Benefits Of Oxytocin Research Articles

Temporalities of oxytocin for labour augmentation: a mixed-methods study of time factors shaping labour practices in a busy maternity unit in Tanzania

BackgroundHigh rates of labour augmentation with oxytocin have been found in some low- and lower-middle-income countries, causing potential perinatal harm. It is critical to understand the reasons for this overuse. Aim was to explore factors that shape practices around using oxytocin for labour augmentation in a high-volume labour ward in Dar es Salaam, Tanzania.MethodsMixed-methods data collection was conducted from March 2021 to February 2022, including structured observations of 234 births, 220 h of unstructured labour ward observations and 13 individual in-depth interviews with birth attendants. Thematic network analysis and descriptive statistics were used to analyse data. We used a time-lens to understand practices of oxytocin for labour augmentation in time-pressured labour wards.ResultsBirth attendants constantly had to prioritise certain care practices over others in response to time pressure. This led to overuse of oxytocin for augmentation to ensure faster labour progression and decongestion of the, often overburdened, ward. Simultaneously, birth attendants had little time to monitor foetal and maternal condition. Surprisingly, while oxytocin was used in 146 out of 234 (62.4%) structured labour observations, only 9/234 (4.2%) women had active labour lasting more than 12 h. Correspondingly, 21/48 (43.8%) women who were augmented with oxytocin in the first stage of labour had uncomplicated labour progression at the start of augmentation. While the partograph was often not used for decision-making, timing of starting oxytocin often correlated with natural cycles of ward-rounds and shift-turnovers instead of individual women’s labour progression. This resulted in co-existence of ‘too early’ and ‘too late’ use of oxytocin. Liberal use of oxytocin for labour augmentation was facilitated by an underlying fear of prolonged labour and low alertness of oxytocin-related risks.ConclusionsTime scarcity in the labour ward often made birth attendants deviate from clinical guidelines for labour augmentation with oxytocin. Efforts to navigate time pressure resulted in too many women with uncomplicated labour progression receiving oxytocin with little monitoring of labour. Fear of prolonged labour and low alertness to oxytocin-mediated risks were crucial drivers. These findings call for research into safety and benefits of oxytocin in low-resource settings and interventions to address congestion in labour wards to prevent using oxytocin as a time-management tool.

Does Oxytocin Impact the Psychotherapeutic Process? An Explorative Investigation of Internet-Based Cognitive-Behavioral Treatment for Posttraumatic Stress Disorder

Background: Oxytocin might promote favorable psychotherapy outcomes by strengthening the therapeutic alliance. Its involvement in psychotherapeutic processes, especially regarding the therapeutic alliance, needs further investigation. Patients and Methods: Blood oxytocin of 35 male German Armed Forces service members who were seeking treatment for posttraumatic stress disorder (PTSD) was analyzed before the onset of a 5-week internet-based, trauma-focused psychotherapy. We investigated whether oxytocin influenced patients’ ratings of the therapeutic alliance components “agreement on collaboration” and “emotional bond,” assessed during and after treatment. We further explored oxytocin’s impact on general change mechanisms of psychotherapy and on psychotherapy expectation and evaluation. Results: Oxytocin had no significant impact on early agreement on collaboration, which significantly predicted psychotherapy outcome. Early emotional bond was not predicted by oxytocin and was not predictive for psychotherapy outcome. Descriptive analyses showed that patients with higher pretreatment oxytocin concentrations provided higher ratings of general change mechanisms of psychotherapy. On a descriptive level, the associations between psychotherapy expectation and evaluation and oxytocin were mixed. Discussion and Conclusion: We found positive effects of higher pretreatment oxytocin concentrations in PTSD patients. This descriptive study is limited by its small sample size and needs replication in larger, independent samples. However, results indicate possible benefits of oxytocin on trauma-focused psychotherapy.

Beeinflusst Oxytocin den psychotherapeutischen Prozess? Eine explorative Untersuchung im Kontext einer internetbasierten kognitiv-verhaltenstherapeutischen Behandlung für die posttraumatische Belastungsstörung

Hintergrund: Oxytocin könnte den Erfolg psychotherapeutischer Behandlungen erhöhen, indem es die therapeutische Allianz stärkt. Der Einfluss von Oxytocin auf den psychothe­rapeutischen Prozess, insbesondere die therapeutische Allianz, ist jedoch noch wenig erforscht. Patienten und Metho­den: Im Blut von 35 Bundeswehrsoldaten, die eine fünf­wöchige, internetbasierte, traumafokussierte Psychotherapie für die posttraumatische Belastungsstörung (PTBS) in Anspruch nahmen, wurde vor Behandlungsbeginn Oxytocin gemessen. Es wurde überprüft, ob Oxytocin die Bewertung der therapeutischen Allianz, speziell der Subkomponenten Zustimmung zur Zusammenarbeit und emotionale Bin­dung, die während und nach der Behandlung erfragt wurde, beeinflusste. Der Einfluss von Oxytocin auf weitere allgemeine Wirkfaktoren der Psychotherapie und die Psycho­therapieerwartung und -bewertung wurde exploriert. Ergebnisse: Oxytocin hatte keinen signifikanten Einfluss auf die frühe Zustimmung zur Zusammenarbeit. Diese wiederum prädizierte die Symptomreduktion. Frühe emotionale Bindung wurde nicht von Oxytocin beeinflusst und prädizierte auch die Symptomreduktion nicht. Die Deskriptivstatistiken zeigten, dass die allgemeinen Wirkfaktoren der Psychothe­rapie von Patienten mit höheren Oxytocinkonzentrationen positiver eingeschätzt wurden. Die deskriptiven Zusammenhänge zwischen Psychotherapieerwartung und -bewertung und Oxytocin fielen unterschiedlich aus. Diskussionen und Schlussfolgerungen: Es wurden positive Effekte höherer Oxytocinkonzentrationen bei PTBS-Patienten beobachtet. Die Studie ist durch ihre kleine Stichprobengröße limitiert. Ihr Schwerpunkt lag auf deskriptiven Auswertungen und sie muss an größeren, unabhängigen Stichproben repliziert werden. Sie liefert jedoch erste Hinweise für einen positiven Nutzen von Oxytocin bei traumafokussierter Psychotherapie.

