Bioactive Restorative Materials Research Articles

Evaluation of the microleakage of new bioactive restorative materials: a comparative in-vitro study.

This in-vitro study aimes to compare the microleakage of different restorative materials namely EQUIA Forte (GC, Japan), Tetric Evoceram (Ivoclar Vivadent, Liechtenstein), and Activa BioACTIVE. A standardized class V cavity has been created on the buccal surface of 40 sound premolar teeth. The cavity had the following measurements: 3 mm buccolingual height, 2 mm axial depth, and 4 mm mesiodistal width. The gingival margin was 1mm below the cementoenamel junction, whereas the coronal margin was on the enamel with cavosurface margins were butt joints all around. Four groups of teeth were restored according to the restorative materials. Under a stereomicroscope, the dye penetration test was used to measure the microleakage after thermocycling of the teeth. Data were compared using Kruskal-Wallis H and Mann-Whitney U tests. Occlusal and gingival margins did not show statistically significant differences among the four groups, but an intragroup analysis revealed a significant difference. The type of restorative material did not appear to have a substantial impact on microleakage, according to the findings of the current investigation.

Color Stability of Bioactive Restorative Material vs Nanohybrid Resin Composite: An In Vitro Study.

This study aimed to assess the color stability of bioactive restorative materials vs nanohybrid resin composites after 3 months of immersion in three frequently consumed beverages. Thirty disk-shaped specimens of Giomer dental restorative material (Shofu, Japan) and nanohybrid resin composite (Tokuyama, Japan) were performed using a Teflon mold. Super-Snap system (Shofu, Japan) was utilized to finish and polish the specimens to be preserved for 24 hours in distilled water at 37°C. The samples had been divided into three subgroups (Coffee, tea, Pepsi) (n = 5). The initially displayed color measurements of the samples were performed using a spectrophotometer (VITA Easyshade® V). After 7 days, 30 days, and 90 days, color measurements were repeated, and the E of each sample was estimated. E of each sample was calculated. The Giomer group showed statistically significant higher E values than the nanohybrid resin composite where the p-value was ≤0.0001. Tea subgroup showed the highest statistically significant E values in both groups where the p-value was ≤ 0.0001. The highest statistically significant color change was recorded at 3 months. The color of bioactive restorative material is less stable if compared with nanohybrid resin composite. As tea and coffee are popular beverages, particularly in Middle Eastern nations, dentists must advise patients about the color change of resin restorations. Patients are advised to brush their teeth immediately after consuming these beverages. How to cite this article: Saber EH, Abielhassan MH, Abed YA, et al. Color Stability of Bioactive Restorative Material vs Nanohybrid Resin Composite: An In Vitro Study. J Contemp Dent Pract 2024;25(3):221-225.

Effect of radiotherapy on the surface roughness and microhardness of contemporary bioactive restorative materials.

The aim of this in vitro study was to evaluate the effect of radiotherapy on the surface microhardness and roughness of different bioactive restorative materials. A total of 60-disc specimens (5mm × 2mm) were performed in four groups (n = 15 each) from Equia Forte HT, Cention N, Activa Bioactive Restorative, and Beautifil II. Following the polishing procedure (600, 1000, 1200 grit silicon carbide papers), all specimens were irradiated at 2Gy per fraction, five times a week for a total dose of 70Gy in 30 fractions over 7weeks. Before and after the irradiation, the specimens were analyzed regarding the surface roughness and microhardness. Surface morphology was also analyzed by scanning electron microscopy. Kruskal-Wallis test, Wilcoxon test, and paired sample t-test were used for statistical analysis. Significant differences were found after radiation with increased mean roughness of both Cention N (p = 0.001) and Beautifil II (p < 0.001) groups. In terms of microhardness, only the Beautifil II group showed significant differences with decreased values after radiation. There were statistically significant differences among the groups' roughness and microhardness data before and after radiotherapy (p < 0.05). The effect of radiotherapy might differ according to the type of the restorative material. Although results may differ for other tested materials, giomer tends to exhibit worse behaviour in terms of both surface roughness and microhardness. In patients undergoing head and neck radiotherapy, it should be taken into consideration that the treatment process may also have negative effects on the surface properties of anti-caries restorative materials.

