Behavioral Inhibition System Sensitivity Research Articles

Differences in Approach and Avoidance Motivation Sensitivities Predicting Participation and Performance in Strength Sport

Abstract Cusimano, K, Freeman, P, Moran, J, and Yamaguchi, M. Differences in approach and avoidance motivation sensitivities predicting participation and performance in strength sport. J Strength Cond Res 38(1): 180–184, 2024—Gray's Reinforcement Sensitivity Theory proposes that individual differences in behavior are due to the sensitivity to 2 brain systems: the behavioral inhibition system (BIS), which regulates aversive emotions to threatening stimuli, and the behavioral approach system (BAS), which regulates positive emotions toward rewarding or nonpunishing stimuli. The current study investigated whether BIS and BAS sensitivity predicts participation and performance in strength sports. A sample of 177 competitive strength athletes (male = 148; female = 29; mean age = 28.68; SD = 6.24 years) and 178 control participants (male = 89; female = 89; mean age = 29.39; SD = 7.42) completed the BIS/BAS scale, with strength athletes also providing their Wilks scores as a measure of sporting performance. Independent t tests showed significantly higher BIS (MD = 2.37, p = 0.003, 95% CI [0.79, 3.94], d = 0.31) and total BAS (MD = 11.71, p < 0.001, 95% CI [9.26, 14.15], d = 1.00) sensitivity in strength athletes than individuals in the control group. A 3-step hierarchical regression analysis revealed that the number of training years (β = 0.506, p < 0 .001), BIS (β = −203, p = 0.005) and BAS drive (β = 0.188, p = 0.012) made significant unique contributions to predicting the Wilks score, with no significant contributions of age, sex, BAS fun seeking, and BAS reward responsiveness. The findings indicate that the overall reward sensitivity (total BAS score) and reward seeking (BAS drive) are associated positively with participation and performance in strength sports, respectively. Given the association of these brain systems to addiction and other psychiatric disorders, the findings could have implications in psychiatric treatment and sporting recruitment.

Midfrontal conflict theta and parietal P300 are linked to a latent factor of DSM externalising disorders.

Psychiatric illnesses form spectra rather than categories, with symptoms varying continuously across individuals, i.e., there is no clear break between health and disorder. Dimensional measures of behaviour and brain activity are promising targets for studying biological mechanisms that are common across disorders. Here, we assessed the extent to which neural measures of the sensitivity of the three biological systems in the reinforcement sensitivity theory (RST) could account for individual differences in a latent general factor estimated from symptom counts across externalising disorders (EXTs). RST explanatory power was pitted against reduced P300, a reliable indicator of externalising per previous research. We assessed 206 participants for DSM-5 EXTs (antisocial personality disorder, conduct disorder, attention-deficit/hyperactivity disorder, intermittent explosive disorder symptoms, alcohol use disorder, and cannabis use disorder). Of the final sample, 49% met diagnostic criteria for at least one of the EXTs. Electroencephalographic measures of the sensitivities of the behavioural activation system (BAS), the fight/flight/freeze system, and the behavioural inhibition system (BIS), as well as P300 were extracted from the gold bar-lemon and stop-signal tasks. As predicted, we found that low neural BIS sensitivity and low P300 were uniquely and negatively associated with our latent factor of externalising. Contrary to prediction, neural BAS/"dopamine" sensitivity was not associated with externalising. Our results provide empirical support for low BIS sensitivity and P300 as neural mechanisms common to disorders within the externalising spectrum; but, given the low N involved, future studies should seek to assess the replicability of our findings and, in particular, the differential involvement of the three RST systems.

Psychological distress in a sample of predominately white female college students: the role of mindfulness and physical activity

Objective: Framed in Reinforcement Sensitivity Theory, this study examined the moderating effects of mindfulness and moderate-to-vigorous physical activity (MVPA) on the relationship between behavioral inhibition system (BIS) sensitivity and psychological distress in college students. Participants: Undergraduate students (n = 183) at a large public university in the United States were included in the study. Methods: Self-reported BIS sensitivity, mindfulness, MVPA, and psychological distress were examined in November 2021. Results: Findings revealed a positive relationship between BIS sensitivity and psychological distress, however, this relationship was conditional on levels of mindfulness and MVPA. Specifically, increased reports of mindfulness and MVPA related to lower psychological distress for participants with higher than average BIS sensitivity. Conclusions: Mindfulness and MVPA are buffers for university students prone to psychological distress. Identifying diverse strategies that effectively lower psychological vulnerabilities in college students can be used to develop targeted interventions that reduce psychopathology and promote mental health.

