Biophysiological Parameters Research Articles

Impact of Knack Manoeuvre Among Women with Urinary Incontinence: A Quasi Experimental Study

ABSTRACT Objective: The Objective of the study is to assess the effectiveness of Knack manoeuvre among women with urinary incontinence. Methods: A quasi-experimental study with a repeated measures design was used to conduct study at Saveetha Medical College Hospital. Experimental group received Knack manoeuvre for 6 months and control group received routine care. The sample size was 100, which was recruited by purposive sampling technique. The data were collected with structured questionnaire, and questionnaire for urinary incontinence diagnosis and biophysiological parameters were assessed by abdominal leak peak pressure (ALPP). Results: The study results depict that frequency and percentage distribution of pretest and post-test level of ALPP. Between group comparison of post-test at 6 months of control and experimental showed significance (P < 0.001). There was a progressive decrease in ALPP of control and experimental groups. Conclusion: To our knowledge, this is the first prospective nonrandomized study that assesses the efficacy of the Knack manoeuvre on urine incontinence by assessing biophysiological parameters.

Gamma rays and sodium azide induced variations in bio-physiological and agronomical traits in linseed (Linum usitatissimum L.)

Linseed is a valuable oilseed crop with huge therapeutic importance due to its high content of omega-3 fatty acids in the form of Alpha-linolenic acid (ALA). It is a self-pollinated crop with a low-yielding potential that restricts its improvement endeavors. To overcome low-yielding potential, individual and combination treatments of gamma rays and sodium azide were employed in widely grown linseed varieties. The results revealed a dose-dependent decline in seed germination, seedling height, pollen fertility, chlorophyll, and carotenoid contents and a dose-independent decline in carbonic anhydrase activity. Bio-physiological parameters decreased substantially in combination treatments compared to individual treatments of gamma rays and sodium azide. In contrast, lower doses of gamma rays, sodium azide, and their combinations effectively increased mean values of yield and yield-attributing traits in a few putative mutants. Such putative mutants represent a valuable genetic resource that could be used in future breeding programs for the genetic improvement of linseed and related medicinal plants.

A STUDY TO ASSESS THE EFFECT OF CRYOTHERAPY ON PAIN AND SELECTED BIOPHYSIOLOGICAL PARAMETERS DURING ARTERIOVENOUS FISTULA CANNULATION AMONG PATIENTS ON MAINTENANCE HAEMODIALYSIS

The current study entitled a study to assess the effect of Cryotherapy on pain and selected Biophysiological parameters during arteriovenous fistula cannulation among patients on maintenance Hemodialysis at KMCH, Coimbatore was undertaken, during the year 2010 - 2011 in partial fulfillment of the requirement for the degree of Master of Science in Nursing at KMCH College of Nursing, Coimbatore which is affiliated to Dr. M.G.R. Medical University, Chennai. Objectives: To assess the pain intensity during Xylocaine infiltration. To determine the effect of Cryotherapy on pain and Biophysiological parameters during AV fistula cannulation. To associate the level of pain with selected demographic variables. Design: Repeated Measures design. Setting: Hemodialysis unit of Kovai Medical Center and Hospital, Coimbatore. Sample: Sample size was 50. Conceptual framework: Modified Orlando‟s Nursing process model. Outcome measures: The demographic data was collected from the subjects. The pain intensity was measured during cannulation with Xylocaine and with Cryotherapy using Numerical Pain rating Scale. The investigator recorded the Biophysiological parameters during the procedure. Intervention: Cold application was done prior and during cannulation over on the web between the thumb and index finger of the hand which does not have the AV fistula. Results: The mean pain score with Xylocaine infiltration at arterial site was 4.81 and at the venous site was 4.86.There was a significant reduction in the pain score during cannulation with the application of Cryotherapy. The mean pain score during cannulation after Xylocaine at the arterial site was 1.59 and at the venous site was 1.51 whereas the mean pain score during cannulation after Cryotherapy was 0.96 and 0.92 correspondingly. But there was no statistically significant difference between the values of Biophysiological parameters such as BP, PR and RR during cannulation done with Xylocaine and with Cryotherapy. There was no significant association between pain score and age and gender of the subjects but there was significant association between pain and duration of illness and duration of treatment Conclusion: Cryotherapy is an effective nonpharmacological measure in reducing pain during AV fistula cannulation among Hemodialysis patients.

A randomized controlled trial of the size-adjustable cryoballoon vs conventional cryoballoon for paroxysmal atrial fibrillation: The CONTRAST-CRYO II trial rationale and design

BackgroundPulmonary vein isolation (PVI) with cryoballoon technology is a well-established therapy for atrial fibrillation (AF) patients. Most recently, a size-adjustable cryoballoon (POLARx FIT) that enables delivery as a standard 28mm or expanded 31mm size was introduced. ObjectiveThe study sought to perform a randomized clinical trial to evaluate the safety and efficacy of this novel cryoballoon as compared to the conventional cryoballoon. MethodsThe CONTRAST-CRYO II trial is a multicenter, prospective, open-label, randomized controlled trial in which 214 patients with paroxysmal AF will be randomized 1:1 to receive cryoballoon ablation with either a conventional cryoballoon (Arctic Front AdvanceTM Pro) or size-adjustable cryoballoon. This study was approved by the Institutional Review Boards at all investigational sites and has been registered in the UMIN Clinical Trials Registry (UMIN000052500). ResultsThe primary endpoint of this study will be the incidence of phrenic nerve injury. The secondary endpoints include the procedure success, chronic success through 12 months, procedure-related adverse events, biophysiological parameters during applications for each PV, total procedure and fluoroscopy time, level of the PVI and isolation area, and probability of non-PV foci initiating AF. ConclusionThe CONTRAST-CRYO II trial is a multicenter, prospective, randomized controlled trial designed to assess the safety and efficacy of the POLARxTM FIT by comparing the AFA-Pro. The findings from this trial will provide additional utility data on the efficacy of the size-adjustable cryoballoon for isolating pulmonary veins in patients with paroxysmal AF.

A Study to Evaluate the Effectiveness of Hypertonic Saline Nebulized Suctioning on Bio Physiological Pulmonary Parameters among Patient with A Mechanical Ventilator at A Selected Hospital, Meerut

A Study to Evaluate the Effectiveness of Hypertonic Saline Nebulized Suctioning on Bio Physiological Pulmonary Parameters among Patient with A Mechanical Ventilator at A Selected Hospital, Meerut

Effect of Moringa oleifera soup on selected biophysiological parameters among adult with hypercholesterolemia working in selected tertiary care hospital

Effect of Moringa oleifera soup on selected biophysiological parameters among adult with hypercholesterolemia working in selected tertiary care hospital

Home-based cardiac rehabilitation: development, implementation and outcome evaluation in patients with coronary artery diseases in Lahore, Pakistan – a mixed-methods study protocol

IntroductionCardiac rehabilitation (CR) is an important strategy to bring cardiac patients back to a normal life after a cardiac event. The benefits of CR as part of secondary prevention are...

Insufficient oxygen inhalation during cardiopulmonary resuscitation induces early changes in hemodynamics followed by late and unfavorable systemic responses in post-cardiac arrest rats.

