Leiomyoma Of Bladder Research Articles

Ultrasound and Computed Tomography Findings of a Calcified Intramural Leiomyoma of Urinary Bladder in a Dog

Ultrasound and Computed Tomography Findings of a Calcified Intramural Leiomyoma of Urinary Bladder in a Dog

Leiomyoma of bladder: a clinical case

Leiomyoma of bladder: a clinical case

Bladder leiomyoma in a sheep: a rare case report

Bladder leiomyoma in a sheep: a rare case report

Laparoscopic Enucleation of an Extravesical Bladder Leiomyoma: A Case Report

BackgroundThe management of leiomyomas, the most common benign mesenchymal tumours, remains highly debated. This case report presents the first laparoscopic enucleation of an extravesical bladder leiomyoma in Indonesia.Case presentationA 48-year-old man presented with a lower abdominal mass. An abdominopelvic computed tomography scan showed a solid tumour mass in the right anterolateral wall of the bladder. To excise the mass, it was planned for the patient to undergo laparoscopic enucleation. The mass was removed intact, and a frozen section was taken to determine the malignancy profile. Histopathological examinations, followed by immunohistochemical examinations, confirmed the diagnosis of leiomyoma.ConclusionsLaparoscopic enucleation is a promising option for managing bladder masses. It is a minimally invasive procedure with optimal results for preserving bladder function. Prior to the surgery, imaging studies and cystoscopy examination are mandatory.

Recurrent bladder leiomyoma: a case report

BackgroundBladder leiomyomas are rare benign growths in the bladder, comprising less than 0.5% of bladder tumors with only 250 cases reported globally. They are more common in women. This case involves a 70-year-old woman with recurrent leiomyoma, presenting with lower urinary tract symptoms and painless hematuria. A recurrent bladder leiomyoma is rarely reported, making its presence exceptionally rare.Case presentationA 70-year-old Pakistani woman with hypertension and diabetes presented with lower urinary tract symptoms (LUTS) and painless hematuria. She had a history of similar symptoms in 2010, leading to a diagnosis of bladder leiomyoma via cystoscopy and biopsy. Imaging studies revealed a substantial 3.7 × 4 × 4.0 cm isodense mass with calcifications at the bladder base, along with bladder wall thickening and diverticula. Pathological examination during Transurethral Resection of Bladder Tumor (TURBT) confirmed the presence of bladder tissue with smooth muscle, ruling out malignancy. Immunohistochemical studies supported the diagnosis. A successful TURBT was performed, and the patient recovered well.DiscussionRecurrent bladder leiomyoma is a rarely-discussed topic in medical literature. This article primarily aims to review existing studies and present a detailed case study, shedding light on this rare phenomenon.

The Value of Amide Proton Transfer MRI in the Diagnosis of Malignant and Benign Urinary Bladder Lesions: Comparison With Diffusion-Weighted Imaging.

Conventional magnetic resonance imaging (MRI) has certain limitations in distinguishing between malignant and benign urinary bladder (UB) lesions. Amide proton transfer (APT) imaging may provide more diagnostic information than diffusion-weighted imaging (DWI) to distinguish between malignant and benign UB. To investigate the potential of APT imaging in the diagnosis of malignant and benign UB lesions and to compare its diagnostic efficacy with that of conventional DWI. Prospective. Eighty patients with UB lesions. A 3.0 T/turbo spin echo (TSE) T1-weighted and T2-weighted imaging, single-shot echo planar DWI, and three-dimensional TSE APT imaging. Patients underwent radical cystectomy or transurethral resection of the bladder lesions within 2 weeks after CT urography and MRI examination. APT signal intensity in UB lesions was quantified by the asymmetric magnetization transfer ratio (MTRasym). MTRasym and apparent diffusion coefficient (ADC) values were measured and compared between malignant and benign UB lesions. Kolmogorov-Smirnov test, Student's t test or Mann-Whitney U test, Spearman rank correlation coefficient, area under the receiver operating characteristic (ROC) curve (AUC), Delong test, and intraclass correlation coefficient (ICC). The significance threshold was set at P < 0.05. Thirty-two patients had pathologically confirmed benign UB lesions, including 2 bladder leiomyomas, 1 submucosal amyloidosis, 1 inflammatory myofibroblastic tumor, and 28 inflammatory lesions, and 48 patients had pathologically confirmed urothelial carcinoma. Urothelial carcinomas showed significantly higher MTRasym values (1.53% [0.74%] vs. 0.85% [0.23%]) and significantly lower ADC values (1.24 ± 0.34 × 10-3 mm2/s vs. 1.43 ± 0.22 × 10-3 mm2/s) than benign UB lesions. The MTRasym value (AUC = 0.928) was significantly better in differentiating urothelial carcinoma from benign UB lesions than the ADC value (AUC = 0.722). APT imaging may have value in discriminating malignant from benign UB lesions and has better diagnostic performance than DWI. 3 TECHNICAL EFFICACY: Stage 2.