Relations of behavioral inhibition and activation system sensitivities with vaccination outcomes: Investigating the mediating role of vaccine hesitancy in older adults.

The study of behavioral inhibition system (BIS) and behavioral activation system (BAS) sensitivities has produced a multitude of models and frameworks to better understand decision-making and behavior. We extend this research to the study of a vaccination by exploring the relation of BIS and BAS sensitivities with vaccination willingness, receipt, and word-of-mouth. We also assess whether dimensions of vaccine hesitancy mediate these relations, testing whether they are viable explanatory mechanisms. By conducting a multi-wave survey study, our results support that BIS sensitivity does not meaningfully relate to vaccine hesitancy or vaccination outcomes. On the other hand, BAS sensitivity related to detrimental vaccination outcomes, and these effects were mediated by vaccine hesitancy dimensions associated with perceptions that vaccines cause health risks and are not needed for healthy individuals. Based on extant BIS and BAS theory, these results suggest that certain people may see refraining from vaccination as a nonpunishment.

Youth Dating Violence, Behavioral Sensitivity, and Emotional Intelligence: A Mediation Analysis.

Intimate partner violence is a multidimensional phenomenon encompassing psychological, physical, and sexual components. Violence in young couples is common in our society. This kind of violence is usually bidirectional, which adds to its complexity. This study aimed to explore how victimization (in three dimensions: non-abuse, technical mistreatment, and mistreatment) and perpetration (in two dimensions: non-perpetrator and perpetrator) are related to the BIS (Behavioral Inhibition System)/BAS (Behavioral Approach System), and it also evaluated if the dimensions of emotional intelligence (EI) (emotional attention, clarity, and regulation) mediate this relationship. Violence was evaluated in 272 young volunteer participants, as well as BIS/BAS behavioral sensitivity and perceived emotional intelligence. The correlations between these variables were analyzed, and a mediation analysis was also conducted. The results show that victimization (of the sexual and coercive type) was associated with less BAS activation, while victimization (of the sexual, humiliation, and detachment types) was associated with less BIS activity. All types of victimization were associated with less EI, specifically with less emotional clarity. Aggression (of the sexual, humiliation, detachment, and coercion types) was related to lower BAS and higher BIS sensitivity. Detachment aggression was associated with low emotional clarity. In conclusion, relationships between victimization and perpetration are evidenced in terms of BIS/BAS sensitivity and EI. Specifically, the dimension of EI emotional clarity acts as a mediator of BIS activation in victims of detachment.

Association of polymorphisms rs4680 of the Catechol-O-Methyltransferase gene and rs6265 of the brain derived neurotrophic factor gene with the behavioral inhibition and behavioral activation systems

The Behavioral Inhibition System (BIS) comprises limbic circuitry implicated in avoidance behaviors. Its increased activation has been identified as a risk factor for anxiety and depressive disorders. In addition, both Catechol-O-Methyltransferase (COMT) and Brain Derived Neurotrophic Factor (BDNF) have been postulated as candidate genes that constitute a vulnerability for the onset of anxiety and depressive disorders. The aim of this study was to evaluate the possible association between the rs4680 polymorphism of the COMT gene and the rs6265 polymorphism of the BDNF gene with the BIS and the Behavioral Activation System (BAS) in a population sample from Colombia. Genetic information was obtained by extracting DNA from blood samples of 80 participants and using Taqman probes designed for each polymorphism. In addition, participants completed a BIS/BAS scale in order to establish a neuropsychological classification. The frequency of the Met allele of the BDNF gene was greater in the group with BIS sensitivity compared to the group with BAS sensitivity. On the contrary, the frequency of the Met allele of the COMT gen did not show a significant association with the BIS. The rs6265 polymorphism of BDNF gene is associated with the BIS which in turn constitutes a risk factor for anxiety and depression.

