Bibliometric Analysis Research Articles

A bibliometric analysis of the application of the PI3K-AKT-mTOR signaling pathway in cancer.

PI3K-AKT-mTOR plays as important role in the growth, metabolism, proliferation, and migration of cancer cells, and in apoptosis, autophagy, inflammation, and angiogenesis in cancer. In this study, the aim was to comprehensively review the current research landscape regarding the PI3K-AKT-mTOR pathway in cancer, using bibliometrics to analyze research hotspots, and provide ideas for future research directions. Literature published on the topic between January 2006 and May 2023 was retrieved from the Web of Science core database, and key information and a visualization map were analyzed using CiteSpace and VOSviewer. A total of 5800 articles from 95 countries/regions were collected, including from China and the USA. The number of publications on the topic increased year on year. The major research institution was the University of Texas MD Anderson Cancer Center. Oncotarget and Clinical Cancer Research were the most prevalent journals in the field. Of 26,621 authors, R Kurzrock published the most articles, and J Engelman was cited most frequently. "A549 cell," "first line treatment," "first in human phase I," and "inhibitor" were the keywords of emerging research hotspots. Inhibitors of the PI3K-AKT-mTOR pathway and their use in clinical therapeutic strategies for cancer were the main topics in the field, and future research should also focus on PI3K-AKT-mTOR pathway inhibitors. This study is the first to comprehensively summarize trends and development s in research into the PI3K-AKT-mTOR pathway in cancer. The information that was obtained clarified recent research frontiers and directions, providing references for scholars of cancer management.

Past and present discovery of the BAFF/APRIL system – A bibliometric study from 1999 to 2023

Cytokines from the Tumour Necrosis Factor (TNF) family are important regulators of both physiological and pathological processes. The discovery of novel TNF ligands and receptors, BAFF and APRIL, have opened up new possibilities for scientists to explore the effect of these cytokines on the human immune system. The role of BAFF/APRIL system in B lymphocytes is particularly important for survival and maintenance of homeostasis. Aberrant expression of the system is associated with various immunological disorders. Hence, this study provides a comprehensive overview of the past and present BAFF/APRIL system research development in a bibliometric perspective. To our best knowledge, this is the first ever bibliometric analysis conducted focusing on the BAFF/APRIL system. A total of 1055 relevant documents were retrieved from WoSCC. Microsoft Excel, VOSviewer, and Biblioshiny of R studio were bibliometric tools used to analyse the scientific literature. From 1999, the annual publications showed an upward trend, with Journal of Immunology being the most productive journal. USA leads the race for BAFF/APRIL system research developments. Pascal Schneider, a senior researcher affiliated with University of Lausanne, Switzerland was recognised as the most productive author and institution in the BAFF/APRIL system research field. The research focus transitioned from focusing on the role of the system in B cell biology, to immunological disorders and finally to development of BAFF/APRIL targeting drugs. Despite several studies elucidating briefly the pathway mechanism of BAFF/APRIL system in B-cell selection, substantial research on the mechanism of action in disease models and T cell activation and development of immunomodulating drugs from natural origins remains largely unexplored. Therefore, future research focusing on these areas are crucial for the deeper understanding of the system in disease manifestations and progression allowing a better treatment management for various immunological disorders.

Updated research trend and clustering algorithm on virtual reality and pulmonary rehabilitation: Scopus-based bibliometric and visual analysis