Robotic assisted transvesical excision of recurrent bladder leiomyoma with intraoperative ultrasound guidance

Leiomyoma of the urinary bladder is uncommon benign tumor with a wide range of clinical presentations. Surgical excision remains the definitive treatment of leiomyoma with excellent outcomes. Seldom literatures reported the use of robotic-assisted surgical techniques for its excision. A 51-year-old woman presented with frequent episodes of visible hematuria in consistence with lower urinary tract symptoms. The initial diagnosis was a urinary tract infection. However, symptoms did not resolve even with the proper antibiotics. After further investigations a soft tissue density mass measuring 20 × 23 × 20 mm within the left posterior wall of the urinary bladder extending towards the bladder neck was found. The histological finding of the transurethral resected biopsy of the mass revealed a benign submucosal leiomyoma of the bladder with no evidence of any malignancy. Using the Intuitive Da Vinci X system the tumor was excised using the ultrasound guidance to define the tumour margins, sparing the left ureteric orifice and ureter. The patient was discharged home on the day of surgery, with a urethral catheter in place. The catheter was successfully removed after 10 days, with cystogram prior confirming no leakage. The ureteric stent was removed by flexible cystoscopy two weeks later. The final histology was reported as a bladder leiomyoma with no evidence of malignant features and negative circumferential resection margins. Herein, in the current case we present a safe and effective technique for the excision of recurrent bladder leiomyoma using the robotic-assisted transvesical approach with intraoperative ultrasound guidance.

V03-04 FIRST HUMAN NOTES FOR BLADDER LEIOMYOMA ENUCLEATION AND CYSTORRAPHY

You have accessJournal of UrologyCME1 Apr 2023V03-04 FIRST HUMAN NOTES FOR BLADDER LEIOMYOMA ENUCLEATION AND CYSTORRAPHY Andreia Cardoso, Sara Anacleto, Catarina Laranjo Tinoco, Ricardo Matos Rodrigues, Ana Sofia Araújo, Mariana Capinha, Vera Marques, João Pimentel Torres, Carlos Oliveira, Miguel Mendes, and Emanuel Carvalho-Dias Andreia CardosoAndreia Cardoso More articles by this author , Sara AnacletoSara Anacleto More articles by this author , Catarina Laranjo TinocoCatarina Laranjo Tinoco More articles by this author , Ricardo Matos RodriguesRicardo Matos Rodrigues More articles by this author , Ana Sofia AraújoAna Sofia Araújo More articles by this author , Mariana CapinhaMariana Capinha More articles by this author , Vera MarquesVera Marques More articles by this author , João Pimentel TorresJoão Pimentel Torres More articles by this author , Carlos OliveiraCarlos Oliveira More articles by this author , Miguel MendesMiguel Mendes More articles by this author , and Emanuel Carvalho-DiasEmanuel Carvalho-Dias More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003241.04AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Bladder leiomyomas (BL) are rare benign tumors, with roughly 250 cases reported worldwide. Surgical excision is the recommended treatment, classically through open partial cystectomy. As alternatives, minimally invasive approaches, such as laparoscopic (lap), robot-assisted and transurethral (TU) resection (TUR), are arising. In parallel, TU cystorraphy has been reported for vesicovaginal fistulas or traumatic perforations. Thus, to the best of our knowledge, we report the 1st Human Natural Orifice Transluminal Endoscopic Surgery (NOTES) with a purely TU approach for BL enucleation and cystorraphy, without transvesical access, gas insufflation, neither extracorporeal knot tying. METHODS: A 68-year-old woman presented an incidental 22mm lesion on the left posterolateral bladder wall on MRI, highly suspicious for BL. After cystocopic confirmation of a submucosal lesion, TUR was proposed. We performed a pioneer NOTES with total TU BL enucleation and cystorraphy using: 30° lens, white light only, saline irrigation, 26Ch resectoscope, operative cystoscope, Collin’s knife and standard resection loop, bipolar energy, 5mm lap needle holder and 3-0 V-Loc 23cm length suture. RESULTS: BL complete enucleation was done with bipolar energy on Collin’s knife and standard resection loop. Then, V-Loc suture was completely placed inside the bladder through the operative cystoscope, and with the lap needle holder inserted through it, a total intravesical cystorraphy with single hand continuous suture was performed. Operative time was 40min. Patient was discharged on the next day, with bladder catheter for 5 days. There were no complications. CONCLUSIONS: TUR has been used for BL, but without cystorraphy, which is a limitation for bigger or more profound infiltrative lesions. Cystorraphy techniques combining TU, transperitoneal and/or transmural bladder access were reported. A purely TU cystorraphy recently reported required extracorporeal sliding knot techniques, so, it was only possible in women. Thus, our approach may be the most minimally invasive possible for the safest treatment of BL. We combined several techniques aiming to reach an ideal one. Using only regular material, a single urethral route, and no gas insufflation, we achieved a quick and safe procedure, with no need for continuous bladder irrigation and short catheterization. Yet, it requires advanced skills such as single hand lap suturing. Our technique seems also feasible in small bladder perforations, fistulas, or other lesions (e.g.: endometriosis). Additionally, with total intravesical suture, it may also be viable in men. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e247 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Andreia Cardoso More articles by this author Sara Anacleto More articles by this author Catarina Laranjo Tinoco More articles by this author Ricardo Matos Rodrigues More articles by this author Ana Sofia Araújo More articles by this author Mariana Capinha More articles by this author Vera Marques More articles by this author João Pimentel Torres More articles by this author Carlos Oliveira More articles by this author Miguel Mendes More articles by this author Emanuel Carvalho-Dias More articles by this author Expand All Advertisement PDF downloadLoading ...