The demineralization resistance and mechanical assessments of different bioactive restorative materials for primary and permanent teeth: an in vitro study

ObjectivesThis article examines the efficacy of two bioactive dental composites in preventing demineralization while preserving their mechanical and physical properties.Materials and methodsThe study compares Beautifil Kids and Predicta® Bioactive Bulk-Fill (Predicta) composites with conventional dental composite. Flexural strength and elastic modulus were evaluated using a universal testing machine. A pH-cycling model assessed the composites’ ability to prevent dentin demineralization. Color stability and surface roughness were measured using a spectrophotometer and non-contact profilometer, respectively, before and after pH-cycling, brushing simulation, and thermocycling aging.ResultsBeautifil Kids exhibited the highest flexural strength and elastic modulus among the materials (p < 0.05). Predicta demonstrated the highest increase in dentin surface microhardness following the pH-cycling model (p < 0.05). All groups showed clinically significant color changes after pH-cycling, with no significant differences between them (p > 0.05). Predicta exhibited greater color change after brushing and increased surface roughness after thermocycling aging (p < 0.05). While Beautifil Kids had higher surface roughness after pH-cycling (p < 0.05).Discussion/ConclusionBioactive restorative materials with ion-releasing properties demonstrate excellent resistance to demineralization while maintaining mechanical and physical properties comparable to the control group.

Shear bond strength of calcium silicate-based cements to glass ionomers

BackgroundA shear bond strength between the biomaterial and restorative material is crucial for minimizing bacterial microleakage and ensuring a favorable long-term prognosis for vital pulp therapy. This study aimed to conduct a comparative evaluation of the shear bond strength between calcium silicate-based biomaterials utilized in vital pulp treatment and various glass ionomer cement materials, both with and without the application of adhesive agents.MethodsA total of 270 acrylic blocks, each featuring cavities measuring 4 mm in diameter and 2 mm in depth, were prepared. Calcium silicate-containing biomaterials (ProRoot MTA, Medcem Pure Portland Cement, and Medcem MTA), following manufacturers’ instructions, were placed within the voids in the acrylic blocks and allowed to set for the recommended durations. The biomaterial samples were randomly categorized into three groups based on the restorative material to be applied: conventional glass ionomer cement, resin-modified glass ionomer cement, and bioactive restorative material. Using cylindrical molds with a diameter of 3.2 mm and a height of 3 mm, restorative materials were applied to the biomaterials in two different methods, contingent on whether adhesive was administered. After all samples were incubated in an oven at 37 °C for 24 h, shear bond strength values were measured utilizing a universal testing device. The obtained data were statistically evaluated using ANOVA and post-hoc Tukey tests.ResultsThe highest shear bond strength value was noted in the Medcem MTA + ACTIVA bioactive restorative material group with adhesive application, while the lowest shear bond strength value was observed in the ProRoot MTA White + Equia Forte HT Fil group without adhesive application (P < 0.05).ConclusionActiva Bioactive Restorative may be considered a suitable restorative material in combination with calcium silicate-based biomaterials for vital pulp treatment. The application of adhesives to calcium silicate-based biomaterials can effectively address the technical limitations.

In vitro remineralization of adjacent interproximal enamel carious lesions in primary molars using a bioactive bulk-fill composite