Cardiac arrest (CA) and concomitant post-CA syndrome lead to a lethal condition characterized by systemic ischemia-reperfusion injury. Oxygen (O2 ) supply during cardiopulmonary resuscitation (CPR) is the key to success in resuscitation, but sustained hyperoxia can produce toxic effects post CA. However, only few studies have investigated the optimal duration and dosage of O2 administration. Herein, we aimed to determine whether high concentrations of O2 at resuscitation are beneficial or harmful. After rats were resuscitated from the 10-min asphyxia, mechanical ventilation was restarted at an FIO2 of 1.0 or 0.3. From 10 min after initiating CPR, FIO2 of both groups were maintained at 0.3. Bio-physiological parameters including O2 consumption (VO2 ) and mRNA gene expression in multiple organs were evaluated. The FIO2 0.3 group decreased VO2 , delayed the time required to achieve peak MAP, lowered ejection fraction (75.1 ± 3.3% and 59.0 ± 5.7% with FIO2 1.0 and 0.3, respectively; p < .05), and increased blood lactate levels (4.9 ± 0.2 mmol/L and 5.6 ± 0.2 mmol/L, respectively; p < .05) at 10 min after CPR. FIO2 0.3 group had significant increases in hypoxia-inducible factor, inflammatory, and apoptosis-related mRNA gene expression in the brain. Likewise, significant upregulations of hypoxia-inducible factor and apoptosis-related gene expression were observed in the FIO2 0.3 group in the heart and lungs. Insufficient O2 supplementation in the first 10 min of resuscitation could prolong ischemia, and may result in unfavorable biological responses 2 h after CA. Faster recovery from the impairment of O2 metabolism might contribute to the improvement of hemodynamics during the early post-resuscitation phase; therefore, it may be reasonable to provide the maximum feasible O2 concentrations during CPR.

Competency based performance of mothers on preterm neonatal care through Neonatal Integrative Developmental Care (NIDC) interventions: An interventional pilot project

BackgroundFamily-centered care and developmentally supportive care are the current norms in Neonatal Intensive Care Units (NICU). In this study, interventions are derived from the seven core measures of the Neonatal integrative developmental care (NIDC) model designed by Altimier and Phillips (2016) which strive towards protection of premature brains while in the NICU. This study involved mothers in the care of their preterm neonates. Neonatal outcomes and competency levels in the care delivered by the mothers when handling their preterm infants were observed. Materials and methodsA quasi experimental time series design study with repeated interventions was undertaken. The pilot study was conducted among 60 mothers with 30 in the interventional group and 30 in the control group at two private hospitals, Mangaluru, Karnataka, India. The tool consisted of a baseline proforma, competency based performance rating scale, biophysiological parameters checklist, preterm infant behavior scale by D'Souza et al. (2014) and Preterm Infant Breastfeeding Behavior Scale by Nyqvist et al. (1999) validated by 10 experts. Purposive sampling technique was used to select the samples. ResultsThe findings of the study showed that the competencies delivered by mothers in the interventional group were statistically significant (p = 0.000). Neonatal biophysiological parameters improved in terms of oxygen saturation (p = 0.007) and respiratory rate (p = 0.002) in the experimental group, and weight gain (p = 0.001) was noted in both the groups respectively. Preterm infant behavior (p = 0.001) and PIBBS scores (p = 0.001) also improved in both groups simultaneously with no significant difference in behavioral states but the PIBBS scores were significantly better in the interventional group (p = 0.001). ConclusionsOur study findings revealed the need for supportive care interventions that can be performed through simple measures, such as helping mothers and care-givers become a part of their neonate's life by participating in their care while in the NICU.

Effect of yoga on bio-physiological parameters among overweight and obese adolescents: a case series study

The number of overweight and obese children in India was 19.3% (NFHS-5), which was a big jump from the previous number of 6.3% (NFHS-4). A school-based case-series design was conducted to assess the effect of yoga on biophysiological parameters among overweight and obese adolescents (11-13 years) at selected schools in Puducherry. The census method was used to screen 286 adolescents, aged 11 to 13, for height and weight. The study included 18 overweight boys and girls. Bio-physiological parameters were measured at baseline, three months, and six months after yoga practice. The results of the study showed that a significant difference was found after yoga practice. The mean difference in weight reduction was 4.0, the BMI was 1.7, the waist circumference was 4.6, the hip circumference was 6.2, the triceps skin fold thickness was 4.9, and the sub capsular skin fold thickness was 5.7. The mean difference in pulse reduction was 8.8, the systolic blood pressure was 11.0, and the diastolic pressure was 6.9. In terms of body composition, the decrease in fat (%) was 3.4, water (%) was 2.4, extracellular volume (ECW) (%) was 1.1, intracellular volume (ICW) (%) was 2.0, and the body fat mass index (BFMI) was 1.7. The study concluded that yoga is effective in managing obesity and building healthy citizens in future adolescents.

