Bibliometric Analysis Research Articles

Make data flow: Understanding the (re)usability of research data

Opening data and making datasets reusable is an extremely important and urgent need, especially as we move towards more data-driven studies worldwide. Various stakeholders are involved in the life cycle of data (re)use, including data providers/sharers, data (re)users, data managers/curators, and funding agencies. In response to the divergent demands of these stakeholders, data repositories have been established to bridge their needs and facilitate the cycle of data sharing and (re)use. However, recent studies have shown that data is being shared and (re)used through open data repositories at much lower levels than expected. This underscores a fundamental and often overlooked challenge in research data management, inviting a deeper and more comparative examination of the perspectives of various stakeholders on data (re)use. Using a mixed-method approach that includes metadata analysis, interview-based qualitative studies, and quantitative bibliometric analysis, this project first delves into the facilitating and inhibiting factors affecting a dataset's potential for (re)use, considering the perspectives of both data (re)users and data curators. It will then identify and elucidate the disparities between data (re)users and data curators, proposing suggestions for future data curation efforts. The findings will prompt data curators and data repositories to re-examine their current metadata frameworks and data curation practices, aligning them more closely with the actual needs of data (re)users. Moreover, this effort will make the flow of research data moves more smoothly within our academic communities, and contribute to the building of a more inclusive, equitable, open, and user-friendly research infrastructure.

Bibliometric Analysis of Perceived Employability: Review and Research Agenda

The changing nature of employment relations between individuals and organisations has increased the role of individuals in maintaining their careers. Today’s era is characterised by ‘modern and boundary less’ careers, indicating the need for an in-depth analysis of perceived employability. For a long time, this multidisciplinary concept has captured the attention of scholars. However, holistic retrospection of this research is missing to date. Under this gap, this study aims to comprehensively analyse the literature on perceived employability through bibliometric tools. Therefore, a contextualised systematic literature review is presented in this study using citation analyses, co-citation analyses and bibliographic coupling. Relying upon the Scopus database, bibliometric techniques are used to map thematic and intellectual structures latent in 356 articles published on perceived employability. The top authors, countries, journals and major themes are identified, followed by bibliographic network-based content analysis. Five significant clusters identified by thematic analyses are extensively reviewed. Finally, the study revealed key research gaps that could guide future research. This study contributes by providing thematic clusters latent in the literature on perceived employability in combination with an extensive review.

Integration of Circular Economy and Urban Metabolism for a Resilient Waste-Based Sustainable Urban Environment

An unsustainable rate of resource production and consumption is evident in urban environments. The absence of innovative approaches in conjunction with the exponential urbanization and expansion of the global population will inevitably result in substantial environmental consequences. There are two emerging alternatives: circular economy (CE) and urban metabolism (UM). The integration of these principles into novel methodology casts doubt on the linear model of contemporary economic and urban systems, which includes extraction, production, utilization, and disposal. In the development of a distinctive urban framework known as circular urban metabolism, the current study has illustrated the application of these principles. We design this study to motivate urban planners and decision-makers to investigate, develop, and supervise ecologically sustainable cities. Scholars from a variety of academic disciplines, intrigued by the intricacies of urban planning, design, and administration, can foster interdisciplinary collaboration in the circular urban metabolism (CUM) region. To address the research question, we implemented a bibliometric analysis, which involved the examination of 627 pertinent research papers, utilizing the R (R 3.6.0+) statistical programming language. The results emphasize the fundamental characteristics and significance of CUM in the management of refuse. In addition, the findings underscore the importance of creating a novel framework that incorporates the principles of urban political ecology, CUM, sustainability, and the novel dimension of waste metabolism. It is the goal of this framework to emphasize the significance of recycling in the informal sector as a waste management strategy in low- and medium-income countries (LMICs).

