The aim of this study is to report on the impact of physical activity in a palliative manner on the quality of life of people with Alzheimer's disease (AD). A literature review was conducted using scientific journal articles, theses, dissertations, and scientific websites that were evaluated for the present study. The bibliographic survey was carried out by consulting the following scientific databases: PubMed, Scielo, BVS Brasil. The search was retrospective, limiting itself to scientific papers published from February 2010 to February 2023. Physical activity can delay the expression of symptoms and cognitive impairment of AD, as well as increase protective mechanisms such as the release of neurotrophins and the hormone irisin. The combination of drug therapy with physical activity can also improve the quality of life of patients. Some studies indicate that light and moderate activities can contribute to the reduction of deficits in daily living activities and attenuate sleep disorders. Other studies show that physical activity can improve cognitive function, balance, and reduce the risk of falls in elderly people with AD. Walking seems to be a particularly beneficial physical activity for patients with AD. Although the studies presented in this review strongly indicate the benefits of physical activity for patients with AD, more research is needed to better elucidate the pathophysiology and treatment of the disease.