Background: Virtual reality (VR) is a new innovative technology that can enhance intervention and should promote the effectiveness of rehabilitation, but there is a lack of scientific evidence on the clustering and topic research trend, especially on VR and pulmonary rehabilitation (PR). More evidence about network clusters and trends will encourage the research in the future. Objective: This study aimed to explore, identify, cluster, and forecast analysis for the research trend of VR and PR from the research articles on the SCOPUS database. Materials and methods: In this study, the search terms “virtual reality” AND “pulmonary rehabilitation” were extracted from specific English research articles published on the SCOPUS database between 2013-2023. RStudio software was used to perform bibliometric and visual analysis. During the analysis in the bibliometric tool, the normalization process with Salton’s Cosine and network clustering via trend topic with the Walktrap algorithm was analyzed before specific visualization with the network clustering mapping, Treemap, and trend topic line by KamadaKawai layout algorithm. Results: From the 1,396 articles on “VR” published between 2010 and 2023, there were 13 research articles on “VR AND PR” published between 2013 and 2023. The bibliometric result from 13 articles showed total of 36 subdisciplines correlated networks among virtual reality (20, 7%), male (16, 6%), female (15, 5%), aged (12, 4%), chronic obstructive lung disease (12, 4%), exercise (11, 4%), human (10, 4%), humans (10, 4%), middle-aged (10, 4%), quality of life (10, 4%), article (9, 3%), pulmonary rehabilitation (9, 3%), controlled study (8, 3%), adult (6, 2%), chronic obstructive (6, 2%), clinical article (6, 2%), forced expiratory volume (6, 2%), pulmonary disease (6, 2%), randomized controlled trial (6, 2%), and forced vital capacity (5, 2%), etc., respectively. Three network clusters were reported after the normalization process and clustering evaluation by factorial analysis. The first cluster was composed of virtual reality, male, female, aged, chronic obstructive lung disease, exercise, human, humans, middle-aged, quality of life, article, pulmonary rehabilitation, controlled study, adult, chronic obstructive, clinical article, forced expiratory volume, randomized controlled trial, forced vital capacity, six-minute walk test, depression, technology, telerehabilitation, breathing exercise, Covid-19, dyspnea, functional status, hospital patient, and physical activity, respectively. The second cluster consisted of procedure and exercise therapy, and the last cluster consisted of exercise tolerance, lung, treatment outcome, health program, and convalescence. Finally, trend research topics were presented in virtual reality, male, female, aged, chronic obstructive lung disease, human, exercise, quality of life, and middle-aged, respectively, in 2023. Conclusion: Therefore, the contribution from data analysis in this article can identify the clustering and trend topics of VR, chronic obstructive lung disease, aging participants, exercise, and quality of life in future research.

Use of waste plastic oil as a fuel in reactivity-controlled compression ignition engines: a bibliometric investigation from 2017–23

Abstract Waste plastic oil, generated through the pyrolysis of plastic without oxygen, known as plastic-to-fuel conversion, stands as a promising alternative fuel. This research employs bibliometric analysis, a quantitative method, to comprehensively assess publications in the domain of waste plastic oil integration within reactivity-controlled compression ignition engines. Utilizing Scopus as the primary repository post-2017, the study categorizes information into pivotal aspects, including influential journals, countries, authors, affiliations, document types, thematic areas, sponsors and keywords. The analysis reveals significant contributions from diverse nations, prominently India, China, Turkey and Malaysia. Noteworthy is the prevalence of Energy, Engineering and Chemical Engineering as thematic focal points, with the journal Fuel leading the count followed by the journal Energy emerging as a prominent conduit. Institutional contributions are prolific, led by Gandhi Institute of Technology and Management University and Vellore Institute of Technology. Renowned authors ‘Gugulothu S.K’ and ‘He Z’ play a pivotal role in shaping the discourse. The National Natural Science Foundation of China stands out as a primary patron. This bibliometric analysis provides a structured understanding of waste plastic oil integration in reactivity-controlled compression ignition engines, laying the groundwork for future research avenues. The study identifies potential research platforms beyond Scopus, including Web of Science, CrossRef, Science Direct and Google Scholar, as valuable repositories for further exploration. Moreover, after careful observation of the research articles published by the top 10 authors as found in the study, it was found that the authors share a few common characteristics that helped them in advancing the understanding and application of waste plastic oil in reactivity-controlled compression ignition engines. These are also summarized in the present study with supporting data.