The Integration of Land Restoration and Biodiversity Conservation Practices in Sustainable Food Systems of Africa: A Systematic Review

Land degradation poses a significant global challenge, adversely affecting soil quality and diminishing the productivity of arable land, which, in turn, impacts food production and ecosystem services. This degradation manifests in various forms, including soil compaction, salinity, nutrient depletion, loss of biodiversity, and contamination, ultimately rendering soil unproductive and exacerbating climate change. Given the challenges arising from conventional farming practices and climate change, there is an urgent necessity to develop agricultural systems that not only enhance agronomic efficiency but also improve environmental performance. This study focuses on addressing food security in Africa by investigating the role of land restoration and biodiversity in sustainable food systems through a comprehensive bibliometric analysis for documents between 2010 to 2023, identifying 64 relevant documents. The analysis reveals insights into the most-cited documents and thematic evolution, underscoring the significant contributions from Ethiopia and advocating for collaborative efforts among African nations. Key themes identified include “climate change”, “food security”, “biodiversity conservation”, and “agroecosystems”, all highlighting the importance of sustainable agricultural practices. The study anticipates a continued prioritization of agroecosystems, smart agriculture, and biodiversity conservation to tackle food security challenges in the face of climate change. Collaboration, investment in research, and practical initiatives emerge as essential components for achieving sustainable food security and mitigating climate change impacts in Africa. This research provides valuable insights into the current landscape and future trends regarding the contributions of land restoration and biodiversity to food systems in Africa, emphasizing the critical need for concerted efforts to address these pressing issues.

Vitamin D: A key player in COVID-19 immunity and lessons from the pandemic to combat immune-evasive variants.

As of the 7th of July 2024, 775,754,322 confirmed cases of COVID-19, including 7,053,902 deaths worldwide, had been reported to the WHO (World Health Organization). Nevertheless, untill the 15th of July 2024, a total of 13,578,710,228 vaccine doses had been administered, with almost no country spared from COVID-19 attacks. The pathophysiology of this virus is complicated, and several symptoms require a deep understanding of the actual mechanisms. It is unclear why some patients develop severe symptoms while others do not, although literature suggests a role for vitamin D. Vitamin D plays a crucial role in the infection or in ameliorating the severity of symptoms. The mechanism of action of vitamin D and vitamin D deficiency (VDD) is well understood. VDD is associated with increased hospitalization of severely ill patients and increased levels of COVID-19-caused mortality. Recent studies suggest that vitamin D levels and genetic variations in the vitamin D receptor (VDR) gene significantly impact the severity and outcomes of COVID-19, especially in the infections caused by Delta and Omicron variants. Furthermore, VDD causes immune system dysregulation upon infection with SARS-CoV-2, indicating that vitamin D sufficiency is crucial in fighting against COVID-19 infection. The therapeutic effect of vitamin D raises interest in its potential role as a prophylactic and treatment adjunct. We evaluate the immunomodulatory effects of vitamin D and its ability to enhance the efficacy of new antiviral drugs like molnupiravir and paxlovid against SARS-CoV-2. This review discusses the role of vitamin D sufficiency and VDD in COVID-19 initiation and progression, emphasizing the molecular mechanisms by which vitamin D exerts its actions as a proactive step for the next pandemic. However, there is still no clear evidence of vitamin D's impact on prevention and treatment, leading to contradictory findings. Therefore, large-scale randomized trials are required to reach a definitive conclusion. A bibliometric analysis of publications related to vitamin D, immunity, and COVID-19 revealed a significant increase in research activity in this area, particularly in 2020-2024, underscoring the growing recognition of vitamin D's potential role in the context of the pandemic.

Global Trends and Research Collaborations on Food and Beverages Warning Labels: A Bibliometric Analysis

Background: Non-communicable diseases (NCDs) represent a global health challenge, accounting for 74% of deaths worldwide. One of the recommended interventions to reduce the risk of NCDs is the implementation of warning labels (WLs) on food products to alert consumers about high levels of undesirable nutrients, such as sugar or saturated fats. We aimed to conduct a bibliometric analysis of scientific literature related to WL policies in food and beverages to evaluate global trends and collaborations. Methods: A bibliometric analysis was performed using the Web of Science Core Collection (WoSCC). Articles published between 1998 and 2023 were retrieved using the search terms “warning labels” AND “food” OR “beverage”. Bibliometric indicators, including publication counts, citations, collaborations, and thematic trends, were analyzed using the Bibliometrix package in R and VOSviewer. Results: We included 255 articles on WLs. Scientific production increased markedly from 2018 onwards, with over 30 articles published annually from 2018 to 2023. The most cited article, by Taillie et al., focused on the impact of Chile’s WL policies. The United States had the largest scientific production, followed by Brazil and Chile. Nutrients was the journal with the most publications on this topic. Conclusions: The growth in WL-related research, particularly in Latin America, reflects the increasing implementation of these policies. These results underscore key collaborations and evolving research themes, from food labeling to broader public health impacts, emphasizing the need for continued evaluation of WL effectiveness.