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

Benefits of Oxytocin in Obstructive Sleep Apnea (OSA) Patients Using Continuous Positive Airway Pressure (CPAP) Machine

LITERATUR REVIEW : PIJAT OKSITOSIN DAN AROMA TERAPI LAVENDER MENINGKATKAN PRODUKSI ASI

Indonesia succeeded in giving exclusive breastfeeding. Breast milk that does not come out on the first day of baby's life is one of the inhibiting factors for exclusive breastfeeding entertainment. This problem can be anticipated since pregnancy through lactation counseling. Efforts to overcome problems that cannot be done in postpartum mothers in addition to breast care are with oxytocin massage and Lavender aromatherapy. Oxytocin massage for 2-3 minutes and lavender aromatherapy is an effort that can help postpartum mothers increase milk production. Lavender contains Linalool. This substance produces effects on the central nervous system (hypothalamus) which can increase the formation of breast milk, so that it can encourage exclusive breastfeeding for newborns. Literature This review aims to find out the benefits of Oxytocin and Lavender Aromatherapy to increase milk production in post partum mothers. Journal searches were conducted electronically using several databases, namely: Science Direct, Pubmed and Google Scholar from 2008 to 2018. The key words were "Oxitocyn Massage," Aromatherapy Lavender "/ Lavender Aromatherapy" and "Breast Milk Productian". The criteria used are quantitative research, complete and complete instruments. The results of the study selected articles in national journals as many as: 8 research and international journals as many as 2 studies. Complementary midwifery interventions in oxytocin massage along the spine (vertebrae) to the sixth-costae bone in the mother and lavender aromatherapy can be categorized as safe and effective enough in increasing breast milk production. Lavender oxytocin and aromatherapy massage can increase breast milk production

Oxytocin should not be used to augment labour: AGAINST: the need for oxytocin is greatest in nulliparous women.

Oxytocin used inappropriately during childbirth is dangerous to both baby and mother and is related to poor decision-making and misinterpretation of fetal wellbeing. Surprisingly though, audits of the incidence, indications, benefits and complications of oxytocin in relevant groups of women are not available. Continuous, structured and standardised labour ward audit is the only way to justify labour ward practice, as randomised trials often do not serve the purpose. Differentiating between women in spontaneous labour, induced labour or those delivered by pre-labour caesarean section is key to understanding the benefits and dangers of oxytocin. Unless a standard classification system (Robson M Best Pract Res Clin Obstet Gynaecol 2013;27:297–308) is used to continuously audit events and outcomes in labour understanding both the dangers and benefits of oxytocin will remain elusive. Audit of events and outcomes in spontaneous labour, including oxytocin to augment, can only be interpreted by knowing what proportion of the relevant cohort of women have been excluded by either having been induced or delivered by pre-labour caesarean section because the relative sizes of these three groups influence the incidences of labour events and outcome within each of the groups. More importantly, all women within the cohort must be transparently accounted for in these groups. Consensus on the definition of spontaneous and induced labour is notably lacking in modern day obstetrics and therefore the use of oxytocin specifically in spontaneous labour is often random and poorly understood. The discussion on the use of oxytocin to augment labour can be limited for practical purposes to three separate cohorts of women. These three cohorts are nulliparous women, multiparous women without a previous caesarean scar and multiparous women with a previous caesarean section scar, but all with single cephalic pregnancies at greater or equal to 37 weeks’ gestation. In delivery units that implement a continuous, structured and standardised labour ward it is clear that the incidence, indications, benefits and complications of oxytocin vary significantly in the three cohorts of women previously described. In nulliparous women the need for oxytocin to augment labour is greatest, as inefficient uterine action is the most common cause of dystocia and the incidence of caesarean section varies most between different delivery units (Brennan D Am J Obstet Gynecol 2009;201:308:e1-e8). In multiparous women without a caesarean scar the incidence of caesarean section is low, very similar between units and the incidence of oxytocin should be <5%. In multiparous women with a previous caesarean scar, the main aim should be to persuade women to attempt a short labour, and if not using oxytocin in this group of women makes this safer and simpler by reducing the chance of scar rupture, then it should be encouraged. In conclusion, each unit must decide their policy depending on their own results, which means strict implementation of labour ward audit as previously described. However, not using oxytocin to augment in nulliparous women will inevitably result in an increase in prolonged labours and an increase in operative delivery. In multiparous women the arguments for using oxytocin to augment are less persuasive and oxytocin if used should be sanctioned by a senior obstetrician. None declared. Completed disclosure of interests form available to view online as supporting information. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage

Prophylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage