Benzimidazole Units Research Articles

A novel fluorescent probe based on naphthimide for detecting Zn2+ and its application in plant imaging and cell imaging

The fluorescent probe NXZ was synthesized by introducing –OH at position 1, 8-naphthalimide 4-position and benzimidazole unit at 3-position. The Stokes shift (λem − λex) of NXZ can up to 148 nm, when Zn2+ was added to the probe solution, NXZ can quickly form the complex NXZ-Zn2+ with Zn2+ in a ratio of 1: 1 within 55 s, and then quench the fluorescence intensity by 4.4 times. The complexation constant of NXZ and Zn2+ was 1.2 × 104 M−1, and the detection limit for Zn2+ was 40.3 nM, which is much lower than the maximum Zn2+ content (76 µM) stipulated in the World Health Organization (WHO). Exploring the practical application of the probe NXZ found that NXZ can be used for the quantitative detection of Zn2+ in actual water samples and qualitatively detect Zn2+ in bean sprouts samples and Hela cells. In addition, NXZ can also be made into Zn2+ test paper.

Enhanced Catalytic Activity of Binuclear Oxidovanadium(IV) Bisbenzimidazole Linked Porphyrin Dimer for the Generation of Biologically Active 3,4-Dihydropyrimidinones and Their Corresponding Thiones.

Binuclear vanadyl(IV) porphyrin (V2BP), where two vanadium(IV) porphyrin macrocycles are linked through benzimidazole units at the β-positions, has been prepared and characterized with various techniques, such as UV-vis, Fourier transform-infrared, electron paramagnetic resonance, cyclic voltammetry, density functional transform calculations, and mass spectrometry. V2BP exhibits a red shift (Δλmax = 10 nm) in the Soret band as compared with unsubstituted parent vanadyl(IV) meso-tetraphenylporphyrin (VP). The synthesized binuclear vanadyl(IV) porphyrin (V2BP) has further been studied as a catalyst to explore a single-pot multicomponent Biginelli reaction producing biologically active 3,4-dihydropyrimidin-2-(1H)-one (DHPM)-based biomolecules and the corresponding thiones under solvent-free conditions and its catalytic activity has been compared with vanadyl(IV) meso-tetraphenylporphyrin (VP). Several reaction conditions, such as the amount of catalyst, time, solvent, and temperature, have been optimized to obtain the maximum yield of DHPMs or thiones. The synthesized β-functionalized V2BP porphyrin dimer manifests much higher conversion (84-95% yield) of DHPMs or the corresponding thiones under the optimized reaction conditions with high TON (4454-5037) and TOF (1113-1259 h-1) values for the one-pot multicomponent Biginelli reaction as compared to the literature. The catalyst exhibited excellent recyclability up to 10 cycles.

Mechanistic Basis of the Cu(OAc)2 Catalyzed Azide-Ynamine (3 + 2) Cycloaddition Reaction.

The Cu-catalyzed azide-alkyne cycloaddition (CuAAC) reaction is used as a ligation tool throughout chemical and biological sciences. Despite the pervasiveness of CuAAC, there is a need to develop more efficient methods to form 1,4-triazole ligated products with low loadings of Cu. In this paper, we disclose a mechanistic model for the ynamine-azide (3 + 2) cycloadditions catalyzed by copper(II) acetate. Using multinuclear nuclear magnetic resonance spectroscopy, electron paramagnetic resonance spectroscopy, and high-performance liquid chromatography analyses, a dual catalytic cycle is identified. First, the formation of a diyne species via Glaser-Hay coupling of a terminal ynamine forms a Cu(I) species competent to catalyze an ynamine-azide (3 + 2) cycloaddition. Second, the benzimidazole unit of the ynamine structure has multiple roles: assisting C-H activation, Cu coordination, and the formation of a postreaction resting state Cu complex after completion of the (3 + 2) cycloaddition. Finally, reactivation of the Cu resting state complex is shown by the addition of isotopically labeled ynamine and azide substrates to form a labeled 1,4-triazole product. This work provides a mechanistic basis for the use of mixed valency binuclear catalytic Cu species in conjunction with Cu-coordinating alkynes to afford superior reactivity in CuAAC reactions. Additionally, these data show how the CuAAC reaction kinetics can be modulated by changes to the alkyne substrate, which then has a predictable effect on the reaction mechanism.

