Benign Pneumoconiosis Research Articles

Interstitial Lung Disease due to Siderosis in a Lathe Machine Worker

Since its first description in 1936, siderosis of lung has been considered a benign pneumoconiosis due to absence of significant clinical symptoms or respiratory impairment. Subsequently, authors have questioned the non-fibrogenic property of iron. However, siderosis causing interstitial lung disease with usual interstitial pneumonia (UIP) pattern has not been described in the past. We report a case of UIP on high resolution computed tomography, proven to be siderosis on transbronchial lung biopsy in a lathe machine worker.

Symptomatic pulmonary siderosis in scissors/knife sharpening worker: A case report

Pulmonary siderosis is a rare occupational lung disease. Traditionally, it has been considered a “benign pneumoconiosis” because of the absence of associated clinical symptoms or pulmonary fibrosis. However, few authors have reported the evidence of pulmonary symptoms with lung fibrosis on high-resolution computed tomography and lung biopsy. Symptomatic pulmonary siderosis in scissors/knife sharpening worker has not been described in past literature. We report a case of biopsy proven symptomatic pulmonary siderosis in scissors/knife sharpening worker, who was unnecessarily treated with antitubercular therapy for 3 months.

The Determination of Exposure to Total, Inhalable and Respirable Particles in Welders in Benin City, Edo State

In many welding processes, air pollutants are generated and take the form of dust, fume and gases. These particles generally remain suspended in air and in that way can be carried long distances from the welding arc. Plethora of studies have suggested that welding is insidious to the male reproductive system, other pernicious effect includes the development of benign pneumoconiosis, siderosis, respiratory impairment, headache, nausea, shortness of breath, muscle pain and a metallic taste in the mouth. The objectives of this study was to determine the personal exposure to total, inhalable and respirable particulate matter among welder in Benin City, subject the data to statistical analysis and compare the values obtained to the regulatory limits. The particles were captured using SKC Air Check Gravimetric Sampler. The sampling was done three times a week for six months between October 2011 to March 2012. The result showed that there was spatial variation in the measured TSP, respirable and Inhalable PM and also that the measured particulate matters were above the threshold Limit Value (TLV) in most of the locations studied except for welders in Oluku and Agbor which their TSP, Respirable and Inhalable are below this limit.

Occupational toxic risks in dental laboratory technicians

AbstractDental laboratory technicians use a wide range of materials and techniques. They are thus subject to occupational exposures of many different kinds. The aim of this review is to present the circumstances of exposure, the related risks, and the epidemiological data available in the literature. Exposures to metals, waxes, resins and silica can cause irritation or allergic reactions, affecting either the skin or the respiratory tract. The risks of benign pneumoconiosis induced by hard metals are well documented. A prevalence of 15.4% after 20 or more years of exposure has been reported, whereas the prevalence in the general population is less than 1%. Malignant pneumoconiosis is caused by dust from crystalline silica, asbestos or beryllium. Silicosis is the most common occupational disease among dental technicians, while for berylliosis the risk is not well documented. Isolated cases of systemic autoimmune diseases have been observed. No study has yet demonstrated a link between these diseases and occupational exposure of dental technicians. Silica is known to provoke systemic scleroderma, but its role in prosthetists remains to be established. The first steps in prevention are the identification, classification and evaluation of exposure and the effects of that exposure on the health of exposed workers. Reduction or elimination of exposure by collective or individual protective measures are the best modalities of prevention.Copyright © 1999 John Wiley & Sons, Ltd.

Silicosis in barium miners.

Four men who mined barytes in Scotland and who developed pneumoconiosis are described. Three developed progressive massive fibrosis, from which two died; and one developed a nodular simple pneumoconiosis after leaving the industry. The radiological and pathological features of the men's lungs were those of silicosis and high proportions of quartz were found in two of them post mortem. The quartz was inhaled from rocks associated with the barytes in the mines. The features of silicosis in barium miners are contrasted with the benign pneumoconiosis, baritosis, that occurs in workers exposed to crushed and ground insoluble barium salts. Diagnostic difficulties arise when silicosis develops in workers mining minerals known to cause a separate and benign pneumoconiosis. These difficulties are compounded when, as not infrequently happens, the silicotic lesions develop or progress after exposure to quartz has ceased.

Pneumoconiosis in Animals Exposed to Poly(Vinyl Chloride) Dust

Rats, guinea pigs and monkeys were exposed by inhalation (6 hr/day, 5 days/week) for up to 22 months to a 13 mg/m3 concentration of PVC dust. Autopsies on rats and guinea pigs were performed after 12 months of exposure and on monkeys after 22 months after 22 months of exposure. Lung function tests were performed on monkeys after 9, 14 and 22 months of exposure. Aggregates of alveolar macrophages containing PVC particles were found in the lungs of all animals. These aggregates were more numerous in the monkey lungs. No fibrosis or significant cellular infiltrates were present in or near these cellular aggregates. No significant effects on pulmonary function could be demonstrated in the monkeys exposed to PVC. Under the conditions of this experiment, inhaled PVC produced a benign pneumoconiosis.

Pneumoconiosis in animals exposed to poly(vinyl chloride) dust.

Rats, guinea pigs and monkeys were exposed by inhalation (6 hr/day, 5 days/week) for up to 22 months to a 13 mg/m3 concentration of PVC dust. Autopsies on rats and guinea pigs were performed after 12 months of exposure and on monkeys after 22 months after 22 months of exposure. Lung function tests were performed on monkeys after 9, 14 and 22 months of exposure. Aggregates of alveolar macrophages containing PVC particles were found in the lungs of all animals. These aggregates were more numerous in the monkey lungs. No fibrosis or significant cellular infiltrates were present in or near these cellular aggregates. No significant effects on pulmonary function could be demonstrated in the monkeys exposed to PVC. Under the conditions of this experiment, inhaled PVC produced a benign pneumoconiosis.

Toxicity and Health Effects of Selected Organotin Compounds: A Review

The toxicity of selected tin compounds is reviewed. Over the years, a variety of uses has been found for organic and inorganic tin compounds, as fungicides, as stablizers in plastics, moluscicides, and miticides; they have also been suggested as insect chemosterilants and for other industrial uses. Many of these products are unpalatable when mixed into diets and have been suggested as rodent repellents. Inhaling tin as dust or fumes may cause a benign pneumoconiosis in exposed workers. The organotin compounds can be divided into alkyltin and aryltin compounds. The trimethyl and triethyltin compounds are well absorbed from the gastrointestinal tract and are the most toxic in this group. Triethyltin particularly produces status spongiosus of the white matter of the central nervous system. Most of the other alkyl and aryl tin compounds are poorly absorbed from the gastrointestinal tract, and are less toxic when given orally than when given parentally. Only one compound, tricyclohexyltin hydroxide, is now registered by the Environmental Protection Agency as a miticide. This product produces skin irritation in rabbits. Studies should be conducted to determine whether it causes contact dermatitis in humans.

Toxicity and health effects of selected organotin compounds: a review.

The toxicity of selected tin compounds is reviewed. Over the years, a variety of uses has been found for organic and inorganic tin compounds, as fungicides, as stablizers in plastics, moluscicides, and miticides; they have also been suggested as insect chemosterilants and for other industrial uses. Many of these products are unpalatable when mixed into diets and have been suggested as rodent repellents. Inhaling tin as dust or fumes may cause a benign pneumoconiosis in exposed workers. The organotin compounds can be divided into alkyltin and aryltin compounds. The trimethyl and triethyltin compounds are well absorbed from the gastrointestinal tract and are the most toxic in this group. Triethyltin particularly produces status spongiosus of the white matter of the central nervous system. Most of the other alkyl and aryl tin compounds are poorly absorbed from the gastrointestinal tract, and are less toxic when given orally than when given parentally. Only one compound, tricyclohexyltin hydroxide, is now registered by the Environmental Protection Agency as a miticide. This product produces skin irritation in rabbits. Studies should be conducted to determine whether it causes contact dermatitis in humans.

Radiological changes in pneumoconiosis due to tin oxide

Summary 1. Lung changes in 121 cases from a tin smelting works are described. 2. The radiological picture varied with the job of the worker, the two principal types being widespread tiny dense shadows, and softer, larger, more nodular opacities. 3. These symptomless cases are thought to be examples of benign pneumoconiosis due to tin oxide.

Occupational medicine.

Apparently Benign Pneumoconiosis The inhalation of certain dusts may produce x-ray pictures that are alarming in appearance. However, there is no reaction to such dusts and their chief hazard is mistaken diagnosis, with resultant unnecessary anxiety and poor medical advice to the worker. Hamlin117 has recently discussed the differential diagnosis between silicosis and siderosis, the benign x-ray picture caused by inhalation of iron oxide. The term benign pneumoconiosis is applied to these cases, and the physician will do well to acquaint himself with the available facts. Hamlin and Weber118 have made clinical and chest x-ray studies of 69 foundry grinders . . .