BackgroundSurface remineralization is recommended for the management of active non-cavitated interproximal carious lesions in primary teeth. According to the American Academy of Pediatric Dentistry, a recently recognized category of materials called bioactive restorative materials can be used for remineralization. This study aimed to evaluate the release of fluoride (F), calcium (Ca) and phosphate (P) ions from Predicta® Bioactive Bulk-fill composite compared with EQUIA Forte® and Filtek™ Z350 and to determine the remineralization effect of these 3 restorative materials on adjacent initial interproximal enamel carious lesions.MethodsThe release of F, Ca and P ions from 3 groups ((n = 10/group) (Group 1- Predicta®, Group 2- EQUIA Forte® and Group 3- Filtek™ Z350)) was determined at 1st, 4th, 7th and 14th days. After creating artificial carious lesions, human enamel samples were randomly assigned into 3 groups (n = 13/group) which were placed in contact with occluso-proximal restorative materials and exposed to a 14-day pH cycling period. Surface microhardness was determined using a Knoop microhardness assay at baseline, after artificial carious lesions formation and after pH cycling. The difference in the percentage of surface microhardness recovery (%SMHR) among groups was compared. Mineral deposition was analyzed with energy-dispersive x-ray spectroscopy (EDS) and the enamel surface morphology was evaluated with scanning electron microscopy (SEM). Kruskal-Wallis’s test with Dunn’s post hoc test and one-way ANOVA with Tukey’s post hoc test were used for data analysis.ResultsEQUIA Forte® released the highest cumulative amount of F and P ions, followed by Predicta® and Filtek™ Z350. Predicta® released higher amount of Ca ions than EQUIA Forte® and Filtek™ Z350. Predicta® demonstrated the highest %SMHR, followed by EQUIA Forte® and Filtek™ Z350. There was a significant difference in the %SMHR between Predicta® and Filtek™ Z350 (p < 0.05). However, EQUIA Forte® demonstrated the highest fluoride content, followed by Predicta® and Filtek™ Z350. The SEM images of EQUIA Forte® and Predicta® revealed the greater mineral deposition.ConclusionPredicta® demonstrated a marked increase in surface microhardness and fluoride content of adjacent initial interproximal enamel carious lesions in primary molars compared with Filtek™ Z350. Predicta® is an alternative restorative material to remineralize adjacent initial interproximal enamel carious lesions in primary molars, especially in high-risk caries patients.

Do bioactive materials show greater retention rates in restoring permanent teeth than non-bioactive materials? A systematic review and network meta-analysis of randomized controlled trials.

To answer the following research question: does the clinical evaluation of restorations on permanent teeth with bioactive materials show greater retention rates than those with non-bioactive materials? A search strategy was used in the following databases: MEDLINE via PubMed, Scopus, Web of Science, LILACS, BBO, Embase, The Cochrane Library, and OpenGrey. Randomized controlled trials (RCTs), with a minimum of 2-year follow-up and evaluating at least one bioactive material in permanent teeth were included. Risk of bias was detected according to the Cochrane Collaboration tool for assessing the risk of bias (RoB 2.0), and network meta-analysis was performed using a random-effects Bayesian-mixed treatment comparison model. Twenty-seven studies were included. The success of the restorations was assessed using modified USPHS system in 24 studies and the FDI criteria in 3 studies. Network meta-analysis revealed three networks based on restoration preparations. Resin composites were ranked with higher SUCRA values, indicating a greater likelihood of being the preferred treatment for class I, II, and III restorations. In class V, resin-modified glass ionomer cement was ranked with the highest value. Bioactive restorative materials showed similar good clinical performance in terms of retention similarly to conventional resin composites. The findings must be interpreted with caution because many RCT on restorative materials aim to verify the equivalence of new materials over the gold standard material rather than their superiority. The present systematic review also suggests that new RCT with longer follow-up periods are necessary.

Beyond the Clinic: why new bioactive restorative materials have really changed Paediatric Dentistry.

The aim of this paper is to remind how evidence-based paediatric dentistry should not only consider the best available scientific evidence relating to the patient's oral conditions but it should also consider the patient's needs beyond the clinic. In a child-family-oriented approach, the best restorative treatment for a primary tooth could not be the proper one for the child as a whole. Preservation of dental tissues as much as possible, without involving the pulp, is called minimal intervention dentistry (MID) and it is closely related to "selective caries removal" and "bioactive restorative materials". To preserve the vitality of a tooth as much as possible, many tools are available on the market (i.e. silver diamine fluoride, ozone) and this could play an important role in a "tailored fit treatment plan" mindset. Minimally invasive direct restorative strategies in paediatric dentistry, is a predictable evidence-based-restorative option for the treatment of vital primary teeth with no need of local anaesthesia and absolute isolation. Beyond the clinical aspect, the clinician expertise is crucial to evaluate the required materials and tools, not only to perform a minimal invasive paediatric dentistry in a safe, efficient and child-friendly way, but for the wellness of all parties involved. In this life-related paradigm new bioactive restorative materials are among the main protagonists.