Synthesis and Photophysical Characterizations of Benzimidazole Functionalized BODIPY Dyes.

Herein, a series of new BODIPY dyes substituted by 2-phenyl benzimidazole units at the meso (C8) position including methyl/ethyl, phenyl, or p-methoxyphenyl moieties at the distal and proximal positions of the BODIPY core have been successfully synthesized and their photophysical characteristics were analyzed. Experimentally investigating absorption and fluorescence profiles in the THF media was followed by density functional theory (DFT) calculations to clarify photophysical features. Theoretical analyses have revealed that upon excitation, both electrons and holes are confined solely within the BODIPY core. The energy levels of the frontier molecular orbitals converge depending on the presence of the phenyl and p-methoxyphenyl substituents. The orbital distributions of both electron and hole were in the -3 and -5 positions, which demonstrates a continuous conjugation with the BODIPY core at these sites. However, the electron density present on the phenyl rings located at the -1, -7, and -8 (meso) positions was found to be negligible. The benzimidazole-BODIPYs exhibited photodynamic activity (Φ∆) ranging from ~ 7% to ~ 11%, determined by a comparative method. Moreover, the compounds have shown to maintain their stability thermally in a non-reactive/inert environment up to temperatures surpassing 300°C, exhibiting primarily a two-phase decomposition process. These compounds have the potential to function as antibacterial and anti-biofilm agents when used in concentrations ranging from 0.5 to 2.0mg/mL. The results provide a basis for evaluating heterocyclic benzimidazole units on photophysical processes containing BODIPY chromophores.

A benzimidazole-appended double-armed salamo type fluorescence and colorimetric bifunctional sensor for identification of MnO4− and its applications in actual water samples

The symmetrically double-armed salamo type fluorescent sensor BMS, incorporating benzimidazole units, was designed and synthesized. Showcasing remarkable specificity and responsiveness to MnO4- within a DMSO:H2O (V/V = 9:1, pH = 7.2) Tris-HCl buffer medium, it enabled dual-channel detection of MnO4- through fluorescent and colorimetric changes. Critical experimental parameters, including detection and quantification thresholds (LOD and LOQ) along with binding affinity constants (Ka), were calculated using the Origin software. A rational interaction mechanism between BMS and MnO4- was deduced, based on fluorescence titration, Electrospray Ionization Mass Spectrometry (ESI-MS), Ultraviolet–Visible Spectroscopy (UV–Vis), Infrared Spectroscopy (IR), Stern-Volmer plots, and Density Functional Theory (DFT) computations. Additionally, the sensor BMS was applied to monitor MnO4- in real water samples. Advancing its practical utility, BMS was fabricated into test strips for the selective detecting of MnO4-.

Electrocatalytic urea synthesis from CO2 and nitrate co-reduction on natural vitamin B12 coupled carbon nanotubes

The synthesis of urea from CO2 and nitrate co-electrolysis is highly attractive for the sustainable production of nitrogen-containing fertilizers such as urea. However, this process requires electrocatalysts that are not only highly active but also selective. In this study, we present a remarkable approach wherein Vitamin B12 is immobilized on the surface of carbon nanotubes to catalyze the co-electroreduction to urea under ambient conditions. This unique hybrid system, incorporating a naturally abundant molecular catalyst, exhibits exceptional selectivity and maintains a constant current density in CO2-saturated 0.1 M KNO3. Remarkably, we achieved a Faradaic efficiency (FE) of 26.04% at −0.5 V versus the reversible hydrogen electrode (RHE), resulting in a production yield of 164.04 μg h−1 mg−1 and an impressive turnover number (TON) reaching up to 830.53 while demonstrating excellent stability and durability over a period of 50 hours. Our experimental findings are further supported by density functional theory (DFT) studies that shed light on the influence exerted by the covalently attached and redox-active benzimidazole unit within Vitamin B12 molecule itself when immobilized onto conductive surfaces like carbon nanotubes. This work represents an unprecedented example where naturally abundant vitamin has been successfully immobilized on a conductive surface for achieving highly efficient electroproduction of urea.

Self-Assembled Molecular Complexes of 1,10-Phenanthroline and 2-Aminobenzimidazoles: Synthesis, Structure Investigations, and Cytotoxic Properties.

