications were enrolled. A first standard blood donation was followed by the gold-standard measure for red cell storage quality: a 51-chromium posttransfusion red cell recovery study. Donors were then randomized to intravenous iron repletion (1 g low-molecular-weight iron dextran) or placebo. A second donation ∼5 months later was followed by another recovery study. Primary outcome was the within-subject change in posttransfusion recovery. The primary outcome measure of an ancillary study reported here was the National Institutes of Health Toolbox–derived uncorrected standard Cognition Fluid Composite Score. Overall, 983 donors were screened; 110 were iron-deficient, and of these, 39 were randomized to iron repletion and 40 to placebo. Red cell storage quality was unchanged by iron repletion: mean change in posttransfusion recovery was 1.6% (95% confidence interval −0.5 to 3.8) and −0.4% (−2.0 to 1.2) with and without iron, respectively. Iron repletion did not affect any cognition or well-being measures. These data provide evidence that current criteria for blood donation preserve red cell transfusion quality for the recipient and protect adult donors from measurable effects of blood donation–induced iron deficiency on cognition. This trial was registered at www.clinicaltrials.gov as NCT02889133 and NCT02990559.

The role of mitral annular plane systolic excursion in prediction of acute blood loss in healthy voluntary blood donors

AimThe aim of this study is to compare the diameter of the inferior vena cava with mitral annular plane systolic excursion measurement in order to determine the volume loss before and after blood donation in healthy volunteers.Material and methodsThe study was a single-center, prospective, cross-sectional study which included 46 healthy blood donors donating in a tertiary care hospital’s blood bank. The inclusion criteria for the study were: volunteers aged 18–65 years, over 50 kg in weight, who met blood donation criteria, with hemoglobin values of >13.5 g/dL for males and >12.5 g/dL for females. After obtaining written consent, the systolic, diastolic, and mean arterial blood pressure along with the pulse rate of the donors were measured in standing and lying positions by the attending physician. Next, inferior vena cava and mitral annular plane systolic excursion measurements were made both pre and post blood donation.ResultsThe decrease in both inferior vena cava diameter and mitral annular plane systolic excursion values measured pre and post blood donation was found to be statistically significant (p <0.05). There was no difference between the other variables pre and post blood donation.ConclusionsOur study revealed that decreased inferior vena cava and mitral annular plane systolic excursion values correlated in determining blood loss post blood donation. Mitral annular plane systolic excursion may be useful to predict blood loss in the early stages of hemorrhagic shock.

COVID-19 outbreak may increase mortality rates in genitourinary cancers.

COVID-19 outbreak may increase mortality rates in genitourinary cancers.

Knowledge, attitudes and practices related to blood donation in a selected population in Jaffna

Poor knowledge and negative attitudes among the public regarding blood donation have resulted in insufficient availability of blood and blood products for transfusion procedures in many clinical settings. This study aims to assess knowledge, attitudes and practices related to blood donation and their associated socio-demographic factors in Jaffna. A descriptive cross-sectional study was carried out among service-users at the Motor Traffic Department, District Secretariat, Jaffna, between 12 noon and 4 pm during a six-week period. Data were collected through an interviewer-based questionnaire. Frequencies, proportions, and the Chi Square test were used to analyze the data with SPSS (v25). The critical level was set at 0.05. A total of 300 service users participated; of them, most were females (59%), between 18 to 39 years (77%), with at least O/L qualifications (90%). Knowledge on eligibility criteria for blood donation was low compared to knowledge on risk behaviors that rendered them ineligible. Although an overwhelming majority (96%) believed that people should donate blood, only 21% had donated once in their lifetime. The most common reason for not having donated blood was that they had not been approached for blood donation (42%). Male gender (p&lt;0.001) and being employed (p=0.013) were significantly associated with having donated blood. Knowledge gaps exist even among a fairly educated population in Jaffna. Attitudes on blood donation seem favourable, although practices are poor. Blood donation campaigns should address knowledge gaps and actively recruit the public for blood donation. Strategies should be developed to encourage voluntary blood donation.