Understanding Tibetan Exile: a review of literature and bibliometric analysis (1960-2021)

ABSTRACT This research aims to use VOSviewer to undertake bibliometric analysis to map the primary areas of Tibetan Exile literature to create a taxonomy of topic subareas and a research plan on this issue. Two hundred eighty-one papers published between 1960 and 2021, which were extracted from the Scopus database, have been examined to evaluate their interconnection, clusters, and citations to build a text-based map. The study highlights the most cited document, essential journals publishing on the issue, important keywords, prominent authors, and discussions on Tibetan refugees; also classifying the subthemes and the leading author’s name. The findings will guide researchers interested in contemporary Tibetan studies. This categorization table of subthemes explored in the last 61 years comprises the following subjects: identity & human rights, immigration, government, media, health, international politics, Dalai Lama, nationhood, preservation of culture, resettlement, and a new generation of Tibetans.

Digitalisation On Automotive Supply Chain for Climate Competitiveness: A Systematic Bibliometric Analysis

The automotive industry, a cornerstone of global manufacturing, is undergoing a profound transformation driven by digitalization. This research paper explores the impact of digitalization on the automotive supply chain and its role in enhancing climate competitiveness. As the industry strives to meet stringent environmental standards and consumer demands for sustainability, leveraging digital technologies becomes imperative. We use R Studio software to perform bibliometric analysis in this study. Our initial repository for data came from the Scopus database. Following a keyword search and before applying the limited criteria, we were able to find 3202 papers. We then started integrating the limited criteria, which included the following: stream: Business Management & Accounting, source type: Journal, no author, duplicate titles, and language: English. After applying these criteria, we were able to find 935 papers. We selected citations, bibliographical data, abstracts and keywords, funding information, and other data before exporting our database from Scopus.

A bibliometric and visual analysis of research trends and hotspots of familial hypertrophic cardiomyopathy: A review.

Familial hypertrophic cardiomyopathy (FHCM) is an inherited cardiac disease caused by mutations of sarcomere proteins and can be the underlining substrate for major cardiovascular events. Early identification and diagnosis of FHCM are essential to reduce sudden cardiac death. So, this paper summarized the current knowledge on FHCM, and displayed the analysis via bibliometrics method. The relevant literature on FHCM were screened searched via the Web of Science Core Collection database from 2012 to 2022. The literatures were was summarized and analyzed via the bibliometrics method analyzed via CiteSpace and VOSviewer according to topic categories, distribution of spatiotemporal omics and authors, as well as references. Since 2012, there are 909 research articles and reviews related to FHCM. The number of publication for the past 10 years have shown that the development of FHCM research has been steady, with the largest amount of literature in 2012. The most published papers were from the United States, followed by the United Kingdom and Italy. The University of London (63 papers) was the institution that published the most research articles, followed by Harvard University (45 papers) and University College London (45 papers). Keywords formed 3 clusters, focused on the pathogenesis of FHCM, the diagnosis of FHCM, FHCM complications, respectively. The bibliometric analysis and visualization techniques employed herein highlight key trends and focal points in the field, predominantly centered around FHCM's pathogenesis, diagnostic approaches, and its complications. These insights are instrumental in steering future research directions in this area.

Optimization of municipal solid waste collection system: systematic review with bibliometric literature analysis

AbstractMunicipal solid waste management (MSWM) requires significant planning and objective definitions of each of its stages. Waste collection and transportation stages are of utmost importance, and they represent a significant cost of the process. In this context, a systematic study using bibliometric analysis was conducted, seeking to identify and understand the applied methodologies and tools, as well as which parameters and approaches are employed to optimize the solid urban waste collection system. The analysis portfolio features 12 publications, focusing on the optimization of municipal solid waste (MSW) collection systems, mostly with the aim of optimizing routes for transporting waste from the collection points to the final destination, with the goal of reducing the costs of this stage. Results highlight how these studies only consider as optimization criteria the reduction of the travelled distance and lack other dimensions (such as an environmental impact perspective). Some of the studies demonstrate the vital role of technology in optimizing the waste collection operation, from the use of geographic information systems (GIS) to using sensors or smart bins. Future research efforts should widen the scope of what is considered in optimizing the waste collection system.