Comparative study of two bioactive dental materials

ObjectivesNew bioactive materials were introduced to not only restore the lost dental hard tissue but also to release fluoride that inhibits demineralization and occurrence of secondary caries. The current study thus aims to assess Fluoride release as well as the mechanical and physical properties of two new commercially available bioactive restorative materials. MethodsTwo materials, Cention® Forte (CF) (Ivoclar Vivadent), Surefil one™ (SO) (Denstply Sirona), were evaluated in terms of fracture toughness (FT), flexural strength (FS), flexural modulus (FM) (ISO 4049), compressive strength (CS), and Vickers hardness (VH). In addition, thermogravimetric analysis (TGA) was performed, as well as pH measurements and quantification of Fluoride release after immersion in distilled water at times of 0, 7, 14 and 21 days. The sealing ability was evaluated using silver nitrate dye penetration on natural teeth. Finally, Energy-Dispersive X-Ray Spectroscopy (EDX) was used to investigate the surface composition of the two studied material surfaces. The data were statistically analyzed using Independent T-Tests; the chosen significance level was α = 0.05. ResultsCF had significantly higher FT values compared to SO (p = 0.001). Also the FS results showed that CF had significantly higher values (90.11 MPa), followed by SO (22.15 MPa). The CS values showed the same order with significantly higher values for CF (231.79 MPa). While the FM and VH showed the reverse order with SO having significantly higher values than CF. pH measurements showed that CF evolved towards significantly higher pH values after 3 weeks in distilled water, while thermal properties showed more stability and higher resistance to degradation for CF compared to SO. The silver nitrate penetration results showed significantly better sealing ability for CF compared to the self-adhesive SO. Finally, EDX surface analysis results were consistent with the release profiles and confirmed the composition of the two tested materials. SignificanceBoth materials, demonstrated enhanced Fluoride release ability, and hence good remineralisation potential in vitro that could prevent recurrent carious lesions in vivo. The composition based on acrylic polymerization showed better mechanical resistance to bending and fracture, and higher sealing ability than those based on acid base reaction.

Bioactive restorative materials

Bioactive restorative materials

Comparative Evaluation of Marginal Microleakage of a Bioactive Composite Resin Using Three Different Bonding Agents in Non-Carious Cervical Lesions– An In Vitro Study

Background and objectives: Increasing prevalence of non-carious cervical lesions makes it imperative to overcome challenges in tooth preparation, isolation and restoration. Bio-active restorative materials are relatively new concepts in dentistry having the potential to prevent secondary caries, a major cause of failure of restorations. Composite resins have the disadvantage of polymerization shrinkage leading to marginal gap formation. This study evaluated the marginal microleakage properties of Activa bio-active composite resin using three different adhesives in non- carious cervical lesions. Materials and method: Forty extracted maxillary &amp; mandibular premolars for the study were collected. The specimens were divided into groups (n= 10). Box type class V cavities, 2mm inciso-gingivally, 3mm mesio-distally &amp; 2mm in depth was prepared on the buccal surfaces. Group 1: Activa bio-active resin +No bonding agent, Group 2: Activa bio-active resin +Tetric N-bond, Group 3: Activa bio-active resin +Single bond Universal, Group 4: Activa bio-active resin + G Premio bond. Restorations were done and samples subjected to thermocycling. They were immersed in Rhodamine B dye solution for 24 hours. The samples were longitudinally sectioned in a bucco-lingual direction with diamond discs, examined under a stereo-microscope with 30x magnification and depth of penetration analyzed. The statistical analysis for microleakage was performed using the Kruskal Wallis test followed by the Mann Whitney U-tests with the Wilcoxon correction for pair-wise comparisons at a significance level of p &lt; 0.05. Results: Activa bio-active resin + G Premio bond showed lesser micro-leakage compared to other groups and the difference was statistically significant. Conclusion: Activa bioactive resin with G Premio bond, 8th generation bonding agent showed lesser micro-leakage when compared with 5th and 7th generation bonding agents.

Efficacy of bioactive materials in preventing Streptococcus mutans-induced caries on enamel and dentine.

The study investigated the ability of bioactive materials used to restore enamel and dentine specimens to prevent caries. Enamel (n=50) and dentine (n=50) specimens were obtained from bovine incisors, prepared, and randomly allocated to one of five groups according to the restorative treatment: alkasite without adhesive system; alkasite with adhesive system; high viscosity glass ionomer cement; resin composite; no restoration; negative control group. Specimens were restored, exposed to a thermal cycling aging protocol, sterilized, and exposed to a cariogenic challenge induced by Streptococcus mutans and then submitted to surface and subsurface microhardness tests and polarized light microscopy to verify the caries lesion development in enamel or dentine surrounding the restorative materials. Data were analyzed using one-way ANOVA. In enamel and dentine, glass ionomer cement, alkasite without and with adhesive system presented a lower percentage surface microhardness loss than resin composite and negative control. Enamel subsurface microhardness presented no statistically significant differences between glass ionomer cement, alkasite without and with adhesive system. Glass ionomer cement also did not present statistically significant differences from resin composite and the negative control. In dentine, glass ionomer cement showed the highest subsurface microhardness values. In conclusion, bioactive restorative materials provide greater protection to enamel and dentine against surface caries development than resin composite.

Evaluation of Bioactive Restorative Materials' Color Stability: Effect of Immersion Media and Thermocycling.

One of the most important aspects that determines the clinical lifetime of aesthetic restorations, is the color stability (CS) over the long term. This study aims to assess the effect of artificial aging and thermocycling in different staining solutions on the CS of bioactive restorative materials compared to conventional ones. The following four material groups were investigated: ACTIVA™ Bioactive (AB) (Pulpdent Corporation, Massachusetts, United States), Beautifil II (BF) (SHOFU Inc., Kyoto, Japan), Fuji II (FJ) (GC Corporation, Tokyo Japan), and Filtek™ Z350 XT (FT) (3M, Minnesota, United States). A total of 100 specimens were fabricated using an acrylic mold and then immersed in five staining solutions groups: coffee, black tea, Cola, mixed berry juice, and saline. Baseline shade (T0) was recorded using two spectro-photometer devices, VITA Easyshade® Advance (VITA Zahnfabrik, Baden-Wurttemberg, Germany) and Color-Eye® 7000A (X-Rite, Inc., Grand Rapids, Michigan, United States). Following this, the shade was recorded at 30 days (T1), three months (T2), and after 5000 thermocycles (5C-55C) (T3). CIE L*a*b* (International Commission on Illumination color space) data was used to calculate ΔE for each group. All samples showed a significant color change (P<0.001) following one and three months of storage and after thermocycling. AB and BF showed the highest CS over time, whereas FT and FJ showed the least CS. The CS of restorative materials is mostly determined by their type, followed by staining solution type and thermocycling. The most potent solutions were coffee, tea, and berry juice.

An in vitro Study on the Antibacterial Efficiency of the Various Composites in the Children: An Original Research.

Many generations of esthetic materials have been introduced in the market, the most popular being the composites. Bioactive restorative materials are a recent development in restorative dentistry. However, the main cause of secondary caries is the development of bacterial plaque on these restorations. Current in vitro study was conducted to assess the antibacterial properties of three common composites. Only a single parameter was assessed in this study, which was the bacterial colonies on each of the material blocks that were confined in the same experimental conditions. For this assessment, three composite materials were used that were made into blocks of 10 each. "Beautifil Flow Plus X" and "ACTIVA BioACTIVE" were used as the interventional groups, while "Filtek Z250 XT" was used as the control. Streptococcus mutans was used as an antibacterial test subject, and confocal laser scanning microscopy was used to observe the results. When compared to other groups, ACTIVA BioACTIVE exhibited the highest quantity of dead bacteria on the material surface. There was significant variance among the three composites in the number of live and dead bacterial colonies. The highest antibacterial efficacy among the evaluated materials allows for a conclusion.

Comparison of Shear Bond Strength and Microleakage between Activa™ Bioactive Restorative™ and Bulk-Fill Composites-An In Vitro Study.