PAPARAN KONSELING TERHADAP PENGETAHUAN DONOR DARAH PADA SISWA KELAS XI SMK NEGERI 1 JEPARA

School age is a productive age, an asset for the future, as a channel for promoting blood donation in the community, SMK Negeri 1 Jepara has never had any outreach activities about blood donation. It is the closest school to UDD PMI Jepara Regency. The results of interviews with PMR teachers at SMK Negeri 1 Jepara are known to have reported that on average students are afraid to donate blood, are afraid of needles, do not meet the criteria for blood donation, their blood will decrease or run out, do not know the benefits of donating blood, sell their blood, are afraid of contracting disease, become sick, there are systemic diseases and so on. This study aims to determine the exposure to blood donor counseling in class XI students of SMK Negeri 1 Jepara. This type of research is an analytic survey with a cross sectional design. The research population was all students of class XI SMK Negeri 1 Jepara. The sampling technique used purposive sampling as many as 84 students. The data includes regression analysis and coefficient of determination. The regression analysis test after being given blood donation counseling showed a significant effect on blood donor knowledge in students, P Value was 0.024 &lt; 0.05 (P Value &lt; 0.05). The conclusion obtained is that there is counseling exposure to blood donor knowledge in class XI students of SMK Negeri 1 Jepara.

Prevalence and risk factors of Hepatitis B virus infection among blood donors in Gabonese National Blood Transfusion Center: A cross-sectional and analytic study

Hepatitis B virus (HBV) infection is prevalent in Gabon and poses a potential risk of transmission by blood transfusion. However, few studies have examined epidemiological data regarding HBV infection of Gabonese blood donors. This article reports on research conducted to estimate the seroprevalence of HBV and associated risk factors in the urban population of Gabon. A cross-sectional and analytic study survey of blood donors attending at the Gabonese National Blood Transfusion Center, was carried out between June and August 2020. The ELISA technique (Evolis®, BioRad) and the chemiluminescence technique (Cobas® e601, Roche) had been used for the detection of hepatitis B surface antigens in the plasma of donors. Repeatedly reactive hepatitis B surface antigen levels among first-time and repeat donors were used to assess prevalence and risk factors using multivariable logistic regression. Results revealed that a total of 3665 donations were collected at the Gabonese National Blood Transfusion Center, of which 100 were con?rmed HBV positive. The seroprevalence of HBsAg among total blood donors was 5.5% (95% confidence interval [CI] = 4.4 - 6.7) indicating a moderate burden. In our multivariate analysis controlling for age, HBsAg positivity was associated with first-time donor status (aOR = 6.5) and residence outside of Libreville (aOR = 1). The prevalence of HBsAg among Gabonese blood donors is at a moderate-level endemicity among first-time donors, indicating the need to further limit the burden. In this Gabonese context, status of first-time blood donor and living in rural settings are primary risk factors of HBV-infection, and henceforth considered as exclusionary criteria for blood donation in Gabon. Key words: Hepatitis B, prevalence, risk factors, blood donor

Seropositive coronavirus disease 2019 detection among apparently healthy voluntary blood donors

Background Despite the prevailing pandemic of coronavirus disease 2019, there are no recommendations available yet for serological screening of apparently healthy asymptomatic blood donors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies. Objective To explore the seropositivity for SARS-CoV-2 antibodies in serum samples of a group of randomly selected Egyptian voluntary blood donors who met the eligibility criteria for blood donation as a preliminary step to catch apparently healthy asymptomatic participants who constitute an important source of viral spread in the community. Patients and methods The first phase of our study design plan included 100 anonymous serum samples of a group of voluntary blood donors who donated blood at Ain-Shams University Hospitals’ blood bank during the period from the second week of September to the end of October 2020. After completion of the steps of donation, donors’ stored serum samples were screened for SARS-CoV-2-specific immunoglobulin (Ig)M and IgG antibodies. The next phase of our study design plan is intended to include larger samples of known apparently healthy asymptomatic blood donors in an attempt to reach seropositive patients to confirm the results by PCR and validate the testing. Results A total of 100 anonymous serum samples were included in the study. Eleven (11%) samples were reactive for viral specific IgM antibodies, and 38 (38%) samples were reactive for viral specific IgG antibodies. Conclusion As the ongoing pandemic of coronavirus disease 2019 is continuing to demand urgent attention, screening of all asymptomatic apparently healthy voluntary blood donors for SARS-CoV-2 antibodies followed by viral RNA detection by PCR in seropositive donors could abort viral spread to others in blood centers and eventually to the rest of the community.

Screening of Occult Hepatitis B Virus Infection among Egyptian Blood Donors.