A bibliometric analysis on the health behaviors related to mild cognitive impairment

BackgroundMild cognitive impairment (MCI) is commonly defined as a transitional subclinical state between normal aging and dementia. A growing body of research indicates that health behaviors may play a protective role against cognitive decline and could potentially slow down the progression from MCI to dementia. The aim of this study is to conduct a bibliometric analysis of literature focusing on health behaviors and MCI to summarize the factors and evidence regarding the influence of health behaviors on MCI.MethodsThe study performed a bibliometric analysis by retrieving publications from the Science Citation Index and Social Sciences Citation Index sub-databases within the Web of Science Core Collection. Utilizing VOSviewer and CiteSpace software, a total of 2,843 eligible articles underwent co-citation, co-keywords, and clustering analyses. This methodology aimed to investigate the current status, trends, major research questions, and potential future directions within the research domain.ResultsThe bibliometric analysis indicates that research on healthy behaviors in individuals with MCI originated in 2002 and experienced rapid growth in 2014, reflecting the increasing global interest in this area. The United States emerged as the primary contributor, accounting for more than one-third of the total scientific output with 982 articles. Journals that published the most articles on MCI-related health behaviors included “Journal of Alzheimer’s Disease,” “Neurobiology of Aging,” “Frontiers in Aging Neuroscience,” and other geriatrics-related journals. High-impact papers identified by VOSviewer predominantly cover concepts related to MCI, such as diagnostic criteria, assessment, and multifactorial interventions. Co-occurrence keyword analysis highlights five research hotspots in health behavior associated with MCI: exercise, diet, risk factors and preventive measures for dementia, cognitive decline-related biomarkers, and clinical trials.ConclusionThis study provides a comprehensive review of literature on health behavior in individuals with MCI, emphasizing influential documents and journals. It outlines research trends and key focal points, offering valuable insights for researchers to comprehend significant contributions and steer future studies.

Two decades of learning agility and an integrated framework: a review of literature and bibliometric analysis

Purpose Due to the extremely complicated and unpredictable outside world, using and unlocking the potential of learning agility (LA) has become a key part of making businesses more competitive, and there is a lot of new research being produced on this topic very quickly. Thus, this study aims to carry out a bibliometric analysis to systematically analyse the existing literature on LA and propose an integrated framework depicting various predictors, mediators and outcome variables covered in the LA research. Moreover, this study lays out a rich and detailed agenda for future research and enhances understanding of LA by suggesting future research questions. Design/methodology/approach This study applied bibliometric analysis using the Scopus database. This study applied bibliometric analysis and cluster analysis to examine the contributions of research constituents (authors, institutions, countries and journals) and their structural and thematic relationships (co-citation network and thematic trends). The most important insights were used to propose an integrated conceptual model. Findings Based on the results of the performance analysis, this study discovered that the USA is the most productive country in this research field, followed by Belgium, Australia, Korea and India. In addition, the findings highlight the most prominent journals, authors and countries contributing to LA, document citations and theories contributing to the field of LA. This study identifies four emerging future research themes (clarity of construct, identification of variables to be studied with LA, strategies enhancing LA and context of study) and proposes subsequent research questions using science mapping analysis. Practical implications A review of existing literature on LA provides a clear understanding of the current and future state of research on this topic. And, from a practical standpoint, this study highlights emergent clusters that will help practitioners build LA as a tactical reaction to the current volatile, uncertain, complex and ambiguous environment. Originality/value This study is relevant as it aims to systematically review articles on LA and proposes an integrated conceptual framework based on existing literature that will serve as a guide for existing and future research in this area.

Bibliometric analysis and evaluation of publications on non-Helicobacter pylori helicobacters from 1993 to 2023.