The Behavioral Inhibition System as a Mediator between Child Sexual Abuse and Perceived Pornography Addiction in Adulthood

Worldwide, an estimated 12.7% of children have experienced child sexual abuse (CSA). CSA can lead to mental health, emotional, and behavioral consequences that often persist into adulthood such as depression, post-traumatic stress disorder, suicidal ideation, and maladaptive sexual functioning (e.g. sexual avoidance, compulsivity). Research suggests that CSA may lead to unhealthy pornography use, a form of maladaptive sexual functioning, in adulthood, though the psychological pathways governing this relationship are unexplored. In this study, 182 United States-based individuals (mean age 36.637 [SD = 11.333] years, 51.648% men) were surveyed using Amazon MTurk regarding CSA history and perceived cyberpornography addiction. Participants also completed the Reinforcement Sensitivity Theory Personality Questionnaire (RST-PQ). We found that individuals who experienced CSA reported higher perceived cyberpornography addiction scores. Serial mediation model results indicated that the behavioral inhibition system (BIS) mediated the relationship between CSA and perceived cyberpornography addiction. The BIS is a dimension of the RST-PQ which resolves conflicts between the behavioral activation system (coordinates approach behaviors) and the flight-fight-freeze system (coordinates retreat behaviors) and is associated with trait anxiety. These findings contribute to the literature on the costs of CSA and identifies BIS sensitivity as a psychological system that can be targeted in therapeutic settings to reduce maladaptive engagement with pornography by CSA survivors.

The Association Between Prenatal Maternal Stress and Adolescent Affective Outcomes is Mediated by Childhood Maltreatment and Adolescent Behavioral Inhibition System Sensitivity

Prenatal maternal stress is linked to offspring outcomes; however, there is little research on adolescents, behavioral, transdiagnostic outcomes, or the mechanisms through which relations operate. We examined, in N = 268 adolescents (Mage = 15.31 years; SD = 1.063; 57.8% boys) whether prenatal maternal stress is associated with adolescent affective outcomes; whether this association is mediated, serially, by childhood home atmosphere and adolescent behavioral inhibition system (BIS) sensitivity; and whether mediational effects are moderated by adolescent attention-deficit/hyperactivity disorder or maternal internalizing symptomology. Prenatal maternal daily stress and major life events were associated with adolescent outcomes through childhood negative atmosphere/neglect and BIS sensitivity, with no evidence of moderation. Results have implications regarding the effect of prenatal maternal stress on offspring outcomes and regarding corresponding sensitive periods.

Signaling High Sensitivity to Influence Others: Initial Evidence for the Roles of Reinforcement Sensitivity, Sensory Processing Sensitivity, and the Dark Triad.

Signaling high sensitivity to others may help individuals with heightened sensitivity to stimuli to craft their social relations to a preferred activation level ("assertive signaling of specific needs" hypothesis). Signaling sensitivity could be also a deceptive strategy helping to extract resources or obtain the desired treatment ("deceptive signaling" hypothesis). The study presents the construction of the measure of signaling high sensitivity to influence others and an initial test of both hypotheses. Two hundred and one participants ranging in age from 18 to 67 (M = 25.6; SD = 7.03) reported on their reinforcement sensitivity (behavioral approach and inhibition system), sensory processing sensitivity, and the Dark Triad. Signaling high sensitivity to influence others was weakly, but significantly, associated with behavioral inhibition system sensitivity, which was consistent with the "assertive signaling of specific needs" hypothesis. The behavioral approach system was positively correlated with signaling high sensitivity, which indicated that this influence strategy could be treated as an assertive self-presentational strategy helping in achieving social rewards for individuals with high reward responsiveness. Narcissism and psychopathy accounted for an additional amount of variance in signaling high sensitivity over and beyond reinforcement sensitivity. This was consistent with the "deceptive signaling" hypothesis. Signaling high sensitivity could be regarded as a strategy to achieve social goals using deception rather than as an expression of sensitive personality.

Effects of the Interaction between Affective Temperaments and BIS/BAS on Depressive Symptoms in Individuals with Major Depressive Disorder.

Depressive symptoms (DepS) associated with major depressive disorder (MDD) are influenced by affective temperaments (ATs), behavioral inhibition system (BIS), and behavioral activation system (BAS). However, the effect of interactions between ATs and BIS/BAS on DepS in MDD remains poorly understood. Herein, we aimed to investigate the effects of these interactions. The Temperament Evaluation of Memphis, Pisa, Paris, and San Diego Auto-questionnaire (TEMPS-A), BIS/BAS questionnaire, and Patient Health Questionnaire-9 (PHQ-9) were used to evaluate ATs, BIS/BAS, and DepS, respectively, in 90 participants with MDD. Data were analyzed using hierarchical multiple regression analysis to assess the interaction effect. The interaction (β = 0.199, p < 0.05) between depressive temperament (DepT) (β = 0.319, p < 0.01) and BIS scores (β = 0.300, p < 0.01) exhibited a significant positive effect on DepS (ΔR2 = 0.038, p < 0.05). However, the interaction between ATs and BAS scores did not exhibit a significant effect on DepS. Our findings suggest that interactions between BIS sensitivity and DepT worsen DepS in individuals with MDD. Hence, to manage DepS associated with BIS sensitivity and DepT, evaluating their interaction may be useful in daily clinical practice. This study presents important insights into MDD psychopathology.

Locus of Control as a Mediator of the Relationships Between Motivational Systems and Trait Anxiety.

The Reinforcement Sensitivity Theory, first proposed by Gray and later revised, describes three motivational systems: Behavioral Inhibition System (BIS), Behavioral Activation System (BAS), and Fight-Flight-Freeze System (FFFS). Studies have shown that high BIS and FFFS activation are positively related to anxiety symptoms, yet the relationship between BAS and anxiety remains unclear. Research data have also suggested that anxiety symptoms occur with the loss of perceived control. Thus, although studies on the direct effect of locus of control (LOC) on trait anxiety have accumulated for many years, the issue of how LOC may mediate the relationship between BIS/BAS/FFFS sensitivity and anxiety has not been addressed. This study aimed to explore the mediating role of LOC orientation on trait anxiety among young adults in association with these three motivational systems. Cross-sectional data were obtained from 422 volunteers. The BIS/BAS Scale, Trait Anxiety Inventory, and Rotter's Internal-External LOC Scale were applied. A series of mediation analyses were performed to estimate total, indirect, and direct effects. The results showed that BIS and FFFS positively predicted trait anxiety. In addition, LOC positively predicted trait anxiety and BIS. The results of the mediation analyses indicated that LOC functioned as a partial mediator between BIS and trait anxiety. This finding revealed that a high BIS level, one of the motivational systems, was associated with external LOC, which in turn contributed to reporting high trait anxiety in young adults. Hence, BIS and external LOC orientation could be suggested as risk factors for trait anxiety. As the external LOC orientation of individuals with high punishment sensitivity increased, their trait anxiety levels also increased. Therefore, it was suggested that it might be useful to be aware that LOC orientations of individuals with BIS sensitivity may pose a risk for trait anxiety.

Anxious activism: The role of behavioral inhibition system in the radicalization process

Many individuals that engage with “terroristic content” do so in online settings. Most research on online exposure to dangerous materials focuses on the content and who is posting it, and thus there is a lack of understanding on what individual traits motivate individuals to engage with extreme online content. The Behavioral Inhibition System (BIS) controls motivations to withdraw from a stimulus and can coordinate anxiety responses to acts of terrorism (Carver, 2004). However, anxiety (and therefore the BIS) can also motivate individuals to engage further with terroristic material and/or groups via the “quest for significance” (Kruglanski et al., 2014). As such, individual differences in BIS functioning may play a role in governing the relationship between exposure to extremist content and motivations to engage in extremist behavior. Using an experimental survey design in which individuals are exposed to terroristic content in an online setting, this study explores the role of BIS sensitivity in the willingness to engage with terroristic content and individual differences in ensuing activism and radicalism intentions. In support of our hypotheses, BIS sensitivity predicted increased intentions towards radicalism and activism in support of a terrorist group after exposure to terroristic content online. These findings support the quest for significance model, which posits that existential anxiety can play a role in motivating individuals toward radicalization and violent extremism.