Intellectual landscape of scholarly work on 21st century skills: A bibliometric and science mapping analysis

A quick search on Google Scholar for the exact phrase ‘21st century skills’ resulted in three thousand plus results. More than two-third of these are dated within the last decade, indicating growing attention to the topic in the academia. The purpose of the current study is to investigate existing literature on 21st century skills by employing techniques of bibliometric and science mapping analysis to provide a helicopter view of scholarly work on 21st century skills. The search was conducted on SCOPUS database during 2021 using the keyword ‘21st century skills’ which produced 1644 results. Further refinements were made using publication year, document type and language reducing the sample size to 1281 documents. Data were analysed employing various bibliometric indicators such as number of publications, contributing authors, institutions and countries, citation, co-citation, and keywords. The results indicated an exponential growth in the number scholarly publication on the topic since 2010. Similarly, a positive trend in average citations was also observed in recent years. USA was the biggest contributor to the number of publications, followed by Indonesia, and Malaysia respectively. With respect to author collaboration, Nussbaum, M. was found the highest collaborator, followed by Griffin P., and Sharples M. while among the institutions, University of Melbourne was at the top. Analysis of the keywords revealed that, specific 21st century skills, learning tools and processes, technological advancement, and education and training are amongst the most common research themes. Findings of the current study provide insights into future research trends on the topic of 21st century skills.

Water resources management: a bibliometric analysis and future research directions

Water resources management: a bibliometric analysis and future research directions

Phishing and the Human Factor: Insights from a Bibliometric Analysis

Academic research on the human element in phishing attacks is essential for developing effective prevention and detection strategies and guiding policymakers to protect individuals and organizations from cyber threats. This bibliometric study offers a comprehensive overview of international research on phishing and human factors from 2006 to 2024. Analysing 308 articles from the Web of Science database, a significant increase in publications since 2015 was identified, highlighting the growing importance of this field. The study revealed influential authors such as Vishwanath and Rao, leading journals like Computers & Security, and key contributing institutions including Carnegie Mellon University. The analysis uncovered strong collaborations between institutions and countries, with the USA being the most prolific and collaborative. Emerging research themes focus on psychological factors influencing phishing susceptibility, user-centric security measures, and the integration of technological solutions with human behaviour insights. The findings highlight the need for increased collaboration between academia and non-academic organizations and the exploration of industry-specific challenges. These insights offer valuable guidance for researchers, practitioners, and policymakers to advance their understanding of phishing attacks, human factors, and resource allocation in this critical aspect of digitalisation, which continues to have significant impacts across business and society at large.

Bibliometric Analysis and Research Trends on Microplastic Pollution in the Soil and Terrestrial Ecosystems

Environmental pollution from microplastics (MPs), an anthropogenically mediated menace to the biosphere, is a global concern. This research conducted a bibliometric analysis of MPs in soil and terrestrial ecosystems using R software and biblioshiny to analyze descriptive statistics, author contributions, documents, and conceptual structures. The Scopus database was selected, and various keywords optimized the search. An analysis of research trends divided the timeline into three periods: period I (2012–2018), period II (2019–2021), and period III (2022). Results showed Wang J. as the author with the highest h-index, while Science of the Total Environment had an h-index of 43. In period I, research focused on MPs and plastic pollution, raising questions about their impacts on terrestrial ecosystems. Research found that MPs negatively affected soil organisms by decreasing growth rates and causing weight loss. In period II, research diversified, exploring interactions between MPs and heavy metals, bioaccumulation, phytotoxicity, soil pollution, and gut microbiota. Research revealed that MPs could influence heavy metal uptake by plants and affect bacterial community structures in soil. In period III, research emphasized oxidative stress, a common ecotoxicity response in plants and animals. MPs induced oxidative stress, leading to reactive oxygen species (ROS) buildup. Polyethylene MPs were more toxic to plant seedlings than polystyrene and polypropylene, causing significant oxidative stress. Similarly, oxidative stress impacts on soil organisms were highlighted when exposed to MPs and pesticides. Research in this area is expected to continue growing, aiding in delineating distinct research paths, particularly focusing on oxidative stress, bioaccumulation, and heavy metals.

A review of the knowledge structure and trends in research on the interlinkages between the rule of law and environmental sustainability

AbstractThe interplay between nature and human activities is important for both human well‐being and the health of our planet. The rule of law is central to maintaining harmony between environmental needs and human endeavors. Since the early 1990s, particularly after the Earth Summit in 1992, there has been an increased interest in the relationship between environmental sustainability and legal frameworks. This has led to a significant expansion in the field, encompassing a wide array of research. Despite the field's growth, there is still a lack of review papers that explore its knowledge structure and evolution. This study aims to conduct a comprehensive bibliometric analysis of the literature by employing the Visualization of Similarities (VOS) viewer software. We identify key thematic areas within the field, highlight influential authors and journals, and specify major contributing countries and institutions. The findings show that the initial focus was on limited themes, which later gave way to an acknowledgment of the multidimensional nature of the subject. Certain themes, such as environmental emissions and governance, retain prominence. Among the focal themes, sustainability, climate change, and democracy are particularly influential in shaping the field's trajectory. Despite this evolution, certain aspects of both concepts, such as waste and water management, fundamental rights and justice system, and the importance of socio‐economic factors, remain underrepresented. This study offers valuable insights into the linkage between the rule of law and environmental sustainability themes and the associated themes.

Comment on “Bibliometric analysis of dendritic cell-based vaccines over the past 15 years”

Comment on “Bibliometric analysis of dendritic cell-based vaccines over the past 15 years”

A systematic literature review of life cycle sustainability assessment of mass timber in the construction industry toward circular economy

AbstractLife cycle analysis has been used to evaluate the environmental impacts and economic costs of a range of engineered timber structural materials as well as other materials such as steel and concrete over the last two decades. This study presents a bibliometric analysis and systematic critical review by investigating the life cycle sustainability assessment (LCSA) of engineered timber products. LCSA is comprised of three main pillars namely, environment, cost, and social impact. The study compares alternative engineering wood products used in building structures such as columns, beams and wall surfaces. The geographical distribution, main sources of research, co-occurrence of keywords were analyzed for 93 peer-reviewed articles and conferences. The United States was the most productive country, contributing almost 23 documents. Australia was next with 12 publications. Most studies compared the LCA and LCC of alternative Mass timber products and concrete or steel. Most studies evaluated cross laminated timber (62%), followed by glued laminated timber (17%), and laminated veneer lumber (9%). A comparison of the economic and environmental aspects indicated that the social aspect are less considered. The review showed that the global warming potential of manufactring1 M3 of cross laminated timber is about 155.6–158.6 kg CO2eq. The majority of the publications reviewed focused on LCA whilst others focussed on the LCC of Mass timber. No research on social life cycle assessment has been conducted as yet. A framework is suggested for future research to identify the best alternative for engineering wood.

Ethnomycology and Uses of Macrofungi in Brazil: a Bibliometric Review From 2014 to 2024

Objective: The objective of the study was to present an overview of ethnomycological publications in Brazil on the use of macrofungal species based on the analysis of their evolution between the years 2014 to July 2024. Theoretical Framework: Ethnomycology is research field that goes beyond traditional and scientific knowledge and has the purpose of documenting the customs and the material and spiritual culture of different communities with respect to fungi. Method: We conducted a bibliometric analysis with data obtained from four databases: Scielo, Google Scholar, ScienceDirect and PubMed. The Prisma 2020 method of meta-analyses was used. Results and Discussion: The central sub-themes of the retrieved studies were related to Brazilian ethnomycology, perception of medicinal and/or edible use of macrofungi in Brazil, as well ethnomicological perception of macrofungi in schools in Brazil. Research Implications: The region with the highest number of publications was the Northeast (46.6%), with six studies, five of them in the state of Piauí, followed by the North, with four studies. The sub-theme "perception and uses of macrofungi" stood out (78%). Originality/Value: The studies focused on rural and urban communities in Brazil. We conclude that more efforts are needed to disseminate Ethnomycology and the gaps between humans and fungi, especially considering the lack of studies in some states of Brazil.

Mapping the evolution and impact of ketogenic diet research on diabetes management: a comprehensive bibliometric analysis from 2005 to 2024.

The ketogenic diet (KD) has been explored for diabetes management; however, a quantitative synthesis of its specific effects on diabetes has not yet been conducted. This study aims to examine the current status and research hotspots of KD in diabetes management from 2005 to 2024, providing a reference for future research. We retrieved articles published between 2005 and 2024 from the Web of Science database and analyzed them using R software, VOSviewer, and CiteSpace. This study includes 432 relevant publications. From 2005 to 2024, the volume of literature in this field has shown a steady upward trend, with a notable increase from 2017 to 2021, and a slight decline observed from 2021 to 2023. The United States is the leading country in terms of the number of publications, followed by China, Australia, and Canada. The United States not only leads in publication volume but also maintains a broader international collaboration network. Nutrients and the American Journal of Clinical Nutrition are the most frequently published and cited journals. Current research hotspots primarily focus on the impact of KD on blood glucose control, insulin resistance, and lipid metabolism in diabetic patients. Mechanistic studies on KD in diabetes management concentrate on aspects such as the "regulation of genes by β-hydroxybutyrate," "anti-inflammatory effects," and "oxidative stress." The role of the gut microbiome is also emerging as an important research area. Currently, exploring the application of KD in managing different age groups and types of diabetes has become a significant research trend. As an emerging dietary intervention, KD is gradually attracting widespread attention from researchers around the world and is expected to become a major research focus in the future for diabetes management and control. This paper provides a systematic review and analysis of the current research status and hotspots of KD in diabetes management, offering important references and insights for future research in related fields.

A 20-year analysis of gender trends in oncology authorship in the Cochrane database of systematic reviews.

The objective of this study was to evaluate global longitudinal publication trends in oncology in the Cochrane Database of Systematic Reviews (CDSR) from 2001-2020. Retrospective bibliometric analysis. The primary outcome measures were the numbers and percentages of women as first, last, and corresponding author across all CDSR oncology publications. Additional outcomes included authorship differences between countries and percentages of women authors over time compared using the Cochran-Armitage trend test. In total, 548 articles were analyzed. Women were first authors in 52.26% (n=277) and corresponding authors in 50.75% (n=272), respectively. Women represented only 39.4% (n=210) of last authors, significantly less frequent than male counterparts (p < 0.001). The percentage of women last and corresponding authors has increased significantly in the past 20 years (p < 0.05). Countries such as the Netherlands and Australia consistently showed equitable representation in first, corresponding, and last authorship, while other countries such as Italy and China had uniformly low rates of female authorship. Our results highlight patterns of gender inequity in oncology publication authorship in the CDSR from 2001-2020 at a global level. Notably, women were less likely to serve in the last author position which, independent of assigned corresponding authorship, is generally assumed in academic oncology to designate the leader of a published study. Substantive efforts to correct this disparity are needed to achieve gender parity in publicly perceived leadership in oncology publications.

Bibliometric analysis of stone column research trends: A Web of Science perspective

Abstract Stone columns have garnered significant interest in geotechnical engineering as an effective ground improvement technique for enhancing the load-bearing capacity and mitigating settlement issues in soft soils. This study presents a comprehensive bibliometric analysis of scholarly literature on stone columns, utilizing data from the Web of Science database spanning from 1975 to 2023. The analysis aims to provide insights into publication trends, influential journals, key research institutions and authors, geographical distributions, and emerging themes in this domain. Through a systematic data curation process, 505 relevant publications were analyzed using Excel and VOSviewer software. The findings reveal a notable emphasis on geosynthetic encasements, load-settlement behavior, and soft soil reinforcement, with China being a major contributor. Over the past 48 years, the research has evolved from static loading to dynamic loading, sustainable structures, and artificial intelligence applications, as evidenced by the highly cited publications. This study maps the development, current state, and potential future directions of stone column research, serving as a valuable resource for researchers and practitioners in geotechnical engineering.

Navigating Global Research Trends on Seafoods-Related Foodborne Diseases: A Decadal Bibliometric Analysis

Ensuring seafood safety has become a critical area of focus due to its strong association with foodborne diseases. Despite the critical nature of this field, an in-depth understanding of global research trends in this field remains limited. Our study conducted an extensive bibliometric analysis to track the evolution and thematic focus of research on seafood safety from 2013 to 2023. Utilizing Scopus for publication and citation data, along with VOSviewer for visualizing keyword networks, this study highlights key developments and scholarly efforts aimed at mitigating risks associated with seafoods consumption. The analysis pinpoints the United States, China, the United Kingdom, France, South Korea and Malaysia as leading contributors. Their extensive research outputs and collaborations have markedly shaped the field's evolution. The overall positive trajectory in research volume experienced a minor setback in 2022, suggesting a complex and dynamic research landscape. "Food Control" is identified as a principal journal for the dissemination of research works, anchoring a dynamic co-citation network that fosters extensive international dialogue. We categorize seven principal research clusters: epidemiology, molecular detections, microbial resistance, bacteriophage applications, toxin detection methodologies, predictive modelling and biofilm studies. These clusters encompass the scopes and the breadth of current investigations. This decade-long review highlights the necessity for cohesive global research strategies to enhance the knowledge and control of foodborne pathogens in seafoods. This strategy is critical for improving food safety measures and safeguarding public health globally.

Aggression in psychiatry: a bibliometric analysis

BackgroundAggression is a common problem in psychiatric clinics, and many studies have been conducted on the issue over the years. This study bibliometrically examines the characteristics and trends of aggression studies in psychiatry, such as the branches, publication years, types, publishers, and impact factors, and compares the focus areas of psychiatry and psychiatric nursing on aggression, to guide future research and readers on this topic. Bibliometric analysis was performed with network metrics, citation analysis, co-authorship analysis, science mapping, and network visualization techniques using WoS analysis reports and the VOSviewer program with data obtained from the Web of Science database on January 11, 2024.ResultsMost studies on aggression in psychiatry were published in 2019 as English articles. Then, 3.37% of these studies are in psychiatric nursing, mainly from Australia. In contrast, most psychiatric studies are from the USA. Psychiatry studies focus on causes, types, and relationships with psychiatric disorders, while psychiatric nursing studies emphasize aggressive attitudes, risk assessment, and aggression management.ConclusionsIt appears that studies on aggression continue to remain current in the literature and will continue to do so, considering that aggression is an ongoing clinical problem worldwide. Despite this, studies on assessing and managing the risk of aggression are still lacking. Future studies should prioritize the management of aggression. While the study showed the presence of multidisciplinary and international collaborations, it is recommended that these collaborations be further expanded. Findings may inform researchers’ keyword and journal choices.

Research on therapeutic clinical trials including immunotherapy in triple-negative breast cancer: a bibliometric analysis.

Breast cancer, particularly triple-negative (TNBC), is a leading malignancy with aggressive traits and high metastasis rates. Clinical trial is an important tool for optimizing therapeutic strategies in the evaluation of the safety and efficacy for TNBC. Our bibliometric study of TNBC clinical trials aims to assess therapeutic strategies, identify trends, and explore advancements in treatment. We focus on mapping knowledge development, including key research entities and topics, and analyzing research trends and emerging methods. This analysis intends to inform future research, especially in personalized and precision medicine for TNBC. We selected publications on clinical trials for the treatment of TNBC from 1997 to 2024 in the Web of Science Core Collection (WoSCC). After an initial screening, we downloaded key data including titles, publication years, authors, countries, institutional affiliations, journals, keywords, and abstracts, and saved them in BibTex format. We then conducted a bibliometric analysis using Bibliometrix in R and VOSviewer to illustrate the prospects, highlights, and trends of TNBC treatment options. Furthermore, to emphasize the hot topics in TNBC treatment strategies, we performed a bibliometric analysis of immunotherapy using the same approach. 1907 publications were included, most of which were from China, Italy, and the United States. The number of annual publications has increased dramatically since 2010. The focus of TNBC clinical trial research has shifted from understanding the biology, such as breast cancer subtyping and genotyping, to novel therapeutic approaches. The major advancement in clinical trials is the switch from late-stage palliative treatment to early preoperative neoadjuvant therapy, as more TNBC cases are discovered at an early stage. Immunotherapy is also highlighted with additional alternatives for advanced or metastasized TNBC, such as targeted inhibitors with unusual mutation rates and antibody drug conjugates (ADC). This investigation made it apparent how immunotherapy has recently made major advancements in TNBC treatment plans and how ADCs, or targeted therapies, are currently popular for TNBC. By identifying significant papers, comprehending trending topics, and collaborating across multiple disciplines, this study may accelerate research on TNBC therapy options.