Bioactive materials have emerged as a promising alternative to conventional restorative materials as part of more conservative dentistry. The aim of this study was to evaluate and compare the shear bond strength (SBS) and microleakage of a new bioactive restorative material, two bulk-fill restorative composites, and a conventional composite at 24 h, 4 weeks, and 8 weeks. Three hundred and sixty molars and premolars were divided into four groups: ACTIVA™ BioACTIVE Restorative™, Filtek™ Bulk-Fill Restorative Composite, Tetric® N-Ceram Bulk-Fill Composite, and G-aenial® Composite. The normality of the data was determined with the Kolmogorov-Smirnov test, then the two-way ANOVA and Fisher's test were used for analyzing SBS data, and the Kruskal-Wallis and DSCF tests were conducted to analyze the microleakage. In the SBS test, there were no statistically significant differences between materials (p = 0.587), and the relation between material and time (p = 0.467), time points showed statistically significant differences (p = 0.016). As for the microleakage, statistically significant differences were found for all three time periods (p < 0.05), showing the conventional composite to have the lowest microleakage, followed by the bioactive material, and lastly the two bulk-fill composites. In conclusion, the new bioactive material has similar evaluated properties to bulk-fill composites (bond strength) and conventional composites (bond strength and microleakage) and can be used as an alternative restorative material.

Bioactive Restorative Materials Applied over Coronal Dentine-A Bibliometric and Critical Review.

The objective of the research was to examine the scientific literature concerning restorative materials with bioactive properties for the purpose of covering dentin. Searches were performed in various databases including MEDLINE, Scopus, Web of Science, Cochrane Library, Lilacs/BBO, and Embase. Inclusion criteria involved studies that utilized the terms "dentin" and "bioactive", along with "ion-releasing", "smart materials", "biomimetic materials" and "smart replacement for dentin". The information extracted included the title, authors, publication year, journal and the country of affiliation of the corresponding author. The studies were categorized based on their study design, type of material, substrate, analytical method, and bioactivity. A total of 7161 records were recovered and 159 were included for data extraction. Most of the publications were in vitro studies (n = 149), testing different types of materials in sound dentine (n = 115). Most studies were published in Dental Materials (n = 29), and an increase in publications could be observed after the year 2000. Most of the articles were from the USA (n = 34), followed by Brazil (n = 28). Interfacial analysis was the most investigated (n = 105), followed by bond strength (n = 86). Bioactivity potential was demonstrated for most tested materials (n = 148). This review presents insights into the current trends of bioactive materials development, clearly showing a severe lack of clinical studies.

Clinical efficacy of bioactive restorative materials in controlling secondary caries: a systematic review and network meta-analysis

BackgroundThis systematic review and network meta-analysis aimed to compare the clinical efficacy of bioactive and conventional restorative materials in controlling secondary caries (SC) and to provide a classification of these materials according to their effectiveness.MethodsA search was performed in Pubmed, Web of Science, Embase, BBO, Lilacs, Cochrane Library, Scopus, IBECS and gray literature. Clinical trials were included, with no language or publication date limitations. Paired and network meta-analyses were performed with random-effects models, comparing treatments of interest and classifying them according to effectiveness in the permanent and deciduous dentition and at 1-year or 2/more years of follow-up. The risk of bias and certainty of evidence were evaluated.ResultsSixty-two studies were included in the qualitative syntheses and 39 in the quantitative ones. In permanent teeth, resin composite (RC) (RR = 2.00; 95%CI = 1.10, 3.64) and amalgam (AAG) (RR = 1.79; 95%CI = 1.04, 3.09) showed a higher risk of SC than Glass Ionomer Cement (GIC). In the deciduous teeth, however, a higher risk of SC was observed with RC than with AAG (RR = 2.46; 95%CI = 1.42, 4.27) and in GIC when compared to Resin-Modified Glass Ionomer Cement (RMGIC = 1.79; 95%CI = 1.04, 3.09). Most randomized clinical trials studies showed low or moderate risk of bias.ConclusionThere is a difference between bioactive restorative materials for SC control, with GIC being more effective in the permanent teeth and the RMGIC in the deciduous teeth. Bioactive restorative materials can be adjuvants in the control of SC in patients at high risk for caries.

