The need for effective hair loss treatments has fostered research and the emergence of several biotechnology companies. Pharmacological approaches, although competitive, have been surpassed by cell-based therapies, which remain clinically immature. B... Read More
Biotechnology Research Articles
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6455 Articles
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The booming business of hair loss
- Trends in Biotechnology
- VOL. 41
on Jun 1, 2023
- Biotechnology Companies
- Hair Loss
- Additional Strategies
- Pharmacological Approaches
- Cell-based Therapies
- Need For Treatments
- More +
Metabolomics of infectious diseases in the era of personalized medicine
- Frontiers in Molecular Biosciences
- VOL. 10
on May 18, 2023
- Diagnosis Of Infectious Diseases
- Differential Treatment Response
- FDA
- Proteomic Information
- Omics Technology
- Diagnostics Kits
- More +
Infectious diseases continue to be a major cause of morbidity and mortality worldwide. Diseases cause perturbation of the host’s immune system provoking a response that involves genes, proteins and metabolites. While genes are regulated by epigenetic... Read More
Despotic Leadership and Ideological Manipulation at Theranos: Towards a theory of hegemonic totalism in the workplace
- Organization Studies
on May 18, 2023
- Biotech Company
- Ideological Manipulation
- Despotic Leadership
- Healthcare Diagnostics
- Business Leaders
- High Silicon
- More +
This paper addresses despotic leadership and ideological manipulation in the workplace, and explores their detrimental consequences for employees and other stakeholders. The notion of ‘hegemonic totalism’ is advanced to account for how employees are... Read More
The Effects of Fractional Relaxation Time and Magnetic Field on Blood Flow through Arteries along with Nanoparticles
- Defect and Diffusion Forum
- VOL. 424
on May 8, 2023
- Magnetic Particles
- Relaxation Time Parameter
- Application Of External Magnetic Field
- Relaxation Time
- Fractional Partial Differential Equation
- Blood Flow
- More +
In this paper, we report the effects of fractional relaxation time on the parameters of blood flow together with magnetic particles through straight circular cylindrical arterial segment. A mathematical model of blood flow subject to pulsatile pressu... Read More
Targeting the biology of aging with mTOR inhibitors
- Nature Aging
on May 4, 2023
- Biotechnology Companies
- Mouse Models Of Human Diseases
- Diverse Model Organisms
- Kinase Mechanistic Target Of Rapamycin
- mTOR Inhibitors
- FDA
- More +
Inhibition of the protein kinase mechanistic target of rapamycin (mTOR) with the Food and Drug Administration (FDA)-approved therapeutic rapamycin promotes health and longevity in diverse model organisms. More recently, specific inhibition of mTORC1 ... Read More
Technical considerations for the implementation of the Multi-Attribute-Method by mass spectrometry in a Quality Control laboratory
- European Journal of Pharmaceutics and Biopharmaceutics
on May 1, 2023
- QC Laboratory
- EFPIA
- GMP Compliance
- Quality Expert Group
- Technical Considerations
- GMP
- More +
Multi-attribute methods employing mass spectrometry are applied throughout the biopharmaceutical industry for product and process characterization purposes but are not yet widely accepted as a method for batch release and stability testing under good... Read More
Strategy for Pre-Clinical Development of Active Targeting MicroRNA Oligonucleotide Therapeutics for Unmet Medical Needs
- International Journal of Molecular Sciences
- VOL. 24
on Apr 12, 2023
- Biotechnology Company
- Unmet Medical Needs
- MAFLD
- Centers Of Excellence
- Active Targeting
- Academic Institutions
- More +
We present here an innovative modular and outsourced model of drug research and development for microRNA oligonucleotide therapeutics (miRNA ONTs). This model is being implemented by a biotechnology company, namely AptamiR Therapeutics, in collaborat... Read More
In the business of base editors: Evolution from bench to bedside
- PLOS Biology
- VOL. 21
on Apr 12, 2023
- Startup Biotechnology Companies
- Academic Labs
- Base Editing
- Gene Editing
- Point Mutations
- Clinical Trials
- More +
With the advent of recombinant DNA technology in the 1970s, the idea of using gene therapies to treat human genetic diseases captured the interest and imagination of scientists around the world. Years later, enabled largely by the development of CRIS... Read More
Scaled-Up Preparation of an Intermediate of Upatinib, ACT051-3
- Journal of Visualized Experiments
on Apr 7, 2023
- Pilot Scale-up
- Industrial Production
- Development Of Industrial Process
- Tert-butyl Carbamate
- Optimal Production Process
- Development Of Production Process
- More +
Upatinib, a Janus kinase inhibitor drug, was developed by a biotech company to treat immune diseases. The compound tert-butyl (5-toluenesulfonyl-5h-pyrrole [2,3-b] pyrazine-2-yl) carbamate (ACT051-3) is an important intermediate of Upatinib. To date,... Read More
Abstract 5201: TNFR2 humanized mice: an ideal model for studying anti-TNFR2 antibodies
- Cancer Research
- VOL. 83
on Apr 4, 2023
- TNFR2
- anti-TNFR2 Antibodies
- Murine Transmembrane
- Treg Cells
- Tumor-infiltrating Tregs
- PD-L1 Therapies
- More +