Three new molecular complexes (phen)3(2-amino-Bz)2(H+)(BF4-)·3H2O 5, (phen)3(2-amino-5(6)-methyl-Bz)2(H+)(BF4-)·H2O 6, and (phen)(1-methyl-2-amino-Bz)(H+)(BF4-) 7, were prepared by self-assembly of 1,10-phenanthroline (phen) and various substituted 2-aminobenzimidazoles. Confirmation of their structures was established through spectroscopic methods and elemental analysis. The X-ray diffraction analysis revealed that the crystal structure of 7 is stabilized by the formation of hydrogen bonds and short contacts. In addition, the molecular geometry and electron structure of molecules 5 and 6 were theoretically evaluated using density functional theory (DFT) methods. According to the DFT B3LYP/6-311+G* calculations, the protonated benzimidazole (Bz) units act as NH hydrogen bond donors, binding two phenanthrolines and a BF4- ion. Non-protonated Bz unit form hydrogen bonds with the N-atoms of a third molecule phen. The molecular assembly is held together by π-π stacking between benzimidazole and phenanthroline rings, allowing for N-atoms to associate with water molecules. The complexes were tested in vitro for their tumor cell growth inhibitory effects on prostate (PC3), breast (MDA-MB-231 and MCF-7), and cervical (HeLa) cancer cell lines using MTT-dye reduction assay. The in vitro cytotoxicity analysis and spectrophotometric investigation in the presence of ct-DNA, showed that self-assembled molecules 5-7 are promising DNA-binding anticancer agents warranting further in-depth exploration.

Crystal structure and Hirshfeld surface analysis of a new benzimidazole compound, 3-{1-[(2-hy-droxyphen-yl)meth-yl]-1H-1,3-benzo-diazol-2-yl}phenol.

The title compound, C20H16N2O2, is composed of two monosubstituted benzene rings and one benzimidazole unit. The benzimidazole moiety subtends dihedral angles of 46.16 (7) and 77.45 (8)° with the benzene rings, which themselves form a dihedral angle of 54.34 (9)°. The crystal structure features O-H⋯N and O-H⋯O hydrogen-bonding inter-actions, which together lead to the formation of two-dimensional hydrogen-bonded layers parallel to the (101) plane. In addition, π-π inter-actions also contribute to the crystal cohesion. Hirshfeld surface analysis indicates that the most significant contacts in the crystal packing are: H⋯H (47.5%), O⋯H/H⋯O (12.4%), N⋯H/H⋯N (6.1%), C⋯H/H⋯C (27.6%) and C⋯C (4.6%).

Polybenzimidazole-based polymers of intrinsic microporosity membrane for high-temperature proton conduction

Anhydrous proton conducting polymer membrane materials have raised much attention in the application of high-temperature proton-exchange membranes (HT-PEMs) fuel cells, which convert chemical energy into electrical energy. Polybenzimidazole-based polymers, as typical materials for HT-PEMs, their compact structures result in small fractional free volumes (FFV), which is not conducive to the adsorption and retention of proton carriers. Herein, a series of polybenzimidazole-based polymers of intrinsic microporosity (PIM-PBIs) were synthesized. PIM-PBIs possess the benzimidazole units and porous structures, and have good thermal stability and large specific surface area (100 ∼ 400 m2/g). PIM-PBIs are further embedded in polyvinylidene fluoride (PVDF) to form mixed matrix membranes for high-temperature proton conduction. The resulting membranes exhibit high proton conductivity up to 90.11 mS cm−1 at 140 ℃ and high phosphoric acid (PA) retention rate of 90.0 %. This work provides a facile method for the precise design and preparation of proton-conducting porous materials.

Atmospheric Water Harvesting in Microporous Organic Polymers Constructed from Trazine and Benzimidazole Units

AbstractPorous materials‐assisted atmospheric water harvesting (AWH) approaches are attractive for addressing the severe shortage of freshwater resources. Herein, ionothermal polymerization approach was employed to realize four porous organic polymers (FJU‐CTFs) with strong hydration stability and low skeleton density for atmospheric water harvesting. The materials exhibited ultra‐high water vapor adsorption capacity (1108 cm3 g−1), s‐type adsorption isotherms, and rapid filling of water vapor in the pores of the materials under low humidity conditions. It has the characteristics of atmospheric water harvesting from the air at lower humidity (30 %–40 %) and narrow temperature (30–35 °C). A total of 30 times of water adsorption‐desorption cycles showed the excellent working ability and hydrolytic stability of FJU‐CTFs, which provided new solutions for the application of porous materials in AWH and expanded new material types.