Effect of Antibacterial Agents on Dentin Bond Strength of Bioactive Restorative Materials.

Treating dentin surfaces with antibacterial agents prior to bonding bioactive restorations might affect their mechanical properties. In this study, we evaluated the effect of silver diamine fluoride (SDF) and chlorhexidine (CHX) on the shear bond strength (SBS) of bioactive restorative materials. Dentin discs were treated with SDF for 60 s or CHX for 20 s and bonded with four restorative materials, namely Activa Bioactive Restorative (AB), Beautifil II (BF), Fuji II LC (FJ), and Surefil One (SO). Control discs were bonded without treatment (n = 10). SBS was determined using a universal testing machine, and a scanning electron microscope (SEM) was used for the evaluation of the failure mode and the cross-sectional examination of adhesive interfaces. The SBS of each material between different treatments and of the different materials within each treatment were compared via a Kruskal-Wallis test. The SBS of AB and BF was significantly higher than that of FJ and SO in the control and CHX groups (p < 0.01). In the latter, SBS was higher in FJ than SO (p < 0.01). SO had a higher value with SDF compared to CHX (p = 0.01). The SBS of SDF-treated FJ was higher than that of the control (p < 0.01). SEM showed a more homogenous and improved interface of FJ and SO with SDF. Neither CHX nor SDF compromised the dentin bonding of bioactive restorative materials.

Evaluation of Antibacterial Activity of a Bioactive Restorative Material Versus a Glass-Ionomer Cement on Streptococcus Mutans: In-Vitro Study.

Dental caries management consists of both preventive and restorative approaches. Pediatric dentists can rely on many techniques and materials to restore decayed teeth, but a high failure rate is still observed, mainly due to secondary caries. New restorative bioactive materials combine the mechanical and aesthetic characteristics of resinous materials with the capability to remineralize and the antimicrobial properties of glass ionomers, thus counteracting the occurrence of secondary caries. The aim of this study was to assess the antimicrobial activity against Streptococcus mutans of a bioactive restorative material (ACTIVA™ BioActive-Restorative™-Pulpdent©) and a glass ionomer cement with silver particles added (Ketac™ Silver-3M©), using agar diffusion assay. Each material was formed into disks of 4 mm in diameter, and four discs of each material were placed on nine agar plates. The analysis was repeated seven times. Both materials showed statistically significant growth inhibition properties against S. mutans (p < 0.05). The difference in the effectiveness of the two materials was not statistically significant. Both ACTIVA™ and Ketac™ Silver can be recommended since both are similarly effective against S. mutans. However ACTIVA™, given its bioactivity and better aesthetics and mechanical properties compared to GICs, may provide better clinical performance.

COMPARATIVE EVALUATION OF FLUORIDE RELEASE FROM A COMPOMER, A GIOMER AND A CONVENTIONAL GIC

Purpose: The aim of the study was to measure and compare the release of fluoride ions from three bioactive restorative materials used for restorations in primary dentition - conventional GIC Fuji IX GP Extra, compomer Dyract and giomer Beautifil II. Materials and methods: 20 samples with a diameter of 6 mm and a thickness of 2 mm were made from the tested materials. At the beginning of the test, all samples were immersed in 5 ml of deionized water and placed in an incubator for 24 hours at 37°C ± 0.5°C. After 24 hours, the concentration of fluoride ions in the medium was measured with an ion-selective electrode for fluorides connected to an ion meter. During this time, the removed cylindrical samples were washed with fresh deionized water, dried, and transferred to new vials with 5 ml of fresh deionized water. The described procedure was repeated every day for a week and then on the 14th, 21st and 28th days. Results: GIC outperformed compomer and giomer in terms of fluoride ions release for all time intervals with a statistically significant difference. The difference between compomer and giomer was not reliable, but compomer demonstrated higher values ​​for all time intervals. Conclusion: All studied materials released fluoride ions during the entire experimental period, with the highest concentrations being recorded on the first day of the study. GIC outperformed compomer and giomer many times in terms of fluoride release for all time intervals.