First human NOTES for bladder leiomyoma enucleation and cystorraphy

First human NOTES for bladder leiomyoma enucleation and cystorraphy

Minimally invasive treatment of bladder leiomyoma: Endoscopic and laparoscopic approaches

Minimally invasive treatment of bladder leiomyoma: Endoscopic and laparoscopic approaches

Urinary Bladder Leiomyoma Causing Obstructive Uropathy: A Case Report and Literature Review

This is the first time a large endovesical leiomyoma of the urinary bladder has been reported in India. A 44-year-old woman had painless gross haematuria, increased urine frequency, an incomplete emptying feeling, and left loin discomfort. Imaging and cystoscopy revealed a 6 x 5 cm projecting endovesical tumour emerging from the bladder's base near the left vesico-ureteric junction. Transurethral bladder resection with few biopsies was performed, histopathological examination revealed a pathological diagnosis of a leiomyoma of the urinary bladder. Intravesical complete excision of the tumor was performed after ligating its pedicle. Complete surgical resection is a very effective treatment, associated with almost no recurrence. We discuss the relevant recent literature of bladder leiomyoma.

Quantitative MRI in distinguishing bladder paraganglioma from bladder leiomyoma.

To investigate the feasibility of quantitative MRI in the differentiation of bladder paraganglioma from bladder leiomyoma. From 2014 to 2021, 11 patients with bladder paraganglioma and 14 patients with bladder leiomyoma confirmed by surgical pathology were retrospectively collected. All patients underwent multiparametric scanning with a 3.0T MR system. Quantitative parameters including the SI-ratio on T1WI between the solid component of tumours and piriformis, ADC value and E-rate of the solid component of tumours were assessed. Independent sample t test or Mann-Whitney U test was used to compare these parameters between the two groups. The diagnostic efficiency of the parameters was examined using ROC curve analysis and the DeLong test. There were significant differences in SI-ratio on T1WI (P < 0.001), ADC value (P = 0.002) and the E-rate (P = 0.040) between the paraganglioma group and the leiomyoma group. The cutoff value of SI-ratio on 3 leiomyoma was 1.241, and the AUC was 1.000 (0.858-1.000). The cutoff value of the ADC value was 0.979 × 10-3mm2/s, and the AUC was 0.907 (0.717-0.987). The cutoff value of E-rate was 98.7%, and the AUC was 0.714 (0.495-0.878). The AUCs of the SI-ratio on T1WI and ADC value were significantly higher than the E-rate AUC (P = 0.015 and 0.034, respectively). Quantitative MRI can effectively distinguish bladder paraganglioma from bladder leiomyoma with the SI-ratio on T1WI or ADC value.