Background:Although sensitive screening assays for hepatitis B virus surface antigen (HBsAg) are available, special cases of post-transfusion hepatitis B virus infection still occur. The present study was conducted to evaluate the prevalence of anti-hepatitis B core (anti-HBc) positivity and the presence of HBV-DNA in serum samples of healthy blood donors negative for both HBsAg and anti-HCV antibodies in Benha, Egypt. Materials and methods: The study included a screening of 450 selected blood donors. The distribution of blood donors was 288 males (64%) and 162 females (36%). The recruited blood donors who met the criteria for blood donation were routinely screened for HBsAg, HIV I/2-Ab, and syphilis-antibodies. The blood units for donations were further analyzed for the presence of HBc-IgM and HBV-DNA levels by PCR method. Results: Testing of the accepted units for the donation was about 12 (2.7%) HBc-IgM positive, and 9 (2%) HBV-DNA positive units. The standard screening of blood unit failed to recognize early acute or window HBV infection where HBsAg is missing. Conclusions:Our investigations proposed that sensitive methods for the detection of HBV by PCR might be recommended in the screening of donated blood. Furthermore, anti-HBc antibodies should be tested regularly on all blood donation units.

Emerging infectious disease and transfusion-transmitted infection

Hepatitis B, hepatitis C and HIV infections are well-known infectious diseases caused by blood products, but recently there have been almost no reports. In 2011, hepatitis E virus (HEV) antibody test was covered by insurance in Japan, and certain numbers of transfusion-transmitted HEV were reported, and five cases were recognized in 2019. As the Japanese Red Cross has started to examine individual NAT of HEV for all blood donors since August 2020, and the number of transfusion-transmitted HEV will decrease. In addition, Trypanosoma cruzi antibody test for selective blood donors has been examined since August 2016, and the risk of Chagas disease infection by blood transfusion will be decreased. In the future, it is important for protecting against the transfusion-transmitted infection to inspect bacterial tests and know the information of emerging infectious disease occurring overseas. When the emerging infectious diseases such as DENV (dengue virus), WNV (West Nile virus), Zika (Zika virus) and CHIKV (chikungunya virus) occur in Japan, it is necessary to stimulate countermeasures and prepare what kind of tests should be performed for blood donors or criteria for blood donation.

Sexo entre homens e vulnerabilidade moral: percepções de estudantes de medicina sobre as restrições à doação de sangue

Objetivo: Investigar o conhecimento e opiniões de estudantes de medicina sobre os atuais critérios de doação de sangue, incluindo aqueles relacionados aos homens que fazem sexo com outros homens (HSH), analisando as implicações éticas e morais a partir da luz da bioética. Métodos: Trata-se de um estudo exploratório, descritivo, observacional e com abordagem quantitativa, desenvolvido com a participação de 167 estudantes do curso de medicina de uma universidade pública localizada em Belém/Pará. O questionário foi aplicado através da Plataforma Google Forms, após aprovação em Comitê de Ética em Pesquisa. Resultados: Constatou-se que a maioria dos participantes tinham conhecimento dos critérios de doação de sangue e das restrições aplicadas a HSH. Entretanto, mais de 80% dos participantes concordava que tal restrição era um indicativo da vulnerabilidade moral desses indivíduos, sendo que a maioria não se opunha a receber sangue doado por HSH. Conclusão: Em se tratando da educação médica, os resultados demonstram a importância de um maior debate sobre o tema na formação de futuros profissionais, de modo a problematizar os argumentos usados na adoção de tais critérios.

Terapia Con Plasma De Convaleciente Para Pacientes Con COVID-19: Revisión De La Literatura

The coronavirus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) infection has created a pandemic leading to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support. To date, there is no specific antivirus treatment for COVID-19. The use of convalescent plasma transfusions could be of great value in the current pandemic. Recently recovered SARS-CoV-2 patients who may be suitable donors undergo apheresis in order to obtain convalescent plasma containing high-titer antibodies, granted they meet blood donation criteria. In this review, we summarize existing literature around convalescent plasma as a therapeutic option for COVID-19. It is important to note that the appropriate timing on convalescent plasma administration and the severity of its adverse effects needs to be further studied. Convalescent plasma provides the potential to render an immediate promising treatment option while evaluating existing drugs and developing new specific vaccines and therapies.