Bipolar disorder (BD) is a disorder significantly impacts individuals worldwide, marked by alternating episodes of mania and depression. The onset and progression of the disease are impact by a interplay of genetic factors, neurobiological differences, environmental stressors, hormonal imbalances, and circadian rhythm disruptions. These factors collectively contribute to the manifestation and exacerbation of the disorder. The disorder profoundly affect both mental and physical health. The pervasive impact on daily life can be overwhelming, resulting in severe emotional distress. This distress is compounded by the high risk of suicide associated with the disorder, underscoring the critical need for vigilant care and comprehensive support to ensure the well-being of affected individuals. Effective treatment requires a holistic approach combining pharmacological interventions, psychotherapy, and lifestyle adjustments. Mood stabilizers, antipsychotics, and antidepressants, alongside Cognitive Behavioral Therapy (CBT), psychoeducation, and family therapy, form the cornerstone of treatment. Lifestyle modifications, including regular exercise, adequate sleep, and balanced nutrition, are crucial for symptom management. Electroconvulsive Therapy (ECT) is considered for severe cases. This review underscores the need for continuous research and innovation in therapeutic strategies and emphasizes bridging global disparities in mental health services to ensure equitable care and improve the well-being of people with bipolar disorder.