Vaping motivations: Association of behavioral inhibition and behavioral activation systems with nicotine and cannabis vaping among adolescents

BackgroundDespite copious information on the hazards of nicotine and cannabis, many adolescents report vaping nicotine and cannabis. To advance knowledge on the precursors of vaping behaviors, this study examined the association of behavioral inhibition system (BIS) and behavioral activation system (BAS) sensitivities with nicotine and cannabis vaping among adolescents. MethodsData were part of a longitudinal survey on substance use and mental health among adolescents and included 2,467 11th grade students from 10 public high schools in California. Participants completed a 20-item scale assessing BIS (one aspect) and BAS (three aspects: drive, fun-seeking, reward responsiveness) sensitivities at baseline and reported their past 30-day nicotine and cannabis vaping at baseline and again at 6-month follow-up. Unadjusted and adjusted (controlled for demographic characteristics and product-specific baseline vaping) regression models estimated vaping risk at follow-up by BIS/BAS scores at baseline. ResultsBivariate analyses showed participants who vaped nicotine had significantly higher drive and fun-seeking scores (p < 0.05); and cannabis vapers had lower BIS and reward responsiveness scores (p < 0.05) compared to non-users. Higher fun seeking scores was associated with increased odds (OR = 1.15, 95 %CI = 1.03–1.29) of nicotine vaping and higher reward responsiveness scores reduced odds (OR = 0.89, 95 %CI = 0.79–0.99) of nicotine vaping. Higher scores on BIS was associated with decreased the odds (OR = 0.91, 95 %CI = 0.84–0.99) of cannabis vaping. ConclusionDifferent behavioral motivations should be targeted when developing interventions designed to reduce nicotine and cannabis vaping among diverse adolescents.

Temperamental Change in Adolescence and Its Predictive Role on Anxious Symptomatology.

Growing evidence supports the hypothesis that temperamental traits are not static throughout adolescence. The known links between both reactive and regulatory temperament and anxiety symptoms should be investigated bearing this hypothesis in mind. This study collected self-reported data on behavioral inhibition system (BIS) sensitivity, attentional control (AC), and anxiety symptomatology, from 296 adolescents (64.2% girls; M = 12.96 years at the first assessment, SD = 0.47) every six months, four times over eighteen months. The relationships between temperament factors (AC and BIS sensitivity), considered longitudinally (by means of their trajectories) and anxiety symptoms were investigated using Multigroup Latent Growth Modeling (MLGM), as well as the mediating effect of sex on trajectories and anxiety. BIS sensitivity decreased over time and showed differential patterns across sexes. AC remained relatively stable and we found no sex influence on its trajectory. On the other hand, we observed that the BIS sensitivity trajectory was a significant predictor of anxiety symptomatology at age 15. In conclusion, temperamental changes between the ages of 13 and 15 seem to play a relevant role in explaining subsequent anxiety symptomatology, under the mediating influence of sex.

The role of dispositional reinforcement sensitivity and self-esteem in social interaction anxiety and social phobia

Social anxiety is related to normal variation in personality and manifests as anxiety concerning interactions with others (social interaction anxiety), and/or as a fear of social scrutiny whilst performing tasks when under observation from others (social phobia). In revised Reinforcement Sensitivity Theory (rRST) a behavioral inhibition system (BIS) facilitates defensive approach behaviors and anxiety in situations of uncertainty. A fight-flight-freeze system (FFFS) facilitates fear and avoidance behaviors, and a behavioral approach system (BAS) facilitates anticipated reward and/or approach-based behaviors. rRST suggests that a socially anxious phenotype would experience elevated BIS sensitivity, elevated FFFS sensitivity, and dampened BAS sensitivity. We used self-report measures to test if the effects of social interaction anxiety and social phobia (which reflects the fear of social scrutiny) are separable within rRST, as in rRST anxiety and fear are separate constructs. Low levels of self-esteem are a risk factor for social anxiety, thus we tested how two sub-components of self-esteem referred to as self-acceptance and self-assessment predict social interaction anxiety and social phobia. 405 participants (mean age = 30.6; 86% female) completed the online study. Social interaction anxiety and social phobia were positively correlated with BIS and FFFS-flight sensitivity, and were negatively correlated with BAS, and FFFS-fight sensitivity in males and females. Social interaction anxiety and social phobia were negatively correlated with self-acceptance in males and females. Multiple regression showed that for females BIS and FFFS-flight scores were prominent positive predictors of social interaction anxiety whereas BIS was a prominent positive predictor of social phobia. For males the FFFS-fight subscale was a prominent negative predictor of social interaction anxiety. Overall, a synthesis of the present study and previous studies suggests that there may be subtle differences in how trait social interaction anxiety and trait social phobia relate to reinforcement sensitivity.

The unbalanced behavioral activation and inhibition system sensitivity in internet gaming disorder: Evidence from resting-state Granger causal connectivity analysis

BackgroundPatients with behavioral or substance addiction show an unbalanced behavioral activation system (BAS) and behavioral inhibition system (BIS) sensitivity. However, the relationship between internet gaming disorder (IGD) and BAS/BIS is obscure and the neurobiological mechanism underlying this relationship remains unclear. MethodsWe recruited 154 IGDs and 229 recreational game users (RGUs) in the current study. First, we explored the relationship between BAS/BIS and IGD. Second, subjects were subdivided into subgroups by BAS/BIS sensitivity. Third, whole-brain Granger causal connectivity (GCC) of striatum and amygdala subdivisions was estimated for the subgroup. Fourth, mediation analysis was performed to explore the role of connectivity in the relationship between IGD and BAS/BIS sensitivity. ResultsWe found the IGD group scored higher than the RGU on BIS and BASf (fun-seeking) sensitivity. Then, we identified 4 (2*2) subgroups: low/high risk of IGD with low/high BAS/BIS sensitivity groups. Two-way ANCOVA main results of interaction effects showed that in the high BAS/BIS group, the RGU exhibited increased strength in the GCC from the left putamen to the right cuneus, and the IGD exhibited decreased strength in the GCC from the right medial frontal gyrus to the caudate, from the left superior frontal gyrus to the centromedial amygdala, and from the right superior parietal lobule to the left laterobasal amygdala. Moreover, the GCC from the centromedial amygdala to the middle frontal gyrus mediated the directional relationship between BIS and IAT (Young's internet addiction test) scores. ConclusionsThe IGD individuals exhibited higher BIS and BAS-fun seeking sensitivity. Moreover, IGD with unbalanced BAS/BIS sensitivity exhibited alternative connectivity patterns involving amygdala and striatum subdivisions. These findings suggest a neurobiological mechanism for an alternation between IGD and RGU with different BAS/BIS sensitivity.

Personality traits and mental health of social networking service users: A cross-sectional exploratory study among Japanese undergraduates

In this study, we investigated personality and mental health variables for users of three popular social networking services (SNS): Twitter, Instagram, and Facebook, among Japanese undergraduate students (N = 1030). Compared to non-users, Twitter users scored significantly lower in extraversion, conscientiousness, openness, and self-esteem, and higher in neuroticism, behavioral inhibition system (BIS) sensitivity, and social comparison orientation. Instagram users scored significantly higher in extraversion, behavioral approach system (BAS) -drive, BAS-reward responsiveness, BAS-fun seeking, narcissism, self-esteem, and subjective happiness, and lower in neuroticism, anxiety, and to a marginal extent, depression. Facebook users scored significantly higher in extraversion, openness, BAS-fun seeking, self-esteem, and to a marginal extent, narcissism. Within SNS users, extraversion, agreeableness, and self-esteem were negatively associated with negative mental health variables, and positively associated with positive mental health variables. Neuroticism was positively associated with negative mental health variables, and negatively associated with positive mental health variables. Further, some associations were found within specific SNS users. Differences in personality and mental health were discussed based on the characteristics of each SNS platform.

BIS sensitivity, BAS sensitivity, and recent suicide attempts

Suicide attempts are motivated by the desire to escape aversive states and circumstances, suggesting they may be regulated by the behavioral inhibition system (BIS). Suicide attempts are also associated with reward pursuit, however, implicating a role for the behavioral activation system (BAS). We hypothesized that the interaction of high BIS and BAS sensitivity would be associated with increased risk of past-month suicide attempt. 10,625 adults completed an anonymous online survey assessing BIS sensitivity, BAS sensitivity, past-month suicidal ideation and suicide attempts, and relevant covariates. Results of logistic regression modeling yielded a statistically significant BIS-BAS interaction in the full sample and the subset of participants reporting past-month suicidal ideation (n = 489). At low BIS levels, BAS sensitivity was negatively correlated with suicide attempts; at mean BIS levels, BAS sensitivity was not correlated with suicide attempts; and at high BIS levels, BAS sensitivity was positively correlated with suicide attempts. Results suggest that vulnerability to suicide attempts may be increased among people with heightened reward responsiveness (i.e., high BAS sensitivity) when they experience competing incentives (i.e., high BIS sensitivity). Implications for clinical practice and the prevention of suicide are discussed.

Are reinforcement sensitivity personality constructs and attentional control important predictors of restrictive disordered eating?

The revised Reinforcement Sensitivity Theory (rRST) perspective on personality suggests that a neuropsychological behavioural inhibition system (BIS), behavioural approach system (BAS), and a fight-flight-freeze system (FFFS) produce the key personality traits involved in approach and avoidance behaviours. This perspective on personality can be used as a framework for understanding psychopathology. Self-report research on rRST suggests that restrictive disordered eating relates to elevated BIS sensitivity, elevated FFFS sensitivity, and possibly dysfunctional BAS sensitivity. Disordered eating can also relate to reduced trait mindfulness, which is a broadly defined construct. Trait mindfulness is positively correlated with attentional control (AC) which is a more specific component of our cognitive architecture that incorporates attentional focusing and attentional shifting processes. It is unknown how BIS and AC interact to predict restrictive disordered eating. We tested how self-reported BIS, BAS, and FFFS sensitivity, AC, and trait mindfulness relate to restrictive disordered eating in 464 healthy participants, and 177 participants with a history of psychiatric disorder. We provide new evidence that elevated restrictive disordered eating relates to reduced self-reported AC abilities (in addition to elevated BIS, and elevated FFFS sensitivity). We illustrate that the combination of high BIS and low AC predicts high levels of restrictive disordered eating (but not in all participants), whereas low BIS and high AC predicts lower levels of restrictive disordered eating (but not in all participants). We discuss how understanding the relationship between personality and attentional control can inform the design of future intervention studies.

Electrocortical Effects of Acetaminophen during Emotional Picture Viewing, Cognitive Control, and Negative Feedback.

Acetaminophen, the active ingredient in Tylenol, may have psychological effects, such as reducing social and emotional pain. The current study (N = 173) used electroencephalography (EEG) to extend past research on acetaminophen. Healthy undergraduate students (64.7% women, age M = 18.15, SD = 3.33) were randomly assigned to ingest 1,000 mg of acetaminophen or placebo before completing emotional picture viewing (n = 143), a flanker task (n = 69), and a probabilistic learning task (n = 143) while EEG was recorded. (Sample sizes used for the analyses of each task differ from the total N due to data loss.) We observed standard event-related potentials (ERPs), including emotion-modulated late positive potentials during picture viewing and feedback-related negativity during feedback on the probabilistic learning task. We also observed standard error-related and conflict-related ERPs in the flanker task but could not adequately assess acetaminophen's effect on flanker ERPs due to excessive data loss. Acetaminophen did not alter any of the ERPs, in contrast to predictions based on prior research. Exploratory analyses revealed that acetaminophen reduced the relationship between trait behavioral inhibition system sensitivity and emotion-modulated late positive potentials. Together these findings suggest that a standard dose of acetaminophen did not reliably alter neural indicators of emotional or feedback processing. Instead, preliminary findings from our study suggested that a more nuanced relationship may exist between acetaminophen and individual differences in emotional processing, although this latter finding calls for further replication.