DIAGNOSIS OF OCCUPATIONAL DISEASE

Article1 May 1947DIAGNOSIS OF OCCUPATIONAL DISEASEIRVING GRAY, M.D., F.A.C.P.IRVING GRAY, M.D., F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-26-5-678 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe modern period of interest in occupational diseases had its inception following the epoch-making publication of Ramazzini in 1700.1In this comprehensive treatise were gathered the references of his predecessors on the subject of occupational disease. Ramazzini classified the diseases of nearly 100 different occupations in which hazards to health existed. The first essay on occupational diseases in the United States was written by McCready in 18352and was recently published again.3Garrison4reviewed the literature on occupational diseases and spoke of "life as an occupational disease." In recent years there has been an increasing interest on the part of...Bibliography1. RAMAZZINI B: De morbis artificum diatriba, Modina, 1700. Google Scholar2. MCCREADY BW: On the influence of trades, professions, and occupations in the U. S., in the production of disease. Reprinted from Transactions of the Medical Society of the State of N. Y., Vol. III, Albany, 1837, p. 91-150. Google Scholar3. MILLER G: Introductory Essay to: On the influence of trades, professions, and occupations in the U. S., in the production of disease, 1943, Johns Hopkins Press, Baltimore. Google Scholar4. GARRISON FH: Life as an occupational disease, Bull. N. Y. Acad. Med., 1932, x, 679-694. Google Scholar5. SAYER HD: Occupational diseases; interpretation of compensation laws in the various States, Proceedings of Third Postgraduate Course in Industrial Medicine, L. I. College of Medicine, 1944. Google Scholar6. : Occupation Hazards and Diagnostic Signs, Bulletin No. 41, 1941. Google Scholar7. SCHWARTZTULIPAN LL: Occupational diseases of the skin, 1939, Lea & Febiger, Philadelphia. Google Scholar8. SULZBERGERFINNERUD MBCW: Industrial dermatitis; definition and criteria for diagnosis, Jr. Am. Med. Assoc., 1938, cxi, 1528-1532. CrossrefGoogle Scholar9. PECK SM: Reporting industrial dermatitis, Compensation Med., 1946, i, 3. Google Scholar10. GRAY I: Criteria for determining presence of an occupational disease. Third Post-graduate Course in Industrial Medicine, L. I. College of Medicine, Oct. 19, 1944. Google Scholar11. GRAYGREENFIELD II: Acute lead poisoning, Indust. Med., 1938, vii, 262-264. Google Scholar12. GREENBURGMOSKOWITZ LS: Safe use of solvents for synthetic rubbers, Indust. Med., 1945, xiv, 357-366. Google Scholar13. GRAYGREENFIELDLEDERER IIM: Benzene poisoning, Jr. Am. Med. Assoc., 1940, cxiv, 1325-1330. Google Scholar14. LEHMANNFLURY KBF: Toxicology and hygiene of industrial solvents, 1943, The Williams & Wilkins Co., Baltimore. Google Scholar15. GARDNER LU: The pathology and roentgenographic manifestations of pneumoconiosis, Jr. Am. Med. Assoc., 1940, cxiv, 535-545. Google Scholar16. PENDERGRASSLEOPOLD EPSS: Benign pneumoconiosis, Jr. Am. Med. Assoc., 1945, cxxvii, 701-705. CrossrefGoogle Scholar17. BERNSTEINSUSSMAN SSML: Thoracic manifestations of sarcoidosis, Radiology, 1945, xliv, 37. CrossrefGoogle Scholar18. RYDERREINEKE HWHG: Pulmonary roentgenographic changes due to mitral stenosis simulating those due to silicosis, Am. Heart Jr., 1945, xxix, 327-328. CrossrefGoogle Scholar19. : Cost of Compensation, 2 years—1938 and 1939; Spec. Bulletin No. 208, 1941. Google Scholar20. COCAWALZERTHOMMEN AFMAA: Asthma and hay fever in theory and practice, 1931, Charles C. Thomas, Springfield. Google Scholar21. GRAYALBERT IM: Prevention of asthma in industry, Indust. Med., 1943, xii, 801-804. Google Scholar22. GRAY I: Gastrointestinal disease in relation to occupational hazards; gastroenterology, Jan. 1945. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Brooklyn, New York*Presented at the 27th Annual Session of the American College of Physicians, Philadelphia, May 16, 1946. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1947Volume 26, Issue 5Page: 678-686 ePublished: 1 December 2008 Issue Published: 1 May 1947 PDF downloadLoading ...