Abstract Tumor necrosis factor (TNF) receptor 2 (TNFR2) is mainly expressed on the surface of regulatory T cells (Tregs) and CD8+ T cells, which can stimulate the proliferation of these cells through NF-kB activation. TNFR2 is also hig... Read More
Abstract 4563: Measuring immunotherapy responses ex vivo using novel 3D culture platform: E-slice
- Cancer Research
- VOL. 83
on Apr 4, 2023
- Immunotherapy Responses
- 3D Culture Platform
- Fresh Tumor Tissues
- Major Pharmaceutical Companies
- Clinical Deployment
- 3D Platform
- More +
Abstract Immunotherapies have provided dramatic and life-saving results in some patients; however, their effectiveness varies greatly in different tumors, even among patients with the same clinical diagnosis. Clearly, a better system t... Read More
Abstract 6129: The proapoptotic peptide PEP-010 is efficient on several models of different tumor origins and it can be monitored by pharmacodynamic biomarker candidates in clinical practice
- Cancer Research
- VOL. 83
on Apr 4, 2023
- Tumor Origins
- Models Of Origins
- Proapoptotic Proteins Caspase-9
- PP2A Interaction
- Proapoptotic Peptide
- Anti-cancer Peptide
- More +
Abstract In cancer cells, the proapoptotic proteins caspase-9 and PP2A interaction prevents them to play their role in apoptosis. PEP-010, a drug candidate developed by PEP-Therapy, a French Biotech company, is a proapoptotic peptide t... Read More
Recent progress in the synthesis of advanced biofuel and bioproducts
- Current Opinion in Biotechnology
- VOL. 80
on Apr 1, 2023
- Design Of Metabolic Engineering Strategies
- Face Of Global Climate Change
- Biofuels In Engines
- Liquid Transportation Fuels
- Combustion Of Fossil Fuels
- Chemical Building Blocks
- More +
Energy is one of the most complex fields of study and an issue that influences nearly every aspect of modern life. Over the past century, combustion of fossil fuels, particularly in the transportation sector, has been the dominant form of energy rele... Read More
Convergence of (Bio)technology and Psychiatry
- Journal of Affective Disorders Reports
- VOL. 12
on Apr 1, 2023
- Biotechnology
- Convergence Of Technology
Comparing the economic terms of biotechnology licenses from academic institutions with those between commercial firms
- PLOS ONE
- VOL. 18
on Mar 31, 2023
- Commercial Firms
- Early Investor
- Academic Institutions
- Academic Licenses
- Royalty Rate
- Substantive Effect
- More +
Licenses of drug-related biotechnologies from academic institutions to commercial firms are intended to promote practical applications of public sector research and a return on government investments in biomedical science. This empirical study compar... Read More
Sensitivity of eucalyptus (Eucalyptus urograndis) plants to subdoses of the herbicide dicamba
- Revista de Ciências Agroveterinárias
- VOL. 22
on Mar 28, 2023
- Biotechnology Companies
- Ae Ha-1
- Herbicide-resistant Weeds
- Cotton Cultivars
- Periods Of Evaluation
- Number Of Branches
- More +
In view of the widespread increase in herbicide-resistant weeds, biotechnology companies have developed dicamba-tolerant soybean and cotton cultivars. This technology can, however, increase the risk of the product drifting to adjacent areas. This stu... Read More
Empirical Study on Event Study Model on Biotech Stock Market
- Journal of World Science
- VOL. 2
on Mar 24, 2023
- Biotech Company
- Semi-strong Form Of Market Efficiency
- NASDAQ Stock Market
- Event Study Model
- Capital Market's Reaction
- COVID-19 Pandemic
- More +
Introduction: This study aims to determine and analyze the capital market's reaction to the Covid 19 Pandemic in biotechnology companies listed on the Nasdaq. Method: The method used in this study uses a type of quantitative method. This study uses a... Read More
ARTIFICIAL INTELLIGENCE IN METABOLOMIC RESEARCH
- International Journal of Health Management and Tourism
on Mar 10, 2023
- Biotechnology Companies
- Field Of Biotechnology
- Smart Data
- Development Of Innovations
- Machine Learning Techniques
- Vantage Point
- More +
The term "metabolomics" refers to high-throughput methods for detecting various metabolites and small molecules in biological samples. Undirected metabolomics, also known as unbiased global metabolome analysis, can be used to discover key metabolites... Read More
A low-cost smartphone fluorescence microscope for research, life science education, and STEM outreach
- Scientific Reports
- VOL. 13
on Mar 9, 2023
- Biotechnology Companies
- Hands-on Learning Activities
- Life Science Education
- US Dollars
- Fluorescence Microscopes
- STEM Outreach
- More +
Much of our understanding of cell and tissue development, structure, and function stems from fluorescence microscopy. The acquisition of colorful and glowing images engages and excites users ranging from seasoned microscopists to STEM students. Fluor... Read More
Application of Embedded Voice And Digital Forensics System In Financial Cost Management In Biotech Companies.
- Journal of Commercial Biotechnology
- VOL. 27
on Feb 15, 2023
- Biotech Companies
- Financial Cost Management
- Analysis Of Financial Transactions
- Enhance Data Security
- Voice Systems
- Financial Management
- More +
Financial cost management is a critical component of business operations in the biotech industry. Embedded voice and digital forensics systems are emerging technologies that can improve the efficiency and effectiveness of financial cost management. T... Read More