Selective ion sensing in aqueous media with ESIPT active fluorescent probes – A particular case for hypochlorite detection

We report two ESIPT active novel fluorescent probes, 1 and 2, based on benzoxazole and benzimidazole units, respectively. Their sensing aptitude towards metal ions in aqueous media is reported. A specific response of 1 to Al3+ and, to a lesser extent, Zn2+, was found, while the emission of 2 is highly impacted by the Al3+, Cu2+, Fe2+ and Fe3+ metal ions by either a blue shift or a quenching of the emission. Emission of 2 also shows a relative sensitivity to the Ni2+ and Hg2+ cations. Anions sensing studies on 2 revealed a unique emission in presence of hypochlorite ions, while glyphosate and aminomethylphosphonic acid have the effect to decrease the emission intensity by 40% and 75%, respectively. Investigations on the recognition mechanism led to the conclusion that Al3+ was inhibiting the ESIPT process by deprotonation of the phenol group, and that a fast but weak interaction was taking place between the hypochlorite ion and 2.

Protonated benzimidazole segment induced interfacial limited linear grafting in aramid fiber/epoxy resin interface towards strong and tough composites

To induce both high strength and high toughness advantages while ensuring high interfacial grafting density is the intrinsic conflict in fiber reinforced polymer composite structure design. In this article, utilizing the alkalinity of benzimidazole contained aramid fiber (PBIA), we prepared protonated fiber surface via simple Lewis acid solution soaking to adjust polymerization process of epoxy resin matrix, and accomplished linear interfacial polymerization/grafting limited in composite interface as Atomic Force Microscopy (AFM) confirmed, thus strong and tough interface with high grafting density was obtained. As 1H NMR spectrum confirmed, protonated benzimidazole unit on fiber surface could convert interfacial molecular configuration of composite from crosslinking to linearity, where the linearity configuration dominated interfacial grafting density was also promoted due to their improved surface electron density as Differential Scanning Calorimetry (DSC) and Density Functional Theory (DFT) calculated results revealed. Therefore, ex-situ experiments like Tapered Double-Cantilever Beam (TDCB) tearing test revealed that the protonated benzimidazole segment could highly enhance interfacial tearing toughness (KⅠC) by 33.80%, where the practical interfacial shear strength (IFSS) and interfacial shear toughness (GⅠC) in the composite also respectively increased by 60.16% and 66.56% at maximum, which leaded to the optimization in mechanical strength and toughness of the composite short beam.

Solving the crystal structure of heterocyclic Poly(arylene benzimidazole) via model compound single crystal and theoretical calculations

Heterocyclic aramid containing benzimidazole units has demonstrated to be one of the strongest fibers. Due to positional isomerism of asymmetric benzimidazole and conformational isomerism of phenylamide, solving the crystal structure of poly(arylene benzimidazole) (PABI) aramid was a prominent challenge. Herein, we first reported the crystal structure of PABI aramid. First, the model compound: N-(4-(5-benzamido-1H-benzo[d] imidazole-2-yl) phenyl) benzamide (PBA) was cultured into single crystal: the molecules took a perfect ross-tenon-mortise interlocking conformation, in which the hydrogen bonding made a giant three-dimensional network. The PABI crystals with PBA crystal stacking feature were subsequently constructed and optimized through theoretical quantum calculation, disclosing a monoclinic unit cell with the parameters (a = 8.56 Å; b = 5.05 Å; and c = 36.78 Å; and β = 91.4°) and Pn space group. Their plausibility and validity were verified, since the simulated XRD and 2D-WAXD patterns reproduced the experimental XRD patterns. Our strategy of linking model compound PBA single crystals to obtain higher PABI crystals, paved the way to solving asymmetrical heterocyclic macromolecules crystals composed of easily isomerized chemical structures.

Synthesis of cationic polymer decorated with halogen for highly efficient trapping 99TcO4-/ReO4.