Aim: A bibliometric analysis and evaluation of research on non-Helicobacter pylori Helicobacter species (NHPHs) is essential to determining future research directions. Materials & methods: A comprehensive search was carried out using predetermined search terms within the Web of Science Core Collection (WoSCC) to gather publications spanning from 1993 to 2023. VOSviewer and Citespace were employed for data analysis and visualization. Results: 308 publications on NHPHs were included. Among these, gastric NHPHs received more publications and attention compared with enterohepatic NHPHs. Key findings included the identification of most productive countries, institutions, journals, authors, keywords, research trends and notable perspectives in the field. Conclusion: The article guides further research and clinical applications on NHPHs.

The evolution of Pemphigus publications: A bibliometric analysis with research trends and global productivity.

Despite an increase in global research on the subject of Pemphigus, which seriously affects patient health and quality of life, there is no bibliometric research on this subject in literature to date. The aim of this study was to conduct a holistic analysis of scientific articles published on Pemphigus, using bibliometric methods. Articles published on the subject of Pemphigus between 1980 and 2021 were downloaded from the web of science (WoS) database and analyzed using various statistical methods. To determine trend subjects, collaboration between countries, and the most effective studies with citation analyses, visual network maps were obtained with bibliometric analyses. A total of 3034 articles were analyzed. The 3 countries making the greatest contribution to literature were the USA (n:831, 27.3%), Japan (n:402, 13.2%), and Germany (n:221, 7.2%). The 3 most active institutions were Keio University (n:163, 5.3%), Kurume University (n:130, 4.2%) and Tel Aviv University (n:107, 3.5%). The 3 journals publishing the most articles were the British Journal of Dermatology (n: 88), Journal of the American Academy of Dermatology (n:171) and the Journal of Investigative Dermatology (n:143). The 3 leading journals according to the mean number of citations (NC) per article (citation count: CC) were the New England Journal of Medicine (CC:246), the Lancet (CC:143) and the Journal of Cell Biology (CC:133). The author with the most articles published was Hashimoto Takashi (n.168, 5.5%). As a result of cluster analysis, it was seen that 9 different main clusters had been studied on Pemphigus subjects to date (1: desmoglein, 2: paraneoplastic Pemphigus (PNP) - Pemphigus types-desmosome, 3: desmoglein 1 ve 3-autoimmunity, 4: treatment-rituximab, 5: acantholysis-apoptosis, 6: quality of life-remission-relapse, 7: autoantibodies, 8: epidemiology-mortality, 9: corticosteroids). The most commonly studied subjects were determined to be pemphigus vulgaris (PV), pemphigus foliaceus (PF), autoimmunity, rituximab, PNP, desmoglein (desmoglein3-desmoglein1), autoantibodies, acantholysis, autoantibody, treatment, autoimmune disease, desmosome, ELISA, and immunofluorescence. The primary trending topic was rituximab drug, which is used in the treatment of Pemphigus. The other most studied trend topics were azathioprine drug used in treatment, intravenous immunoglobulin treatment, quality of life, mortality rates, Pemphigus herpetiformis, and wound healing.

Research trends on acupuncture for neuropathic pain: A bibliometric analysis from 1979 to 2023.

Acupuncture has drawn increasing attention as a complementary and alternative therapy for neuropathic pain (NP). The present study aimed to summarize the current status and research trends on acupuncture for NP over the past several decades. The publications on acupuncture for NP in the database of Web of Science Core Collection from 1979 to 2023 were searched. VOSviewer (1.6.15) and CiteSpace software (5.5.R2) were applied to identify active authors, journals, countries and institutions, co-cited references and hot keywords. A total of 642 publications were finally included, and the quantitative trend of annual publications on acupuncture for NP have shown overall upward from 1979 to 2023. Peoples R China was the most productive and influential country, while Kyung Hee University from South Korea was both the first in publications and citations. Fang JQ ranked the first productive author and Han JS was the first 1 among the co-cited authors. The first productive journal was Evidence-based Complementary and Alternative Medicine, while the first co-cited journal was Pain. The high-frequency keywords were divided into 9 clusters, and the frontier topic focused on "Chronic pain". This present study visually showed the research status and trends of acupuncture for NP from 1979 to 2023 on the basis of bibliometric analysis, which may in some way help researcher discovery and explore some new research directions and ideas in the future.