A Study to Assess the Effectiveness of Nesting on Bio-Physiological Parameters

In the present study, the researcher had adopted Quantitative research approach. Pretest posttest control group design was adopted in this study. . Urmila Chaudhari The data were organized, analyzed and interpreted using descriptive and inferential statistics. The demographic variables of mother and baby and the distribution of sucking response among low birth weight babies were tabulated by using frequency distribution. The effectiveness of nesting and comparison between pretest, posttest I and posttest II scores on bio-physiological parameters and sucking response were analyzed by using ANOVA and Z test. It was found that the values were statistically significant at 5% level.

EFFECT OF EARLY AMBULATION ON MATERNAL OUTCOME AMONG POST CAESAREAN MOTHERS

The purpose of the study was to determine the effect of early ambulation on maternal outcome among post caesarean mothers. The objectives of the study was to assess the effect of early ambulation on maternal outcome among post caesarean mothers and to nd out the association between the maternal outcome among post caesarean mothers with selected demographic variables. This study was based on Roy's adaptation theory. The research design adopted for the study was post-test only control group design. 60 post caesarean mothers who fullled the inclusion criteria were selected for the study, out of which 30 post caesarean mothers were in experimental group and 30 post caesarean mothers were in control group. Non-probability purposive sampling technique was used to select the samples. The tool used to assess the effect of early ambulation was post caesarean bio physiological health parameters chart. The study was conducted in General Hospital, Neyyattinkara. The effectiveness of early ambulation was assessed by comparing the maternal outcome of post caesarean mothers in experimental group and control group. The result shows that there was a signicant difference in the maternal outcome among post caesarean mothers in the experimental group after performing early ambulation and there was an association between the maternal outcome among post caesarean mothers with selected demographic variables except in case of period of gestation

Effectiveness of Nesting and Swaddling Technique on Biophysiological Parameters, Neuro-behavioral Activity, and Sucking Response among Sick Neonates of Selected Pediatrics Units of Navi Mumbai

Aim: This study examined the effects of Nesting and Swaddling on bio-physiological parameters, neuro-behavioural activity, and sucking reflex in ill neonates. Method: The researcher used a quantitative and quasi-experimental approach in this investigation. The study included sick Neonates in pediatric unit of selected hospitals Navi Mumbai. Sample size for the study is 200. Result: The experimental normal delivery group reported 56% temperatures over 99.3F. The experimental cesarean group had 54% temperatures over 99.3 F. Sick neonates have mean neuro-behavioral activity of 1.88 with SD 0.89 in the experimental normal delivery group and 1.84 with SD 0.86 in the experimental caesarean group. Sucking response of sick neonates shows 44% of experimental normal delivery group has poor feed. About 54% of experimental cesarean patients were inadequately fed. About 70% of experimental normal delivery group had 97.5–99.3 F. After Nesting and Swaddling, 60% of experimental caesarean delivery patients had 97.5–99.3 F. After nesting and swaddling, sick babies’ neuro-behavioural activity is 2.96 with SD 1.45 in the experimental normal birth group and 3.5 with SD 1.16 in the experimental cesarean group. After nesting and swaddling, 68% of experimental normal birth group sick babies had reasonably effective feed by post-test sucking. At least 50% of experimental cesarean birth patients had effective feed. Conclusion: This study shows that nesting and swaddling sick neonates improves biophysiological measures, neuro-behavioural activity, and sucking reflex. Sick newborns’ biophysiological measurements, neuro-behavioural activity, and sucking response score improve.

Effectiveness of Nesting and Swaddling Technique on Bio-physiological Parameters, Neuro-behavioral Activity and Sucking Response among Sick Neonates

Babies delivered before 37 weeks or 259 days of gestation are deemed premature. It is believed to be the direct cause of 24% of infant fatalities. While preterm births account for between 5% and 7% of all live births in some developed nations, it is believed that the proportion is much higher in developing nations. Nearly 30% of infants in India, or 7.5 million, are born low birth weight (LBW) (2500 g). This accounts for 42% of the global burden, more than any other nation. Approximately 60% of LBW neonates are born at term after fetal growth restriction, while the remaining 40% are born prematurely. The prevalence of SGA is 46.9%, exceeding all countries except two. Nesting is one of the most important factors in maintaining a healthy position for a premature infant, which involves positioning the hands near the face and the feet together while using positioning aids to create a secure, snug, and supportive nest. The capacity to nest keeps premature neonates in a comfortable position, enables spontaneous motor activity for skeletal joint and neuromuscular function, and facilitates the monitoring of stable vital signs. Commonly, infants are wrapped in a breathable, lightweight blanket to help them unwind and fall asleep.

Rehabilitation in digital environments – biophysiologically motivated gamification

Nowadays, the process of cognitive or motor rehabilitation is mostly implemented in a traditional form. Paper-pencil cognitive exercises or physical exercises with instruments still dominate over digital environments. However, they require constant supervision by professionals, whose availability is relatively decreasing in an ageing society. Lack of supervision, in turn, results in a loss of motivation to exercise or, at the very least, ineffective, sometimes incorrect, exercise. In addition, traditional rehabilitation mechanisms are often repetitive and tedious. Sometimes a lack of supervision or routine results in a failure to adapt the challenges to the user's current needs.&#x0D; Digital environments and modern technology have much to offer in this regard. One aspect is gamification mechanisms, which work well in video games and allow players to be engaged for hours in challenges of modulated difficulty. Another aspect is the rapidly developing biosensors and tracking systems that allow the user's activity and biophysiological parameters to be monitored in real time. However, the combination of the benefits of technology and gamification stimulus mechanisms must be done in strict accordance with the user's capabilities in order to make the challenges constructive rather than destructive for the user's body and mental conditions. Ongoing monitoring of effort and mental workload and their synchronization with fatigue in the digital environment, supported by motivational gamification mechanisms, form the foundation of the correct and controlled exercises and rehabilitation.

Effectiveness of dual nursing interventions on anxiety, pain and bio-physiological parameters among patients undergoing cardiac surgery

Effectiveness of dual nursing interventions on anxiety, pain and bio-physiological parameters among patients undergoing cardiac surgery

Antidiabetic Effect of Millet Bran Polysaccharides Partially Mediated via Changes in Gut Microbiome.

Diabetes is a type of metabolic disease associated with changes in the intestinal flora. In this study, the regulatory effect of millet bran on intestinal microbiota in a model of type 2 diabetes (T2DM) was investigated in an effort to develop new approaches to prevent and treat diabetes and its complications in patients. The effect of purified millet bran polysaccharide (MBP) with three different intragastric doses (400 mg/kg, 200 mg/kg, and 100 mg/kg) combined with a high-fat diet was determined in a streptozotocin (STZ)-induced model of T2DM. By analyzing the changes in indicators, weight, fasting blood sugar, and other bio-physiological parameters, the changes in gut microbiota were analyzed via high-throughput sequencing to establish the effect of MBP on the intestinal flora. The results showed that MBP alleviated symptoms of high-fat diet-induced T2DM. A high dosage of MBP enhanced the hypoglycemic effects compared with low and medium dosages. During gavage, the fasting blood glucose (FBG) levels of rats in the MBP group were significantly reduced (p &lt; 0.05). The glucose tolerance of rats in the MBP group was significantly improved (p &lt; 0.05). In diabetic mice, MBP significantly increased the activities of CAT, SOD, and GSH-Px. The inflammatory symptoms of liver cells and islet cells in the MBP group were alleviated, and the anti-inflammatory effect was partially correlated with the dose of MBP. After 4 weeks of treatment with MBP, the indices of blood lipid in the MBP group were significantly improved compared with those of the DM group (p &lt; 0.05). Treatment with MBP (400 mg/kg) increases the levels of beneficial bacteria and decreases harmful bacteria in the intestinal tract of rats, thus altering the intestinal microbial community and antidiabetic effect on mice with T2DM by modulating gut microbiota. The findings suggest that MBP is a potential pharmaceutical supplement for preventing and treating diabetes.