The elimination of anion is of great importance from radioactive nuclear waste containing 99TcO4- by rationally designing anion-scavenging materials with high density of charge and more accessible adsorption sites. Herein, a tailor-made cationic organic polymer with donor-acceptor (D-A) structure, namely TrDCPN, was successfully synthesized by rationally modifying the benzimidazole unit for efficient trapping the perrhenate (ReO4-) as a 99Tc surrogate. Systematic control of the skeleton affect enables the material to integrate a variety of features, surmounting the long-term challenge of 99TcO4-/ReO4- remediation under extreme conditions of high acid/base and high ionic strength. Furthermore, the TrDCPN shows excellent affinity toward ReO4- in the existence of large excess of competitive anions (SO42-, NO3- and PO43-etc.) as well as promising reusability for trapping ReO4-. The excellent stability and separation were derived from the introduction of large conjugated modules, triazine core and hydrophobic. More importantly, the synthetic cationic organic polymer with D-A feature was first proved that the introduction of halogen can effectively enhance the backbone charge, and increase the adsorption capacity by synergy of ion exchange, electrostatic interaction and δ hole-anion interaction. The adsorption capacity of TrDCPN can be up to 420.3mg/g and reach equilibrium within 20min. It is noteworthy that TrDCPN successfully immobilizes ReO4- from simulated Hanford waste with a high separation efficiency of 93 %, providing a new paradigm for material design to dispose of the problem of radioactive pollutants in the environment.

Synthesis and Antimicrobial Activity Evaluation of Homodrimane Sesquiterpenoids with a Benzimidazole Unit.

Herein we report a feasible study concerning the synthesis and the in vitro antimicrobial activity of some new homodrimane sesquiterpenoids with a benzimidazole unit. Based on some homodrimane carboxylic acids, on their acyl chlorides and intermediate monoamides, a series of seven N-homodrimenoyl-2-amino-1,3-benzimidazoles and 2-homodrimenyl-1,3-benzimidazoles was synthesized. The syntheses involved the decarboxylative cyclization and condensation of the said acids or acyl chlorides with o-phenylendiamine and 2-aminobenzimidazole, as well as the p-TsOH-mediated cyclodehydration of the said monoacylamides. The structures of the synthesized compounds have been fully confirmed, including by the X-ray diffraction. Their biological activities were evaluated on five species of fungi (Aspergillus niger, Fusarium solani, Penicillium chrysogenum, P. frequentans, and Alternaria alternata) and two strains of bacteria (Bacillus sp. and Pseudomonas aeruginosa). Compounds 7 and 20 showed higher antifungal (MIC = 0.064 and 0.05 μg/mL) and antibacterial (MIC = 0.05 and 0.032 μg/mL) activities compared to those of the standards: caspofungin (MIC = 0.32 μg/mL) and kanamycin (MIC = 2.0 μg/mL), and compounds 4, 10, 14, and 19 had moderate activities.

Coordination Polymer Electrocatalysts Enable Efficient CO-to-Acetate Conversion.

Upgrading carbon dioxide/monoxide to multi-carbon C2+ products using renewable electricity offers one route to more sustainable fuel and chemical production. One of the most appealing products is acetate, the profitable electrosynthesis of which demands a catalyst with higher efficiency. Here, a coordination polymer (CP) catalyst is reported that consists of Cu(I) and benzimidazole units linked via Cu(I)-imidazole coordination bonds, which enables selective reduction of CO to acetate with a 61% Faradaic efficiency at -0.59 volts versus the reversible hydrogen electrode at a current density of 400mA cm-2 in flow cells. The catalyst is integrated in a cation exchange membrane-based membrane electrode assembly that enables stable acetate electrosynthesis for 190h, while achieving direct collection of concentrated acetate (3.3 molar) from the cathodic liquid stream, an average single-pass utilization of 50% toward CO-to-acetate conversion, and an average acetate full-cell energy efficiency of 15% at a current density of 250mAcm-2 .

A Bioinspired Strategy Toward UV Absorption Enhancement of Melanin-like Polymers for Sun Protection

Open AccessCCS ChemistryRESEARCH ARTICLES5 Dec 2022A bioinspired strategy towards UV absorption enhancement of melanin-like polymers for sun protection Zhen Yang, Jianhua Zhang, Huijie Liu, Junfei Hu, Xianheng Wang, Wanjie Bai, Wei Zhang, Ye Yang, Zhipeng Gu and Yiwen Li Zhen Yang Google Scholar More articles by this author , Jianhua Zhang Google Scholar More articles by this author , Huijie Liu Google Scholar More articles by this author , Junfei Hu Google Scholar More articles by this author , Xianheng Wang Google Scholar More articles by this author , Wanjie Bai Google Scholar More articles by this author , Wei Zhang Google Scholar More articles by this author , Ye Yang Google Scholar More articles by this author , Zhipeng Gu Google Scholar More articles by this author and Yiwen Li Google Scholar More articles by this author https://doi.org/10.31635/ccschem.022.202202565 SectionsSupplemental MaterialAboutPDF ToolsAdd to favoritesDownload CitationsTrack Citations ShareFacebookTwitterLinked InEmail Due to the complexity of the structure within melanin and synthetic polymers (i.e. polydopamine, PDA), it is a challenge to regulate the UV absorptions. In nature, melanocytes could biosynthesize more pheomelanins instead of eumelanins via overexpressing proteins and genes for photoprotection when the UV irradiation is enhanced. During this biosynthetic pathway, L-cystine, transported by xCT gene, could be involved to form a new monomer structure incorporating benzothiazole group, finally resulting in the formation of UV absorptionenhanced pheomelanin. Inspired by this, we proposed a facile strategy to regulate the UV absorption of PDA by introducing the benzimidazole (BI) unit through the thiol-Michael addition reaction during the polymerization process. It was further found that the introduction of BI units not only significantly increased the content of chromophore and auxochromes, but also effectively restricted the red-shift of absorption spectrum via interrupting the conjugated microstructure within PDA, both of which contribute to the UV absorption enhancement. These UV absorption-enhanced PDA nanoparticles could be used to fabricate bioinspired sunscreens for efficient sun protection. This work will provide a facile strategy to regulating UV absorption of melanin-like materials and open new horizons for the design and construction of bio-inspired sunscreens. Download figure Download PowerPoint Previous articleNext article FiguresReferencesRelatedDetails Issue AssignmentVolume 0Issue jaPage: 1-33Supporting Information Copyright & Permissions© 2022 Chinese Chemical Society Downloaded 41 times PDF downloadLoading ...

The effect of π-linker bulk on the photophysical properties of 2-phenylfuro[2,3-b]quinoxaline-based FQ–π–FQ-type compounds

Employing a 2-phenylfuro[2,3-b]quinoxaline scaffold as a fluorophore, and phenyl, biphenyl, anthracene and benzothiadiazole as π-linkers, Ph-dFQ, bPh-dFQ, ADN-dFQ and Bth-dFQ were constructed, along with BIZ-FQ with a benzimidazole unit, to screen suitable blue emitters.

Design, Synthesis and Anti-inflammatory Activity of Azulene Derivatives Containing Benzimidazole Unit

Design, Synthesis and Anti-inflammatory Activity of Azulene Derivatives Containing Benzimidazole Unit

High strength in combination with high toughness in layered intrinsic heterocyclic aramid films via constructing liquid crystal-like structure during gelation self-assembly

The fabrication of high strength and toughness in polymeric materials, especially for rigid-chain polymers, has been a long-term technological challenge in high-performance materials design. In this work, the synthesized soluble poly (benzimidazole-terephthalamide) (PABI) acts as a rigid-chain intrinsic polymer. Then, the coordination effect of the HCl with the benzimidazole unit induces more extended PABI chains assembled into a gel network with a liquid crystal-like structure. Finally, the obtained PABI gel is further compressed into a layered film during solvent evaporation. Scanning electron microscopy images reveal that the resultant films present nacre-like morphologies. X-ray diffraction and polarized light microscopy demonstrate the formation of the liquid crystal-like structure. Owing to the highly oriented layers and the self-reinforcement of fibrils in layers, the strength (511.1 MPa) of PABI films increases by 41.7% through altering the gelation time. Ultimately, it reaches a record-high 708.7 MPa by altering HCl content. Meanwhile, the sliding and plastic deformation of amorphous interconnected layers, tearing of fibrils, crack branching, and crack deflection facilitate stable crack propagation and significantly dissipate the energy. Hence, the toughness (136.7 MJ/m3) of PABI films also increases by 23.7% through altering gelation time and remains at a high level under high HCl content. In addition, the highly oriented layered structure unexpectedly imparts PABI films with a high dielectric strength of 686.6 MV/m. Our findings provide a facile strategy for designing high-performance polymeric materials with high strength, toughness, and even more functionality.