Board leadership in global ventures: A bibliometric analysis

This study explores the relationship between administrative advice and international market entry modes. The board of directors has the authority to determine internationalization strategies for both large multinational corporations and small and medium-sized organizations. Existing theoretical frameworks dealing with internationalization provide a strong foundation for understanding the dynamics of entry modes and corporate governance. The study presents a framework consisting of four thematic elements: characteristics, capabilities, behavior, and composition of the advice. This framework is utilized to analyze the complexities of the decision-making processes of boards. Despite acknowledging its limitations, this study provides practical insights for business managers and contributes to the ongoing theoretical debate on this topic, highlighting the need for more comprehensive frameworks that consider psychological and cultural factors in the decision-making process of boards in the context of international business.

Research hotspots and trends of complementary and alternative therapy for neuropathic pain: A bibliometric analysis.

Neuropathic pain (NP) is a common type of pain in clinic. Due to the limited effect of drug treatment, many patients with NP are still troubled by this disease. In recent years, complementary and alternative therapy (CAT) has shown good efficacy in the treatment of NP. As the interest in CAT for NP continues to grow, we conducted a bibliometric study of publications on CAT treatment for NP. The aim of this study is to analyze the development overview, research hotspots and future trends in the field of CAT and NP through bibliometric methodology, so as to provide a reference for subsequent researchers. Publications on CAT in the treatment of NP from 2002 to 2022 were retrieved from the Web of Science Core Collection. Relevant countries, institutions, authors, journals, keywords, and references were analyzed bibliometrically using Microsoft Excel 2021, bibliometric platform, VOSviewer, and CiteSpace. A total of 898 articles from 46 countries were published in 324 journals, and they were contributed by 4455 authors from 1102 institutions. The most influential country and institution are China (n = 445) and Kyung Hee University (n = 63), respectively. Fang JQ (n = 27) and Evidence-Based Complementary and Alternative Medicine (n = 63) are the author and journal with the most publications in this field. The clinical efficacy, molecular biological mechanisms and safety of CAT for NP are currently hot directions. Low back pain, postherpetic neuralgia, acupuncture, and herbal are the hot topics in CAT and NP in recent years. This study reveals the current status and hotspots of CAT for NP. The study also indicates that the effectiveness and effect mechanism of acupuncture or herbs for treating emotional problems caused by low back pain or postherpetic neuralgia may be a trend for future research.

Islamic Fintech Research Worldwide: A Bibliometric Analysis

Islamic Fintech continues to grow as innovation in the field of technology accelerates human life. Although relatively new, research on Islamic Fintech continues to grow and has been quite attractive to researchers in recent years. Seeing this phenomenon, it is necessary to anticipate the increasing interest of academics in researching Islamic Fintech. This paper aims to facilitate researchers in finding out the development of Islamic Fintech research, find topics that can be developed, and know the main contributors and sources that shape research in the field of Islamic Fintech. This research analysis is a Bibliometric analysis with Biblioshiny and VOSviewer software, using metadata consisting of 98 Scopus-indexed data published in 10 years, namely 2013-2022. The results of the study found that the potential for developing research on the theme of Islamic Finance is huge, topics that can be developed for further research include "Crowdfunding" and "Crowdsourcing.” Meanwhile, Muslim-majority countries dominate Islamic Finance research, including with their authors and affiliations.