Редкий случай лейомиомы мочевого пузыря во время беременности: клиническое наблюдение

We present a rare case of leiomyoma of the urinary bladder that was diagnosed during pregnancy. The case of a 29-year-old woman primigravida at 13 weeks of pregnancy who presented with 6 months history of abdominal swelling which was gradually increasing in size. Computed tomography done revealed a large heterogenous mass(enhancing) with an area of non-enhancing (necrosis) suggestive of malignant ovarian tumor. The histological findings of the surgical specimen confirmed a leiomyoma of the urinary bladder. The clinical presentation, imaging findings, and management of this relatively rare benign tumor are discussed in this case report.

Asymptomatic bladder leiomyoma: a report of three cases treated with minimal invasive techniques and a review of literature

Introduction: Bladder leiomyoma is a very rare neoplasm and are estimated at about &lt; 0.5% of all urinary bladder tumors. Most patients complain of lower urinary track symptoms. In 20% of cases patients remain asymptomatic.&#x0D; Objective: The aim of this study was to investigate the topic of bladder leiomyomas, present our experience in the management of this neoplasm and review the published data concerning this rare entity.&#x0D; Material and methods: From March 2018 to February 2021 three patients (2 females, 1 male) aged 39 to 58 years (mean 49.3 years) were treated for bladder leiomyoma in our center.&#x0D; Results: Two patients underwent en bloc transurethral resection of bladder tumor and one had laparoscopic partial cystectomy. Tumors were located in favourable positions with the mean diameter of 37.67 mm. The mean operative time was 46.67 min (range from 15 to 95 min). At the mean follow-up time of 36 months. None of our patients had a recurrence of bladder leiomyoma.&#x0D; Conclusions: Properly performed removal of bladder leiomyoma gives satisfactory results. Transurethral resection of bladder tumor is the gold standard of treatment, highly valued for its safety and minimal invasiveness, however in cases of unfavourable located or large tumors laparoscopic approach or EBRT with defragmentation or morcellation may be preferred.

Case series - Prioritizing bladder-sparing treatments in patients with urinary tract leiomyoma: A report of three cases and updated literature review.

Urinary tract leiomyomas are rare, benign mesenchymal tumors that are traditionally treated with complete surgical excision. We present three cases of urinary tract leiomyoma - two located in the bladder and one in the ureter. Both bladder leiomyomas were treated with transurethral resection of bladder tumor (TURBT) with no evidence of recurrent disease, while the upper tract leiomyoma was managed with surveillance by patient preference, which to our knowledge, has not been previously described. The ureteral leiomyoma has remained stable at five years followup from initial diagnosis. Given the benign nature of leiomyomas and the overall low recurrence rate reported in the literature, bladder-sparing options should be emphasized when feasible, with active surveillance potentially applicable for highly select patients.

V09-02 THULIUM FIBER LASER FOR BLADDER LEIOMYOMA TREATMENT

You have accessJournal of UrologyCME1 May 2022V09-02 THULIUM FIBER LASER FOR BLADDER LEIOMYOMA TREATMENT Alim Dymov, Evgeny Shpot, Alexandra Proskura, Roman Sukhanov, Vladimir Lekarev, Temirlan Karakotov, Yuliya Lee, and Leonid Rapoport Alim DymovAlim Dymov More articles by this author , Evgeny ShpotEvgeny Shpot More articles by this author , Alexandra ProskuraAlexandra Proskura More articles by this author , Roman SukhanovRoman Sukhanov More articles by this author , Vladimir LekarevVladimir Lekarev More articles by this author , Temirlan KarakotovTemirlan Karakotov More articles by this author , Yuliya LeeYuliya Lee More articles by this author , and Leonid RapoportLeonid Rapoport More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002617.02AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Bladder leiomyomas are very rare, representing only 0.43% of all bladder tumors. Today the most common surgical treatment options for bladder leiomyoma are transurethral, open, laparoscopic and robotic resection. Due to very low incidence rate the assessment of efficacy and safety of different surgical techniques is yet to be done. We present a series of 6 cases of bladder leiomyoma treated with Thulium Fiber laser (TFL) en bloc resection. This report aims to investigate the feasibility, safety and efficacy of TFL en bloc resection for the treatment of bladder leiomyoma and to present our surgical technique. METHODS: From January 2019 up to present time 6 female patients with bladder leiomyoma (size 1.5 cm - 4.0 cm) underwent TFL en bloc resection. All surgeries were performed with regular laser resectoscope (Richard Wolf GmbH, Knittlingen, Germany; Karl Storz, Tuttlingen, Germany), 600 μm laser fiber and TFL («FiberLase» IRE-Polus, Russia) operating at wavelength 1.94 µm. Laser settings - 1 J, 10 Hz, 10 W. Two out of six resected tumors were morcellated, three were removed with a bipolar loop, and one 2 cm tumor was extracted with Allis clamp. Intra- and postoperative complications were evaluated. RESULTS: All tumors were resected as a whole. Mean operative time was 24 min (10 - 40 min). Mean catheter time was 28 hours (24 - 48 hrs), mean length of hospital stay was 76 hours (72 - 96 hrs). No bladder perforation, obturator nerve stimulation, significant bleeding and postoperative complications were recorded. Morphological examination of resected tissues confirmed leiomyoma. CONCLUSIONS: Based on our experience TFL en bloc resection is an effective and safe option for the surgical treatment of bladder leiomyoma. Moreover, it seems to provide fast recovery from the surgery. Source of Funding: None © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e805 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alim Dymov More articles by this author Evgeny Shpot More articles by this author Alexandra Proskura More articles by this author Roman Sukhanov More articles by this author Vladimir Lekarev More articles by this author Temirlan Karakotov More articles by this author Yuliya Lee More articles by this author Leonid Rapoport More articles by this author Expand All Advertisement PDF DownloadLoading ...

HF02-14 HERMAN KRETSCHMER: FROM GENITOURINARY PATHOLOGY TO PRESIDENCY

You have accessJournal of UrologyCME1 May 2022HF02-14 HERMAN KRETSCHMER: FROM GENITOURINARY PATHOLOGY TO PRESIDENCY Alice Cheung Alice CheungAlice Cheung More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002540.14AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Herman Kretschmer (1879-1951) was a urologist who made significant contributions to genitourinary pathology and academic urology. METHODS: A thorough literature review was performed. RESULTS: Herman Kretschmer was born in Chicago, where he grew up and later graduated from the Northwestern University School of Pharmacy in 1900. He continued his studies at Northwestern University Medical School where he graduated magna cum laude in 1904. After graduation, he completed an internship at Alexian Brothers Hospital before traveling abroad to Vienna to study under Otto Zuckerkandl from 1906 to 1907. Kretschmer studied “essential hematuria” while in Vienna, and his work was eventually published in the first volume of the Zeitschrift for Urologie. Kretschmer made many contributions to pathology in the genitourinary tract and firmly believed that every urologist should be a close student of pathology. He had over 285 scientific publications under his name, many with a focus on genitourinary pathology. His publications included work on bladder leiomyoma, prostate cancer and diethylstilbestrol, acute and chronic epididymitis, and prostatic sarcoma. A strong dedication to academic medicine led Kretschmer to serve in a wide variety of academic societies, including holding the titles of Chairman of the Section of Urology of the American Medical Association, President of the American Board of Urology, and President of the American Urological Association. He earned himself several awards and honors throughout his career, while also finding time to give back to his community. The preservation of the Pasteur monument in Convalescent Park in Chicago was due in part to Kretschmer’s philanthropic efforts. He passed away in his Chicago home on September 23, 1951 and was commemorated fondly in an obituary published in JAMA. CONCLUSIONS: Herman Kretschmer devoted his life to the study of genitourinary pathology and was the exemplification of an interdisciplinary academic physician. His involvement and participation in academic urology helped shape the urologic societies present today. Source of Funding: none © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e210 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alice Cheung More articles by this author Expand All Advertisement PDF DownloadLoading ...

V14 - Thulium fiber laser for bladder leiomyoma treatment

V14 - Thulium fiber laser for bladder leiomyoma treatment

Computed tomographic appearance of bladder and vaginal leiomyoma in dog: case report

Computed tomographic appearance of bladder and vaginal leiomyoma in dog: case report

Giant leiomyoma of the urinary bladder: A case report

Urinary bladder leiomyoma is a rare tumour accounting for less than 0.5% of all urinary bladder tumours. Till now, less than 250 cases were documented with variable sizes, most of them were less than 10 cm in maximum diameter. Here we present a 68- year-old female patient with urinary bladder giant leiomyoma measuring about 13 cm. She presented with right loin pain. Postcontrast computed tomography of the abdomen and pelvis revealed a large posterolateral right-sided urinary bladder mass with moderate right hydroureteronephrosis. It was managed by partial cystectomy. The patient had an uneventful postoperative course. Postoperative pathological examination of the specimen confirmed giant leiomyoma of the urinary bladder.