Effectiveness of selected Maternal Positions Onbiophysiological Parameters of Antenatal Mothers and Fetus During Non Stress Test

Non-Stress test is a non-invasive test performed over 28 week of gestation for detection of ante partum fetal surveillance. Maternal positioning can have an impact on both the mother’s and fetal physiological well-being. Objective: Assess and compare the effectiveness of maternal positions on bio physiological parameters of the fetus during NST. Methods: Quantitative quasi-experimental pretest, posttest only research design, 60 mothers were selected by random sampling technique. Maternal, fetal bio physiological parameters tool was used. The mothers were placed in left lateral, supine position while performing NST and fetal parameters were monitored and interpreted. Mother vitals also monitored. Results: The post test score of fetal reaction in supine was 4.20±1.16 and in lateral 4.90±0.31. The calculated independents’ test value of t = 3.205 was found to be statistically significant at p&lt;0.01 level. Conclusion: This reveals that the left lateral position is highly effective position for the mother while performing NST.

A Study to Evaluate Pranayama on Bio Physiological Parameters Among Patients with Bronchial Asthma at NMCH, Nellore

A Study to Evaluate Pranayama on Bio Physiological Parameters Among Patients with Bronchial Asthma at NMCH, Nellore

Heart Rate Measurement Accuracy of Fitbit Charge 4 and Samsung Galaxy Watch Active2: Device Evaluation Study.

BackgroundFitness trackers and smart watches are frequently used to collect data in longitudinal medical studies. They allow continuous recording in real-life settings, potentially revealing previously uncaptured variabilities of biophysiological parameters and diseases. Adequate device accuracy is a prerequisite for meaningful research.ObjectiveThis study aims to assess the heart rate recording accuracy in two previously unvalidated devices: Fitbit Charge 4 and Samsung Galaxy Watch Active2.MethodsParticipants performed a study protocol comprising 5 resting and sedentary, 2 low-intensity, and 3 high-intensity exercise phases, lasting an average of 19 minutes 27 seconds. Participants wore two wearables simultaneously during all activities: Fitbit Charge 4 and Samsung Galaxy Watch Active2. Reference heart rate data were recorded using a medically certified Holter electrocardiogram. The data of the reference and evaluated devices were synchronized and compared at 1-second intervals. The mean, mean absolute error, mean absolute percentage error, Lin concordance correlation coefficient, Pearson correlation coefficient, and Bland-Altman plots were analyzed.ResultsA total of 23 healthy adults (mean age 24.2, SD 4.6 years) participated in our study. Overall, and across all activities, the Fitbit Charge 4 slightly underestimated the heart rate, whereas the Samsung Galaxy Watch Active2 overestimated it (−1.66 beats per minute [bpm]/3.84 bpm). The Fitbit Charge 4 achieved a lower mean absolute error during resting and sedentary activities (seated rest: 7.8 vs 9.4; typing: 8.1 vs 11.6; laying down [left]: 7.2 vs 9.4; laying down [back]: 6.0 vs 8.6; and walking slowly: 6.8 vs 7.7 bpm), whereas the Samsung Galaxy Watch Active2 performed better during and after low- and high-intensity activities (standing up: 12.3 vs 9.0; walking fast: 6.1 vs 5.8; stairs: 8.8 vs 6.9; squats: 15.7 vs 6.1; resting: 9.6 vs 5.6 bpm).ConclusionsDevice accuracy varied with activity. Overall, both devices achieved a mean absolute percentage error of just <10%. Thus, they were considered to produce valid results based on the limits established by previous work in the field. Neither device reached sufficient accuracy during seated rest or keyboard typing. Thus, both devices may be eligible for use in respective studies; however, researchers should consider their individual study requirements.