SYSTEMATIC LITERATURE REVIEW: POLITICAL PATRONAGE VERSUS MERIT SYSTEM ON LOCAL GOVERNMENT ANALYSIS VOSVIEWER

It is important to improve the public sector with recruitment rules that aim to improve public services by minimising political interests and patronage practices. The purpose of this study is to examine the development of the application of the merit system in the prevention of patronage practices in local government. Bibliometric analysis using VOSViewer. The literature review in this study provides an overview of the improvement of the public sector from the perspective of the merit system, taking articles in the period 2013-2023. The results obtained in this study are the prevention of patronage practices with the merit system in local government administration successfully implemented in Indonesia, namely in the cities of Medan, Deli Serdang and DIY, while in other countries it was successfully implemented in the African state of Nigeria, the merit system is used to prevent political patronage in the public sector by ensuring the acceptance of competent employee candidates, and reducing the influence of political patronage that previously hindered the development of public services and justice.

A commentary on 'Could nerve transplantation be the future of this field: a bibliometric analysis about lumbosacral plexus injury' (Int J Surg 2024 Mar).

A commentary on 'Could nerve transplantation be the future of this field: a bibliometric analysis about lumbosacral plexus injury' (Int J Surg 2024 Mar).

The evolution of net zero emissions research: A bibliometric investigation

This research presents a comprehensive examination of the advancements in the field of net zero emissions during the period from 1991 to August 2023. The study employs a content and descriptive analysis methodology, with a primary focus on bibliometric analysis. Extensive datasets are scrutinized, and various quantitative variables, including temporal patterns, prolific researchers, productive countries, and citation counts, are analyzed within a comprehensive collection of research papers on net zero. The statistical analysis assesses outcomes from diverse institutions and individuals, taking into account temporal and geographical contexts while exploring connections between publications. Statistical methods, such as the TC index and citation rates, are utilized to quantitatively evaluate the influence of researchers and academic journals. Patterns of publication are examined to identify noteworthy developments and research gaps. Data from the reputable Web of Science Core Collection database is sourced, and systematic searches are conducted to minimize potential biases. The collated information comprises author details, institutional affiliations, geographical locations, source journals, annual publication rates, citation counts, research areas, funding sources, and H-index. The study is conducted by two independent investigators with any discrepancies resolved through collaborative discussions. This research offers valuable insights into the current state of net zero research, trends, prominent contributors, and global collaborations, thereby enhancing the comprehension of this critical domain.

The top 50 most-cited articles about COVID-19 and the complications of COVID-19: A bibliometric analysis

Background This bibliometric analysis examines the top 50 most-cited articles on COVID-19 complications, offering insights into the multifaceted impact of the virus. Since its emergence in Wuhan in December 2019, COVID-19 has evolved into a global health crisis, with over 770 million confirmed cases and 6.9 million deaths as of September 2023. Initially recognized as a respiratory illness causing pneumonia and ARDS, its diverse complications extend to cardiovascular, gastrointestinal, renal, hematological, neurological, endocrinological, ophthalmological, hepatobiliary, and dermatological systems. Methods Identifying the top 50 articles from a pool of 5940 in Scopus, the analysis spans November 2019 to July 2021, employing terms related to COVID-19 and complications. Rigorous review criteria excluded non-relevant studies, basic science research, and animal models. The authors independently reviewed articles, considering factors like title, citations, publication year, journal, impact factor, authors, study details, and patient demographics. Results The focus is primarily on 2020 publications (96%), with all articles being open access. Leading journals include The Lancet, NEJM, and JAMA, with prominent contributions from Internal Medicine (46.9%) and Pulmonary Medicine (14.5%). China played a major role (34.9%), followed by France and Belgium. Clinical features were the primary study topic (68%), often utilizing retrospective designs (24%). Among 22,477 patients analyzed, 54.8% were male, with the most common age group being 26-65 years (63.2%). Complications of COVID-19 affected 13.9% of patients, with a recovery rate of 57.8%. Conclusion Analyzing these top-cited articles offers clinicians and researchers a comprehensive, timely understanding of influential COVID-19 literature. This approach uncovers attributes contributing to high citations and provides authors with valuable insights for crafting impactful research. As a strategic tool, this analysis facilitates staying updated and making meaningful contributions to the dynamic field of COVID-19 research.